Eradication of pathogenic β-catenin by Skp1/Cullin/F box ubiquitination machinery

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 22, 2003, Pages 12729-12734

  Su, Yunyun ^a   Ishikawa, Shinji ^a   Kojima, Masayuki ^a   Liu, Bo ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CELL PROTEIN; CHIMERIC PROTEIN; CULLIN; F BOX PROTEIN; SKP1 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CANCER CELL CULTURE; CELL ADHESION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHEMICAL REACTION; COLORECTAL CANCER; CONJUGATION; CONTROLLED STUDY; CYTOPLASM; ERADICATION THERAPY; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; MALIGNANT TRANSFORMATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TECHNIQUE; TUMOR GROWTH; UBIQUITINATION;

BETA CATENIN; CELL DIVISION; CELL LINE; CLONING, MOLECULAR; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; LUCIFERASES; PLASMIDS; RECOMBINANT FUSION PROTEINS; SKP CULLIN F-BOX PROTEIN LIGASES; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; UBIQUITIN;

ANIMALIA;

EID: 0242331652     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2133261100     Document Type: Article

References (43)

1. Alberts, B., Bray, D, Lewis, J., Raff, M., Roberts, K. & Watson, J. D. (2002) Molecular Biology of the Cell (Garland, New York), 4th Ed.
2. Hunter, T. (1997) Cell 88, 333-346.
3. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-18298.
4. Thomas, P. J., Qu, B.-H. & Pedersen, P. L. (1995) Trends Biochem. Sci. 20, 456-459.
5. Aberle, H., Schwartz, H. & Kemler, R. (1996) J. Cell Biochem. 61, 514-523.
6. Bienz, M. & Clevers, H. (2000) Cell 103, 311-320.
7. Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B. & Polakis, P. (1995) Proc. Natl. Acad. Sci. USA 92, 3046-3050.
8. Polakis, P. (1997) Biochim. Biophys. Acta 1332, F127-F147.
9. Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C., Munemitsu, S. & Polakis, P. (1996) Science 272, 1023-1025.
10. Aberle, H., Bauer, A., Stappert, J., Kispert, A. & Kemler, R. (1997) EMBO J. 16, 3797-3804.
11. Behrens, J., Jerchow, B. A., Wurtele, M., Grimm, J., Asbrand, C., Wirtz, R., Kuhl, M., Wedlich, D. & Birchmeier, W. (1998) Science 280, 596-599.
12. Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S. & Kikuchi, A. (1998) EMBO J. 17, 1371-1384.
13. Behrens, J., von Kries, P. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R. & Birchmeier, W. (1996) Nature 382, 638-642.
14. Morin, P. J., Sparks, A. B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B. & Kinzler, K. W. (1997) Science, 275, 1787-1790.
15. Korinek, V., Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B. & Clevers, H. (1997) Science 275, 1784-1787.
16. Jug-Sik, K., Crooks, H., Dracheva, T., Nishanian, T. G., Singh, B., Jen, J. & Waldman, T. (2002) Cancer Res. 62, 2744-2748.
17. Chan, T. A., Wang, Z., Dang, L. H., Vogelstein, B. & Kinzler, K. W. (2002) Proc. Natl. Acad. Sci. USA 99, 8265-8270.
18. Kim, J. S., Crooks, H., Foxworth, A. & Waldman, T. (2002) Mol. Cancer Ther. 1, 1355-1359.
19. Gosink, M. K. & Vierstra, R. D. (1995) Proc. Natl. Acad. Sci. USA 92, 9117-9121.
20. Zhou, P., Bogachi, R., McReynolds, L. & Howley, P. M. (2000) Mol. Cell 6, 751-756.
21. Sakamoto, K. M., Kim, K. B., Kumagai, A., Mercurio, F., Crews, C. M. & Deshaies, R. J. (2001) Proc. Natl. Acad. Sci. USA 98, 8554-8559.
22. Waldman, T., Kinzler, K. W. & Vogelstein, B. (1995) Cancer Res. 55, 5187-5190.
23. Harlow, E. & Lane, D. (1999) Using Antibodies: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
24. Shih, I. M., Yu, J., He, T.-C., Vogelstein, B. & Kinsler, K. W. (2000) Cancer Res. 60, 1671-1676.
25. Rubinfeld, B., Souza, B., Albert, I., Muller, O., Chamberlain, S. H., Masiarz, F. R., Munemitsu, S. & Polakis, P. (1993) Science 262, 1731-1734.
26. Su, L. K., Vogelstein, B. & Kinzler, K. W. (1993) Science 262, 1734-1737.
27. Rubinfeld, B., Souza, B., Albert, I., Munemitsu, S. & Polakis, P. (1995) J. Biol. Chem. 270, 5549-5555.
28. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J. W. & Elledge, S. J. (1996) Cell 86, 263-274.
29. Marikawa, Y. and Elinson, R. P. (1998) Mech. Dev. 77, 75-80.
30. Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. & Nakayama, K. (1999) EMBO J. 18, 2401-2410.
31. Parsons, R., Li, G. M., Longley, M. J., Fang, W. H., Papadopoulos, N., Jen, J., de la Chapelle, A., Kinzler, K. W., Vogelstein, B. & Modrich, P. (1993) Cell 75, 1227-1236.
32. He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., Da Costa, L. T., Morin, P. J., Vogelstein, B. & Kinzler, K. W. (1998) Science 281, 1509-1512.
33. Elledge, S. J. & Harper, J. W. (1998) Biochim. Biophys. Acta 1377, M61-M70.
34. Hershko, A. & Ciechanover, A. (1992) Annu. Rev. Biochem. 61, 761-807.
35. Morin, P. J., Vogelstein, B. & Kinzler, K. W. (1996) Proc. Natl. Acad. Sci. USA 93, 7950-7954.
36. Van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A.-P., et al. (2002) Cell 111, 241-250.
37. Shirasawa, S., Furuse, M., Yokoyama, N. & Sasazuki, T. (1993) Science 260, 85-88.
38. Felsher, D. W. & Bishop, J. M. (1999) Proc. Natl. Acad. Sci. USA 96, 3940-3944.
39. Chin, L., Tam, A., Pomerantz, J., Wong, M., Holash, J., Bardeesy, N., Shen, Q., O'Hagan, R., Pantginis, J. & Zhou, H. (1999) Nature 400, 468-472.
40. Fields, S. & Song, O.-K. (1989) Nature 340, 245-246.
41. Boder, E. T. & Wittrup, K. D. (1997) Nat. Biotechnol. 15, 553-557.
42. Wu, G., Xu, G., Schulman, B. A., Jeffrey, P. D., Harper, J. W. & Pavletich, N. P. (2003) Mol. Cell 11, 1445-1456.
43. Orlicky, S., Tang, X., Willems, A., Tyers, M. & Sicheri, F. (2003) Cell 112, 243-356.