-
1
-
-
0031706572
-
Population pharmacokinetics of cyclosporine: Influence of covariables and assessment of cyclospor-ine absorption in kidney, lung, heart and heart+lung transplanted patients
-
Kyhl LE, Rasmussen SN, Aarons L, et al. Population pharmacokinetics of cyclosporine: Influence of covariables and assessment of cyclospor-ine absorption in kidney, lung, heart and heart+lung transplanted patients. Transplant Proc 1998; 30: 1680.
-
(1998)
Transplant Proc
, vol.30
, pp. 1680
-
-
Kyhl, L.E.1
Rasmussen, S.N.2
Aarons, L.3
-
3
-
-
0036766650
-
Adequate early cyclosporin exposure is critical to prevent renal allograft rejection: Patients monitored by absorption profiling
-
Clase CM, Mahalati K, Kiberd BA, et al. Adequate early cyclosporin exposure is critical to prevent renal allograft rejection: Patients monitored by absorption profiling. Am J Transplant 2002; 2: 789.
-
(2002)
Am J Transplant
, vol.2
, pp. 789
-
-
Clase, C.M.1
Mahalati, K.2
Kiberd, B.A.3
-
4
-
-
0034852733
-
Low tacrolimus concentrations and increased risk of early acute rejection in adult renal transplantation
-
Staatz C, Taylor P, Tett S. Low tacrolimus concentrations and increased risk of early acute rejection in adult renal transplantation. Nephrol Dial Transplant 2001; 16: 1905.
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 1905
-
-
Staatz, C.1
Taylor, P.2
Tett, S.3
-
6
-
-
17844385047
-
Metabolism- based drug- drug interactions: Wshat determines individual variability in cytochrome P450 induction?
-
Tang C, Lin JH, Lu AY. Metabolism- based drug- drug interactions: Wshat determines individual variability in cytochrome P450 induction? Drug Metab Dispos 2005; 33: 603.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 603
-
-
Tang, C.1
Lin, J.H.2
Lu, A.Y.3
-
7
-
-
0035238531
-
Cyclosporin: An updated review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (neoral) 1 in organ transplantation
-
Dunn CJ, Waqstaff AJ, Perry CM, et al. Cyclosporin: An updated review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (neoral) 1 in organ transplantation. Drugs 2001; 61: 1957.
-
(2001)
Drugs
, vol.61
, pp. 1957
-
-
Dunn, C.J.1
Waqstaff, A.J.2
Perry, C.M.3
-
9
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE, Relling MV. Pharmacogenomics: Translating functional genomics into rational therapeutics. Science 1999; 286: 487.
-
(1999)
Science
, vol.286
, pp. 487
-
-
Evans, W.E.1
Relling, M.V.2
-
10
-
-
0024512139
-
Clinical pharmacokinetics of cyclosporin
-
McMillan MA. Clinical pharmacokinetics of cyclosporin. Pharmacol Ther 1989; 42: 135.
-
(1989)
Pharmacol Ther
, vol.42
, pp. 135
-
-
McMillan, M.A.1
-
11
-
-
0026681640
-
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as a major enzymes responsible for its metabolism
-
Vincent SH, Karanam BV, Painter SK, et al. In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as a major enzymes responsible for its metabolism. Arch Biochem Biophhys 1992; 294: 454.
-
(1992)
Arch Biochem Biophhys
, vol.294
, pp. 454
-
-
Vincent, S.H.1
Karanam, B.V.2
Painter, S.K.3
-
12
-
-
33749267293
-
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs
-
Cascorbi I. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol Ther 2006; 112: 457.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 457
-
-
Cascorbi, I.1
-
13
-
-
0029560982
-
Metabolism of the immunosuppressant tacrolimus in the small intestine: Cytochrome P450, drug interactions, and interindividual variability
-
Lampen A, Christians U, Guengerich FP, et al. Metabolism of the immunosuppressant tacrolimus in the small intestine: Cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos 1995; 23: 1315.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 1315
-
-
Lampen, A.1
Christians, U.2
Guengerich, F.P.3
-
14
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97: 3473.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
-
15
-
-
0347359079
-
Increased transcriptional activity of the CYP3A4*1B promoter variant
-
Amirimani B, Ning B, Deitz AC, et al. Increased transcriptional activity of the CYP3A4*1B promoter variant. Environ Mol Mutagen 2003; 42: 299.
-
(2003)
Environ Mol Mutagen
, vol.42
, pp. 299
-
-
Amirimani, B.1
Ning, B.2
Deitz, A.C.3
-
16
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P, Zhang J, Lin Y, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001; 27: 383.
-
(2001)
Nat Genet
, vol.27
, pp. 383
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
-
17
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimchi-Sarfaty C, Oh JM, Kim IW, et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007; 315: 525.
-
(2007)
Science
, vol.315
, pp. 525
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
-
18
-
-
12144286933
-
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
-
Haufroid V, Mourad M, van Kerckhove V, et al. The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics 2004; 14: 147.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 147
-
-
Haufroid, V.1
Mourad, M.2
van Kerckhove, V.3
-
19
-
-
7044272257
-
Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients
-
Tsuchiya N, Satoh S, Tada H, et al. Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients. Transplantation 2004; 78: 1182.
-
(2004)
Transplantation
, vol.78
, pp. 1182
-
-
Tsuchiya, N.1
Satoh, S.2
Tada, H.3
-
20
-
-
27644467774
-
Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids
-
Mourad M, Mourad G, Wallemacq P, et al. Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. Transplantation 2005; 80: 977.
-
(2005)
Transplantation
, vol.80
, pp. 977
-
-
Mourad, M.1
Mourad, G.2
Wallemacq, P.3
-
21
-
-
2942588886
-
The influence of pharmacoge-netics on the time to achieve target tacrolimus concentrations after kidney transplantation
-
MacPhee IA, Fredericks S, Tai T, et al. The influence of pharmacoge-netics on the time to achieve target tacrolimus concentrations after kidney transplantation. Am J Transplant 2004; 4: 843.
-
(2004)
Am J Transplant
, vol.4
, pp. 843
-
-
MacPhee, I.A.1
Fredericks, S.2
Tai, T.3
-
22
-
-
14044278166
-
Tacrolimus pharmaco-genetics: The CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians
-
MacPhee IA, Fredericks S, Mohamed M, et al. Tacrolimus pharmaco-genetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians. Transplantation 2005; 79: 499.
-
(2005)
Transplantation
, vol.79
, pp. 499
-
-
MacPhee, I.A.1
Fredericks, S.2
Mohamed, M.3
-
23
-
-
34248996167
-
Polymorphisms of multidrug resistance gene (MDR1) and cyclosporine absorption in de novo renal transplant patients
-
Foote CJ, Greer W, Kiberd B, et al. Polymorphisms of multidrug resistance gene (MDR1) and cyclosporine absorption in de novo renal transplant patients. Transplantation 2007; 83: 1380.
-
(2007)
Transplantation
, vol.83
, pp. 1380
-
-
Foote, C.J.1
Greer, W.2
Kiberd, B.3
-
24
-
-
33845955117
-
The MDR1/ABCB1 gene, a high-impact risk factor for cardiac transplant rejection
-
Barnard JB, Richardson S, Sheldon S, et al. The MDR1/ABCB1 gene, a high-impact risk factor for cardiac transplant rejection. Transplantation 2006; 82: 1677.
-
(2006)
Transplantation
, vol.82
, pp. 1677
-
-
Barnard, J.B.1
Richardson, S.2
Sheldon, S.3
-
25
-
-
30344450824
-
Intestinal MDR1/ABCB1 level at surgery as a risk factor of acute cellular rejection in living-donor liver transplant patients
-
Masuda S, Goto M, Fukatsu S, et al. Intestinal MDR1/ABCB1 level at surgery as a risk factor of acute cellular rejection in living-donor liver transplant patients. Clin Pharmacol Ther 2006; 79: 90.
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 90
-
-
Masuda, S.1
Goto, M.2
Fukatsu, S.3
-
26
-
-
33748710224
-
Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements
-
Fredericks S, Moreton M, Reboux S, et al. Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements. Transplantation 2006; 82: 705.
-
(2006)
Transplantation
, vol.82
, pp. 705
-
-
Fredericks, S.1
Moreton, M.2
Reboux, S.3
-
27
-
-
9144253194
-
MDR1 haplotypes derived from exons 21 and26 donot affect the steady-state pharmacokinetics oftacrolimus in renal transplant patients
-
Mai I, Perloff ES, Bauer S, et al. MDR1 haplotypes derived from exons 21 and26 donot affect the steady-state pharmacokinetics oftacrolimus in renal transplant patients. Br J Clin Pharmacol 2004; 58: 548.
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 548
-
-
Mai, I.1
Perloff, E.S.2
Bauer, S.3
-
28
-
-
26244444318
-
What makes a good genetic association study?
-
Hattersley AT, McCarthy MI. What makes a good genetic association study? Lancet 2005; 366: 1315.
-
(2005)
Lancet
, vol.366
, pp. 1315
-
-
Hattersley, A.T.1
McCarthy, M.I.2
-
29
-
-
0032910625
-
The Banff 97 working classification of renal allograft pathology
-
Racusen LC, Solez K, Colvin RB, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713.
-
(1999)
Kidney Int
, vol.55
, pp. 713
-
-
Racusen, L.C.1
Solez, K.2
Colvin, R.B.3
-
30
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69: 169.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
-
31
-
-
79959503826
-
-
The International HapMap Project
-
The International HapMap Project. Nature 2003; 426: 789.
-
(2003)
Nature
, vol.426
, pp. 789
-
-
-
32
-
-
66149166630
-
-
Excoffier L, Laval G, Schneider S. Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evol Bioinform Online 2005; 1: 47
-
Excoffier L, Laval G, Schneider S. Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evol Bioinform Online 2005; 1: 47.
-
-
-
-
33
-
-
0030131165
-
Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm
-
Slatkin M, Excoffier L. Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm. Heredity 1996; 76 (Pt 4): 377.
-
(1996)
Heredity
, vol.76
, Issue.PART 4
, pp. 377
-
-
Slatkin, M.1
Excoffier, L.2
-
34
-
-
0038304548
-
Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
-
Anglicheau D, Verstuyft C, Laurent- Puiq P, et al. Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J Am Soc Nephrol 2003; 14: 1955.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1955
-
-
Anglicheau, D.1
Verstuyft, C.2
Laurent- Puiq, P.3
-
35
-
-
1542515172
-
From genotypes to haplotypes in hepatobiliary diseases: One plus one equals (sometimes) more than two
-
Wasmuth HE, Matern S, Lammert F. From genotypes to haplotypes in hepatobiliary diseases: one plus one equals (sometimes) more than two. Hepatology 2004; 39: 604.
-
(2004)
Hepatology
, vol.39
, pp. 604
-
-
Wasmuth, H.E.1
Matern, S.2
Lammert, F.3
-
36
-
-
1142299591
-
Haplotype mapping of the bron-chiolitis susceptibility locus near IL8
-
Hull J, Rowlands K, Lockhart E, et al. Haplotype mapping of the bron-chiolitis susceptibility locus near IL8. Hum Genet 2004; 114: 272.
-
(2004)
Hum Genet
, vol.114
, pp. 272
-
-
Hull, J.1
Rowlands, K.2
Lockhart, E.3
-
37
-
-
33947722588
-
Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements
-
Fredericks S, Jorga A, MacPhee IA, et al. Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements. Clin Transplant 2007; 21: 252.
-
(2007)
Clin Transplant
, vol.21
, pp. 252
-
-
Fredericks, S.1
Jorga, A.2
MacPhee, I.A.3
-
38
-
-
11144358432
-
CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation
-
Anglicheau D, Thervet E, Etienne I, et al. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation. Clin Pharmacol Ther 2004; 75: 422.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 422
-
-
Anglicheau, D.1
Thervet, E.2
Etienne, I.3
-
40
-
-
0035135523
-
A candidate prostate cancer susceptibility gene at chromosome 17p
-
Tavtigian SV, Simard J, Teng DH, et al. A candidate prostate cancer susceptibility gene at chromosome 17p. Nat Genet 2001; 27: 134.
-
(2001)
Nat Genet
, vol.27
, pp. 134
-
-
Tavtigian, S.V.1
Simard, J.2
Teng, D.H.3
-
41
-
-
33646681672
-
The influence of CYP3A gene polymorphisms on cyclosporine dose requirement in renal allograft recipients
-
Eng HS, Mohamed Z, Calne R, et al. The influence of CYP3A gene polymorphisms on cyclosporine dose requirement in renal allograft recipients. Kidney Int 2006; 69: 1858.
-
(2006)
Kidney Int
, vol.69
, pp. 1858
-
-
Eng, H.S.1
Mohamed, Z.2
Calne, R.3
-
43
-
-
33749013001
-
Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases
-
Ioannidis JP, Trikalinis TA, Khoury MJ. Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol 2006; 167: 609.
-
(2006)
Am J Epidemiol
, vol.167
, pp. 609
-
-
Ioannidis, J.P.1
Trikalinis, T.A.2
Khoury, M.J.3
|