메뉴 건너뛰기




Volumn 6, Issue 12, 2008, Pages 1841-1851

DNA methylation represses IFN-γ-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; GENOMIC DNA; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; METHYL CPG BINDING PROTEIN; PROTEIN INHIBITOR OF ACTIVATED STAT; RECOMBINANT GAMMA INTERFERON; STAT1 PROTEIN;

EID: 57749097557     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0280     Document Type: Article
Times cited : (49)

References (51)
  • 1
    • 0034602764 scopus 로고    scopus 로고
    • IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages
    • Contursi C, Wang IM, Gabriele L, et al. IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages. Proc Natl Acad Sci U S A 2000;97:91-6.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 91-96
    • Contursi, C.1    Wang, I.M.2    Gabriele, L.3
  • 2
    • 16044369709 scopus 로고    scopus 로고
    • Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
    • Holtschke T, Lohler J, Kanno Y, et al. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 1996;87:307-17.
    • (1996) Cell , vol.87 , pp. 307-317
    • Holtschke, T.1    Lohler, J.2    Kanno, Y.3
  • 3
    • 34248230089 scopus 로고    scopus 로고
    • Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells
    • Yang D, Thangaraju M, Greeneltch K, et al. Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Res 2007;67:3301-9.
    • (2007) Cancer Res , vol.67 , pp. 3301-3309
    • Yang, D.1    Thangaraju, M.2    Greeneltch, K.3
  • 4
    • 35948988088 scopus 로고    scopus 로고
    • Host immunosurveillance controls tumor growth via IFN regulatory factor-8 dependent mechanisms
    • Greeneltch KM, Schneider M, Steinberg SM, et al. Host immunosurveillance controls tumor growth via IFN regulatory factor-8 dependent mechanisms. Cancer Res 2007;67:10406-16.
    • (2007) Cancer Res , vol.67 , pp. 10406-10416
    • Greeneltch, K.M.1    Schneider, M.2    Steinberg, S.M.3
  • 5
    • 0033517157 scopus 로고    scopus 로고
    • Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein
    • Gabriele L, Phung J, Fukumoto J, et al. Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein. J Exp Med 1999;190:411-21.
    • (1999) J Exp Med , vol.190 , pp. 411-421
    • Gabriele, L.1    Phung, J.2    Fukumoto, J.3
  • 6
    • 33750502662 scopus 로고    scopus 로고
    • Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease
    • Middleton MK, Zukas AM, Rubinstein T, et al. Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease. J Exp Med 2006;203:2529-40.
    • (2006) J Exp Med , vol.203 , pp. 2529-2540
    • Middleton, M.K.1    Zukas, A.M.2    Rubinstein, T.3
  • 7
    • 0031964844 scopus 로고    scopus 로고
    • Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias
    • Schmidt M, Nagel S, Proba J, et al. Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias. Blood 1998;91:22-9.
    • (1998) Blood , vol.91 , pp. 22-29
    • Schmidt, M.1    Nagel, S.2    Proba, J.3
  • 8
    • 0038618874 scopus 로고    scopus 로고
    • Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-γ
    • Liu K, Abrams SI. Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-γ. J Immunol 2003;170:6329-37.
    • (2003) J Immunol , vol.170 , pp. 6329-6337
    • Liu, K.1    Abrams, S.I.2
  • 9
    • 51349131172 scopus 로고    scopus 로고
    • IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression
    • Yang D, Thangaraju M, Browning DD, et al. IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression. J Immunol 2007;179:4775-82.
    • (2007) J Immunol , vol.179 , pp. 4775-4782
    • Yang, D.1    Thangaraju, M.2    Browning, D.D.3
  • 10
    • 33745522118 scopus 로고    scopus 로고
    • Interferon-γ induces regression of epithelial cell carcinoma: Critical roles of IRF-1 and ICSBP transcription factors
    • Egwuagu CE, Li W, Yu CR, et al. Interferon-γ induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors. Oncogene 2006;25:3670-9.
    • (2006) Oncogene , vol.25 , pp. 3670-3679
    • Egwuagu, C.E.1    Li, W.2    Yu, C.R.3
  • 11
    • 51349083104 scopus 로고    scopus 로고
    • Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas
    • Lee KY, Geng H, Ng KM, et al. Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. Oncogene 2008;27:5267-76.
    • (2008) Oncogene , vol.27 , pp. 5267-5276
    • Lee, K.Y.1    Geng, H.2    Ng, K.M.3
  • 12
    • 30344462965 scopus 로고    scopus 로고
    • Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex
    • Kanno Y, Levi BZ, Tamura T, Ozato K. Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex. J Interferon Cytokine Res 2005;25:770-9.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 770-779
    • Kanno, Y.1    Levi, B.Z.2    Tamura, T.3    Ozato, K.4
  • 13
    • 0027159217 scopus 로고
    • The genomic structure of the murine ICSBP gene reveals the presence of the γ interferon-responsive element, to which an ISGF3 α subunit (or similar) molecule binds
    • Kanno Y, Kozak CA, Schindler C, et al. The genomic structure of the murine ICSBP gene reveals the presence of the γ interferon-responsive element, to which an ISGF3 α subunit (or similar) molecule binds. Mol Cell Biol 1993;13:3951-63.
    • (1993) Mol Cell Biol , vol.13 , pp. 3951-3963
    • Kanno, Y.1    Kozak, C.A.2    Schindler, C.3
  • 14
    • 0026661047 scopus 로고
    • Distribution of interferon-γ receptor in human tissues
    • Valente G, Ozmen L, Novelli F, et al. Distribution of interferon-γ receptor in human tissues. Eur J Immunol 1992;22:2403-12.
    • (1992) Eur J Immunol , vol.22 , pp. 2403-2412
    • Valente, G.1    Ozmen, L.2    Novelli, F.3
  • 15
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE, Jr., Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-21.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 16
    • 0030046753 scopus 로고    scopus 로고
    • Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996;84:331-4.
    • Ihle JN. STATs: signal transducers and activators of transcription. Cell 1996;84:331-4.
  • 17
    • 0030889207 scopus 로고    scopus 로고
    • The IFN γ receptor: A paradigm for cytokine receptor signaling
    • Bach EA, Aguet M, Schreiber RD. The IFN γ receptor: a paradigm for cytokine receptor signaling. Annu Rev Immunol 1997;15:563-91.
    • (1997) Annu Rev Immunol , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 18
    • 0030936627 scopus 로고    scopus 로고
    • GAS elements: A few nucleotides with a major impact on cytokine-induced gene expression
    • Decker T, Kovarik P, Meinke A. GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression. J Interferon Cytokine Res 1997;17:121-34.
    • (1997) J Interferon Cytokine Res , vol.17 , pp. 121-134
    • Decker, T.1    Kovarik, P.2    Meinke, A.3
  • 19
    • 18344390653 scopus 로고    scopus 로고
    • DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
    • Rhee I, Bachman KE, Park BH, et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002;416:552-6.
    • (2002) Nature , vol.416 , pp. 552-556
    • Rhee, I.1    Bachman, K.E.2    Park, B.H.3
  • 21
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006;38:787-93.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3
  • 22
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006;6:107-16.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 23
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD. DNA methylation and human disease. Nat Rev Genet 2005;6:597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 24
    • 34250813682 scopus 로고    scopus 로고
    • Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas
    • Dawson DW, Hong JS, Shen RR, et al. Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene 2007;26:4243-52.
    • (2007) Oncogene , vol.26 , pp. 4243-4252
    • Dawson, D.W.1    Hong, J.S.2    Shen, R.R.3
  • 25
    • 34347218944 scopus 로고    scopus 로고
    • Abnormal DNA methylation, epigenetics, and prostate cancer
    • Nelson WG, Yegnasubramanian S, Agoston AT, et al. Abnormal DNA methylation, epigenetics, and prostate cancer. Front Biosci 2007;12:4254-66.
    • (2007) Front Biosci , vol.12 , pp. 4254-4266
    • Nelson, W.G.1    Yegnasubramanian, S.2    Agoston, A.T.3
  • 26
    • 8544226964 scopus 로고    scopus 로고
    • Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer
    • Leu YW, Yan PS, Fan M, et al. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res 2004;64:8184-92.
    • (2004) Cancer Res , vol.64 , pp. 8184-8192
    • Leu, Y.W.1    Yan, P.S.2    Fan, M.3
  • 27
    • 33847373449 scopus 로고    scopus 로고
    • The role of DNA methylation in the development and progression of lung adenocarcinoma
    • Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers 2007;23:5-30.
    • (2007) Dis Markers , vol.23 , pp. 5-30
    • Kerr, K.M.1    Galler, J.S.2    Hagen, J.A.3    Laird, P.W.4    Laird-Offringa, I.A.5
  • 28
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression - belts, braces, and chromatin
    • Bird AP, Wolffe AP. Methylation-induced repression - belts, braces, and chromatin. Cell 1999;99:451-4.
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 29
    • 0032169599 scopus 로고    scopus 로고
    • Inhibition of Stat1-mediated gene activation by PIAS1
    • Liu B, Liao J, Rao X, et al. Inhibition of Stat1-mediated gene activation by PIAS1. Proc Natl Acad Sci U S A 1998;95:10626-31.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10626-10631
    • Liu, B.1    Liao, J.2    Rao, X.3
  • 30
    • 4644367257 scopus 로고    scopus 로고
    • PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity
    • Liu B, Mink S, Wong KA, et al. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat Immunol 2004;5:891-8.
    • (2004) Nat Immunol , vol.5 , pp. 891-898
    • Liu, B.1    Mink, S.2    Wong, K.A.3
  • 31
    • 0041529514 scopus 로고    scopus 로고
    • SUMO modification of STAT1and its role in PIAS-mediated inhibition of gene activation
    • Rogers RS, Horvath CM, Matunis MJ. SUMO modification of STAT1and its role in PIAS-mediated inhibition of gene activation. J Biol Chem 2003;278:30091-7.
    • (2003) J Biol Chem , vol.278 , pp. 30091-30097
    • Rogers, R.S.1    Horvath, C.M.2    Matunis, M.J.3
  • 32
    • 33751099563 scopus 로고    scopus 로고
    • Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins
    • Lyst MJ, Nan X, Stancheva I. Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins. EMBO J 2006;25:5317-28.
    • (2006) EMBO J , vol.25 , pp. 5317-5328
    • Lyst, M.J.1    Nan, X.2    Stancheva, I.3
  • 33
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003;3:253-66.
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 34
    • 0037688237 scopus 로고    scopus 로고
    • Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma
    • Petak I, Danam RP, Tillman DM, et al. Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma. Cell Death Differ 2003;10:211-7.
    • (2003) Cell Death Differ , vol.10 , pp. 211-217
    • Petak, I.1    Danam, R.P.2    Tillman, D.M.3
  • 35
    • 13444271002 scopus 로고    scopus 로고
    • Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis
    • Chen J, Rocken C, Lofton-Day C, et al. Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis. Carcinogenesis 2005;26:37-43.
    • (2005) Carcinogenesis , vol.26 , pp. 37-43
    • Chen, J.1    Rocken, C.2    Lofton-Day, C.3
  • 36
    • 33750701826 scopus 로고    scopus 로고
    • Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas
    • Ebert MP, Model F, Mooney S, et al. Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas. Gastroenterology 2006;131:1418-30.
    • (2006) Gastroenterology , vol.131 , pp. 1418-1430
    • Ebert, M.P.1    Model, F.2    Mooney, S.3
  • 37
    • 33747889966 scopus 로고    scopus 로고
    • Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
    • Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 2006;66:7490-501.
    • (2006) Cancer Res , vol.66 , pp. 7490-7501
    • Kim, T.Y.1    Zhong, S.2    Fields, C.R.3    Kim, J.H.4    Robertson, K.D.5
  • 38
    • 27144499187 scopus 로고    scopus 로고
    • Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer
    • Chan MW, Wei SH, Wen P, et al. Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer. Clin Cancer Res 2005;11:7376-83.
    • (2005) Clin Cancer Res , vol.11 , pp. 7376-7383
    • Chan, M.W.1    Wei, S.H.2    Wen, P.3
  • 39
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem 2005;74:481-514.
    • (2005) Annu Rev Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 40
    • 0141958153 scopus 로고    scopus 로고
    • Exposure of human primary colon carcinoma cells to anti-Fas interactions influences the emergence of pre-existing Fas-resistant metastatic subpopulations
    • Liu K, McDuffie E, Abrams SI. Exposure of human primary colon carcinoma cells to anti-Fas interactions influences the emergence of pre-existing Fas-resistant metastatic subpopulations. J Immunol 2003;171:4164-74.
    • (2003) J Immunol , vol.171 , pp. 4164-4174
    • Liu, K.1    McDuffie, E.2    Abrams, S.I.3
  • 41
    • 2942574538 scopus 로고    scopus 로고
    • Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
    • Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H, Fodstad O. Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur J Cancer 2004;40:1593-8.
    • (2004) Eur J Cancer , vol.40 , pp. 1593-1598
    • Flatmark, K.1    Maelandsmo, G.M.2    Martinsen, M.3    Rasmussen, H.4    Fodstad, O.5
  • 42
    • 34247876271 scopus 로고    scopus 로고
    • Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites
    • Cespedes MV, Espina C, Garcia-Cabezas MA, et al. Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites. Am J Pathol 2007;170:1077-85.
    • (2007) Am J Pathol , vol.170 , pp. 1077-1085
    • Cespedes, M.V.1    Espina, C.2    Garcia-Cabezas, M.A.3
  • 43
    • 0023818612 scopus 로고
    • Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines
    • Boyd D, Florent G, Kim P, Brattain M. Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. Cancer Res 1988;48:3112-6.
    • (1988) Cancer Res , vol.48 , pp. 3112-3116
    • Boyd, D.1    Florent, G.2    Kim, P.3    Brattain, M.4
  • 44
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate PH, Bird AP. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 1993;3:226-31.
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 45
    • 0025975985 scopus 로고
    • DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
    • Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 1991;64:1123-34.
    • (1991) Cell , vol.64 , pp. 1123-1134
    • Boyes, J.1    Bird, A.2
  • 46
    • 0023387702 scopus 로고
    • Site specific demethylation in the promoter of human γ-globin gene does not alleviate methylation mediated suppression
    • Murray EJ, Grosveld F. Site specific demethylation in the promoter of human γ-globin gene does not alleviate methylation mediated suppression. EMBO J 1987;6:2329-35.
    • (1987) EMBO J , vol.6 , pp. 2329-2335
    • Murray, E.J.1    Grosveld, F.2
  • 47
    • 33748298837 scopus 로고    scopus 로고
    • MBD family proteins: Reading the epigenetic code
    • Fatemi M, Wade PA. MBD family proteins: reading the epigenetic code. J Cell Sci 2006;119:3033-7.
    • (2006) J Cell Sci , vol.119 , pp. 3033-3037
    • Fatemi, M.1    Wade, P.A.2
  • 48
    • 36849012240 scopus 로고    scopus 로고
    • Downregulation of IFN-γR in association with loss of Fas function is linked to tumor progression
    • Yang D, Stewart TJ, Smith KK, Georgi D, Abrams SI, Liu K. Downregulation of IFN-γR in association with loss of Fas function is linked to tumor progression. Int J Cancer 2008;122:350-62.
    • (2008) Int J Cancer , vol.122 , pp. 350-362
    • Yang, D.1    Stewart, T.J.2    Smith, K.K.3    Georgi, D.4    Abrams, S.I.5    Liu, K.6
  • 49
    • 34548863369 scopus 로고    scopus 로고
    • Targeting lymphotoxin h receptor with tumor-specific T lymphocytes for tumor regression
    • Yang D, Ud Din N, Browning DD, Abrams SI, Liu K. Targeting lymphotoxin h receptor with tumor-specific T lymphocytes for tumor regression. Clin Cancer Res 2007;13:5202-10.
    • (2007) Clin Cancer Res , vol.13 , pp. 5202-5210
    • Yang, D.1    Ud Din, N.2    Browning, D.D.3    Abrams, S.I.4    Liu, K.5
  • 51
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 1991;19:2499.
    • (1991) Nucleic Acids Res , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.