Phospholipase Cδ1 regulates cell proliferation and cell-cycle progression from G1- to S-phase by control of cyclin E-CDK2 activity

Biochemical Journal

Volumn 415, Issue 3, 2008, Pages 439-448

  Kaproth Joslin, Katherine A ^a   Li, Xiangquan ^a   Reks, Sarah E ^a   Kelley, Grant G ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

Cell cycle; Cyclin E; Cyclin dependent kinase 2 (CDK2); P27; Phosphoinositide specific phospholipase C; Rat 1 Fibroblast; RNA interference

Indexed keywords

CELL CYCLE; CYCLIN E; CYCLIN-DEPENDENT KINASE 2 (CDK2); P27; PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C; RNA INTERFERENCE;

CELL CULTURE; CELL DEATH; CELL PROLIFERATION; FIBROBLASTS; NUCLEIC ACIDS; TISSUE;

RNA;

ACTIN; BROXURIDINE; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; DOXYCYCLINE; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C DELTA1; PROPIDIUM IODIDE; SHORT HAIRPIN RNA; PHOSPHOLIPASE C DELTA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SENESCENCE; ANIMAL; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; RAT;

RATTUS;

ANIMALS; CELL PROLIFERATION; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; G1 PHASE; HUMANS; MICE; NIH 3T3 CELLS; PHOSPHOLIPASE C DELTA; PHOSPHORYLATION; RATS; RNA INTERFERENCE; S PHASE;

EID: 58149168619     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080233     Document Type: Article

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