Polymorphic markers associated with genes responsible for lipid and carbohydrate metabolism disorders and insulin resistance in cancer patients

Molecular Biology

Volumn 42, Issue 6, 2008, Pages 843-851

  Ulybina, Yu M ^a   Imyanitov, E N ^a   Vasilyev, D A ^a   Berstein, L M ^a  

^a N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

Author keywords

Breast cancer; Diabetes; Endometrial cancer; Genetic polymorphism; Glucose intolerance; Insulin receptor substrate 1; Insulin resistance; Leptin receptor; Mitochondrial DNA; Mitochondrial uncoupling protein 2

Indexed keywords

EID: 57749176842     PISSN: 00268933     EISSN: 16083245     Source Type: Journal    
DOI: 10.1134/S0026893308060034     Document Type: Article

References (40)

1. Dil'man V.M. 1987. Chetyre modeli meditsiny (Four Models of Medicine). Leningrad: Meditsina.
2. Dedov I.I., Shestakova M.N. 2003. Sakharnyi diabet (Diabetes Mellitus). Moscow: Universum Publ.
3. P. Iozzo H. Beck-Nielsen M. Laakso 1999 Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance J. Clin. Endocrinol. Metab. 84 863 868
4. L.M. Berstein 2005 Clinical usage of hypolipidemic and antidiabetic drugs in the prevention and treatment of cancer Cancer Lett. 224 203 212
5. P.J. Goodwin M. Ennis K.I. Pritchard 2002 Fasting insulin and outcome in early-stage breast cancer: Results of a prospective cohort study J. Clin. Oncol. 20 42 51
6. S.A. Silvera M. Jain G.R. Howe 2005 Dietary carbohydrates and breast cancer risk: A prospective study of the roles of overall glycemic index and glycemic load Int. J. Cancer. 114 653 658
7. R.H. Eckel S.M. Grundy P.Z. Zimmet 2005 The metabolic syndrome Lancet. 365 1415 1428
8. G.M. Reaven 2003 The insulin resistance syndrome Curr. Atheroscler. Rep. 5 364 371
9. D.A. Lawlor G.D. Smith S. Ebrahim 2004 Hyperinsulinaemia and increased risk of breast cancer: Findings from the British Women's Heart and Health Study Cancer Causes Control. 15 267 275
10. E.E. Calle M.J. Thun 2004 Obesity and cancer Oncogene. 23 6365 6378
11. Bershtein L.M. 2004. Onkoendokrinologiya: traditsii, sovremennost' i perspektivy (Oncoendocrinology: Traditions, Current State, and Prospects). St. Petersburg: Nauka.
12. B. Vogelstein K.W. Kinzler 2004 Cancer genes and the pathways they control Nature Med. 10 789 799
13. L.D. Wood D.W. Parsons S. Jones 2007 The genomic landscapes of human breast and colorectal cancers Science. 318 1108 1113
14. E.N. Imyanitov A.V. Togo K.P. Hanson 2004 Searching for cancer-associated gene polymorphisms: promises and obstacles Cancer Lett. 204 3 14
15. J.C. Kaplan C. Junien 2000 Genomics and medicine: an anticipation. From Boolean Mendelian genetics to multifactorial molecular medicine C.R. Acad. Sci. III. 323 1167 1174
16. M. Laakso 2004 Gene variants, insulin resistance, and dyslipidaemia Curr. Opin. Lipidol. 15 115 120
17. A. Loktionov 2003 Common gene polymorphisms and nutrition: Emerging links with pathogenesis of multifactorial chronic diseases (review) J. Nutr. Biochem. 14 426 451
18. C.-W. Liou T.-K. Lin H.H. Weng 2007 A common mitochondrial DNA variant and increased body mass index as associated factors for development of type 2 diabetes: Additive effects of genetic and environmental factors J. Clin. Endocr. Metabol. 92 1235 1239
19. A.I. Gaziev A.Ya. Podlutskii 2003 Low efficiency of mitochondrial DNA repair system Tsitologiya. 45 403 417
20. V.P. Skulachev 1999 Mitochondrial physiology and pathology; Concepts of programmed death of organelles, cells and organisms Mol. Aspects Med. 20 139 184
21. D.C. Wallace 2005 A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine Annu. Rev. Genet. 39 359 407
22. A. Jellema M.P. Zeegers E.J. Feskens 2003 Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes: A meta-analysis of 27 studies Diabetologia. 46 990 995
23. T. Salopuro L. Pulkkinen J. Lindstrom 2005 Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study Int. J. Obes.(Lond). 29 1245 1251
24. R. Müllenbach P.J. Lagoda C. Welter 1989 An efficient salt-chloroform extraction of DNA from blood and tissues Trends Genet. 5 391 397
25. M.Yu. Shamanina V.A. Vavilin V.A. Mordvinov 2007 Polymerase chain reaction with real-time detection and its possible clinical applications Vestn. Ross. Akad. Med. Nauk. 7 37 26
26. A. Zaggini I.N. Waadin C.H. Lindgran 2007 Replication of genome-wide association signals in UK samples reveals risk leci for type 2 diabetes Science. 316 1336 1341
27. K. Hoffmann M. Mattheisen S. Dahm 2007 A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2 Diabetologia. 50 1418 1422
28. L.C. Richardson L.A. Pollack 2005 Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer Nature Clin. Pract. Oncol. 2 48 53
29. L.M. Bershtein V.M. Merabishvili N.V. Semenova 2007 Population analysis of combined cancer and diabetes mellitus: Frequency and specific features Vopr. Onkol. 53 285 290
30. M.L. Slattery W. Samowitz K. Curtin 2004 Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer Cancer Epidemiol. Bio-markers Prev. 13 1206 1214
31. K. Snoussi A.D. Strosberg N. Bouaouina 2006 Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma BMC Cancer 6 38
32. O. Portolés J.V. Sorli F. Francés 2006 Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain Eur. J. Epidemiol. 21 605 612
33. E. Rai S. Sharma A. Koul 2007 Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population Hum. Genet. 122 535 540
34. R.K. Bai S.M. Leal D. Covarrubias 2007 Mitochondrial genetic background modifies breast cancer risk Cancer Res. 67 4687 4694
35. J. Fan R. McKean-Cowdin L. Bernstein 2006 An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors Breast Cancer Res. Treat. 99 323 331
36. J.A. Canter A.R. Kallianpur F.F. Parl R.C. Millikan 2005 Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women Cancer Res. 65 8028 8033
37. Y. Yu Y. Hao L.A. Feig 2006 The R-Ras GTPase mediates cross talk between estrogen and insulin signaling in breast cancer cells Mol. Cell. Biol. 26 6372 6380
38. M.C. Maeso Fortuny B. Brito Diaz A. Cabrera de León 2006 Leptin, estrogens and cancer Mini Rev. Med. Chem. 6 897 907
39. J.F. Louet C. LeMay F. Mauvais-Jarvis 2004 Antidiabetic actions of estrogen: Insight from human and genetic mouse models Curr. Atheroscler Rep. 6 180 185
40. J.D. Yager N.E. Davidson 2006 Estrogen carcinogenesis in breast cancer N. Engl. J. Med. 354 270 282