Multicomponent complex formation between vinpocetine, cyclodextrins, tartaric acid and water-soluble polymers monitored by NMR and solubility studies

European Journal of Pharmaceutical Sciences

Volumn 24, Issue 1, 2005, Pages 1-13

  Ribeiro, Laura ^a   Carvalho, Rui A ^b   Ferreira, Domingos C ^c   Veiga, Francisco J B ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

1H NMR; Cyclodextrins; Multicomponent complexes; Phase solubility studies; Vinpocetine; Water soluble polymers

Indexed keywords

BETA CYCLODEXTRIN; BETA CYCLODEXTRIN SULFOBUTYL ETHER; POLYMER; PROTON; TARTARIC ACID; VINPOCETINE; WATER;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; DRUG SOLUBILITY; GEOMETRY; HYDROPHOBICITY; MOLECULAR INTERACTION; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILIZATION;

CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYMERS; SOLUBILITY; TARTRATES; VINCA ALKALOIDS; WATER;

EID: 11144224538     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2004.09.003     Document Type: Article

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