Antibacterial activities and conformations of synthetic α-defensin HNP-1 and analogs with one, two and three disulfide bridges

Journal of Peptide Research

Volumn 59, Issue 3, 2002, Pages 95-104

  Mandal, M ^a   Nagaraj, R ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Alpha defensins; Analogs; Antibacterial activities; Cytolytic activities; Disulfide bridges; Secondary structure

Indexed keywords

ALPHA DEFENSIN; ANTIINFECTIVE AGENT; DISULFIDE; PROTEIN CY21; PROTEIN CY26; PROTEIN HNP 1; PROTEIN LHNP; PROTEIN LHNP 1'; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BETA SHEET; CHEMOTAXIS; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOLYSIS; DISULFIDE BOND; DRUG CONFORMATION; DRUG OXIDATION; ESCHERICHIA COLI; HEMOLYSIS; HUMAN; HUMAN CELL; LIPID VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PSEUDOMONAS AERUGINOSA; RAT; STAPHYLOCOCCUS AUREUS;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; CYSTINE; DIMETHYL SULFOXIDE; ESCHERICHIA COLI; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PSEUDOMONAS AERUGINOSA; RATS; RATS, WISTAR; SOLUBILITY; SPLEEN; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; WATER;

ANIMALIA; ESCHERICHIA COLI; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0036196119     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.01945.x     Document Type: Article

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