Aurora A is essential for early embryonic development and tumor suppression

Journal of Biological Chemistry

Volumn 283, Issue 46, 2008, Pages 31785-31790

  Lu, Lin Yu ^a   Wood, Jamie L ^b,c   Ye, Lin ^a   Minter Dykhouse, Katherine ^c   Saunders, Thomas L ^a   Yu, Xiaochun ^a   Chen, Junjie ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLIFICATION; CELL CULTURE; FIBROBLASTS; GENE EXPRESSION; PROBABILITY DENSITY FUNCTION; TUMORS;

ANEUPLOIDY; AURORA KINASES; CANCER THERAPIES; CLINICAL TRIALS; CRITICAL FUNCTIONS; EMBRYONIC DEVELOPMENTS; GENE AMPLIFICATIONS; GENOMIC STABILITIES; HETEROZYGOSITY; IN PHASE; KNOCK OUTS; MOUSE EMBRYONIC FIBROBLASTS; OVEREXPRESSION; PHYSIOLOGICAL FUNCTIONS; PROGNOSTIC MARKERS; SIDE EFFECTS; SPECIFIC INHIBITORS; SPINDLE ASSEMBLIES; TUMOR SUPPRESSIONS; TUMOR SUPPRESSORS; TUMORIGENESIS; WILD TYPES;

FUNCTIONS;

AURORA A KINASE; CYCLOPROPANECARBOXYLIC ACID [4 [4 (4 METHYL 1 PIPERAZINYL) 6 (5 METHYL 2H PYRAZOL 3 YLAMINO) 2 PYRIMIDINYLTHIO]PHENYL]AMIDE;

ANEUPLOIDY; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CANCER THERAPY; CELL CYCLE PROGRESSION; CELL MATURATION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FIBROBLAST; GENOMIC INSTABILITY; HETEROZYGOSITY; HETEROZYGOTE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANEUPLOIDY; ANIMALS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; MICE, KNOCKOUT; MITOSIS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; TIME FACTORS;

MUS;

EID: 57649119787     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805880200     Document Type: Article

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