Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracene (DMBA) induced spleen cell immunotoxicity

Toxicological Sciences

Volumn 86, Issue 1, 2005, Pages 68-74

  Gao, Jun ^a   Lauer, Fredine T ^a   Dunaway, Sandy ^a   Burchiel, Scott W ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

7,12 dimethylbenz(a)anthracene (DMBA); CYP1B1; Immunotoxicity; Spleen cell

Indexed keywords

CELL SURFACE MARKER; CORN OIL; CYTOCHROME P450 1B1; DIMETHYLBENZ[A]ANTHRACENE; IMMUNOGLOBULIN M ANTIBODY; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE; FEEDING; FEMALE; FLOW CYTOMETRY; IMMUNE DEFICIENCY; IMMUNITY; IMMUNOASSAY; IMMUNOTOXICITY; IN VITRO STUDY; LYMPHOCYTE SUBPOPULATION; MITOGENESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PLAQUE FORMING CELL; PROTEIN FUNCTION; SPLEEN CELL; T LYMPHOCYTE; WILD TYPE; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NATURAL KILLER CELL; SPLEEN;

OVIS ARIES; ZEA MAYS;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; B-LYMPHOCYTES; CARCINOGENS; FEMALE; FLOW CYTOMETRY; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLEEN; T-LYMPHOCYTES;

EID: 26944437097     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfi176     Document Type: Article

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