Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding

Biochemical and Biophysical Research Communications

Volumn 378, Issue 3, 2009, Pages 360-365

  Déliot, Nadine ^a,b,c   Chavent, Matthieu ^d   Nourry, Claire ^a,b,c   Lécine, Patrick ^a,b,c   Arnaud, Camille ^a,b,c   Hermant, Aurélie ^a,b,c   Maigret, Bernard ^d   Borg, Jean Paul ^a,b,c  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d Orpailleur Team Loria   (France)

Author keywords

Electrostatic interactions; Erbin PDZ; Non canonical PDZ binding; Proteins interaction; Smad3 MH2

Indexed keywords

ARGININE; ERBIN; GLUTAMIC ACID; PDZ PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODEL; COMPLEX FORMATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PDZ DOMAIN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SIMULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ARGININE; CELL LINE; GLUTAMIC ACID; HUMANS; PDZ DOMAINS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 57849133445     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.175     Document Type: Article

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