Optimization of the oxidative folding reaction and disulfide structure determination of human α-defensin 1, 2, 3 and 5

International Journal of Peptide Research and Therapeutics

Volumn 14, Issue 4, 2008, Pages 341-349

  Kubo, Shigeru ^a   Tanimura, Kyoko ^a   Nishio, Hideki ^a   Chino, Naoyoshi ^a,b   Teshima, Tadashi ^a,b   Kimura, Terutoshi ^a   Nishiuchi, Yuji ^a,b  

^a Peptide Institute Inc   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Antimicrobial peptide; Chemical synthesis; Defensin; Disulfide structure; Edman degradation; Oxidative folding reaction

Indexed keywords

ALPHA DEFENSIN; BUFFER; CYSTINE; DEFENSIN 1; DEFENSIN 2; DEFENSIN 3; DISULFIDE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMAN ALPHA DEFENSIN 5; NATURAL PRODUCT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ESCHERICHIA COLI; HYDROPHOBICITY; NONHUMAN; OXIDATION; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SOLUBILITY;

EID: 57349176077     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-008-9146-z     Document Type: Conference Paper

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