메뉴 건너뛰기




Volumn 19, Issue 1, 2008, Pages 362-369

Novel single-chain Fv′ formats for the generation of immunoliposomes by site-directed coupling

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; IMMUNOLIPOSOME; SEPRASE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

EID: 38949108975     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc700349k     Document Type: Article
Times cited : (35)

References (37)
  • 1
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • Allen, T. M., and Cullis, P. R. (2004) Drug delivery systems: entering the mainstream. Science 303, 1818-1822.
    • (2004) Science , vol.303 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 2
    • 0032851735 scopus 로고    scopus 로고
    • Immunoliposomes for the targeted delivery of antitumor drugs
    • Mastrobattista, E., Koning, G. A., and Storm, G. (1999) Immunoliposomes for the targeted delivery of antitumor drugs. Adv. Drug Delivery Rev. 40, 103-127.
    • (1999) Adv. Drug Delivery Rev , vol.40 , pp. 103-127
    • Mastrobattista, E.1    Koning, G.A.2    Storm, G.3
  • 3
    • 0028929819 scopus 로고
    • Immunogenicity of immunoliposomes: Reactivity against species-specific IgG and liposomal phospholipids
    • Philipps, N. C., and Dahman, J. (1995) Immunogenicity of immunoliposomes: reactivity against species-specific IgG and liposomal phospholipids. Immunol. Lett. 45, 149-152.
    • (1995) Immunol. Lett , vol.45 , pp. 149-152
    • Philipps, N.C.1    Dahman, J.2
  • 4
    • 0037427945 scopus 로고    scopus 로고
    • The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stablized immunoliposomes
    • Bendas, G., Rothe, U., Scherphof, G. L., and Kamps, J. A. A. M. (2003) The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stablized immunoliposomes. Biochim. Biophys. Acta 1609, 63-70.
    • (2003) Biochim. Biophys. Acta , vol.1609 , pp. 63-70
    • Bendas, G.1    Rothe, U.2    Scherphof, G.L.3    Kamps, J.A.A.M.4
  • 5
    • 0042626531 scopus 로고    scopus 로고
    • Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison
    • Koning, G. A., Morselt, H. W. M., Gorter, A., Allen, T. M., Zalipsky, S., Scherphof, G. L., and Kamps, J. A. A. M. (2003) Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison. Pharm. Res. 20, 1249-1257.
    • (2003) Pharm. Res , vol.20 , pp. 1249-1257
    • Koning, G.A.1    Morselt, H.W.M.2    Gorter, A.3    Allen, T.M.4    Zalipsky, S.5    Scherphof, G.L.6    Kamps, J.A.A.M.7
  • 6
    • 32544452539 scopus 로고    scopus 로고
    • Immunoliposomes for cancer therapy
    • Kontermann, R. E. (2006) Immunoliposomes for cancer therapy. Curr. Opin. Mol. Ther. 8, 39-45.
    • (2006) Curr. Opin. Mol. Ther , vol.8 , pp. 39-45
    • Kontermann, R.E.1
  • 7
    • 1042290308 scopus 로고    scopus 로고
    • Improved therapeutic responses in a xenograft model of human B lmyphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab′ fragments
    • Sapra, P., Moase, E. H., Ma, J., and Allen, T. M. (2004) Improved therapeutic responses in a xenograft model of human B lmyphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab′ fragments. Clin. Cancer Res. 10, 1100-1111.
    • (2004) Clin. Cancer Res , vol.10 , pp. 1100-1111
    • Sapra, P.1    Moase, E.H.2    Ma, J.3    Allen, T.M.4
  • 8
    • 30344484440 scopus 로고    scopus 로고
    • Antibody engineering for the development of therapeutic antibodies
    • Kim, S. J., Park, Y., and Hong, H. J. (2005) Antibody engineering for the development of therapeutic antibodies. Mol. Cells 20, 17-29.
    • (2005) Mol. Cells , vol.20 , pp. 17-29
    • Kim, S.J.1    Park, Y.2    Hong, H.J.3
  • 9
    • 0034952304 scopus 로고    scopus 로고
    • Production of functionalized single-chain Fv antibody fragments to the ED-B domain of the B-isoform of fibronectin in Pichia pastoris
    • Marty, C., Scheidegger, P., Ballmer-Hofer, K., Klemenz, R., and Schwendener, R. A. (2001) Production of functionalized single-chain Fv antibody fragments to the ED-B domain of the B-isoform of fibronectin in Pichia pastoris. Protein Expression Purif. 21, 156-164.
    • (2001) Protein Expression Purif , vol.21 , pp. 156-164
    • Marty, C.1    Scheidegger, P.2    Ballmer-Hofer, K.3    Klemenz, R.4    Schwendener, R.A.5
  • 10
    • 18744427000 scopus 로고    scopus 로고
    • Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed agaisnt human endoglin (CD105)
    • Völkel, T., Hölig, P., Merdan, T., Müller, R., and Kontermann, R. E. (2004) Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed agaisnt human endoglin (CD105). Biochim. Biophys. Acta 1663, 158-166.
    • (2004) Biochim. Biophys. Acta , vol.1663 , pp. 158-166
    • Völkel, T.1    Hölig, P.2    Merdan, T.3    Müller, R.4    Kontermann, R.E.5
  • 12
    • 12344336363 scopus 로고    scopus 로고
    • Characterization of site-specific scFv PEGylation for tumor-targeting pharmaceuticals
    • Nataranja, A., Xiong, C.-Y., Albrecht, H., DeNardo, G. L., and DeNardo, S. J. (2005) Characterization of site-specific scFv PEGylation for tumor-targeting pharmaceuticals. Bioconjugate Chem. 16, 113-121.
    • (2005) Bioconjugate Chem , vol.16 , pp. 113-121
    • Nataranja, A.1    Xiong, C.-Y.2    Albrecht, H.3    DeNardo, G.L.4    DeNardo, S.J.5
  • 13
    • 33748804911 scopus 로고    scopus 로고
    • Krimner, E. M., Hepp, J., Hoffmann, P., Bruckmaier, S., Petersen, L., Petsch, S., Parr, L., Schuster, I., Mangold, S., Lorenczewski, G., Lutterbüse, P., Buziol, S., Hochheim, I., Volkland, J., Molhoj, M., Sriskandarajah, M., Strasser, M., Itin, C., Wolf, A., Basu, A., Yang, K., Filupa, D., Sorensen, P., Kufer, P., Baeuerle, P., and Raum, T. (2006) A highly stable polyenthylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration. Protein Eng., Des. Sel. 19, 461-470.
    • Krimner, E. M., Hepp, J., Hoffmann, P., Bruckmaier, S., Petersen, L., Petsch, S., Parr, L., Schuster, I., Mangold, S., Lorenczewski, G., Lutterbüse, P., Buziol, S., Hochheim, I., Volkland, J., Molhoj, M., Sriskandarajah, M., Strasser, M., Itin, C., Wolf, A., Basu, A., Yang, K., Filupa, D., Sorensen, P., Kufer, P., Baeuerle, P., and Raum, T. (2006) A highly stable polyenthylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration. Protein Eng., Des. Sel. 19, 461-470.
  • 14
    • 13244269945 scopus 로고    scopus 로고
    • Single-chain fragment variable antibody piezoimmunosensors
    • Shen, Z., Stryker, G. A., Mernaugh, R. L., Yu, L., Yan, H., and Zeng, X. (2005) Single-chain fragment variable antibody piezoimmunosensors. Anal. Chem. 77, 797-805.
    • (2005) Anal. Chem , vol.77 , pp. 797-805
    • Shen, Z.1    Stryker, G.A.2    Mernaugh, R.L.3    Yu, L.4    Yan, H.5    Zeng, X.6
  • 16
    • 33644660779 scopus 로고    scopus 로고
    • Rigid, specific, and discrete gold nanoparticle/antibody conjugates
    • Ackerson, C. J., Jadzinsky, P. D., Jensen, G. J., and Romberg, R. D. (2006) Rigid, specific, and discrete gold nanoparticle/antibody conjugates. J. Am. Chem. Soc. 128, 2635-2640.
    • (2006) J. Am. Chem. Soc , vol.128 , pp. 2635-2640
    • Ackerson, C.J.1    Jadzinsky, P.D.2    Jensen, G.J.3    Romberg, R.D.4
  • 17
    • 0029077481 scopus 로고    scopus 로고
    • 2 made by protein folding and bonded through C-terminal cysteinyl peptides. Protein Eng. 8, 301-314.
    • 2 made by protein folding and bonded through C-terminal cysteinyl peptides. Protein Eng. 8, 301-314.
  • 19
    • 0842263617 scopus 로고    scopus 로고
    • Production of soluble scFvs with C-terminal-free thiol for site-specific conjugation or stable dimeric scFvs on demand
    • Albrecht, H., Burke, P. A., Natarajan, A., Xiong, C. Y., Kalicinsky, M., DeNardo, G. L., and DeNardo, S. J. (2004) Production of soluble scFvs with C-terminal-free thiol for site-specific conjugation or stable dimeric scFvs on demand. Bioconjugate Chem. 15, 16-26.
    • (2004) Bioconjugate Chem , vol.15 , pp. 16-26
    • Albrecht, H.1    Burke, P.A.2    Natarajan, A.3    Xiong, C.Y.4    Kalicinsky, M.5    DeNardo, G.L.6    DeNardo, S.J.7
  • 21
    • 33644857036 scopus 로고    scopus 로고
    • Monospecific bivalent scFv-SH: Effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility
    • Albrecht, H., DeNardo, G. L., and DeNardo, S. J. (2006) Monospecific bivalent scFv-SH: effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility. J. Immunol. Methods 310, 100-116.
    • (2006) J. Immunol. Methods , vol.310 , pp. 100-116
    • Albrecht, H.1    DeNardo, G.L.2    DeNardo, S.J.3
  • 22
    • 34447499944 scopus 로고    scopus 로고
    • Single-chain Fv immunoliposomes for the targeting of fibroblast activation protein-expressing tumor stromal cells
    • Baum, P., Müller, D., Rüger, R., and Kontermann, R. E. (2007) Single-chain Fv immunoliposomes for the targeting of fibroblast activation protein-expressing tumor stromal cells. J. Drug Target. 15, 399-406.
    • (2007) J. Drug Target , vol.15 , pp. 399-406
    • Baum, P.1    Müller, D.2    Rüger, R.3    Kontermann, R.E.4
  • 23
    • 30644469546 scopus 로고    scopus 로고
    • Generation of immunoliposomes using recombinant single-chain Fv fragment bound to Ni-NTA-liposomes
    • Rüger, R., Müller, D., Fahr, A., and Kontermann, R. E. (2005) Generation of immunoliposomes using recombinant single-chain Fv fragment bound to Ni-NTA-liposomes. J. Drug Target. 13, 399-406.
    • (2005) J. Drug Target , vol.13 , pp. 399-406
    • Rüger, R.1    Müller, D.2    Fahr, A.3    Kontermann, R.E.4
  • 24
    • 13544268486 scopus 로고    scopus 로고
    • Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE liposome-inserting conjugate. 1. Gram-scale production and purification
    • Nellis (2005) Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE liposome-inserting conjugate. 1. Gram-scale production and purification. Biotechnol. Prog. 21, 205-220.
    • (2005) Biotechnol. Prog , vol.21 , pp. 205-220
    • Nellis1
  • 25
    • 0034458999 scopus 로고    scopus 로고
    • WAM - an improved algorithm for modelling antibodies on the Web
    • Whitelegg, N. R. J., and Rees, A. R. (2000) WAM - an improved algorithm for modelling antibodies on the Web. Protein Eng. 13, 819-824.
    • (2000) Protein Eng , vol.13 , pp. 819-824
    • Whitelegg, N.R.J.1    Rees, A.R.2
  • 26
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • Sali, A., and Blundell, T. L. (1993) Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234, 779-815.
    • (1993) J. Mol. Biol , vol.234 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 27
    • 0027490731 scopus 로고
    • Recognition of errors in three-dimensional structures of proteins
    • Sippl, M. J. (1993) Recognition of errors in three-dimensional structures of proteins. Proteins 17, 355-362.
    • (1993) Proteins , vol.17 , pp. 355-362
    • Sippl, M.J.1
  • 28
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Crystallogr. 26, 283-291.
    • (1993) J. Appl. Crystallogr , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 30
    • 0032858556 scopus 로고    scopus 로고
    • A combinatorial approach to producing sterically stabilized (stealth) immunoliposomal drugs
    • Ishida, T., Iden, D. L., and Allen, T. M. (1999) A combinatorial approach to producing sterically stabilized (stealth) immunoliposomal drugs. FEBS Lett. 460, 129-133.
    • (1999) FEBS Lett , vol.460 , pp. 129-133
    • Ishida, T.1    Iden, D.L.2    Allen, T.M.3
  • 31
    • 0036420573 scopus 로고    scopus 로고
    • Use of the post-insertion method for the formation of ligand-coupled liposomes
    • Allen, T. M., Sapra, P., and Moase, E. (2002) Use of the post-insertion method for the formation of ligand-coupled liposomes. Cell. Mol. Biol. Lett. 7, 889-894.
    • (2002) Cell. Mol. Biol. Lett , vol.7 , pp. 889-894
    • Allen, T.M.1    Sapra, P.2    Moase, E.3
  • 32
    • 0034726412 scopus 로고    scopus 로고
    • Effects of unpaired cyteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli
    • Schmiedl., A., Breitling, F., Winter, C. H., Queitsch, I., and Dübel, S. (2000) Effects of unpaired cyteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli. J. Immunol. Methods 242, 101-114.
    • (2000) J. Immunol. Methods , vol.242 , pp. 101-114
    • Schmiedl, A.1    Breitling, F.2    Winter, C.H.3    Queitsch, I.4    Dübel, S.5
  • 33
    • 0037731636 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells
    • Mamot, C., Drummond, D. C., Greiser, U., Hong, K., Kirpotin, D. B., Marks, J. D., and Park, J. W. (2003) Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res. 63, 3154-3161.
    • (2003) Cancer Res , vol.63 , pp. 3154-3161
    • Mamot, C.1    Drummond, D.C.2    Greiser, U.3    Hong, K.4    Kirpotin, D.B.5    Marks, J.D.6    Park, J.W.7
  • 34
    • 33845519894 scopus 로고    scopus 로고
    • Expression and purification of two anti-CD19 single chain Fv fragments for targeting of liposomes to CD19-expressing cells
    • Cheng, W. W. K., Das, D., Suresh, M., and Allen, T. M. (2007) Expression and purification of two anti-CD19 single chain Fv fragments for targeting of liposomes to CD19-expressing cells. Biochim. Biophys. Acta 1768, 21-29.
    • (2007) Biochim. Biophys. Acta , vol.1768 , pp. 21-29
    • Cheng, W.W.K.1    Das, D.2    Suresh, M.3    Allen, T.M.4
  • 35
    • 29444439367 scopus 로고    scopus 로고
    • Targeting of immunoliposomes to endothelial cells expressing VCAM: A future strategy in cancer therapy
    • Gosk, S., Gottstein, C., and Bendas, G. (2005) Targeting of immunoliposomes to endothelial cells expressing VCAM: a future strategy in cancer therapy. Int. J. Clin. Pharmacol. Ther. 43, 581-582.
    • (2005) Int. J. Clin. Pharmacol. Ther , vol.43 , pp. 581-582
    • Gosk, S.1    Gottstein, C.2    Bendas, G.3
  • 36
    • 33645215307 scopus 로고    scopus 로고
    • Target ability and therapy efficacy of immunoliposomes using a humanized antihepatoma disulfide- stabilized Fv fragment on tumor cells
    • Hu, H., Chen, D., Liu, Y., Deng, Y., Yang, S., Qiao, M., Zhao, J., and Zhao, X. (2006) Target ability and therapy efficacy of immunoliposomes using a humanized antihepatoma disulfide- stabilized Fv fragment on tumor cells. J. Pharm. Sci. 95, 192-199.
    • (2006) J. Pharm. Sci , vol.95 , pp. 192-199
    • Hu, H.1    Chen, D.2    Liu, Y.3    Deng, Y.4    Yang, S.5    Qiao, M.6    Zhao, J.7    Zhao, X.8
  • 37
    • 0037255597 scopus 로고    scopus 로고
    • Overview of tag protein fusions: From molecular and biochemical fundamentals to commercial systems
    • Terpe, K. (2003) Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems. Appl. Microbiol. Biotechnol. 60, 523-533.
    • (2003) Appl. Microbiol. Biotechnol , vol.60 , pp. 523-533
    • Terpe, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.