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Volumn 19, Issue 12, 2008, Pages 2527-2534

Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2

Author keywords

[No Author keywords available]

Indexed keywords

ALEXA FLUOR488; ALLOPHYCOCYANIN; ANTIBODY CONJUGATE; CD20 ANTIGEN; CYSTEINE; CYSTEINE DIABODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUORESCENT DYE; PHYCOERYTHRIN; THIOL; UNCLASSIFIED DRUG;

EID: 58149085521     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800113v     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 27144449009 scopus 로고    scopus 로고
    • Monoclonal antibody therapy of cancer
    • Adams, G. P., and Weiner, L. M. (2005) Monoclonal antibody therapy of cancer. Nat. Biotechnol. 23, 1147-57.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1147-1157
    • Adams, G.P.1    Weiner, L.M.2
  • 2
    • 13944266719 scopus 로고    scopus 로고
    • Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody
    • Robinson, M. K., Doss, M., Shaller, C., Narayanan, D., Marks, J. D., Adler, L. P., Gonzalez Trotter, D. E., and Adams, G. P. (2005) Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody. Cancer Res. 65, 1471-8.
    • (2005) Cancer Res , vol.65 , pp. 1471-1478
    • Robinson, M.K.1    Doss, M.2    Shaller, C.3    Narayanan, D.4    Marks, J.D.5    Adler, L.P.6    Gonzalez Trotter, D.E.7    Adams, G.P.8
  • 3
    • 34047193860 scopus 로고    scopus 로고
    • PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody
    • Cai, W., Olafsen, T., Zhang, X., Cao, Q., Gambhir, S. S., Williams, L. E., Wu, A. M., and Chen, X. (2007) PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody. J. Nucl. Med. 48, 304-10.
    • (2007) J. Nucl. Med , vol.48 , pp. 304-310
    • Cai, W.1    Olafsen, T.2    Zhang, X.3    Cao, Q.4    Gambhir, S.S.5    Williams, L.E.6    Wu, A.M.7    Chen, X.8
  • 5
    • 33746836894 scopus 로고    scopus 로고
    • Targeted therapy of cancer: New prospects for antibodies and immunoconjugates
    • Sharkey, R. M., and Goldenberg, D. M. (2006) Targeted therapy of cancer: new prospects for antibodies and immunoconjugates. CA Cancer J. Clin. 56, 226-43.
    • (2006) CA Cancer J. Clin , vol.56 , pp. 226-243
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 6
    • 27144550160 scopus 로고    scopus 로고
    • Arming antibodies: Prospects and challenges for immunoconjugates
    • Wu, A. M., and Senter, P. D. (2005) Arming antibodies: prospects and challenges for immunoconjugates. Nat. Biotechnol. 23, 1137-46.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1137-1146
    • Wu, A.M.1    Senter, P.D.2
  • 7
    • 0033791994 scopus 로고    scopus 로고
    • Designer genes: Recombinant antibody fragments for biological imaging
    • Wu, A. M., and Yazaki, P. J. (2000) Designer genes: recombinant antibody fragments for biological imaging. Q. J. Nucl. Med. 44, 268-83.
    • (2000) Q. J. Nucl. Med , vol.44 , pp. 268-283
    • Wu, A.M.1    Yazaki, P.J.2
  • 8
    • 34248655131 scopus 로고    scopus 로고
    • Tunable pharmacokinetics: Modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment
    • Olafsen, T., Kenanova, V. E., and Wu, A. M. (2006) Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment. Nat. Protoc. 1, 2048-60.
    • (2006) Nat. Protoc , vol.1 , pp. 2048-2060
    • Olafsen, T.1    Kenanova, V.E.2    Wu, A.M.3
  • 9
    • 37249071981 scopus 로고    scopus 로고
    • Development of anti-MUC1 di-scFvs for molecular targeting of epithelial cancers, such as breast and prostate cancers
    • Albrecht, H., Denardo, G. L., and Denardo, S. J. (2007) Development of anti-MUC1 di-scFvs for molecular targeting of epithelial cancers, such as breast and prostate cancers. Q. J. Nucl. Med. Mol. Imaging 51, 304-13.
    • (2007) Q. J. Nucl. Med. Mol. Imaging , vol.51 , pp. 304-313
    • Albrecht, H.1    Denardo, G.L.2    Denardo, S.J.3
  • 11
    • 38349025843 scopus 로고    scopus 로고
    • Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan
    • Uchino, J., Takayama, K., Harada, A., Sone, T., Harada, T., Curiel, D. T., Kuroki, M., and Nakanishi, Y. (2008) Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan. Cancer Gene Ther. 15, 94-100.
    • (2008) Cancer Gene Ther , vol.15 , pp. 94-100
    • Uchino, J.1    Takayama, K.2    Harada, A.3    Sone, T.4    Harada, T.5    Curiel, D.T.6    Kuroki, M.7    Nakanishi, Y.8
  • 12
    • 0034830739 scopus 로고    scopus 로고
    • Dimeric and trimeric antibodies: High avidity scFvs for cancer targeting
    • Kortt, A. A., Dolezal, O., Power, B. E., and Hudson, P. J. (2001) Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting. Biomol. Eng. 18, 95-108.
    • (2001) Biomol. Eng , vol.18 , pp. 95-108
    • Kortt, A.A.1    Dolezal, O.2    Power, B.E.3    Hudson, P.J.4
  • 14
    • 0036223858 scopus 로고    scopus 로고
    • Radioiodination of monoclonal antibodies, proteins and peptides for diagnosis and therapy. A review of standardized, reliable and safe procedures for clinical grade levels kBq to GBq in the Gottingen/Marburg experience
    • Behr, T. M., Gotthardt, M., Becker, W., and Behe, M. (2002) Radioiodination of monoclonal antibodies, proteins and peptides for diagnosis and therapy. A review of standardized, reliable and safe procedures for clinical grade levels kBq to GBq in the Gottingen/Marburg experience. Nuklearmedizin 41, 71-9.
    • (2002) Nuklearmedizin , vol.41 , pp. 71-79
    • Behr, T.M.1    Gotthardt, M.2    Becker, W.3    Behe, M.4
  • 15
    • 0029146320 scopus 로고
    • Impact of the high tyrosine fraction in complementarity determining regions: Measured and predicted effects of radioiodination on IgG immunoreactivity
    • Nikula, T. K., Bocchia, M., Curcio, M. J., Sgouros, G., Ma, Y., Finn, R. D., and Scheinberg, D. A. (1995) Impact of the high tyrosine fraction in complementarity determining regions: measured and predicted effects of radioiodination on IgG immunoreactivity. Mol. Immunol. 32, 865-72.
    • (1995) Mol. Immunol , vol.32 , pp. 865-872
    • Nikula, T.K.1    Bocchia, M.2    Curcio, M.J.3    Sgouros, G.4    Ma, Y.5    Finn, R.D.6    Scheinberg, D.A.7
  • 16
    • 0029077481 scopus 로고
    • Engineering disulfide-linked single-chain Fv dimers [(sFv′)2] with improved solution and targeting properties: Anti-digoxin 26-10 (sFv′)2 and anti-c-erbB-2 741F8 (sFv′)2 made by protein folding and bonded through C-terminal cysteinyl peptides
    • McCartney, J. E., Tai, M. S., Hudziak, R. M., Adams, G. P., Weiner, L. M., Jin, D., Stafford, W. F., 3rd., Liu, S., Bookman, M. A., and Laminet, A. A. (1995) Engineering disulfide-linked single-chain Fv dimers [(sFv′)2] with improved solution and targeting properties: anti-digoxin 26-10 (sFv′)2 and anti-c-erbB-2 741F8 (sFv′)2 made by protein folding and bonded through C-terminal cysteinyl peptides. Protein Eng. 8, 301-14.
    • (1995) Protein Eng , vol.8 , pp. 301-314
    • McCartney, J.E.1    Tai, M.S.2    Hudziak, R.M.3    Adams, G.P.4    Weiner, L.M.5    Jin, D.6    Stafford 3rd, W.F.7    Liu, S.8    Bookman, M.A.9    Laminet, A.A.10
  • 18
    • 0029118828 scopus 로고
    • Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: Technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide
    • George, A. J., Jamar, F., Tai, M. S., Heelan, B. T., Adams, G. P., McCartney, J. E., Houston, L. L., Weiner, L. M., Oppermann, H., and Peters, A. M. (1995) Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide. Proc. Natl. Acad. Sci. U.S.A. 92, 8358-62.
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 8358-8362
    • George, A.J.1    Jamar, F.2    Tai, M.S.3    Heelan, B.T.4    Adams, G.P.5    McCartney, J.E.6    Houston, L.L.7    Weiner, L.M.8    Oppermann, H.9    Peters, A.M.10
  • 21
    • 38949108975 scopus 로고    scopus 로고
    • Novel single-chain Fv′ formats for the generation of immunoliposomes by site-directed coupling
    • Messerschmidt, S. K., Kolbe, A., Muller, D., Knoll, M., Pleiss, J., and Kontermann, R. E. (2008) Novel single-chain Fv′ formats for the generation of immunoliposomes by site-directed coupling. Bioconjugate Chem. 19, 362-9.
    • (2008) Bioconjugate Chem , vol.19 , pp. 362-369
    • Messerschmidt, S.K.1    Kolbe, A.2    Muller, D.3    Knoll, M.4    Pleiss, J.5    Kontermann, R.E.6
  • 22
    • 0037436345 scopus 로고    scopus 로고
    • The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: Implications for diabody flexibility
    • Carmichael, J. A., Power, B. E., Garrett, T. P., Yazaki, P. J., Shively, J. E., Raubischek, A. A., Wu, A. M., and Hudson, P. J. (2003) The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility. J. Mol. Biol. 326, 341-51.
    • (2003) J. Mol. Biol , vol.326 , pp. 341-351
    • Carmichael, J.A.1    Power, B.E.2    Garrett, T.P.3    Yazaki, P.J.4    Shively, J.E.5    Raubischek, A.A.6    Wu, A.M.7    Hudson, P.J.8
  • 24
    • 14744283551 scopus 로고
    • High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selection marker
    • Bebbington, C., Renner, G., Thomson, S., King, D., Abrams, D., and Yarranton, G. T. (1992) High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selection marker. Biotechnology 10, 169-175.
    • (1992) Biotechnology , vol.10 , pp. 169-175
    • Bebbington, C.1    Renner, G.2    Thomson, S.3    King, D.4    Abrams, D.5    Yarranton, G.T.6
  • 25
    • 0035400469 scopus 로고    scopus 로고
    • Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications
    • Yazaki, P. J., Shively, L., Clark, C., Cheung, C. W., Le, W., Szpikowska, B., Shively, J. E., Raubitschek, A. A., and Wu, A. M. (2001) Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications. J. Immunol. Methods 253, 195-208.
    • (2001) J. Immunol. Methods , vol.253 , pp. 195-208
    • Yazaki, P.J.1    Shively, L.2    Clark, C.3    Cheung, C.W.4    Le, W.5    Szpikowska, B.6    Shively, J.E.7    Raubitschek, A.A.8    Wu, A.M.9
  • 29
    • 36749036711 scopus 로고    scopus 로고
    • In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies
    • Barrett, T., Koyama, Y., Hama, Y., Ravizzini, G., Shin, I. S., Jang, B. S., Paik, C. H., Urano, Y., Choyke, P. L., and Kobayashi, H. (2007) In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin. Cancer Res. 13, 6639-48.
    • (2007) Clin. Cancer Res , vol.13 , pp. 6639-6648
    • Barrett, T.1    Koyama, Y.2    Hama, Y.3    Ravizzini, G.4    Shin, I.S.5    Jang, B.S.6    Paik, C.H.7    Urano, Y.8    Choyke, P.L.9    Kobayashi, H.10
  • 30
    • 34249821046 scopus 로고    scopus 로고
    • Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu
    • Koyama, Y., Hama, Y., Urano, Y., Nguyen, D. M., Choyke, P. L., and Kobayashi, H. (2007) Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin. Cancer Res. 13, 2936-45.
    • (2007) Clin. Cancer Res , vol.13 , pp. 2936-2945
    • Koyama, Y.1    Hama, Y.2    Urano, Y.3    Nguyen, D.M.4    Choyke, P.L.5    Kobayashi, H.6
  • 31
    • 12344336363 scopus 로고    scopus 로고
    • Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals
    • Natarajan, A., Xiong, C. Y., Albrecht, H., DeNardo, G. L., and DeNardo, S. J. (2005) Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals. Bioconjugate Chem. 16, 113-21.
    • (2005) Bioconjugate Chem , vol.16 , pp. 113-121
    • Natarajan, A.1    Xiong, C.Y.2    Albrecht, H.3    DeNardo, G.L.4    DeNardo, S.J.5
  • 32
    • 0345504113 scopus 로고    scopus 로고
    • Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds
    • Lee, L. S., Conover, C., Shi, C., Whitlow, M., and Filpula, D. (1999) Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds. Bioconjugate Chem. 10, 973-81.
    • (1999) Bioconjugate Chem , vol.10 , pp. 973-981
    • Lee, L.S.1    Conover, C.2    Shi, C.3    Whitlow, M.4    Filpula, D.5
  • 33
    • 33748763812 scopus 로고    scopus 로고
    • Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors
    • Venisnik, K. M., Olafsen, T., Loening, A. M., Iyer, M., Gambhir, S. S., and Wu, A. M. (2006) Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors. Protein Eng. Des. Sel. 19, 453-60.
    • (2006) Protein Eng. Des. Sel , vol.19 , pp. 453-460
    • Venisnik, K.M.1    Olafsen, T.2    Loening, A.M.3    Iyer, M.4    Gambhir, S.S.5    Wu, A.M.6
  • 34
    • 34548155475 scopus 로고    scopus 로고
    • Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imaging
    • Venisnik, K. M., Olafsen, T., Gambhir, S. S., and Wu, A. M. (2007) Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imaging. Mol. Imaging Biol. 9, 267-77.
    • (2007) Mol. Imaging Biol , vol.9 , pp. 267-277
    • Venisnik, K.M.1    Olafsen, T.2    Gambhir, S.S.3    Wu, A.M.4
  • 37
    • 23844531202 scopus 로고    scopus 로고
    • Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction
    • Kam, N. W., O'Connell, M., Wisdom, J. A., and Dai, H. (2005) Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc. Natl. Acad. Sci. U.S.A. 102, 11600-5.
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 11600-11605
    • Kam, N.W.1    O'Connell, M.2    Wisdom, J.A.3    Dai, H.4
  • 38
    • 27144513329 scopus 로고    scopus 로고
    • Multiplexed electrical detection of cancer markers with nanowire sensor arrays
    • Zheng, G., Patolsky, F., Cui, Y., Wang, W. U., and Lieber, C. M. (2005) Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat. Biotechnol. 23, 1294-301.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1294-1301
    • Zheng, G.1    Patolsky, F.2    Cui, Y.3    Wang, W.U.4    Lieber, C.M.5
  • 39
    • 29544446769 scopus 로고    scopus 로고
    • Carbon nanotube transistors for biosensing applications
    • Gruner, G. (2006) Carbon nanotube transistors for biosensing applications. Anal. Bioanal. Chem. 384, 322-35.
    • (2006) Anal. Bioanal. Chem , vol.384 , pp. 322-335
    • Gruner, G.1


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