Characterization and drug release investigation of amorphous drug-hydroxypropyl methylcellulose composites made via supercritical carbon dioxide assisted impregnation

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 4, 2008, Pages 1112-1119

  Gong, Kenan ^a   Rehman, Ihtesham U ^b   Darr, Jawwad A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Amorphous; Hydroxypropylmethyl cellulose; Impregnation; Indomethacin; sc CO2; Supercritical fluid

Indexed keywords

CARBON DIOXIDE; CARBONYL DERIVATIVE; CARBOXYLIC ACID; HYDROXYL GROUP; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN; POLYMER;

ANALYTIC METHOD; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG RELEASE; HYDROGEN BOND; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBON DIOXIDE; COLD TEMPERATURE; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; INDOMETHACIN; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 58049220307     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.08.031     Document Type: Article

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