-
1
-
-
0015879604
-
Ionic blockage of sodium channels in nerve
-
Woodhull, A. M. 1973. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61:687-708.
-
(1973)
J. Gen. Physiol
, vol.61
, pp. 687-708
-
-
Woodhull, A.M.1
-
2
-
-
0016624553
-
Ionic selectivity of Na and K channels of nerve membranes
-
G. Eisenman, editor. Marcel Dekker, Inc, New York
-
Hille, B. 1975. Ionic selectivity of Na and K channels of nerve membranes. In Membranes - A Series of Advances. G. Eisenman, editor. Marcel Dekker, Inc., New York. 255-323.
-
(1975)
Membranes - A Series of Advances
, pp. 255-323
-
-
Hille, B.1
-
3
-
-
61349185271
-
Competition, saturation and inhibition - ionic interaction shown by membrane ionic currents in nerve, muscle and bilayer systems
-
French, R. J., and W. J. Adelman, Jr. 1976. Competition, saturation and inhibition - ionic interaction shown by membrane ionic currents in nerve, muscle and bilayer systems. Curr. Topics Mem. Trans. 8:161-207.
-
(1976)
Curr. Topics Mem. Trans
, vol.8
, pp. 161-207
-
-
French, R.J.1
Adelman Jr., W.J.2
-
4
-
-
0015784454
-
The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine
-
Strichartz, G. R. 1973. The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J. Gen. Physiol. 62:37-57.
-
(1973)
J. Gen. Physiol
, vol.62
, pp. 37-57
-
-
Strichartz, G.R.1
-
5
-
-
0028068565
-
Amine blockers of the cytoplasmic mouth of sodium channels: A small structural change can abolish voltage dependence
-
Zamponi, G. W., and R. J. French. 1994. Amine blockers of the cytoplasmic mouth of sodium channels: a small structural change can abolish voltage dependence. Biophys. J. 67:1015-1027.
-
(1994)
Biophys. J
, vol.67
, pp. 1015-1027
-
-
Zamponi, G.W.1
French, R.J.2
-
6
-
-
0030058733
-
Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: An electrostatic approach to channel geometry
-
French, R. J., E. Prusak-Sochaczewski, G. W. Zamponi, S. Becker, A. S. Kularatna, and R. Horn. 1996. Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: an electrostatic approach to channel geometry. Neuron. 16:407-413.
-
(1996)
Neuron
, vol.16
, pp. 407-413
-
-
French, R.J.1
Prusak-Sochaczewski, E.2
Zamponi, G.W.3
Becker, S.4
Kularatna, A.S.5
Horn, R.6
-
7
-
-
58149161250
-
Trans-channel interactions in batrachotoxin-modified rat skeletal muscle sodium channels. Kinetic analysis of mutual inhibition between μ-conotoxin GIIIA derivatives and amine blockers
-
Ma, Q., E. Pavlov, T. Britvina, G. W. Zamponi, and R. J. French. 2008. Trans-channel interactions in batrachotoxin-modified rat skeletal muscle sodium channels. Kinetic analysis of mutual inhibition between μ-conotoxin GIIIA derivatives and amine blockers. Biophys. J. 4266-4276.
-
(2008)
Biophys. J
, pp. 4266-4276
-
-
Ma, Q.1
Pavlov, E.2
Britvina, T.3
Zamponi, G.W.4
French, R.J.5
-
9
-
-
0036141825
-
Electrostatic and steric contributions to block of the skeletal muscle sodium channel by μ-conotoxin
-
Hui, K., G. Lipkind, H. A. Fozzard, and R. J. French. 2002. Electrostatic and steric contributions to block of the skeletal muscle sodium channel by μ-conotoxin. J. Gen. Physiol. 119:45-54.
-
(2002)
J. Gen. Physiol
, vol.119
, pp. 45-54
-
-
Hui, K.1
Lipkind, G.2
Fozzard, H.A.3
French, R.J.4
-
10
-
-
11244296111
-
Modeling p-loops domain of sodium channel: Homology with potassium channels and interaction with ligands
-
Tikhonov, D. B., and B. S. Zhorov. 2005. Modeling p-loops domain of sodium channel: homology with potassium channels and interaction with ligands. Biophys. J. 88:184-197.
-
(2005)
Biophys. J
, vol.88
, pp. 184-197
-
-
Tikhonov, D.B.1
Zhorov, B.S.2
-
11
-
-
55749096772
-
Docking orientation of μ-conotoxin GIIIA in the sodium channel outer vestibule
-
Choudhary, G., M. P. Aliste, D. P. Tieleman, R. J. French, and S. C. Dudley, Jr. 2007. Docking orientation of μ-conotoxin GIIIA in the sodium channel outer vestibule. Channels. 1:344-352.
-
(2007)
Channels
, vol.1
, pp. 344-352
-
-
Choudhary, G.1
Aliste, M.P.2
Tieleman, D.P.3
French, R.J.4
Dudley Jr., S.C.5
-
12
-
-
0003422981
-
Boundary Element Method
-
Oxford University Press, Oxford
-
Paris, F., and J. Canas. 1997. Boundary Element Method. Fundamentals and Applications. Oxford University Press, Oxford.
-
(1997)
Fundamentals and Applications
-
-
Paris, F.1
Canas, J.2
-
13
-
-
33751392187
-
Computation of the electrostatic interaction energy between a protein and a charged surface
-
Yoon, B. J., and A. M. Lenhoff. 1992. Computation of the electrostatic interaction energy between a protein and a charged surface. J. Phys. Chem. 96:3130-3134.
-
(1992)
J. Phys. Chem
, vol.96
, pp. 3130-3134
-
-
Yoon, B.J.1
Lenhoff, A.M.2
-
14
-
-
0031237025
-
Calculating aciddissociation constants of proteins using the boundary element method
-
Juffer, A. H., P. Argos, and H. J. Vogel. 1997. Calculating aciddissociation constants of proteins using the boundary element method. J. Phys. Chem. B. 101:7664-7673.
-
(1997)
J. Phys. Chem. B
, vol.101
, pp. 7664-7673
-
-
Juffer, A.H.1
Argos, P.2
Vogel, H.J.3
-
15
-
-
0029862941
-
Energy barrier presented to ions by the vestibule of the biological membrane channel
-
Hoyles, M., S. Kuyucak, and S.-H. Chung. 1996. Energy barrier presented to ions by the vestibule of the biological membrane channel. Biophys. J. 70:1628-1642.
-
(1996)
Biophys. J
, vol.70
, pp. 1628-1642
-
-
Hoyles, M.1
Kuyucak, S.2
Chung, S.-H.3
-
16
-
-
0036151669
-
Conducting-state properties of the KcsA potassium channel from molecular and Brownian dynamics simulations
-
Chung, S. H., T. W. Allen, and S. Kuyucak. 2002. Conducting-state properties of the KcsA potassium channel from molecular and Brownian dynamics simulations. Biophys. J. 82:628-645.
-
(2002)
Biophys. J
, vol.82
, pp. 628-645
-
-
Chung, S.H.1
Allen, T.W.2
Kuyucak, S.3
-
17
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science. 280:69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Cabral, J.M.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
21
-
-
0037488179
-
Conotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel
-
Hui, K., D. McIntyre, and R. J. French. 2003. Conotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel. J. Gen. Physiol. 122:63-79.
-
(2003)
J. Gen. Physiol
, vol.122
, pp. 63-79
-
-
Hui, K.1
McIntyre, D.2
French, R.J.3
-
22
-
-
27844589940
-
Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels
-
Lipkind, G. M., and H. A. Fozzard. 2005. Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels. Mol. Pharmacol. 68:1611-1622.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 1611-1622
-
-
Lipkind, G.M.1
Fozzard, H.A.2
-
23
-
-
34548641160
-
Sodium channels: Ionic model of slow inactivation and state-dependent drug binding
-
Tikhonov, D. B., and B. S. Zhorov. 2007. Sodium channels: ionic model of slow inactivation and state-dependent drug binding. Biophys. J. 93:1557-1570.
-
(2007)
Biophys. J
, vol.93
, pp. 1557-1570
-
-
Tikhonov, D.B.1
Zhorov, B.S.2
-
25
-
-
0028353825
-
Ion permeation, divalent ion block and chemical modifications of single sodium channels: Description by single-occupancy, rate theory models
-
French, R. J., J. F. Worley III, W. F. Wonderlin, A. S. Kularatna, and B. K. Krueger. 1994. Ion permeation, divalent ion block and chemical modifications of single sodium channels: description by single-occupancy, rate theory models. J. Gen. Physiol. 103:447-470.
-
(1994)
J. Gen. Physiol
, vol.103
, pp. 447-470
-
-
French, R.J.1
Worley III, J.F.2
Wonderlin, W.F.3
Kularatna, A.S.4
Krueger, B.K.5
-
26
-
-
0020972776
-
Sodium channel gating: Models, mimics and modifiers
-
French, R. J., and R. Horn. 1983. Sodium channel gating: models, mimics and modifiers. Annu. Rev. Biophys. Bioeng. 12:319-356.
-
(1983)
Annu. Rev. Biophys. Bioeng
, vol.12
, pp. 319-356
-
-
French, R.J.1
Horn, R.2
-
27
-
-
0027968092
-
Internal block by human heart sodium channels by symmetrical tetra-alkylammoniums
-
O'Leary, M. E., and R. Horn. 1994. Internal block by human heart sodium channels by symmetrical tetra-alkylammoniums. J. Gen. Physiol. 104:507-522.
-
(1994)
J. Gen. Physiol
, vol.104
, pp. 507-522
-
-
O'Leary, M.E.1
Horn, R.2
-
28
-
-
0028024516
-
Evidence for a direct interaction between internal tetra- alkylammonium cations and the inactivation gate of cardiac sodium channels
-
O'Leary, M. E., R. G. Kallen, and R. Horn. 1994. Evidence for a direct interaction between internal tetra- alkylammonium cations and the inactivation gate of cardiac sodium channels. J. Gen. Physiol. 104:523-539.
-
(1994)
J. Gen. Physiol
, vol.104
, pp. 523-539
-
-
O'Leary, M.E.1
Kallen, R.G.2
Horn, R.3
-
29
-
-
0013975093
-
+-induced anomalous rectification in squid giant axons
-
+-induced anomalous rectification in squid giant axons. J. Gen. Physiol. 50:491-503.
-
(1966)
J. Gen. Physiol
, vol.50
, pp. 491-503
-
-
Armstrong, C.M.1
-
30
-
-
0015324606
-
The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier
-
Armstrong, C. M., and B. Hille. 1972. The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier. J. Gen. Physiol. 59:388-400.
-
(1972)
J. Gen. Physiol
, vol.59
, pp. 388-400
-
-
Armstrong, C.M.1
Hille, B.2
-
31
-
-
0019419445
-
Blockage of squid axon potassium conductance by internal tetra-n-alkylammonium ions of various sizes
-
French, R. J., and J. J. Shoukimas. 1981. Blockage of squid axon potassium conductance by internal tetra-n-alkylammonium ions of various sizes. Biophys. J. 34:271-291.
-
(1981)
Biophys. J
, vol.34
, pp. 271-291
-
-
French, R.J.1
Shoukimas, J.J.2
-
32
-
-
0026682574
-
Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels
-
Newland, C. F., J. P. Adelman, B. L. Tempel, and W. Almers. 1992. Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels. Neuron. 8:975-982.
-
(1992)
Neuron
, vol.8
, pp. 975-982
-
-
Newland, C.F.1
Adelman, J.P.2
Tempel, B.L.3
Almers, W.4
-
34
-
-
0021284545
-
A non-selective cation conductance in frog muscle blocked by micromolar external calcium ions
-
Almers, W., E. W. McCleskey, and P. T. Palade. 1984. A non-selective cation conductance in frog muscle blocked by micromolar external calcium ions. J. Physiol. 353:565-583.
-
(1984)
J. Physiol
, vol.353
, pp. 565-583
-
-
Almers, W.1
McCleskey, E.W.2
Palade, P.T.3
-
35
-
-
0021280815
-
Mechanism of ion permeation through calcium channels
-
Hess, P., and R. W. Tsien. 1984. Mechanism of ion permeation through calcium channels. Nature. 309:453-456.
-
(1984)
Nature
, vol.309
, pp. 453-456
-
-
Hess, P.1
Tsien, R.W.2
-
38
-
-
0034043402
-
Interaction between quaternary ammonium ions in the pore of potassium channels. Evidence against an electrostatic repulsion mechanism
-
Thompson, J., and T. Begenisich. 2000. Interaction between quaternary ammonium ions in the pore of potassium channels. Evidence against an electrostatic repulsion mechanism. J. Gen. Physiol. 115:769-782.
-
(2000)
J. Gen. Physiol
, vol.115
, pp. 769-782
-
-
Thompson, J.1
Begenisich, T.2
-
39
-
-
0027140475
-
Dissecting lidocaine action: Diethylamine and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle
-
Zamponi, G. W., and R. J. French. 1993. Dissecting lidocaine action: diethylamine and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle. Biophys. J. 65:2335-2347.
-
(1993)
Biophys. J
, vol.65
, pp. 2335-2347
-
-
Zamponi, G.W.1
French, R.J.2
-
40
-
-
0032921414
-
+ channel. Equilibrium and kinetic basis of negatively coupled ligand interactions
-
+ channel. Equilibrium and kinetic basis of negatively coupled ligand interactions. J. Gen. Physiol. 113:295-320.
-
(1999)
J. Gen. Physiol
, vol.113
, pp. 295-320
-
-
Favre, I.1
Moczydlowski, E.2
-
41
-
-
0021222501
-
+ channels of bovine chromaffin cells
-
+ channels of bovine chromaffin cells. J. Gen. Physiol. 84:157-186.
-
(1984)
J. Gen. Physiol
, vol.84
, pp. 157-186
-
-
Yellen, G.1
-
42
-
-
0021137261
-
+ channels by external cations
-
+ channels by external cations. J. Gen. Physiol. 84:187-199.
-
(1984)
J. Gen. Physiol
, vol.84
, pp. 187-199
-
-
Yellen, G.1
-
43
-
-
0022470774
-
2+. Voltage and concentration dependence of calcium entry into the pore
-
2+. Voltage and concentration dependence of calcium entry into the pore. J. Gen. Physiol. 88:321-347.
-
(1986)
J. Gen. Physiol
, vol.88
, pp. 321-347
-
-
Lansman, J.B.1
Hess, P.2
Tsien, R.W.3
-
44
-
-
0021878082
-
An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions
-
French, R. J., and J. J. Shoukimas. 1985. An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions. J. Gen. Physiol. 85:669-698.
-
(1985)
J. Gen. Physiol
, vol.85
, pp. 669-698
-
-
French, R.J.1
Shoukimas, J.J.2
-
45
-
-
0035822048
-
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
-
Zhou, M., J. H. Morais-Cabral, S. Mann, and R. MacKinnon. 2001. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature. 411:657-661.
-
(2001)
Nature
, vol.411
, pp. 657-661
-
-
Zhou, M.1
Morais-Cabral, J.H.2
Mann, S.3
MacKinnon, R.4
-
46
-
-
33845663257
-
+ channel by tetrabutylammonium: Insights from x-ray crystallography, electrophysiology and replica-exchange molecular dynamics simulations
-
+ channel by tetrabutylammonium: insights from x-ray crystallography, electrophysiology and replica-exchange molecular dynamics simulations. J. Mol. Biol. 365:649-662.
-
(2007)
J. Mol. Biol
, vol.365
, pp. 649-662
-
-
Faraldo-Gomez, J.D.1
Kutluay, E.2
Jogini, V.3
Zhao, Y.4
Heginbotham, L.5
Roux, B.6
-
50
-
-
0027279027
-
+ channel from toad skeletal muscle
-
+ channel from toad skeletal muscle. Biophys. J. 64:1038-1050.
-
(1993)
Biophys. J
, vol.64
, pp. 1038-1050
-
-
Naranjo, D.1
Latorre, R.2
-
51
-
-
33750532138
-
Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine
-
Tikhonov, D. B., I. Bruhova, and B. S. Zhorov. 2006. Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine. FEBS Lett. 580:6027-6032.
-
(2006)
FEBS Lett
, vol.580
, pp. 6027-6032
-
-
Tikhonov, D.B.1
Bruhova, I.2
Zhorov, B.S.3
-
52
-
-
33749237986
-
Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding
-
Scheib, H., I. McLay, N. Guex, J. J. Clare, F. E. Blaney, T. J. Dale, S. N. Tate, and G. M. Robertson. 2006. Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding. J. Mol. Model. 12:813-822.
-
(2006)
J. Mol. Model
, vol.12
, pp. 813-822
-
-
Scheib, H.1
McLay, I.2
Guex, N.3
Clare, J.J.4
Blaney, F.E.5
Dale, T.J.6
Tate, S.N.7
Robertson, G.M.8
-
54
-
-
0026657359
-
Action of derivatives of μ-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates
-
Becker, S., E. Prusak-Sochaczewski, G. Zamponi, A. G. Beck-Sickinger, R. D. Gordon, and R. J. French. 1992. Action of derivatives of μ-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates. Biochemistry. 31:8229-8238.
-
(1992)
Biochemistry
, vol.31
, pp. 8229-8238
-
-
Becker, S.1
Prusak-Sochaczewski, E.2
Zamponi, G.3
Beck-Sickinger, A.G.4
Gordon, R.D.5
French, R.J.6
-
55
-
-
61349091827
-
An attempt to determine the orientation of μ-conotoxin binding to sodium channels by mapping the contributions of individual residues to the voltage dependence of block
-
McArthur, J. R., and R. J. French. 2007. An attempt to determine the orientation of μ-conotoxin binding to sodium channels by mapping the contributions of individual residues to the voltage dependence of block. Biophys. J. 92(Suppl.):178a.
-
(2007)
Biophys. J
, vol.92
, Issue.SUPPL.
-
-
McArthur, J.R.1
French, R.J.2
-
56
-
-
34249674070
-
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels
-
McNulty, M. M., G. B. Edgerton, R. D. Shah, D. A. Hanck, H. A. Fozzard, and G. M. Lipkind. 2007. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. J. Physiol. Lond. 581:741-755.
-
(2007)
J. Physiol. Lond
, vol.581
, pp. 741-755
-
-
McNulty, M.M.1
Edgerton, G.B.2
Shah, R.D.3
Hanck, D.A.4
Fozzard, H.A.5
Lipkind, G.M.6
-
57
-
-
33751517446
-
A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels
-
Ahern, C. A., A. L. Eastwood, H. A. Lester, D. A. Dougherty, and R. Horn. 2006. A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels. J. Gen. Physiol. 128:649-657.
-
(2006)
J. Gen. Physiol
, vol.128
, pp. 649-657
-
-
Ahern, C.A.1
Eastwood, A.L.2
Lester, H.A.3
Dougherty, D.A.4
Horn, R.5
-
58
-
-
37849001772
-
Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels
-
Ahern, C. A., A. L. Eastwood, D. A. Dougherty, and R. Horn. 2008. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circ. Res. 102:86-94.
-
(2008)
Circ. Res
, vol.102
, pp. 86-94
-
-
Ahern, C.A.1
Eastwood, A.L.2
Dougherty, D.A.3
Horn, R.4
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