Cytotoxic and anticonvulsant aryloxyaryl Mannich bases and related compounds

European Journal of Medicinal Chemistry

Volumn 39, Issue 1, 2004, Pages 27-35

  Vashishtha, Sarvesh C ^a   Zello, Gordon A ^a   Nienaber, Kurt H ^a   Balzarini, Jan ^b   De Clercq, Erik ^b   Stables, James P ^c   Dimmock, Jonathan R ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Anticonvulsant activity; Cytotoxicity; Mannich bases; Molecular modelling; Murine toxicity; Structure activity relationships

Indexed keywords

ANTICONVULSIVE AGENT; MANNICH BASE; SOLVENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; ELECTRIC SHOCK; HUMAN; HUMAN CELL; IC 50; MOLECULAR MODEL; MOUSE; NONHUMAN; PROTECTION; STRUCTURE ANALYSIS; SURFACE PROPERTY; T LYMPHOCYTE;

EID: 1342300765     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2003.09.011     Document Type: Article

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