Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection

Antiviral Therapy

Volumn 1, Issue 1, 1996, Pages 51-56

  Hayden, Frederick G ^a   Sable, Carol A ^a   Connor, James D ^b   Lane, James ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; RIBAVIRIN;

ADULT; ARTICLE; BLOOD; BRONCHUS; CASE REPORT; CLINICAL TRIAL; FEMALE; HUMAN; INFLUENZA; INTRAVENOUS DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; MALE; METABOLISM; MIDDLE AGED; ORTHOMYXOVIRUS; PARAINFLUENZA VIRUS 2; TRACHEA; VIRUS INFECTION;

ADULT; ANTIVIRAL AGENTS; BRONCHI; FEMALE; HUMANS; INFLUENZA, HUMAN; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; ORTHOMYXOVIRIDAE; PARAINFLUENZA VIRUS 2, HUMAN; PARAMYXOVIRIDAE INFECTIONS; RIBAVIRIN; TRACHEA;

EID: 0029677207     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Austin RK, Trefts PE, Elintz M, Connor JD & Kagnoff ME. Sensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirin. Antimicrobial Agents & Chemotherapy 1983; 24:696-710.
2. Bernstein DI, Reuman PD, Sherwood JR, Young EC & Schiff GM. Ribavirin small-particle-aerosol treatment of influenza B virus infection. Antimicrobial Agents & Chemotherapy 1988; 32:761-764.
3. Couch R. National Institute of Allergy and Infectious Disease: Antiviral agents in influenza - summary of influenza workshop VIII. Journal of Infections Diseases 1976; 134:516-527.
4. Enria DA, Briggiler AM, Levis S, Vallejos D, Maiztegui JI & Canonico PG. Preliminary report tolerance and antiviral effect of ribavirin in patients with Argentine hemorrhagic fever. Antiviral Research 1987; 7:353-359.
5. Forni AL, Schluger NW & Roberts RB. Severe measles pneumonitis in adults: evaluation of clinical characteristics and therapy with intravenous ribavirin. Clinical Infections Diseases 1994; 19:454-462.
6. Hayden FG. Combinations of antiviral agents for treatment of influenza virus infections. Journal of Antimicrobial Chemotherapy 1986; 18:(suppl B):S177-183.
7. Hayden FG. Amantadine and rimantadine resistance in influenza A virus. Current Opinion in Infections Diseases 1994; 7:674-677.
8. Hayden FG, Cote KM & Douglas RG. Plaque inhibition assay for drug susceptibility testing of influenza viruses. Antimicrobial Agents & Chemotherapy 1980; 17:865-870.
9. Hayden FG, Rollins BS & Hay AJ. Anti-influenza virus activity of the compound LY253963. Antiviral Research 1990; 14:25-38.
10. Huggins JW. Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug. Reviews of Infectious Diseases 1989; 2 (Suppl 4):S750-761.
11. Huggins JW, Hsiang CM, Cosgriff TM, Guang MY, Smith JI, Wu ZO, LeDuc JW, Zheng ZM, Meegan JM, Qang QN, Oland DD, Gui XE, Gibbs PH, Yuan GH & Zhang TM. Prospective, double-blind, concurrent, placebo-controlled clinical trial of intravenous ribavirin therapy of hemorrhagic fever with renal syndrome. Journal of Infectious Diseases 1991; 164:1119-1127.
12. Klimov I, Rocha E, Hayden FG, Shult PA, Roumillat LF & Cox NJ. Prolonged shedding of amantadine-resistant influenza A viruses by immunodeficient patients: detection by PCR-restriction analysis. Journal of Infectious Diseases 1995; 172:1352-1355.
13. Knight V & Gilbert BE. Ribavirin aerosol treatment of influenza. In Antiviral Chemotherapy. Edited by V Knight & B Gilbert. Infectious Disease Clinics of North America 1987; 1:441-457.
14. Laskin OL, Lonstreth JA, Hart CC, Scavuzzo D, Kalman CM, Connor JD & Roberts RB. Ribavirin disposition in high-risk patients for acquired immunodeficiency syndrome. Clinical Pharmacology & Therapeutics 1987; 41:546-555.
15. Madren LK, Shipman C Jr & Hayden FG. In vitro inhibitory effects of combinations of anti-influenza agents. Antiviral Chemistry & Chemotherapy 1995; 6:109-113.
16. McCormick JB, King IJ, Webb PA, Scribner CL, Craven RB, Johnson KM, Elliott LH & Belmont-Williams R. Lassa fever. Effective therapy with ribavirin. New England Journal of Medicine 1986; 314:20-26.
17. Ray CG, Icenogle TB, Minnich LL, Copeland JG & Grogan TM. The use of intravenous ribavirin to treat influenza virus-associated acute myocarditis. Journal of Infectious Diseases 1989; 159:829-836.
18. Rodriguez WJ, Hall CB, Welliver R, Simoes EAF, Ryan ME, Stutman H, Johnson G, Van Dyke R, Groothuis JR, Arrobio J & Schnabel K. Efficacy and safety of aerosolized ribavirin in young children hospitalized with influenza: a double-blind, multicenter, placebo-controlled trial. Journal of Pediatrics 1994; 125:129-135.
19. Rollins BS, Elkhatieb AHA & Hayden FG. Comparative anti-influenza virus activity of 2′-deoxy-2′-fluororibosides in vitro. Antiviral Research 1993; 21:357-368.
20. Smee DF & Matthews TR. Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells. Antimicrobial Agents & Chemotherapy 1986; 30:117-121.