Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites

Journal of Biological Chemistry

Volumn 283, Issue 51, 2008, Pages 35899-35907

  Madrid, Dennis C ^a   Ting, Li Min ^a   Waller, Karena L ^a,b   Schramm, Vern L ^a   Kim, Kami ^a,c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MONASH UNIVERSITY   (Australia)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG INTERACTIONS; ENZYMES; PHOSPHORYLATION; TARGETS;

ADENOSINE DEAMINASE; GENE DISRUPTIONS; GROWTH DEFECTS; IN VITRO; LYSATES; MALARIA PARASITES; PHYSIOLOGICAL CONCENTRATIONS; PLASMODIUM FALCIPARUM; POTENTIAL DRUGS; PURINE NUCLEOSIDE PHOSPHORYLASES; SALVAGE ENZYMES; TRANSGENIC; TRANSITION STATE ANALOGUE INHIBITORS; TRANSITION STATES;

ENZYME ACTIVITY;

ADENOSINE DEAMINASE; HYPOXANTHINE; PURINE DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE; RNA;

ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DISRUPTION; GENE TARGETING; HUMAN; HUMAN CELL; MALARIA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; WESTERN BLOTTING;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ENZYME INHIBITORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PURINE-NUCLEOSIDE PHOSPHORYLASE; PURINES; PYRIMIDINONES; PYRROLIDINES;

PLASMODIUM FALCIPARUM;

EID: 58149093352     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807218200     Document Type: Article

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