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Volumn 1247, Issue , 2009, Pages 28-37

EUK-207, a superoxide dismutase/catalase mimetic, is neuroprotective against oxygen/glucose deprivation-induced neuronal death in cultured hippocampal slices

Author keywords

Apoptosis; Cultured hippocampal slice; EUK 207; Ischemia; Lipid peroxidation; Oxygen glucose deprivation; Reactive oxygen species

Indexed keywords

APOPTOSIS INDUCING FACTOR; CYTOCHROME C; EUK 207; FLUORESCENT DYE; GLUCOSE; LACTATE DEHYDROGENASE; NEUROPROTECTIVE AGENT; OXYGEN; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 57549097250     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.016     Document Type: Article
Times cited : (14)

References (50)
  • 1
    • 33846818524 scopus 로고    scopus 로고
    • Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
    • Abramov A.Y., Scorziello A., and Duchen M.R. Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J. Neurosci. 27 (2007) 1129-1138
    • (2007) J. Neurosci. , vol.27 , pp. 1129-1138
    • Abramov, A.Y.1    Scorziello, A.2    Duchen, M.R.3
  • 2
    • 0031911994 scopus 로고    scopus 로고
    • Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury
    • Baker K., Marcus C.B., Huffman K., Kruk H., Malfroy B., and Doctrow S.R. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J. Pharmacol. Exp. Ther. 284 (1998) 215-221
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 215-221
    • Baker, K.1    Marcus, C.B.2    Huffman, K.3    Kruk, H.4    Malfroy, B.5    Doctrow, S.R.6
  • 3
    • 0034739736 scopus 로고    scopus 로고
    • Mechanisms underlying hypoxia-induced neuronal apoptosis
    • Banasiak K.J., Xia Y., and Haddad G.G. Mechanisms underlying hypoxia-induced neuronal apoptosis. Prog. Neurobiol. 62 (2000) 215-249
    • (2000) Prog. Neurobiol. , vol.62 , pp. 215-249
    • Banasiak, K.J.1    Xia, Y.2    Haddad, G.G.3
  • 4
    • 33644872102 scopus 로고    scopus 로고
    • The oxidation of 2′,7′-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?
    • Bonini M.G., Rota C., Tomasi A., and Mason R.P. The oxidation of 2′,7′-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?. Free Radic. Biol. Med. 40 (2006) 968-975
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 968-975
    • Bonini, M.G.1    Rota, C.2    Tomasi, A.3    Mason, R.P.4
  • 5
    • 0024410139 scopus 로고
    • Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats
    • Bromont C., Marie C., and Bralet J. Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats. Stroke 20 (1989) 918-924
    • (1989) Stroke , vol.20 , pp. 918-924
    • Bromont, C.1    Marie, C.2    Bralet, J.3
  • 6
    • 0029064034 scopus 로고
    • Development of kainic acid and N-methyl-d-aspartic acid toxicity in organotypic hippocampal cultures
    • Bruce A.J., Sakhi S., Schreiber S.S., and Baudry M. Development of kainic acid and N-methyl-d-aspartic acid toxicity in organotypic hippocampal cultures. Exp. Neurol. 132 (1995) 209-219
    • (1995) Exp. Neurol. , vol.132 , pp. 209-219
    • Bruce, A.J.1    Sakhi, S.2    Schreiber, S.S.3    Baudry, M.4
  • 8
    • 0141925705 scopus 로고    scopus 로고
    • Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation
    • Cao G., Clark R.S., Pei W., Yin W., Zhang F., Sun F.Y., Graham S.H., and Chen J. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J. Cereb. Blood Flow Metab. 23 (2003) 1137-1150
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1137-1150
    • Cao, G.1    Clark, R.S.2    Pei, W.3    Yin, W.4    Zhang, F.5    Sun, F.Y.6    Graham, S.H.7    Chen, J.8
  • 10
    • 57549108968 scopus 로고    scopus 로고
    • Clausen, A., Doctrow, S., Baudry, M., in press. Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase/catalase mimetics in aged mice. Neurobiol. Aging (Electronic publication ahead of print).
    • Clausen, A., Doctrow, S., Baudry, M., in press. Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase/catalase mimetics in aged mice. Neurobiol. Aging (Electronic publication ahead of print).
  • 14
    • 0029286606 scopus 로고
    • Development of identified neuronal types and of specific synaptic connections in slice cultures of rat hippocampus
    • Frotscher M., Zafirov S., and Heimrich B. Development of identified neuronal types and of specific synaptic connections in slice cultures of rat hippocampus. Prog. Neurobiol. 45 (1995) 143-164
    • (1995) Prog. Neurobiol. , vol.45 , pp. 143-164
    • Frotscher, M.1    Zafirov, S.2    Heimrich, B.3
  • 16
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 (1998) 1309-1312
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 17
    • 33744501301 scopus 로고    scopus 로고
    • The role of oxidative stress in noise-induced hearing loss
    • Henderson D., Bielefeld E.C., Harris K.C., and Hu B.H. The role of oxidative stress in noise-induced hearing loss. Ear Hear. 27 (2006) 1-19
    • (2006) Ear Hear. , vol.27 , pp. 1-19
    • Henderson, D.1    Bielefeld, E.C.2    Harris, K.C.3    Hu, B.H.4
  • 18
    • 0035947221 scopus 로고    scopus 로고
    • Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model
    • Jung C., Rong Y., Doctrow S., Baudry M., Malfroy B., and Xu Z. Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Neurosci. Lett. 304 (2001) 157-160
    • (2001) Neurosci. Lett. , vol.304 , pp. 157-160
    • Jung, C.1    Rong, Y.2    Doctrow, S.3    Baudry, M.4    Malfroy, B.5    Xu, Z.6
  • 20
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • Koh J.Y., and Choi D.W. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods 20 (1987) 83-90
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.Y.1    Choi, D.W.2
  • 21
    • 17844385791 scopus 로고    scopus 로고
    • Interactions between Alzheimer's disease and cerebral ischemia-focus on inflammation
    • Koistinaho M., and Koistinaho J. Interactions between Alzheimer's disease and cerebral ischemia-focus on inflammation. Brain Res. Brain Res. Rev. 48 (2005) 240-250
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , pp. 240-250
    • Koistinaho, M.1    Koistinaho, J.2
  • 22
    • 17144434775 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke
    • Komjati K., Mabley J.G., Virag L., Southan G.J., Salzman A.L., and Szabo C. Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke. Int. J. Mol. Med. 13 (2004) 373-382
    • (2004) Int. J. Mol. Med. , vol.13 , pp. 373-382
    • Komjati, K.1    Mabley, J.G.2    Virag, L.3    Southan, G.J.4    Salzman, A.L.5    Szabo, C.6
  • 23
    • 0032861177 scopus 로고    scopus 로고
    • A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence
    • Laake J.H., Haug F.M., Wieloch T., and Ottersen O.P. A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence. Brain Res. Brain Res. Protoc. 4 (1999) 173-184
    • (1999) Brain Res. Brain Res. Protoc. , vol.4 , pp. 173-184
    • Laake, J.H.1    Haug, F.M.2    Wieloch, T.3    Ottersen, O.P.4
  • 24
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91 (1997) 479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 25
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol Rev. 79 (1999) 1431-1568
    • (1999) Physiol Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 26
    • 0038491473 scopus 로고    scopus 로고
    • Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics
    • Liu R., Liu I.Y., Bi X., Thompson R.F., Doctrow S.R., Malfroy B., and Baudry M. Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 8526-8531
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 8526-8531
    • Liu, R.1    Liu, I.Y.2    Bi, X.3    Thompson, R.F.4    Doctrow, S.R.5    Malfroy, B.6    Baudry, M.7
  • 27
    • 0344076349 scopus 로고    scopus 로고
    • Photoreduction of the fluorescent dye 2′-7′-dichlorofluorescein: a spin trapping and direct electron spin resonance study with implications for oxidative stress measurements
    • Marchesi E., Rota C., Fann Y.C., Chignell C.F., and Mason R.P. Photoreduction of the fluorescent dye 2′-7′-dichlorofluorescein: a spin trapping and direct electron spin resonance study with implications for oxidative stress measurements. Free Radic. Biol. Med. 26 (1999) 148-161
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 148-161
    • Marchesi, E.1    Rota, C.2    Fann, Y.C.3    Chignell, C.F.4    Mason, R.P.5
  • 28
    • 33646102911 scopus 로고    scopus 로고
    • Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemia
    • McGowan J.E., Chen L., Gao D., Trush M., and Wei C. Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemia. Neurosci. Lett. 399 (2006) 111-114
    • (2006) Neurosci. Lett. , vol.399 , pp. 111-114
    • McGowan, J.E.1    Chen, L.2    Gao, D.3    Trush, M.4    Wei, C.5
  • 30
    • 0035503501 scopus 로고    scopus 로고
    • Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
    • Melov S., Doctrow S.R., Schneider J.A., Haberson J., Patel M., Coskun P.E., Huffman K., Wallace D.C., and Malfroy B. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J. Neurosci. 21 (2001) 8348-8353
    • (2001) J. Neurosci. , vol.21 , pp. 8348-8353
    • Melov, S.1    Doctrow, S.R.2    Schneider, J.A.3    Haberson, J.4    Patel, M.5    Coskun, P.E.6    Huffman, K.7    Wallace, D.C.8    Malfroy, B.9
  • 31
    • 27544474355 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain and free radical generation in stroke
    • Moro M.A., Almeida A., Bolanos J.P., and Lizasoain I. Mitochondrial respiratory chain and free radical generation in stroke. Free Radic. Biol. Med. 39 (2005) 1291-1304
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 1291-1304
    • Moro, M.A.1    Almeida, A.2    Bolanos, J.P.3    Lizasoain, I.4
  • 32
    • 0034739448 scopus 로고    scopus 로고
    • Phospholipase A(2)s and lipid peroxidation
    • Nigam S., and Schewe T. Phospholipase A(2)s and lipid peroxidation. Biochim. Biophys. Acta 1488 (2000) 167-181
    • (2000) Biochim. Biophys. Acta , vol.1488 , pp. 167-181
    • Nigam, S.1    Schewe, T.2
  • 34
    • 0025309904 scopus 로고
    • Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain
    • Oliver C.N., Starke-Reed P.E., Stadtman E.R., Liu G.J., Carney J.M., and Floyd R.A. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 5144-5147
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 5144-5147
    • Oliver, C.N.1    Starke-Reed, P.E.2    Stadtman, E.R.3    Liu, G.J.4    Carney, J.M.5    Floyd, R.A.6
  • 36
    • 0030060186 scopus 로고    scopus 로고
    • Mitochondrial generation of reactive oxygen species after brain ischemia in the rat
    • Piantadosi C.A., and Zhang J. Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 27 (1996) 327-331
    • (1996) Stroke , vol.27 , pp. 327-331
    • Piantadosi, C.A.1    Zhang, J.2
  • 37
    • 0034722098 scopus 로고    scopus 로고
    • Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons
    • Pong K., Doctrow S.R., and Baudry M. Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons. Brain Res. 881 (2000) 182-189
    • (2000) Brain Res. , vol.881 , pp. 182-189
    • Pong, K.1    Doctrow, S.R.2    Baudry, M.3
  • 38
    • 0034853453 scopus 로고    scopus 로고
    • Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons
    • Pong K., Doctrow S.R., Huffman K., Adinolfi C.A., and Baudry M. Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons. Exp. Neurol. 171 (2001) 84-97
    • (2001) Exp. Neurol. , vol.171 , pp. 84-97
    • Pong, K.1    Doctrow, S.R.2    Huffman, K.3    Adinolfi, C.A.4    Baudry, M.5
  • 39
    • 0032409943 scopus 로고    scopus 로고
    • Mechanisms of cell death in hypoxia/reoxygenation injury
    • Saikumar P., Dong Z., Weinberg J.M., and Venkatachalam M.A. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 17 (1998) 3341-3349
    • (1998) Oncogene , vol.17 , pp. 3341-3349
    • Saikumar, P.1    Dong, Z.2    Weinberg, J.M.3    Venkatachalam, M.A.4
  • 40
    • 34249942190 scopus 로고    scopus 로고
    • Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials
    • Savitz S.I., and Fisher M. Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials. Ann. Neurol. 61 (2007) 396-402
    • (2007) Ann. Neurol. , vol.61 , pp. 396-402
    • Savitz, S.I.1    Fisher, M.2
  • 41
    • 34249016295 scopus 로고    scopus 로고
    • Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats
    • Sharma S.S., and Kaundal R.K. Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Neurol. Res. 29 (2007) 304-309
    • (2007) Neurol. Res. , vol.29 , pp. 304-309
    • Sharma, S.S.1    Kaundal, R.K.2
  • 42
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L., Buchs P.A., and Muller D. A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods 37 (1991) 173-182
    • (1991) J. Neurosci. Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 43
    • 0028902855 scopus 로고
    • Quantitative measurement of neuronal degeneration in organotypic hippocampal cultures after combined oxygen/glucose deprivation
    • Strasser U., and Fischer G. Quantitative measurement of neuronal degeneration in organotypic hippocampal cultures after combined oxygen/glucose deprivation. J. Neurosci. Methods 57 (1995) 177-186
    • (1995) J. Neurosci. Methods , vol.57 , pp. 177-186
    • Strasser, U.1    Fischer, G.2
  • 44
    • 0033570503 scopus 로고    scopus 로고
    • Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia
    • Sugawara T., Fujimura M., Morita-Fujimura Y., Kawase M., and Chan P.H. Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. J. Neurosci. 19 (1999) RC39
    • (1999) J. Neurosci. , vol.19
    • Sugawara, T.1    Fujimura, M.2    Morita-Fujimura, Y.3    Kawase, M.4    Chan, P.H.5
  • 47
    • 0037203544 scopus 로고    scopus 로고
    • Cellular and molecular pathways of ischemic neuronal death
    • Won S.J., Kim D.Y., and Gwag B.J. Cellular and molecular pathways of ischemic neuronal death. J. Biochem. Mol. Biol. 35 (2002) 67-86
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 67-86
    • Won, S.J.1    Kim, D.Y.2    Gwag, B.J.3
  • 48
    • 57549116292 scopus 로고    scopus 로고
    • Yu, S., Liu, M., Gu, X., Ding, F., in press. Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation. Cell Mol. Neurobiol (Electronic publication ahead of print).
    • Yu, S., Liu, M., Gu, X., Ding, F., in press. Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation. Cell Mol. Neurobiol (Electronic publication ahead of print).
  • 49
    • 36448982508 scopus 로고    scopus 로고
    • Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus
    • Zhou M., Dominguez R., and Baudry M. Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus. J. Neurochem. 103 (2007) 2212-2223
    • (2007) J. Neurochem. , vol.103 , pp. 2212-2223
    • Zhou, M.1    Dominguez, R.2    Baudry, M.3
  • 50
    • 33747890559 scopus 로고    scopus 로고
    • The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
    • Zipp F., and Aktas O. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci. 29 (2006) 518-527
    • (2006) Trends Neurosci. , vol.29 , pp. 518-527
    • Zipp, F.1    Aktas, O.2


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