Synthesis and cytotoxicity of novel 3-aryl-1-(3′-dibenzylaminomethyl- 4′-hydroxyphenyl)-propenones and related compounds

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 12, 2008, Pages 1675-1681

  Gul, Halise Inci ^a   Yerdelen, Kadir Ozden ^a   Das, Umashankar ^b   Gul, Mustafa ^c   Pandit, Bulbul ^d   Li, Pui Kai ^d   Dimmock, Jonathan Richard ^b  

^a ATATÜRK UNIVERSITY   (Turkey)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c ATATURK UNIVERSITY   (Turkey)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Androgen independent prostate cancer cell line; Chalcone; Cytotoxicity; Dibenzylamine; Mannich base

Indexed keywords

4' HYDROXY 3' DIBENZYLAMINOMETHYLCHALCONE DERIVATIVE; CHALCONE DERIVATIVE; FLUOROURACIL; MANNICH BASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROSCOPY; PKA; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS, ALKYLATING; BENZYL COMPOUNDS; BINDING SITES; CARCINOGENS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLIZATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KETONES; MAGNETIC RESONANCE SPECTROSCOPY; MANNICH BASES; MODELS, MOLECULAR; MUTAGENS; PROPANE; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 57349147068     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.1675     Document Type: Article

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