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Volumn 6, Issue 6, 2008, Pages 350-356

Prognostic and therapeutic implications of Apc mutation in colorectal cancer

Author keywords

Adenomatous polyposis coli; Colorectal cancer

Indexed keywords


EID: 58049216512     PISSN: 1479666X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1479-666X(08)80007-8     Document Type: Review
Times cited : (8)

References (87)
  • 1
    • 0034734896 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Epidemiology
    • Boyle P, Langman JS. ABC of colorectal cancer: Epidemiology. BMJ 2000;321(7264):805-8
    • (2000) BMJ , vol.321 , Issue.7264 , pp. 805-808
    • Boyle, P.1    Langman, J.S.2
  • 2
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumourigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumourigenesis. Cell 1990;61(5):759-67
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 4
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • Fodde R. The APC gene in colorectal cancer. Eur J Cancer 2002;38(7):867-71
    • (2002) Eur J Cancer , vol.38 , Issue.7 , pp. 867-871
    • Fodde, R.1
  • 5
    • 0026562404 scopus 로고
    • Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
    • Su LK, Kinzler KW, Vogelstein B, et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256(5057):668-70
    • (1992) Science , vol.256 , Issue.5057 , pp. 668-670
    • Su, L.K.1    Kinzler, K.W.2    Vogelstein, B.3
  • 6
    • 0036066584 scopus 로고    scopus 로고
    • Gastrointestinal stem cells
    • Brittan M, Wright NA. Gastrointestinal stem cells. J Pathol 2002;197(4):492-509
    • (2002) J Pathol , vol.197 , Issue.4 , pp. 492-509
    • Brittan, M.1    Wright, N.A.2
  • 7
    • 0036007425 scopus 로고    scopus 로고
    • The intestinal epithelial stem cell
    • Marshman E, Booth C, Potten CS. The intestinal epithelial stem cell. Bioessays 2002;24(1):91-98
    • (2002) Bioessays , vol.24 , Issue.1 , pp. 91-98
    • Marshman, E.1    Booth, C.2    Potten, C.S.3
  • 8
    • 0036591968 scopus 로고    scopus 로고
    • Intestinal stem cells protect their genome by selective segregation of template DNA strands
    • Potten CS, Owen G, Booth D. Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci 2002;115 (Pt 11):2381-88
    • (2002) J Cell Sci , vol.115 , Issue.PART 11 , pp. 2381-2388
    • Potten, C.S.1    Owen, G.2    Booth, D.3
  • 9
    • 36549015816 scopus 로고    scopus 로고
    • Expansion of a mutated clone from stem cell to tumour
    • Leedham S, Wright N. Expansion of a mutated clone from stem cell to tumour. J Clin Pathol 2007
    • (2007) J Clin Pathol
    • Leedham, S.1    Wright, N.2
  • 10
    • 8444236025 scopus 로고    scopus 로고
    • The adenomatous polyposis coli protein: The Achilles heel of the gut epithelium
    • Nathke IS. The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium. Annu Rev Cell Dev Biol 2004;20:337-66
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 337-366
    • Nathke, I.S.1
  • 11
    • 33846419846 scopus 로고    scopus 로고
    • Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis
    • Dikovskaya D, Schiffmann D, Newton IP, et al. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J Cell Biol 2007;176(2):183-95
    • (2007) J Cell Biol , vol.176 , Issue.2 , pp. 183-195
    • Dikovskaya, D.1    Schiffmann, D.2    Newton, I.P.3
  • 12
    • 0036270763 scopus 로고    scopus 로고
    • The subcellular destinations of APC proteins
    • Bienz M. The subcellular destinations of APC proteins. Nat Rev Mol Cell Biol 2002;3(5):328-38
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.5 , pp. 328-338
    • Bienz, M.1
  • 13
    • 0036124896 scopus 로고    scopus 로고
    • TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling
    • Brantjes H, Barker N, van Es J, Clevers H. TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling. Biol Chem 2002;383(2):255-61
    • (2002) Biol Chem , vol.383 , Issue.2 , pp. 255-261
    • Brantjes, H.1    Barker, N.2    van Es, J.3    Clevers, H.4
  • 14
    • 0036860704 scopus 로고    scopus 로고
    • The Wnt signalling pathway
    • Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci 2002;115(Pt 21):3977-78
    • (2002) J Cell Sci , vol.115 , Issue.PART 21 , pp. 3977-3978
    • Huelsken, J.1    Behrens, J.2
  • 15
    • 0038636318 scopus 로고    scopus 로고
    • Tumor formation by genetic mutations in the components of the Wnt signaling pathway
    • Kikuchi A. Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Sci 2003;94(3):225-29
    • (2003) Cancer Sci , vol.94 , Issue.3 , pp. 225-229
    • Kikuchi, A.1
  • 16
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science 2002;296(5573):1644-46
    • (2002) Science , vol.296 , Issue.5573 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 17
    • 0036534586 scopus 로고    scopus 로고
    • TCF transcription factors, mediators of Wnt-signaling in development and cancer
    • van Noort M, Clevers H. TCF transcription factors, mediators of Wnt-signaling in development and cancer. Dev Biol 2002;244(1):1-8
    • (2002) Dev Biol , vol.244 , Issue.1 , pp. 1-8
    • van Noort, M.1    Clevers, H.2
  • 18
    • 33947177629 scopus 로고    scopus 로고
    • Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability
    • Kroboth K, Newton IP, Kita K, et al. Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability. Mol Biol Cell 2007;18(3):910-18
    • (2007) Mol Biol Cell , vol.18 , Issue.3 , pp. 910-918
    • Kroboth, K.1    Newton, I.P.2    Kita, K.3
  • 19
    • 2942668475 scopus 로고    scopus 로고
    • Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
    • Sansom OJ, Reed KR, Hayes AJ, et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev 2004;18(12):1385-90
    • (2004) Genes Dev , vol.18 , Issue.12 , pp. 1385-1390
    • Sansom, O.J.1    Reed, K.R.2    Hayes, A.J.3
  • 20
    • 0346849717 scopus 로고    scopus 로고
    • Chromosome instability in colorectal tumour cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
    • Green RA, Kaplan KB. Chromosome instability in colorectal tumour cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J Cell Biol 2003;163(5):949-61
    • (2003) J Cell Biol , vol.163 , Issue.5 , pp. 949-961
    • Green, R.A.1    Kaplan, K.B.2
  • 22
    • 0028000073 scopus 로고
    • Pheno-typic expression in familial adenomatous polyposis: Partial prediction by mutation analysis
    • Nugent KP, Phillips RK, Hodgson SV, et al. Pheno-typic expression in familial adenomatous polyposis: partial prediction by mutation analysis. Gut 1994;35(11):1622-23
    • (1994) Gut , vol.35 , Issue.11 , pp. 1622-1623
    • Nugent, K.P.1    Phillips, R.K.2    Hodgson, S.V.3
  • 23
    • 0032712853 scopus 로고    scopus 로고
    • Notable intrafamilial phenotypic variability in a kindred with familial adenomatous polyposis and an APC mutation in exon 9
    • Rozen P, Samuel Z, Shomrat R, Legum C. Notable intrafamilial phenotypic variability in a kindred with familial adenomatous polyposis and an APC mutation in exon 9. Gut 1999;45(6):829-33
    • (1999) Gut , vol.45 , Issue.6 , pp. 829-833
    • Rozen, P.1    Samuel, Z.2    Shomrat, R.3    Legum, C.4
  • 24
    • 0027724691 scopus 로고
    • Alleles of the APC gene: An attenuated form of familial polyposis
    • Spirio L, Olschwang S, Groden J, et al. Alleles of the APC gene: an attenuated form of familial polyposis. Cell 1993;75(5):951-57
    • (1993) Cell , vol.75 , Issue.5 , pp. 951-957
    • Spirio, L.1    Olschwang, S.2    Groden, J.3
  • 25
    • 0026651826 scopus 로고
    • Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients
    • Nagase H, Miyoshi Y, Horii A, et al. Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients. Cancer Res 1992;52(14):4055-57
    • (1992) Cancer Res , vol.52 , Issue.14 , pp. 4055-4057
    • Nagase, H.1    Miyoshi, Y.2    Horii, A.3
  • 26
    • 0030806577 scopus 로고    scopus 로고
    • An unusually severe phenotype for familial adenomatous polyposis
    • Eccles DM, Lunt PW, Wallis Y, et al. An unusually severe phenotype for familial adenomatous polyposis. Arch Dis Child 1997;77(5):431-35
    • (1997) Arch Dis Child , vol.77 , Issue.5 , pp. 431-435
    • Eccles, D.M.1    Lunt, P.W.2    Wallis, Y.3
  • 27
    • 0028213461 scopus 로고
    • Familial adenomatous polyposis: Mutation at codon 1309 and early onset of colon cancer
    • Caspari R, Friedl W, Mandl M, et al. Familial adenomatous polyposis: mutation at codon 1309 and early onset of colon cancer. Lancet 1994;343(8898):629-32
    • (1994) Lancet , vol.343 , Issue.8898 , pp. 629-632
    • Caspari, R.1    Friedl, W.2    Mandl, M.3
  • 28
    • 0028085264 scopus 로고
    • Regionally clustered APC mutations are associated with a severe phenotype and occur at a high frequency in new mutation cases of adenomatous polyposis coli
    • Gayther SA, Wells D, SenGupta SB, et al. Regionally clustered APC mutations are associated with a severe phenotype and occur at a high frequency in new mutation cases of adenomatous polyposis coli. Hum Mol Genet 1994;3(1):53-56
    • (1994) Hum Mol Genet , vol.3 , Issue.1 , pp. 53-56
    • Gayther, S.A.1    Wells, D.2    SenGupta, S.B.3
  • 29
    • 0028104602 scopus 로고
    • Mutational analysis of the first 14 exons of the adenomatous polyposis coli (APC) gene
    • Dobbie Z, Spycher M, Hurliman R, et al. Mutational analysis of the first 14 exons of the adenomatous polyposis coli (APC) gene. Eur J Cancer 1994;30A(11):1709-13
    • (1994) Eur J Cancer , vol.30 A , Issue.11 , pp. 1709-1713
    • Dobbie, Z.1    Spycher, M.2    Hurliman, R.3
  • 30
    • 0028117866 scopus 로고
    • Genotype-phenotype correlation between position of constitutional APC gene mutation and CHRPE expression in familial adenomatous polyposis
    • Wallis YL, Macdonald F, Hulten M, et al. Genotype-phenotype correlation between position of constitutional APC gene mutation and CHRPE expression in familial adenomatous polyposis. Hum Genet 1994;94(5):543-48
    • (1994) Hum Genet , vol.94 , Issue.5 , pp. 543-548
    • Wallis, Y.L.1    Macdonald, F.2    Hulten, M.3
  • 31
    • 0031781181 scopus 로고    scopus 로고
    • Genotype-phenotype correlations in attenuated adenomatous polyposis coli
    • Soravia C, Berk T, Madlensky L, et al. Genotype-phenotype correlations in attenuated adenomatous polyposis coli. Am J Hum Genet 1998;62(6):1290-301
    • (1998) Am J Hum Genet , vol.62 , Issue.6 , pp. 1290-1301
    • Soravia, C.1    Berk, T.2    Madlensky, L.3
  • 32
    • 0029897836 scopus 로고    scopus 로고
    • Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein
    • Friedl W, Meuschel S, Caspari R, et al. Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein. Hum Genet 1996;97(5):579-84
    • (1996) Hum Genet , vol.97 , Issue.5 , pp. 579-584
    • Friedl, W.1    Meuschel, S.2    Caspari, R.3
  • 33
    • 0028807360 scopus 로고
    • APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis
    • van der Luijt RB, Vasen HF, Tops CM, Breukel C, Fodde R, Meera Khan P. APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis. Hum Genet 1995;96(6):705-10
    • (1995) Hum Genet , vol.96 , Issue.6 , pp. 705-710
    • van der Luijt, R.B.1    Vasen, H.F.2    Tops, C.M.3    Breukel, C.4    Fodde, R.5    Meera Khan, P.6
  • 34
    • 0031980296 scopus 로고    scopus 로고
    • A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9
    • Young J, Simms LA, Tarish J, et al. A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9. Hum Mutat 1998;11(6):450-55
    • (1998) Hum Mutat , vol.11 , Issue.6 , pp. 450-455
    • Young, J.1    Simms, L.A.2    Tarish, J.3
  • 35
    • 33749185580 scopus 로고    scopus 로고
    • Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation
    • Sieber OM, Segditsas S, Knudsen AL, et al. Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation. Gut 2006;55(10):1440-48
    • (2006) Gut , vol.55 , Issue.10 , pp. 1440-1448
    • Sieber, O.M.1    Segditsas, S.2    Knudsen, A.L.3
  • 36
    • 6844252957 scopus 로고    scopus 로고
    • Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli
    • van der Luijt RB, Meera Khan P, Vasen HF, et al. Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli. Hum Genet 1996;98(6):727-34
    • (1996) Hum Genet , vol.98 , Issue.6 , pp. 727-734
    • van der Luijt, R.B.1    Meera Khan, P.2    Vasen, H.F.3
  • 37
    • 23944488225 scopus 로고    scopus 로고
    • The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma
    • Conlin A, Smith G, Carey FA, Wolf CR, Steele RJ. The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma. Gut 2005;54(9):1283-86
    • (2005) Gut , vol.54 , Issue.9 , pp. 1283-1286
    • Conlin, A.1    Smith, G.2    Carey, F.A.3    Wolf, C.R.4    Steele, R.J.5
  • 38
    • 20444445117 scopus 로고    scopus 로고
    • APC, K-ras, and p53 gene mutations in colorectal cancer patients: Correlation to clinicopathologic features and post-operative surveillance
    • Hsieh JS, Lin SR, Chang MY, et al. APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and post-operative surveillance. Am Surg 2005;71(4):336-43
    • (2005) Am Surg , vol.71 , Issue.4 , pp. 336-343
    • Hsieh, J.S.1    Lin, S.R.2    Chang, M.Y.3
  • 39
    • 0030568063 scopus 로고    scopus 로고
    • DNA alterations in sporadic colorectal tumors do not correlate with tumor staging diagnosed by the TNM system
    • Deuter R, Linz J, Pietsch S, Winde G, Hentsch S, Muller O. DNA alterations in sporadic colorectal tumors do not correlate with tumor staging diagnosed by the TNM system. Cancer Lett 1996;109 (1-2):161-69
    • (1996) Cancer Lett , vol.109 , Issue.1-2 , pp. 161-169
    • Deuter, R.1    Linz, J.2    Pietsch, S.3    Winde, G.4    Hentsch, S.5    Muller, O.6
  • 40
    • 18644370130 scopus 로고    scopus 로고
    • Mutations of the APC gene in human sporadic colorectal cancers
    • De Filippo C, Luceri C, Caderni G, et al. Mutations of the APC gene in human sporadic colorectal cancers. Scand J Gastroenterol 2002;37(9):1048-53
    • (2002) Scand J Gastroenterol , vol.37 , Issue.9 , pp. 1048-1053
    • De Filippo, C.1    Luceri, C.2    Caderni, G.3
  • 41
    • 3242796729 scopus 로고    scopus 로고
    • APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort Study
    • Luchtenborg M, Weijenberg MP, Roemen GM, et al. APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort Study. Carcinogenesis 2004;25(7):1219-26
    • (2004) Carcinogenesis , vol.25 , Issue.7 , pp. 1219-1226
    • Luchtenborg, M.1    Weijenberg, M.P.2    Roemen, G.M.3
  • 42
    • 11144344179 scopus 로고    scopus 로고
    • Wnt/beta-catenin-pathway as a molecular target for future anti-cancer therapeutics
    • Dihlmann S, von Knebel Doeberitz M. Wnt/beta-catenin-pathway as a molecular target for future anti-cancer therapeutics. Int J Cancer 2005;113(4):515-24
    • (2005) Int J Cancer , vol.113 , Issue.4 , pp. 515-524
    • Dihlmann, S.1    von Knebel Doeberitz, M.2
  • 43
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • Polakis P. The adenomatous polyposis coli (APC) tumor suppressor. Biochim Biophys Acta 1997;1332(3):F127-47
    • (1997) Biochim Biophys Acta , vol.1332 , Issue.3
    • Polakis, P.1
  • 44
    • 3042788940 scopus 로고    scopus 로고
    • COX-2 inhibition and colorectal cancer
    • Koehne CH, Dubois RN. COX-2 inhibition and colorectal cancer. Semin Oncol 2004;31(2 Suppl 7):12-21
    • (2004) Semin Oncol , vol.31 , Issue.2 SUPPL. 7 , pp. 12-21
    • Koehne, C.H.1    Dubois, R.N.2
  • 45
    • 28544444039 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
    • Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 2005;310(5753):1504-10
    • (2005) Science , vol.310 , Issue.5753 , pp. 1504-1510
    • Castellone, M.D.1    Teramoto, H.2    Williams, B.O.3    Druey, K.M.4    Gutkind, J.S.5
  • 46
    • 0032483712 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (part II)
    • Taketo MM. Cyclooxygenase-2 inhibitors in tumorigenesis (part II). J Natl Cancer Inst 1998;90(21):1609-20.
    • (1998) J Natl Cancer Inst , vol.90 , Issue.21 , pp. 1609-1620
    • Taketo, M.M.1
  • 47
    • 0032556188 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (part I)
    • Taketo MM. Cyclooxygenase-2 inhibitors in tumorigenesis (part I). J Natl Cancer Inst 1998;90(20):1529-36
    • (1998) J Natl Cancer Inst , vol.90 , Issue.20 , pp. 1529-1536
    • Taketo, M.M.1
  • 48
    • 0035951493 scopus 로고    scopus 로고
    • Cancer research. Anti-inflammatories inhibit cancer growth-but how?
    • Marx J. Cancer research. Anti-inflammatories inhibit cancer growth-but how? Science 2001;291(5504):581-82
    • (2001) Science , vol.291 , Issue.5504 , pp. 581-582
    • Marx, J.1
  • 49
    • 0031882916 scopus 로고    scopus 로고
    • Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
    • Chan TA, Morin PJ, Vogelstein B, Kinzler KW. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc Natl Acad Sci U S A 1998;95(2):681-6.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.2 , pp. 681-686
    • Chan, T.A.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 50
    • 0346881625 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition and mechanisms of colorectal cancer prevention
    • Chan TA. Cyclooxygenase inhibition and mechanisms of colorectal cancer prevention. Curr Cancer Drug Targets 2003;3(6):455-63
    • (2003) Curr Cancer Drug Targets , vol.3 , Issue.6 , pp. 455-463
    • Chan, T.A.1
  • 51
    • 0035348486 scopus 로고    scopus 로고
    • Aspirin-induced activation of the NF-kappaB signaling pathway: A novel mechanism for aspirin-mediated apoptosis in colon cancer cells
    • Stark LA, Din FV, Zwacka RM, Dunlop MG. Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. Faseb J 2001;15(7):1273-75
    • (2001) Faseb J , vol.15 , Issue.7 , pp. 1273-1275
    • Stark, L.A.1    Din, F.V.2    Zwacka, R.M.3    Dunlop, M.G.4
  • 52
    • 0036130051 scopus 로고    scopus 로고
    • NSAID inhibition of GI cancer growth: Clinical implications and molecular mechanisms of action
    • Husain SS, Szabo IL, Tamawski AS. NSAID inhibition of GI cancer growth: clinical implications and molecular mechanisms of action. Am J Gastroenterol 2002;97(3):542-53
    • (2002) Am J Gastroenterol , vol.97 , Issue.3 , pp. 542-553
    • Husain, S.S.1    Szabo, I.L.2    Tamawski, A.S.3
  • 53
    • 0036839817 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth
    • Wick M, Hurteau G, Dessev C, et al. Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth. Mol Pharmacol 2002;62(5):1207-14
    • (2002) Mol Pharmacol , vol.62 , Issue.5 , pp. 1207-1214
    • Wick, M.1    Hurteau, G.2    Dessev, C.3
  • 54
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun MJ, Namboodiri MM, Heath CW, Jr. Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 1991;325(23):1593-96
    • (1991) N Engl J Med , vol.325 , Issue.23 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 56
    • 0029150934 scopus 로고
    • Aspirin and the risk of colorectal cancer in women
    • Giovannucci E, Egan KM, Hunter DJ, et al. Aspirin and the risk of colorectal cancer in women. N Engl J Med 1995;333(10):609-14
    • (1995) N Engl J Med , vol.333 , Issue.10 , pp. 609-614
    • Giovannucci, E.1    Egan, K.M.2    Hunter, D.J.3
  • 57
    • 0035252741 scopus 로고    scopus 로고
    • The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/ TCF-4 signaling
    • Dihlmann S, Siermann A, von Knebel Doeberitz M. The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/ TCF-4 signaling. Oncogene 2001;20(5):645-53
    • (2001) Oncogene , vol.20 , Issue.5 , pp. 645-653
    • Dihlmann, S.1    Siermann, A.2    von Knebel Doeberitz, M.3
  • 58
    • 0034852575 scopus 로고    scopus 로고
    • Structural, dynamic, and enzymatic properties of mixed alpha/beta-oligonucleotides containing polarity reversals
    • Germann MW, Aramini JM, Kalisch BW, van de Sande JH. Structural, dynamic, and enzymatic properties of mixed alpha/beta-oligonucleotides containing polarity reversals. Nucleosides Nucleoticles Nucleic Acids 2001;20(4-7):493-39
    • (2001) Nucleosides Nucleoticles Nucleic Acids , vol.20 , Issue.4-7 , pp. 493-539
    • Germann, M.W.1    Aramini, J.M.2    Kalisch, B.W.3    van de Sande, J.H.4
  • 59
    • 0034057928 scopus 로고    scopus 로고
    • The effect of nonsteroidal anti-inflammatory drugs on human colorectal cancer cells: Evidence of different mechanisms of action
    • Smith ML, Hawcroft G, Hull MA. The effect of nonsteroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur J Cancer 2000;36(5):664-74
    • (2000) Eur J Cancer , vol.36 , Issue.5 , pp. 664-674
    • Smith, M.L.1    Hawcroft, G.2    Hull, M.A.3
  • 60
    • 0036199569 scopus 로고    scopus 로고
    • Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells
    • Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis 2002;23(1):107-14
    • (2002) Carcinogenesis , vol.23 , Issue.1 , pp. 107-114
    • Hawcroft, G.1    D'Amico, M.2    Albanese, C.3    Markham, A.F.4    Pestell, R.G.5    Hull, M.A.6
  • 62
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • Giardiello FM, Hamilton SR, Krush AJ, et al. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 1993;328(18):1313-16
    • (1993) N Engl J Med , vol.328 , Issue.18 , pp. 1313-1316
    • Giardiello, F.M.1    Hamilton, S.R.2    Krush, A.J.3
  • 63
    • 0025834849 scopus 로고
    • Sulindac causes regression of rectal polyps in familial adenomatous polyposis
    • Labayle D, Fischer D, Vielh P, et al. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology 1991;101(3):635-39
    • (1991) Gastroenterology , vol.101 , Issue.3 , pp. 635-639
    • Labayle, D.1    Fischer, D.2    Vielh, P.3
  • 65
    • 0028921222 scopus 로고
    • Effect of sulindac on sporadic colonic polyps
    • Ladenheim J, Garcia G, Titzer D, et al. Effect of sulindac on sporadic colonic polyps. Gastroenterology 1995;108(4):1083-7.
    • (1995) Gastroenterology , vol.108 , Issue.4 , pp. 1083-1087
    • Ladenheim, J.1    Garcia, G.2    Titzer, D.3
  • 66
    • 0035180690 scopus 로고    scopus 로고
    • Tcf4 can specifically recognize beta-catenin using alternative conformations
    • Graham TA, Ferkey DM, Mao F, Kimelman D, Xu W. Tcf4 can specifically recognize beta-catenin using alternative conformations. Nat Struct Biol 2001;8(12):1048-52
    • (2001) Nat Struct Biol , vol.8 , Issue.12 , pp. 1048-1052
    • Graham, T.A.1    Ferkey, D.M.2    Mao, F.3    Kimelman, D.4    Xu, W.5
  • 67
    • 0033635606 scopus 로고    scopus 로고
    • Crystal structure of a beta-catenin/Tcf complex
    • Graham TA, Weaver C, Mao F, Kimelman D, Xu W. Crystal structure of a beta-catenin/Tcf complex. Cell 2000;103(6):885-96
    • (2000) Cell , vol.103 , Issue.6 , pp. 885-896
    • Graham, T.A.1    Weaver, C.2    Mao, F.3    Kimelman, D.4    Xu, W.5
  • 69
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
    • Molenaar M, van de Wetering M, Oosterwegel M, et al. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996;86(3):391-99
    • (1996) Cell , vol.86 , Issue.3 , pp. 391-399
    • Molenaar, M.1    van de Wetering, M.2    Oosterwegel, M.3
  • 70
    • 0242331652 scopus 로고    scopus 로고
    • Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery
    • Su Y, Ishikawa S, Kojima M, Liu B. Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery. Proc Natl Acad Sci U S A 2003;100 (22):12729-34
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.22 , pp. 12729-12734
    • Su, Y.1    Ishikawa, S.2    Kojima, M.3    Liu, B.4
  • 71
    • 2542461324 scopus 로고    scopus 로고
    • A protein knockdown strategy to study the function of beta-catenin in tumorigenesis
    • Cong F, Zhang J, Pao W, Zhou P, Varmus H. A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. BMC Mol Biol 2003;4:10
    • (2003) BMC Mol Biol , vol.4 , pp. 10
    • Cong, F.1    Zhang, J.2    Pao, W.3    Zhou, P.4    Varmus, H.5
  • 72
    • 0346098155 scopus 로고    scopus 로고
    • Targeted degradation of beta-catenin by chimeric F-box fusion proteins
    • Liu J, Stevens J, Matsunami N, White RL. Targeted degradation of beta-catenin by chimeric F-box fusion proteins. Biochem Biophys Res Commun 2004;313(4):1023-29
    • (2004) Biochem Biophys Res Commun , vol.313 , Issue.4 , pp. 1023-1029
    • Liu, J.1    Stevens, J.2    Matsunami, N.3    White, R.L.4
  • 73
    • 0035076823 scopus 로고    scopus 로고
    • Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
    • Mulvihill S, Warren R, Venook A, et al. Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial. Gene Ther 2001;8(4):308-15
    • (2001) Gene Ther , vol.8 , Issue.4 , pp. 308-315
    • Mulvihill, S.1    Warren, R.2    Venook, A.3
  • 74
    • 0035863458 scopus 로고    scopus 로고
    • Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
    • Nemunaitis J, Khuri F, Ganly I, et al. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 2001;19(2):289-98
    • (2001) J Clin Oncol , vol.19 , Issue.2 , pp. 289-298
    • Nemunaitis, J.1    Khuri, F.2    Ganly, I.3
  • 75
    • 0033693231 scopus 로고    scopus 로고
    • Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
    • Nemunaitis J, Ganly I, Khuri F, et al. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 2000;60(22):6359-66
    • (2000) Cancer Res , vol.60 , Issue.22 , pp. 6359-6366
    • Nemunaitis, J.1    Ganly, I.2    Khuri, F.3
  • 76
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht JR, Bedford R, Abbruzzese JL, et al. A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin Cancer Res 2003;9(2):555-61
    • (2003) Clin Cancer Res , vol.9 , Issue.2 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3
  • 77
    • 0037087621 scopus 로고    scopus 로고
    • Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/ refractory epithelial ovarian cancer
    • Vasey PA, Shulman LN, Campos S, et al. Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/ refractory epithelial ovarian cancer. J Clin Oncol 2002;20(6):1562-69
    • (2002) J Clin Oncol , vol.20 , Issue.6 , pp. 1562-1569
    • Vasey, P.A.1    Shulman, L.N.2    Campos, S.3
  • 78
    • 0035120593 scopus 로고    scopus 로고
    • Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
    • Brunori M, Malerba M, Kashiwazaki H, Iggo R. Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway. J Virol 2001;75(6):2857-65
    • (2001) J Virol , vol.75 , Issue.6 , pp. 2857-2865
    • Brunori, M.1    Malerba, M.2    Kashiwazaki, H.3    Iggo, R.4
  • 79
    • 0033756217 scopus 로고    scopus 로고
    • Update on adenovirus and its vectors
    • Russell WC. Update on adenovirus and its vectors. J Gen Virol 2000;81(Pt 11):2573-604
    • (2000) J Gen Virol , vol.81 , Issue.PART 11 , pp. 2573-2604
    • Russell, W.C.1
  • 80
    • 0023820680 scopus 로고
    • Sensitization of transformed rat fibroblasts to killing by parvovirus minute virus of mice correlates with an increase in viral gene expression
    • Cornelis JJ, Spruyt N, Spegelaere P, et al. Sensitization of transformed rat fibroblasts to killing by parvovirus minute virus of mice correlates with an increase in viral gene expression. J Virol 1988;62(9):3438-44
    • (1988) J Virol , vol.62 , Issue.9 , pp. 3438-3444
    • Cornelis, J.J.1    Spruyt, N.2    Spegelaere, P.3
  • 81
    • 0023880478 scopus 로고
    • Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses H-1 virus and minute virus of mice
    • Cornelis JJ, Becquart P, Duponchel N, et al. Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses H-1 virus and minute virus of mice. J Virol 1988;62(5):1679-86
    • (1988) J Virol , vol.62 , Issue.5 , pp. 1679-1686
    • Cornelis, J.J.1    Becquart, P.2    Duponchel, N.3
  • 82
    • 0024393476 scopus 로고
    • Inhibition by parvovirus H-1 of the formation of tumors in nude mice and colonies in vitro by transformed human mammary epithelial cells
    • Dupressoir T, Vanacker JM, Cornelis JJ, Duponchel N, Rommelaere J. Inhibition by parvovirus H-1 of the formation of tumors in nude mice and colonies in vitro by transformed human mammary epithelial cells. Cancer Res 1989;49(12):3203-8.
    • (1989) Cancer Res , vol.49 , Issue.12 , pp. 3203-3208
    • Dupressoir, T.1    Vanacker, J.M.2    Cornelis, J.J.3    Duponchel, N.4    Rommelaere, J.5
  • 84
    • 0037388638 scopus 로고    scopus 로고
    • Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells
    • Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 2003;9(4):1291-300
    • (2003) Clin Cancer Res , vol.9 , Issue.4 , pp. 1291-1300
    • Verma, U.N.1    Surabhi, R.M.2    Schmaltieg, A.3    Becerra, C.4    Gaynor, R.B.5
  • 85
    • 34247187543 scopus 로고    scopus 로고
    • Myc deletion rescues Apc deficiency in the small intestine
    • Sansom OJ, Meniel VS, Muncan V, et al. Myc deletion rescues Apc deficiency in the small intestine. Nature 2007;446 (7136):676-79
    • (2007) Nature , vol.446 , Issue.7136 , pp. 676-679
    • Sansom, O.J.1    Meniel, V.S.2    Muncan, V.3
  • 86
    • 0242552468 scopus 로고    scopus 로고
    • Ongoing adjuvant trials with trastuzumab in breast cancer
    • Tan AR, Swain SM. Ongoing adjuvant trials with trastuzumab in breast cancer. Semin Oncol 2003;30 (5 Suppl 16):54-64
    • (2003) Semin Oncol , vol.30 , Issue.5 SUPPL. 16 , pp. 54-64
    • Tan, A.R.1    Swain, S.M.2
  • 87
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001;344(14):1031-37
    • (2001) N Engl J Med , vol.344 , Issue.14 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3


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