메뉴 건너뛰기




Volumn 48, Issue SUPPL. 1, 2009, Pages

Developing new antiviral agents for influenza treatment: What does the future hold?

Author keywords

[No Author keywords available]

Indexed keywords

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; ALPHA INTERFERON; AMANTADINE; ANTIVIRUS AGENT; CS 8958; DAS 181; FLUDASE; INTERFERON; OSELTAMIVIR; PERAMIVIR; R 118958; RIBAVIRIN; RIMANTADINE; SIALIDASE INHIBITOR; T 705; THYMOSIN ALPHA1; UNCLASSIFIED DRUG; ZANAMIVIR;

EID: 57749187455     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/591851     Document Type: Review
Times cited : (233)

References (77)
  • 1
    • 25844438380 scopus 로고    scopus 로고
    • Incidence of adamantane resistance among influenza A(H3N2) viruses isolated worldwide from 1994 to 2005: A cause for concern
    • Bright RA, Medina MJ, Xu X, et al. Incidence of adamantane resistance among influenza A(H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 2005; 366:1175-81.
    • (2005) Lancet , vol.366 , pp. 1175-1181
    • Bright, R.A.1    Medina, M.J.2    Xu, X.3
  • 2
    • 34447271704 scopus 로고    scopus 로고
    • Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide
    • Deyde VM, Xu X, Bright RA, et al. Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide. J Infect Dis 2007; 196:249-57.
    • (2007) J Infect Dis , vol.196 , pp. 249-257
    • Deyde, V.M.1    Xu, X.2    Bright, R.A.3
  • 4
    • 38949197905 scopus 로고    scopus 로고
    • Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada
    • McGeer A, Green KA, Plevneshi A, et al. Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis 2007; 45:1568-75.
    • (2007) Clin Infect Dis , vol.45 , pp. 1568-1575
    • McGeer, A.1    Green, K.A.2    Plevneshi, A.3
  • 5
    • 34447290889 scopus 로고    scopus 로고
    • Factors associated with early hospital discharge of adult influenza patients
    • Lee N, Chan PK, Choi KW, et al. Factors associated with early hospital discharge of adult influenza patients. Antivir Ther 2007; 12:501-8.
    • (2007) Antivir Ther , vol.12 , pp. 501-508
    • Lee, N.1    Chan, P.K.2    Choi, K.W.3
  • 6
    • 42549121263 scopus 로고    scopus 로고
    • Antiviral treatment for patients hospitalized with severe influenza may affect clinical outcomes
    • Lee N, Cockram C, Chan P, Hui D, Choi KW, Sung J. Antiviral treatment for patients hospitalized with severe influenza may affect clinical outcomes. Clin Infect Dis 2008; 46:1323-4.
    • (2008) Clin Infect Dis , vol.46 , pp. 1323-1324
    • Lee, N.1    Cockram, C.2    Chan, P.3    Hui, D.4    Choi, K.W.5    Sung, J.6
  • 7
    • 38349068756 scopus 로고    scopus 로고
    • Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus. Update on avian influenza A(H5N1) virus infection in humans. N Engl J Med 2008; 358:261-73
    • Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus. Update on avian influenza A(H5N1) virus infection in humans. N Engl J Med 2008; 358:261-73.
  • 8
    • 0035969781 scopus 로고    scopus 로고
    • Treatment of influenza with neuraminidase inhibitors: Virological implications
    • Roberts NA. Treatment of influenza with neuraminidase inhibitors: virological implications. Philos Trans R Soc Lond B Biol Sci 2001; 356:1895-7.
    • (2001) Philos Trans R Soc Lond B Biol Sci , vol.356 , pp. 1895-1897
    • Roberts, N.A.1
  • 10
    • 0024819536 scopus 로고
    • Emergence and apparent transmission of rimantadine-resistant influenza A virus in families
    • Hayden FG, Belshe RB, Clover RD, Hay AJ, Oakes MG, Soo W. Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. N Engl J Med 1989; 321:1696-702.
    • (1989) N Engl J Med , vol.321 , pp. 1696-1702
    • Hayden, F.G.1    Belshe, R.B.2    Clover, R.D.3    Hay, A.J.4    Oakes, M.G.5    Soo, W.6
  • 11
    • 0035121720 scopus 로고    scopus 로고
    • Whitley RJ, Hayden FG, Reisinger KS, et al. Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J 2001; 20:127-33 (erratum: Pediatr Infect Dis J 2001; 20:421).
    • Whitley RJ, Hayden FG, Reisinger KS, et al. Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J 2001; 20:127-33 (erratum: Pediatr Infect Dis J 2001; 20:421).
  • 12
    • 0023260541 scopus 로고
    • Children with influenza A infection: Treatment with rimantadine
    • Hall CB, Dolin R, Gala CL, et al. Children with influenza A infection: treatment with rimantadine. Pediatrics 1987; 80:275-82.
    • (1987) Pediatrics , vol.80 , pp. 275-282
    • Hall, C.B.1    Dolin, R.2    Gala, C.L.3
  • 13
    • 14744293108 scopus 로고    scopus 로고
    • Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic
    • Ward P, Small I, Smith J, Suter P, Dutkowski R. Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic. J Antimicrob Chemother 2005; 55(Suppl 1):i5-21.
    • (2005) J Antimicrob Chemother , vol.55 , Issue.SUPPL. 1
    • Ward, P.1    Small, I.2    Smith, J.3    Suter, P.4    Dutkowski, R.5
  • 14
    • 4444369826 scopus 로고    scopus 로고
    • Resistant influenza A viruses in children treated with oseltamivir: Descriptive study
    • Kiso M, Mitamura K, Sakai-Tagawa Y, et al. Resistant influenza A viruses in children treated with oseltamivir: descriptive study. Lancet 2004; 364:759-65.
    • (2004) Lancet , vol.364 , pp. 759-765
    • Kiso, M.1    Mitamura, K.2    Sakai-Tagawa, Y.3
  • 15
    • 0037560121 scopus 로고    scopus 로고
    • High frequency of resistant viruses harboring different mutations in amantadine-treated children with influenza
    • Shiraishi K, Mitamura K, Sakai-Tagawa Y, Goto H, Sugaya N, Kawaoka Y. High frequency of resistant viruses harboring different mutations in amantadine-treated children with influenza. J Infect Dis 2003; 188:57-61.
    • (2003) J Infect Dis , vol.188 , pp. 57-61
    • Shiraishi, K.1    Mitamura, K.2    Sakai-Tagawa, Y.3    Goto, H.4    Sugaya, N.5    Kawaoka, Y.6
  • 16
    • 33644879977 scopus 로고    scopus 로고
    • Recovery of drug-resistant influenza virus from immunocompromised patients: A case series
    • Ison MG, Gubareva LV, Atmar RL, Treanor J, Hayden FG. Recovery of drug-resistant influenza virus from immunocompromised patients: a case series. J Infect Dis 2006; 193:760-4.
    • (2006) J Infect Dis , vol.193 , pp. 760-764
    • Ison, M.G.1    Gubareva, L.V.2    Atmar, R.L.3    Treanor, J.4    Hayden, F.G.5
  • 17
    • 17344373547 scopus 로고    scopus 로고
    • Common emergence of amantadine- and rimantadine-resistant influenza A viruses in symptomatic immunocompromised adults
    • Englund JA, Champlin RE, Wyde PR, et al. Common emergence of amantadine- and rimantadine-resistant influenza A viruses in symptomatic immunocompromised adults. Clin Infect Dis 1998; 26:1418-24.
    • (1998) Clin Infect Dis , vol.26 , pp. 1418-1424
    • Englund, J.A.1    Champlin, R.E.2    Wyde, P.R.3
  • 18
    • 33746724834 scopus 로고    scopus 로고
    • Prevention and control of influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
    • Smith NM, Bresee JS, Shay DK, et al. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2006; 55(RR-10):1-42.
    • (2006) MMWR Recomm Rep , vol.55 , Issue.RR-10 , pp. 1-42
    • Smith, N.M.1    Bresee, J.S.2    Shay, D.K.3
  • 19
    • 57749180756 scopus 로고    scopus 로고
    • Cox NJ. FDA H5N1 update: classification of H5N1 viruses and development of vaccine reference strains. US Food and Drug Administration Vaccines and Related Biological Products Advisory Committee presentation (Gaithersburg, Maryland), 2007. Available at: http://www.fda.gov/ohrms/dockets/AC/07/ slides/2007-4282S2_9.ppt. Accessed 17 August 2007.
    • Cox NJ. FDA H5N1 update: classification of H5N1 viruses and development of vaccine reference strains. US Food and Drug Administration Vaccines and Related Biological Products Advisory Committee presentation (Gaithersburg, Maryland), 2007. Available at: http://www.fda.gov/ohrms/dockets/AC/07/ slides/2007-4282S2_9.ppt. Accessed 17 August 2007.
  • 20
    • 25444432780 scopus 로고    scopus 로고
    • Consultation on Human Influenza A/H5. Avian influenza A(H5N1) infection in humans
    • Writing Committee of the World Health Organization WHO
    • Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. Avian influenza A(H5N1) infection in humans. N Engl J Med 2005; 353:1374-85.
    • (2005) N Engl J Med , vol.353 , pp. 1374-1385
  • 21
    • 33750285513 scopus 로고    scopus 로고
    • Prevention and treatment of influenza in high-risk groups: Children, pregnant women, immunocompromised hosts, and nursing home residents
    • Whitley RJ, Monto AS. Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents. J Infect Dis 2006; 194(Suppl 2):S133-8.
    • (2006) J Infect Dis , vol.194 , Issue.SUPPL. 2
    • Whitley, R.J.1    Monto, A.S.2
  • 22
    • 84921706204 scopus 로고    scopus 로고
    • Neuraminidase Inhibitor Susceptibility Network. Use of influenza antivirals during 2003-2004 and monitoring of neuraminidase inhibitor resistance
    • Neuraminidase Inhibitor Susceptibility Network. Use of influenza antivirals during 2003-2004 and monitoring of neuraminidase inhibitor resistance. Wkly Epidemiol Rec 2005; 80:156.
    • (2005) Wkly Epidemiol Rec , vol.80 , pp. 156
  • 23
    • 34247591533 scopus 로고    scopus 로고
    • Monitoring of neuraminidase inhibitor resistance among clinical influenza virus isolates in Japan during the 2003-2006 influenza seasons. Wkly Epidemiol Rec 2007; 82:149-50
    • Monitoring of neuraminidase inhibitor resistance among clinical influenza virus isolates in Japan during the 2003-2006 influenza seasons. Wkly Epidemiol Rec 2007; 82:149-50.
  • 24
    • 34047226373 scopus 로고    scopus 로고
    • Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors
    • Hatakeyama S, Sugaya N, Ito M, et al. Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors. JAMA 2007; 297:1435-42.
    • (2007) JAMA , vol.297 , pp. 1435-1442
    • Hatakeyama, S.1    Sugaya, N.2    Ito, M.3
  • 26
    • 29144528757 scopus 로고    scopus 로고
    • Oseltamivir resistance during treatment of influenza A(H5N1) infection
    • de Jong MD, Tran TT, Truong HK, et al. Oseltamivir resistance during treatment of influenza A(H5N1) infection. N Engl J Med 2005; 353:2667-72.
    • (2005) N Engl J Med , vol.353 , pp. 2667-2672
    • de Jong, M.D.1    Tran, T.T.2    Truong, H.K.3
  • 27
    • 27644439501 scopus 로고    scopus 로고
    • Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors
    • Mishin VP, Hayden FG, Gubareva LV. Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors. Antimicrob Agents Chemother 2005; 49:4515-20.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 4515-4520
    • Mishin, V.P.1    Hayden, F.G.2    Gubareva, L.V.3
  • 28
    • 12244295453 scopus 로고    scopus 로고
    • Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: Report of the Neuraminidase Inhibitor Susceptibility Network
    • Wetherall NT, Trivedi T, Zeller J, et al. Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the Neuraminidase Inhibitor Susceptibility Network. J Clin Microbiol 2003; 41:742-50.
    • (2003) J Clin Microbiol , vol.41 , pp. 742-750
    • Wetherall, N.T.1    Trivedi, T.2    Zeller, J.3
  • 29
    • 1842663228 scopus 로고    scopus 로고
    • Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: Prospective observational study
    • Chik KW, Li CK, Chan PK, et al. Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: prospective observational study. Hong Kong Med J 2004; 10:103-6.
    • (2004) Hong Kong Med J , vol.10 , pp. 103-106
    • Chik, K.W.1    Li, C.K.2    Chan, P.K.3
  • 30
    • 34447107067 scopus 로고    scopus 로고
    • Safety and tolerability of oseltamivir prophylaxis in hematopoietic stem cell transplant recipients: A retrospective case-control study
    • Vu D, Peck AJ, Nichols WG, et al. Safety and tolerability of oseltamivir prophylaxis in hematopoietic stem cell transplant recipients: a retrospective case-control study. Clin Infect Dis 2007; 45:187-93.
    • (2007) Clin Infect Dis , vol.45 , pp. 187-193
    • Vu, D.1    Peck, A.J.2    Nichols, W.G.3
  • 31
    • 33748747557 scopus 로고    scopus 로고
    • Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: A retrospective study at a major cancer center
    • Chemaly RF, Ghosh S, Bodey GP, et al. Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: a retrospective study at a major cancer center. Medicine (Baltimore) 2006; 85:278-87.
    • (2006) Medicine (Baltimore) , vol.85 , pp. 278-287
    • Chemaly, R.F.1    Ghosh, S.2    Bodey, G.P.3
  • 32
    • 7644229250 scopus 로고    scopus 로고
    • Influenza infections after hematopoietic stem cell transplantation: Risk factors, mortality, and the effect of antiviral therapy
    • Nichols WG, Guthrie KA, Corey L, Boeckh M. Influenza infections after hematopoietic stem cell transplantation: risk factors, mortality, and the effect of antiviral therapy. Clin Infect Dis 2004; 39:1300-6.
    • (2004) Clin Infect Dis , vol.39 , pp. 1300-1306
    • Nichols, W.G.1    Guthrie, K.A.2    Corey, L.3    Boeckh, M.4
  • 33
    • 4043056504 scopus 로고    scopus 로고
    • Use of oseltamivir to control influenza complications after bone marrow transplantation
    • Machado CM, Boas LS, Mendes AV, et al. Use of oseltamivir to control influenza complications after bone marrow transplantation. Bone Marrow Transplant 2004; 34:111-4.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 111-114
    • Machado, C.M.1    Boas, L.S.2    Mendes, A.V.3
  • 34
    • 0035190544 scopus 로고    scopus 로고
    • Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants
    • Gubareva LV, Webster RG, Hayden FG. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother 2001; 45:3403-8.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 3403-3408
    • Gubareva, L.V.1    Webster, R.G.2    Hayden, F.G.3
  • 35
    • 20244368656 scopus 로고    scopus 로고
    • Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: A multicenter study from Japan of the 2002-2003 influenza season
    • Kawai N, Ikematsu H, Iwaki N, et al. Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season. Clin Infect Dis 2005; 40:1309-16.
    • (2005) Clin Infect Dis , vol.40 , pp. 1309-1316
    • Kawai, N.1    Ikematsu, H.2    Iwaki, N.3
  • 36
    • 33746634739 scopus 로고    scopus 로고
    • A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: A Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons
    • Kawai N, Ikematsu H, Iwaki N, et al. A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons. Clin Infect Dis 2006; 43:439-44.
    • (2006) Clin Infect Dis , vol.43 , pp. 439-444
    • Kawai, N.1    Ikematsu, H.2    Iwaki, N.3
  • 37
    • 33846138361 scopus 로고    scopus 로고
    • Lower clinical effectiveness of oseltamivir against influenza B contrasted with influenza A infection in children
    • Sugaya N, Mitamura K, Yamazaki M, et al. Lower clinical effectiveness of oseltamivir against influenza B contrasted with influenza A infection in children. Clin Infect Dis 2007; 44:197-202.
    • (2007) Clin Infect Dis , vol.44 , pp. 197-202
    • Sugaya, N.1    Mitamura, K.2    Yamazaki, M.3
  • 38
    • 34248139179 scopus 로고    scopus 로고
    • Update: WHO-confirmed human cases of avian influenza A(H5N1) infection, 25 November 2003-24 November 2006
    • Update: WHO-confirmed human cases of avian influenza A(H5N1) infection, 25 November 2003-24 November 2006. Wkly Epidemiol Rec 2007; 82:41-7.
    • (2007) Wkly Epidemiol Rec , vol.82 , pp. 41-47
  • 39
    • 33845567555 scopus 로고    scopus 로고
    • WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A(H5N1) virus
    • Schünemann HJ, Hill SR, Kakad M, et al. WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A(H5N1) virus. Lancet Infect Dis 2007; 7:21-31.
    • (2007) Lancet Infect Dis , vol.7 , pp. 21-31
    • Schünemann, H.J.1    Hill, S.R.2    Kakad, M.3
  • 42
    • 33751517736 scopus 로고    scopus 로고
    • Antiviral agents active against influenza A viruses
    • De Clercq E. Antiviral agents active against influenza A viruses. Nat Rev Drug Discov 2006; 5:1015-25.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 1015-1025
    • De Clercq, E.1
  • 43
    • 36949001617 scopus 로고    scopus 로고
    • Strategies of development of antiviral agents directed against influenza virus replication
    • Hsieh HP, Hsu JT. Strategies of development of antiviral agents directed against influenza virus replication. Curr Pharm Des 2007; 13:3531-42.
    • (2007) Curr Pharm Des , vol.13 , pp. 3531-3542
    • Hsieh, H.P.1    Hsu, J.T.2
  • 44
    • 40849130832 scopus 로고    scopus 로고
    • Current and future antiviral therapy of severe seasonal and avian influenza
    • Beigel J, Bray M. Current and future antiviral therapy of severe seasonal and avian influenza. Antivir Res 2008; 78:91-102.
    • (2008) Antivir Res , vol.78 , pp. 91-102
    • Beigel, J.1    Bray, M.2
  • 45
    • 34447294010 scopus 로고    scopus 로고
    • Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A(H1N1) virus
    • Medeiros R, Rameix-Welti MA, Lorin V, et al. Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A(H1N1) virus. Antivir Ther 2007; 12:571-6.
    • (2007) Antivir Ther , vol.12 , pp. 571-576
    • Medeiros, R.1    Rameix-Welti, M.A.2    Lorin, V.3
  • 46
    • 54849438704 scopus 로고    scopus 로고
    • Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza
    • Taylor WR, Thinh BN, Anh GT, et al. Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza. PLoS ONE 2008; 3:e3410.
    • (2008) PLoS ONE , vol.3
    • Taylor, W.R.1    Thinh, B.N.2    Anh, G.T.3
  • 47
    • 0032996541 scopus 로고    scopus 로고
    • Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers
    • Cass LM, Efthymiopoulous C, Bye A. Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers. Clin Pharmacokinet 1999; 36(Suppl 1):1-11.
    • (1999) Clin Pharmacokinet , vol.36 , Issue.SUPPL. 1 , pp. 1-11
    • Cass, L.M.1    Efthymiopoulous, C.2    Bye, A.3
  • 48
    • 0032779292 scopus 로고    scopus 로고
    • Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection
    • Calfee DP, Peng AW, Cass LM, Lobo M, Hayden FG. Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection. Antimicrob Agents Chemother 1999; 43:1616-20.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1616-1620
    • Calfee, D.P.1    Peng, A.W.2    Cass, L.M.3    Lobo, M.4    Hayden, F.G.5
  • 49
    • 53249122897 scopus 로고    scopus 로고
    • Evaluation of intravenous zanamivir against experimental influenza A(H5N1) virus infection in the cynomolgus macaques
    • Stittelaar KJ, Tisdale M, van Amerongen G, et al. Evaluation of intravenous zanamivir against experimental influenza A(H5N1) virus infection in the cynomolgus macaques. Antivir Res 2008; 80:225-8.
    • (2008) Antivir Res , vol.80 , pp. 225-228
    • Stittelaar, K.J.1    Tisdale, M.2    van Amerongen, G.3
  • 50
    • 40849139031 scopus 로고    scopus 로고
    • The Southeast Asia Influenza Clinical Research Network: Development and challenges for a new multilateral research endeavor
    • Higgs ES, Hayden FG, Chotpitayasunondh T, Whitworth J, Farrar J. The Southeast Asia Influenza Clinical Research Network: development and challenges for a new multilateral research endeavor. Antivir Res 2008; 78:64-8.
    • (2008) Antivir Res , vol.78 , pp. 64-68
    • Higgs, E.S.1    Hayden, F.G.2    Chotpitayasunondh, T.3    Whitworth, J.4    Farrar, J.5
  • 51
    • 41649105849 scopus 로고    scopus 로고
    • Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with highly virulent influenza virus A/Vietnam/1203/04(H5N1)
    • Yun NE, Linde NS, Zacks MA, et al. Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with highly virulent influenza virus A/Vietnam/1203/04(H5N1). Virology 2008; 374:198-209.
    • (2008) Virology , vol.374 , pp. 198-209
    • Yun, N.E.1    Linde, N.S.2    Zacks, M.A.3
  • 52
    • 29044434743 scopus 로고    scopus 로고
    • Anti-influenza virus activity of peramivir in mice with single intramuscular injection
    • Bantia S, Arnold CS, Parker CD, Upshaw R, Chand P. Anti-influenza virus activity of peramivir in mice with single intramuscular injection. Antiviral Res 2006; 69:39-45.
    • (2006) Antiviral Res , vol.69 , pp. 39-45
    • Bantia, S.1    Arnold, C.S.2    Parker, C.D.3    Upshaw, R.4    Chand, P.5
  • 53
    • 57749170670 scopus 로고    scopus 로고
    • Kilpatrick JM, Harman LA, Collis PJ, Aitee G, Mead E, Alexander WJ. Pharmacokinetics and safety of peramivir by intramuscular administration [abstract P916]. In: Program and abstracts of the Options for the Control of Influenza VI Conference (Toronto). London: International Society for Influenza and Other Respiratory Virus Diseases, 2007.
    • Kilpatrick JM, Harman LA, Collis PJ, Aitee G, Mead E, Alexander WJ. Pharmacokinetics and safety of peramivir by intramuscular administration [abstract P916]. In: Program and abstracts of the Options for the Control of Influenza VI Conference (Toronto). London: International Society for Influenza and Other Respiratory Virus Diseases, 2007.
  • 54
    • 57749174423 scopus 로고    scopus 로고
    • Kohno S, Kida H, Mizuguchi M, Shimada J. A double-blind, placebo-controlled study of intravenous peramivir in acute influenza patients [abstract 302(V)]. Program and abstracts of the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America 46th Annual Meeting (Washington, DC). Washington, DC: American Society for Microbiology, 2008:328.
    • Kohno S, Kida H, Mizuguchi M, Shimada J. A double-blind, placebo-controlled study of intravenous peramivir in acute influenza patients [abstract 302(V)]. Program and abstracts of the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America 46th Annual Meeting (Washington, DC). Washington, DC: American Society for Microbiology, 2008:328.
  • 55
    • 9644275467 scopus 로고    scopus 로고
    • Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at once-weekly dosing regimen
    • Macdonald SJF, Watson KG, Cameron R, et al. Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at once-weekly dosing regimen. Antimicrob Agents Chemother 2004; 48:4542-9.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4542-4549
    • Macdonald, S.J.F.1    Watson, K.G.2    Cameron, R.3
  • 56
    • 57749191616 scopus 로고    scopus 로고
    • Rennecke J, Hirota T, Puchler K. R-118958, a unique anti-influenza agent: safety, tolerability and pharmacokinetics (PK) in healthy male volunteers [abstract F-1834]. In: Program and abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago). Washington, DC: American Society for Microbiology, 2003. Available at: http://gateway.nlm.nih.gov/ MeetingAbstracts/102266075.html. Accessed August 2007.
    • Rennecke J, Hirota T, Puchler K. R-118958, a unique anti-influenza agent: safety, tolerability and pharmacokinetics (PK) in healthy male volunteers [abstract F-1834]. In: Program and abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago). Washington, DC: American Society for Microbiology, 2003. Available at: http://gateway.nlm.nih.gov/ MeetingAbstracts/102266075.html. Accessed August 2007.
  • 57
    • 57749202595 scopus 로고    scopus 로고
    • LANI phase II completed - phase III scheduled [press release]
    • 105, 31 July
    • 105. Biota Holdings. LANI phase II completed - phase III scheduled [press release]. Melbourne: Biota Holdings, 31 July 2008.
    • (2008) Melbourne: Biota Holdings
    • Holdings, B.1
  • 58
    • 0036211719 scopus 로고    scopus 로고
    • In vitro and in vivo activities of anti-influenza virus compound T-705
    • Furuta Y, Takahashi K, Fukuda Y, et al. In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother 2002; 46:977-81.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 977-981
    • Furuta, Y.1    Takahashi, K.2    Fukuda, Y.3
  • 60
    • 33847688459 scopus 로고    scopus 로고
    • Efficacy of orally administered T-705 on lethal avian influenza A(H5N1) virus infections in mice
    • Sidwell RW, Barnard DL, Day CW, et al. Efficacy of orally administered T-705 on lethal avian influenza A(H5N1) virus infections in mice. Antimicrob Agents Chemother 2007; 51:845-51.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 845-851
    • Sidwell, R.W.1    Barnard, D.L.2    Day, C.W.3
  • 61
    • 33645765519 scopus 로고    scopus 로고
    • Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection
    • Malakhov MP, Aschenbrenner LM, Smee DF, et al. Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection. Antimicrob Agents Chemother 2006; 50:1470-9.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1470-1479
    • Malakhov, M.P.1    Aschenbrenner, L.M.2    Smee, D.F.3
  • 62
    • 38449093101 scopus 로고    scopus 로고
    • DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection
    • Belser JA, Lu X, Szretter KJ, et al. DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection. J Infect Dis 2007; 196:1493-9.
    • (2007) J Infect Dis , vol.196 , pp. 1493-1499
    • Belser, J.A.1    Lu, X.2    Szretter, K.J.3
  • 63
    • 0042656406 scopus 로고    scopus 로고
    • Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza. NIAID Collaborative Antiviral Study Group
    • Ison MG, Gnann JW Jr, Nagy-Agren S, et al. Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza. NIAID Collaborative Antiviral Study Group. Antivir Ther 2003; 8:183-90.
    • (2003) Antivir Ther , vol.8 , pp. 183-190
    • Ison, M.G.1    Gnann Jr, J.W.2    Nagy-Agren, S.3
  • 64
  • 65
    • 0014400598 scopus 로고
    • Combined inhibition of influenza virus reproduction in cell culture using interferon and amantadine
    • Lavrov SV, Eremkina EI, Orlova TG, Galegov GA, Soloviev VD, Zhdanov VM. Combined inhibition of influenza virus reproduction in cell culture using interferon and amantadine. Nature 1968; 217:856-7.
    • (1968) Nature , vol.217 , pp. 856-857
    • Lavrov, S.V.1    Eremkina, E.I.2    Orlova, T.G.3    Galegov, G.A.4    Soloviev, V.D.5    Zhdanov, V.M.6
  • 66
    • 0030012884 scopus 로고    scopus 로고
    • Efficacy of combination therapy with amantadine, thymosin alpha 1 and alpha/beta interferon in mice infected with influenza A virus
    • D'Agostini C, Palamara AT, Favalli C, et al. Efficacy of combination therapy with amantadine, thymosin alpha 1 and alpha/beta interferon in mice infected with influenza A virus. Int J Immunopharmacol 1996; 18:95-102.
    • (1996) Int J Immunopharmacol , vol.18 , pp. 95-102
    • D'Agostini, C.1    Palamara, A.T.2    Favalli, C.3
  • 67
    • 0028826587 scopus 로고
    • In vitro and in vivo sensitivity of a non-mouse-adapted influenza A (Beijing) virus infection to amantadine and ribavirin
    • Sidwell RW, Bailey KW, Wong MH, Huffman JH. In vitro and in vivo sensitivity of a non-mouse-adapted influenza A (Beijing) virus infection to amantadine and ribavirin. Chemotherapy 1995; 41:455-61.
    • (1995) Chemotherapy , vol.41 , pp. 455-461
    • Sidwell, R.W.1    Bailey, K.W.2    Wong, M.H.3    Huffman, J.H.4
  • 68
    • 33845462128 scopus 로고    scopus 로고
    • Rimantadine and oseltamivir demonstrate synergistic combination effect in an experimental infection with type A(H3N2) influenza virus in mice
    • Galabov AS, Simeonova L, Gegova G. Rimantadine and oseltamivir demonstrate synergistic combination effect in an experimental infection with type A(H3N2) influenza virus in mice. Antivir Chem Chemother 2006; 17:251-8.
    • (2006) Antivir Chem Chemother , vol.17 , pp. 251-258
    • Galabov, A.S.1    Simeonova, L.2    Gegova, G.3
  • 69
    • 55849102109 scopus 로고    scopus 로고
    • Oseltamivir-ribavirin combination therapy for highly pathogenic H5N1 influenza virus infection in mice
    • Ilyushina NA, Hay A, Yilmaz N, et al. Oseltamivir-ribavirin combination therapy for highly pathogenic H5N1 influenza virus infection in mice. Antimicrob Agents Chemother 2008; 52:3889-97.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3889-3897
    • Ilyushina, N.A.1    Hay, A.2    Yilmaz, N.3
  • 70
    • 0021352019 scopus 로고
    • Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro
    • Hayden FG, Schlepushkin AN, Pushkarskaya NL. Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro. Antimicrob Agents Chemother 1984; 25:53-7.
    • (1984) Antimicrob Agents Chemother , vol.25 , pp. 53-57
    • Hayden, F.G.1    Schlepushkin, A.N.2    Pushkarskaya, N.L.3
  • 71
    • 34948813121 scopus 로고    scopus 로고
    • Treatment with convalescent plasma for influenza A(H5N1) infection
    • Zhou B, Zhong N, Guan Y. Treatment with convalescent plasma for influenza A(H5N1) infection. N Engl J Med 2007; 357:1450-1.
    • (2007) N Engl J Med , vol.357 , pp. 1450-1451
    • Zhou, B.1    Zhong, N.2    Guan, Y.3
  • 72
    • 34447258584 scopus 로고    scopus 로고
    • Ong AK, Hayden FG. John F. Enders Lecture 2006: antivirals for influenza. J Infect Dis 2007; 196:181-90.
    • Ong AK, Hayden FG. John F. Enders Lecture 2006: antivirals for influenza. J Infect Dis 2007; 196:181-90.
  • 73
    • 33747156960 scopus 로고    scopus 로고
    • Antivirals for influenza: Historical perspectives and lessons learned
    • Hayden FG. Antivirals for influenza: historical perspectives and lessons learned. Antivir Res 2006; 71:372-8.
    • (2006) Antivir Res , vol.71 , pp. 372-378
    • Hayden, F.G.1
  • 75
    • 0029677207 scopus 로고    scopus 로고
    • Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection
    • Hayden FG, Sable CA, Connor JD, Lane J. Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection. Antivir Ther 1996; 1:51-6.
    • (1996) Antivir Ther , vol.1 , pp. 51-56
    • Hayden, F.G.1    Sable, C.A.2    Connor, J.D.3    Lane, J.4
  • 76
    • 34249669303 scopus 로고    scopus 로고
    • Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza
    • Simmons CP, Bernasconi NL, Suguitan AL, et al. Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med 2007; 4:e178.
    • (2007) PLoS Med , vol.4
    • Simmons, C.P.1    Bernasconi, N.L.2    Suguitan, A.L.3
  • 77
    • 33845609269 scopus 로고    scopus 로고
    • Successful treatment of avian influenza with convalescent plasma
    • Kong LK, Zhou BP. Successful treatment of avian influenza with convalescent plasma. Hong Kong Med J 2006; 12:489.
    • (2006) Hong Kong Med J , vol.12 , pp. 489
    • Kong, L.K.1    Zhou, B.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.