Chemical synthesis of human β-defensin (hBD)-1, -2, -3 and -4: Optimization of the oxidative folding reaction

International Journal of Peptide Research and Therapeutics

Volumn 12, Issue 3, 2006, Pages 203-209

  Chino, Naoyoshi ^a   Kubo, Shigeru ^a   Nishio, Hideki ^a   Nishiuchi, Yuji ^a   Nakazato, Masamitsu ^b   Kimura, Terutoshi ^a  

^a Protein Research Foundation   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Antimicrobial peptide; Chemical synthesis; Defensin; Disulfide structure; Oxidative folding reaction

Indexed keywords

BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; BETA DEFENSIN 4; CARBONYL DERIVATIVE; DISULFIDE;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; CAPILLARY ZONE ELECTROPHORESIS; CONFERENCE PAPER; CONFORMATION; CONTROLLED STUDY; DISULFIDE BOND; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYMATIC DEGRADATION; ESCHERICHIA COLI; HIGH TEMPERATURE; ION EXCHANGE CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; OXIDATION; PROTEIN FOLDING; REACTION ANALYSIS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; TEMPERATURE DEPENDENCE;

EID: 33745865167     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-006-9018-3     Document Type: Conference Paper

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