메뉴 건너뛰기




Volumn 4, Issue , 2003, Pages

A protein knockdown strategy to study the function of β-catenin in tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHIMERIC PROTEIN; CYCLIN D; MYC PROTEIN; UBIQUITIN PROTEIN LIGASE; UVOMORULIN; WNT PROTEIN;

EID: 2542461324     PISSN: 14712199     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2199-4-10     Document Type: Article
Times cited : (74)

References (32)
  • 1
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz A and Nusse R: Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998, 14:59-88.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 2
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse R and Varmus HE: Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 1982, 31:99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 3
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P: Wnt signaling and cancer. Genes Dev 2000, 14:1837-51.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 6
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O and McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398:422-6.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 8
    • 0028248461 scopus 로고
    • Cell-cell adhesion in invasion and metastasis of carcinomas
    • Behrens J and Birchmeier W: Cell-cell adhesion in invasion and metastasis of carcinomas. Cancer Treat Res 1994, 71:251-66.
    • (1994) Cancer Treat. Res. , vol.71 , pp. 251-266
    • Behrens, J.1    Birchmeier, W.2
  • 9
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dahl U, Semb H and Christofori G: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998, 392:190-3.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 10
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser M: Ubiquitin-dependent protein degradation. Annu Rev Genet 1996, 30:405-39.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 11
    • 0033279836 scopus 로고    scopus 로고
    • SCF and Cullin/Ring H2-based ubiquitin ligases
    • Deshaies RJ: SCF and Cullin/Ring H2-based ubiquitin ligases. Annu Rev Cell Dev Biol 1999, 15:435-67.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 435-467
    • Deshaies, R.J.1
  • 13
    • 0033068154 scopus 로고    scopus 로고
    • The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
    • JT Winston, Strack P, Beer-Romero P, Chu CY, Elledge SJ and Harper JW: The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev 1999, 13:270-83.
    • (1999) Genes Dev. , vol.13 , pp. 270-283
    • Winston, J.T.1    Strack, P.2    Beer-Romero, P.3    Chu, C.Y.4    Elledge, S.J.5    Harper, J.W.6
  • 14
    • 0033120593 scopus 로고    scopus 로고
    • Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha
    • Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z and Pan ZQ: Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. Mol Cell 1999, 3:527-33.
    • (1999) Mol. Cell , vol.3 , pp. 527-533
    • Tan, P.1    Fuchs, S.Y.2    Chen, A.3    Wu, K.4    Gomez, C.5    Ronai, Z.6    Pan, Z.Q.7
  • 15
    • 0033611567 scopus 로고    scopus 로고
    • The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin
    • Latres E, Chiaur DS and Pagano M: The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Oncogene 1999, 18:849-54.
    • (1999) Oncogene , vol.18 , pp. 849-854
    • Latres, E.1    Chiaur, D.S.2    Pagano, M.3
  • 16
    • 0033638333 scopus 로고    scopus 로고
    • Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins
    • Zhou P, Bogacki R, McReynolds L and Howley PM: Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Mol Cell 2000, 6:751-6.
    • (2000) Mol. Cell , vol.6 , pp. 751-756
    • Zhou, P.1    Bogacki, R.2    McReynolds, L.3    Howley, P.M.4
  • 21
    • 0035842902 scopus 로고    scopus 로고
    • Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
    • Hsu W, Shakya R and Costantini F: Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J Cell Biol 2001, 155:1055-64.
    • (2001) J. Cell Biol. , vol.155 , pp. 1055-1064
    • Hsu, W.1    Shakya, R.2    Costantini, F.3
  • 23
    • 0034653689 scopus 로고    scopus 로고
    • The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression
    • Shih IM, Yu J, He TC, Vogelstein B and Kinzler KW: The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Cancer Res 2000, 60:1671-6.
    • (2000) Cancer Res. , vol.60 , pp. 1671-1676
    • Shih, I.M.1    Yu, J.2    He, T.C.3    Vogelstein, B.4    Kinzler, K.W.5
  • 24
    • 0034720450 scopus 로고    scopus 로고
    • Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels
    • Neo SY, Zhang Y, Yaw LP, Li P and Lin SC: Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels. Biochem Biophys Res Commun 2000, 272:144-50.
    • (2000) Biochem. Biophys. Res. Commun. , vol.272 , pp. 144-150
    • Neo, S.Y.1    Zhang, Y.2    Yaw, L.P.3    Li, P.4    Lin, S.C.5
  • 27
    • 18744369031 scopus 로고    scopus 로고
    • Identification of a Wnt/ Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development
    • Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A and Wang J et al.: Identification of a Wnt/ Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell 2002, 111:673-85.
    • (2002) Cell , vol.111 , pp. 673-685
    • Kioussi, C.1    Briata, P.2    Baek, S.H.3    Rose, D.W.4    Hamblet, N.S.5    Herman, T.6    Ohgi, K.A.7    Lin, C.8    Gleiberman, A.9    Wang, J.10
  • 30
    • 0037704269 scopus 로고    scopus 로고
    • Proof-of-principle: Oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors
    • Kim JS, Crooks H, Foxworth A and Waldman T: Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors. Mol Cancer Ther 2002, 1:1355-9.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 1355-1359
    • Kim, J.S.1    Crooks, H.2    Foxworth, A.3    Waldman, T.4
  • 31
    • 0037025173 scopus 로고    scopus 로고
    • Cancer. Addiction to oncogenes - The Achilles heal of cancer
    • Weinstein IB: Cancer. Addiction to oncogenes - the Achilles heal of cancer. Science 2002, 297:63-4.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.