Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism

American Journal of Physiology - Endocrinology and Metabolism

Volumn 295, Issue 6, 2008, Pages

  Van Straten, E M E ^a   Huijkman, N C A ^a   Baller, J F W ^a   Kuipers, F ^a   Plosch T ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Adenosine 5 triphosphate binding cassette transporter; Liver X receptor; Nuclear receptors

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; CELL NUCLEUS RECEPTOR; CHOLESTEROL; FATTY ACID; HIGH DENSITY LIPOPROTEIN; INTERMEDIATE DENSITY LIPOPROTEIN; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; LOW DENSITY LIPOPROTEIN; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; VERY LOW DENSITY LIPOPROTEIN;

ABCA1 GENE; ABCG5 GENE; ABCG8 GENE; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; FATTY ACID METABOLISM; FEMALE; FETUS; FETUS DEVELOPMENT; GENE; HOMEOSTASIS; LIPID DIET; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REGULATORY MECHANISM;

ANIMALS; ANIMALS, NEWBORN; ANTICHOLESTEREMIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; DIET, ATHEROGENIC; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYDROCARBONS, FLUORINATED; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SULFONAMIDES;

EID: 57549112069     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90597.2008     Document Type: Article

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