Cytokine- and virus-stimulated airway smooth muscle cells produce IL-11 and other IL-6-type cytokines

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 273, Issue 3 17-3, 1997, Pages

  Elias, Jack A ^a   Wu, Yang ^a   Zheng, Tao ^a   Panettieri, Reynold ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Asthma; Human airway smooth muscle cell; Interleukin 11; Interleukin 6; Leukemia inhibitory factor; Parainfluenza virus; Respiratory syncytial virus

Indexed keywords

INTERLEUKIN 11; INTERLEUKIN 6;

ARTICLE; ASTHMA; BRONCHOSPASM; BRONCHUS MUSCLE; HUMAN; HUMAN CELL; IMMUNOREGULATION; PARAINFLUENZA VIRUS; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT DISEASE;

EID: 0030817706     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.273.3.l648     Document Type: Article

References (46)

1. Alexander, R. H., K. G. Billingsley, M. I. Block, and D. L. Fraker. D-factor/leukaemia inhibitory factor: evidence for its role as a mediator in acute and chronic inflammatory disease. Cytokine 6: 589-596, 1994.
2. Amrani, Y., R. A. J. Panettieri, N. Frossard, and C. Bronner. Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 15: 55-63, 1996.
3. Anonymous. Workshop on airway smooth muscle. Summary of a conference held September 25-27, 1983. Am. Rev. Respir. Dis. 131: 159-162, 1985.
4. Bradding, P., A. E. Redington, and S. T. Holgate. Airway wall remodelling in the pathogenesis of asthma: cytokine expression in the airways. In: Airway Wall Remodelling in Asthma, edited by A. G. Stewart. Boca Raton, FL: CRC, 1997, p. 29-63.
5. Carroll, G. J., M. C. Bell, H. M. Chapman, J. N. Mills, and W. F. Robinson. Leukemia inhibitory factor induces leukocyte infiltration and cartilage proteoglycan degradation in goat joints. J. Interferon Cytokine Res. 15: 567-573, 1995.
6. Colby, T. V., and J. L. Myers. Clinical and histologic spectrum of bronchiolitis obliterans, including bronchiolitis obliterans organizing pneumonia. Semin. Respir. Med. 13: 119-133, 1992.
7. DiCosmo, B. F., G. P. Geba, D. Picarella, J. A. Elias, J. A. Rankin, B. R. Stripp, J. A. Whitsett, and R. A. Flavell. Airway targeted interleukin-6 in transgenic mice: uncoupling of airway inflammation and bronchial hyperreactivity. J. Clin. Invest. 94: 2028-2035, 1994.
8. Du, X. X., and D. A. Williams. Interleukin-11: a multifunctional growth factor derived from the hematopoietic microenvironment. Blood 83: 2023-2030, 1994.
9. Ebina, M., T. Takahashi, T. Chiba, and M. Motomiya. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. Am. Rev. Respir. Dis. 148: 720-726, 1993.
10. Einarsson, O., G. P. Geba, Z. Zhu, M. Landry, and J.A. Elias. Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J. Clin. Invest. 97: 915-924, 1996.
11. Elias, J. A., T. Zheng, O. Einarsson, M. Landry, T. K. Trow, N. Rebert, and J. Panuska. Epithelial interleukin-11: regulation by cytokines, respiratory syncytial virus and retinoic acid. J. Biol. Chem. 169: 22261-22268, 1994.
12. Elias, J. A., T. Zheng, N. L. Whiting, A. Marcovici, and T. K. Trow. Cytokine-cytokine synergy and protein kinase C in the regulation of lung fibroblast leukemia inhibitory factor. Am. J. Physiol. 266 (Lung Cell. Mol. Physiol. 10): L426-L435, 1994.
13. Elias, J. A., T. Zheng, N. L. Whiting, T. K. Trow, W. W. Merrill, R. Zitnik, P. Ray, and E. M. Alderman. Interleukin-1 and transforming growth factor β regulation of fibroblast-derived interleukin-11. J. Immunol. 152: 2421-2429, 1994.
14. Halayko, A. J., and N. L. Stephens. Potential role for phenotypic modulation of bronchial smooth muscle cells in chronic asthma. Can. J. Physiol. Pharmacol. 72: 1448-1457, 1993.
15. Heard, B. E., and S. Hossain. Hyperplasia of bronchial muscle in asthma. J. Pathol. 110: 319-331, 1973.
16. Hilton, D. J. LIF: lots of interesting functions. Trends Biochem. Sci. 17: 72-76, 1992.
17. James, A. J. Relationship between airway wall thickness and airway hyperresponsiveness. In: Airway Wall Remodelling in Asthma, edited by A. G. Stewart. Boca Raton, FL: CRC, 1997, p. 1-27.
18. Lazaar, A. L., S. M. Albelda, J. M. Pilewski, B. Brennan, E. Pure, and R. A. J. Panettieri. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J. Exp. Med. 180: 807-816, 1994.
19. Lazaar, A. L., H. E. Reitz, R. A. J. Panettieri, S. P. Peters, and E. Pure. Antigen receptor-stimulated peripheral blood and bronchoalveolar lavage-derived T cells induce MHC class II and ICAM-1 expression on human airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 16: 38-45, 1997.
20. Lukacs, N. W., S. L. Kunkel, R. Allen, H. L. Evanoff, C. L. Shaklee, J. S. Sherman, M. D. Burdick, and R. M. Strieter. Stimulus and cell-specific expression of C-X-C and C-C chemokines by pulmonary stromal cell populations. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L856-L861, 1995.
21. Maier, R., V. Ganu, and M. Lotz. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases. J. Biol. Chem. 268: 21527-21532, 1993.
22. Murray, A. G., P. Libby, and J. S. Pober. Human vascular smooth muscle cells poorly co-stimulate and actively inhibit allogeneic CD4+ T cell proliferation in vitro. J. Immunol. 154: 151-161, 1995.
23. Musso, T., R. Badolato, D. L. Longo, G. L. Gusella, and L. Varesio. Leukemia inhibitory factor induces interleukin-8 and monocyte chemotactic and activating factor in human monocytes: differential regulation by interferon-gamma. Blood 86: 1961-1967, 1995.
24. Nandurkar, H. H., D. J. Hilton, P. Nathan, T. Willson, N. Nicola, and C. G. Begley. The human IL-11 receptor requires gp130 for signalling: demonstration by molecular cloning of the receptor. Oncogene 12: 585-593, 1996.
25. Newman, W. H., L. M. Zhang, S. K. Leeper-Woodford, and M. R. Castresana. Human blood vessels release tumor necrosis factor-alpha from a smooth muscle cell source. Crit. Care Med. 24: 294-297, 1996.
26. Nogami, M., D. J. Romberger, S. I. Rennard, and M. L. Toews. TGF-β1 modulates β-adrenergic receptor number and function in cultured human tracheal smooth muscle cells. Am. J. Physiol. 266 (Lung Cell. Mol. Physiol. 10): L187-L191, 1994.
27. Panettieri, R. A., R. K. Murray, L. R. Depalo, P. A. Yadvish, and M. I. Kotlikoff. A human airway smooth muscle cell line that retains physiological responsiveness. Am. J. Physiol. 256 (Cell Physiol. 25): C329-C335, 1989.
28. Panettieri, R. A., P. A. Yadvish, A. M. Kelly, N. A. Rubinstein, and M. I. Kotlikoff. Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression. Am. J. Physiol. 259 (Lung Cell. Mol. Physiol. 3): L365-L371, 1990.
29. Panettieri, R. A. J., R. G. Goldie, P. J. Rigby, A. J. Eszterhas, and D. W. Hay. Endothelin-1-induced potentiation of human airway smooth muscle proliferation: an ETA receptor-mediated phenomenon. Br. J. Pharmacol. 118: 191-197, 1996.
30. Panettieri, R. A. J., A. L. Lazaar, E. Pure, and S. M. Albelda. Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion. J. Immunol. 154: 2358-2365, 1995.
31. Perrella, M. A., C. M. Hsieh, W. S. Lee, S. Shieh, J. C. Tsai, and C. Patterson. Arrest of endotoxin-induced hypotension by transforming growth factor betal. Proc. Natl. Acad. Sci. USA 93: 2054-2059, 1996.
32. Poon, M., W. C. Hsu, V. Y. Bogadanov, and M. B. Taubman. Secretion of monocyte chemotactic activity by cultured rat aortic smooth muscle cells in response to PDGF is due predominantly to the induction of JE/MCP-1. Am. J. Pathol. 149: 307-317, 1996.
33. Redlich, A. A., X. Gao, S. Rockwell, M. Kelley, and J. A. Elias. IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury. J. Immunol. 157: 1705-1710, 1996.
34. Roberts, A. B., M. B. Sporn, R. K. Assoian, J. M. Smith, N. S. Roche, L. M. Wakefield, U. I. Heine, L. A. Liotta, V. Falanga, J. H. Kehrl, and A. S. Fauci. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. USA 83: 4167-4171, 1986.
35. Roche, W. R., J. H. Williams, R. Beasley, and S. T. Holgate. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1: 520-524, 1989.
36. Shadiack, A. M., R. P. Hart, C. D. Carlson, and M. G. Jonakait. Interleukin-1 induces substance P in sympathetic ganglia through the induction of leukemia inhibitory factor (LIF). J. Neurosci. 13: 2601-2609, 1993.
37. Shelhamer, J. H., S. J. Levine, T. Wu, D. B. Jacoby, M. A. Kaliner, and S. I. Rennard. Airway inflammation. Ann. Intern. Med. 123: 288-304, 1995.
38. Sousa, A. R., S. J. Lane, J. A. Nakhosteen, T. Yoshimura, T. H. Lee, and R. N. Poston. Increased expression of the monocyte chemoattractant protein-1 in bronchial tissue from asthmatic subjects. Am. J. Respir. Cell Mol. Biol. 10: 142-147, 1994.
39. Tang, W., G. P. Geba, T. Zheng, P. Ray, R. Homer, C. I. Kuhn, R. A. Favell, and J. A. Elias. Targeted expression of IL-11 in the murine airway causes airways obstruction, bronchial remodeling and lymphocytic inflammation. J. Clin. Invest. 98: 2845-2853, 1996.
40. Trepicchio, W. L., M. Bozza, G. Pedneault, and A. J. Dorner. Recombinant human IL-11 attenuates the inflammatory response through downregulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 157: 3627-3634, 1996.
41. Ulich, T. R., M.-J. Fann, P. H. Patterson, J. H. Williams, B. Samal, J. D. Castillo, S. Yin, K. Guo, and D. G. Remick. Intratracheal injection of LPS and cytokines. V. LPS induces expression of LIF and LIF inhibits acute inflammation. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L442-L446, 1994.
42. Villiger, P. M., Y. Geng, and M. Lotz. Induction of cytokine expression by leukemia inhibitory factor. J. Clin. Invest. 91: 1575-1581, 1993.
43. Waring, P., K. Wycherley, D. Cary, N. Nicola, and D. Metcalf. Leukemia inhibitory factor levels are elevated in septic shock and various inflammatory body fluids. J. Clin. Invest. 90: 2031-2037, 1992.
44. Wiggs, B. R., C. Bosken, P. D. Pare, A. James, and J. C. Hogg. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 145: 1251-1258, 1992.
45. Zheng, T., M. Nathanson, and J. A. Elias. Histamine augments cytokine-stimulated interleukin-11 production by human lung fibroblasts. J. Immunol. 153: 4742-4752, 1994.
46. Zitnik, R. J., and J. A. Elias. Interleukin-6 in the lung. In: Lung Biology in Health and Disease, edited by C. E. E. Lenfant. New York: Dekker, 1993, p. 229-280.