Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors

Protein Engineering, Design and Selection

Volumn 19, Issue 10, 2006, Pages 453-460

  Venisnik, Katy M ^a   Olafsen, Tove ^a   Loening, Andreas M ^b,c   Iyer, Meera ^a,b   Gambhir, Sanjiv S ^b,c   Wu, Anna M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c Stanford University   (United States)

Author keywords

Bioluminescence; Carcinoembryonic antigen; Engineered antibodies; Nude mouse xenograft models; Renilla luciferase

Indexed keywords

CARCINOEMBRYONIC ANTIGENS; ENGINEERED ANTIBODIES; NUDE MOUSE XENOGRAFT MODELS; RENILLA LUCIFERASE;

ANTIBODIES; ANTIGENS; BIOLUMINESCENCE; IMAGING SYSTEMS; TUMORS;

PROTEINS;

ANTIBODY; CARCINOEMBRYONIC ANTIGEN; CELL SURFACE RECEPTOR; ENZYME VARIANT; HYBRID PROTEIN; IODINE 124; LUCIFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY ENGINEERING; ANTIGEN ANTIBODY REACTION; ARTICLE; BIOLUMINESCENCE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; ENZYME STABILITY; FEMALE; GENE EXPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RENILLA; TUMOR DIAGNOSIS; TUMOR XENOGRAFT;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BISPECIFIC; CARCINOEMBRYONIC ANTIGEN; CELL LINE, TUMOR; HUMANS; LUCIFERASES; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; NEOPLASMS; PROTEIN ENGINEERING; RATS; RECOMBINANT FUSION PROTEINS; RENILLA;

MUS MUSCULUS; RENILLA LUCIFERASE;

EID: 33748763812     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzl030     Document Type: Article

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