-
1
-
-
0037795635
-
Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro
-
Stathopulos PB, et al. (2003) Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro. Proc Natl Acad Sci USA 100:7021-7026.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7021-7026
-
-
Stathopulos, P.B.1
-
2
-
-
0042736853
-
ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization
-
DiDonato M, et al. (2003) ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization. J Mol Biol 332:601-615.
-
(2003)
J Mol Biol
, vol.332
, pp. 601-615
-
-
DiDonato, M.1
-
3
-
-
45949083132
-
SOD1 and amyotrophic lateral sclerosis: Mutations and oligomerization
-
Banci L, et al. (2008) SOD1 and amyotrophic lateral sclerosis: Mutations and oligomerization. PLoS ONE 3:e1677.
-
(2008)
PLoS ONE
, vol.3
-
-
Banci, L.1
-
4
-
-
4143133235
-
A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins
-
Linding R, Schymkowitz J, Rousseau F, Diella F, Serrano L (2004) A comparative study of the relationship between protein structure and beta-aggregation in globular and intrinsically disordered proteins. J Mol Biol 342:345-353.
-
(2004)
J Mol Biol
, vol.342
, pp. 345-353
-
-
Linding, R.1
Schymkowitz, J.2
Rousseau, F.3
Diella, F.4
Serrano, L.5
-
5
-
-
57749100302
-
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
-
Chattopadhyay M, et al. (2008) Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. Proc Natl Acad Sci USA 105:18663-18668.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18663-18668
-
-
Chattopadhyay, M.1
-
6
-
-
53049109088
-
Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in familial form of amyotrophic lateral sclerosis
-
Furukawa Y, Kaneko K, Yamanaka K, O'Halloran TV, Nukina N (2008) Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in familial form of amyotrophic lateral sclerosis. J Biol Chem 283:24167-24176.
-
(2008)
J Biol Chem
, vol.283
, pp. 24167-24176
-
-
Furukawa, Y.1
Kaneko, K.2
Yamanaka, K.3
O'Halloran, T.V.4
Nukina, N.5
-
7
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti F, Dobson CM (2006) Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 75:333-366.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
8
-
-
22244489417
-
Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants
-
Lindberg MJ, Bystrom R, Boknas N, Andersen PM, Oliveberg M (2005) Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants. Proc Natl Acad Sci USA 102:9754-9759.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9754-9759
-
-
Lindberg, M.J.1
Bystrom, R.2
Boknas, N.3
Andersen, P.M.4
Oliveberg, M.5
-
9
-
-
34547120448
-
Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins
-
Sandelin E, Nordlund A, Andersen PM, Marklund SS, Oliveberg M (2007) Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins. J Biol Chem 282:21230-21236.
-
(2007)
J Biol Chem
, vol.282
, pp. 21230-21236
-
-
Sandelin, E.1
Nordlund, A.2
Andersen, P.M.3
Marklund, S.S.4
Oliveberg, M.5
-
10
-
-
29444444251
-
How evolutionary pressure against protein aggregation shaped chaperone specificity
-
Rousseau F, Serrano L, Schymkowitz JW (2006) How evolutionary pressure against protein aggregation shaped chaperone specificity. J Mol Biol 355:1037-1047.
-
(2006)
J Mol Biol
, vol.355
, pp. 1037-1047
-
-
Rousseau, F.1
Serrano, L.2
Schymkowitz, J.W.3
-
12
-
-
34948850962
-
Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1
-
Niwa J, et al. (2007) Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1. J Biol Chem 282:28087-28095.
-
(2007)
J Biol Chem
, vol.282
, pp. 28087-28095
-
-
Niwa, J.1
-
13
-
-
31544467869
-
Disulfide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models
-
Jonsson PA, et al. (2006) Disulfide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models. Brain 129:451-464.
-
(2006)
Brain
, vol.129
, pp. 451-464
-
-
Jonsson, P.A.1
-
14
-
-
35348874857
-
Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models
-
Zetterstrom P, et al. (2007) Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models. Proc Natl Acad Sci USA 104:14157-14162.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14157-14162
-
-
Zetterstrom, P.1
-
15
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
-
Estevez AG, et al. (1999) Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science 286:2498-2500.
-
(1999)
Science
, vol.286
, pp. 2498-2500
-
-
Estevez, A.G.1
-
17
-
-
34248190279
-
Aβ oligomers - a decade of discovery
-
Walsh DM, Selkoe DJ (2007) Aβ oligomers - a decade of discovery. J Neurochem 101:1172-1184.
-
(2007)
J Neurochem
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
18
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, et al. (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14:837-842.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
-
19
-
-
1942473120
-
Transient formation of nano-crystalline structures during fibrillation of an Aβ-like peptide
-
Otzen DE, Oliveberg M (2004) Transient formation of nano-crystalline structures during fibrillation of an Aβ-like peptide. Protein Sci 13:1417-1421.
-
(2004)
Protein Sci
, vol.13
, pp. 1417-1421
-
-
Otzen, D.E.1
Oliveberg, M.2
-
20
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E, Bieschke J, Perciavalle RM, Kelly JW, Dillin A (2006) Opposing activities protect against age-onset proteotoxicity. Science 313:1604-1610.
-
(2006)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
|