Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications

Journal of Immunological Methods

Volumn 253, Issue 1-2, 2001, Pages 195-208

  Yazaki, Paul J ^a   Shively, Louise ^a   Clark, Cheryl ^a   Cheung, Chia Wei ^a   Le, William ^a   Szpikowska, Barbara ^a   Shively, John E ^a   Raubitschek, Andrew A ^a   Wu, Anna M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Antibody fragments; CEA; Mammalian expression; Radioimmunoscintigraphy

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; HYDROXYAPATITE; RECOMBINANT ANTIBODY;

ANION EXCHANGE CHROMATOGRAPHY; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ARTICLE; CERAMICS; CONTROLLED STUDY; HOLLOW FIBER MEMBRANE; MAMMAL; MEMBRANE REACTOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TUMOR;

ANTIBODIES, MONOCLONAL; BIOREACTORS; CARCINOEMBRYONIC ANTIGEN; CHROMATOGRAPHY, ION EXCHANGE; CLINICAL TRIALS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; NEOPLASMS; RECOMBINANT PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0035400469     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00388-X     Document Type: Article

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