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Volumn 52, Issue 8, 2002, Pages 628-635

Syntheses and stability studies of some Mannich bases of acetophenones and evaluation of their cytotoxicity against Jurkat cells

(3) Gul, Halise Inci a Gul, Mustafa a Erciyas, Ercin a

a ATATÜRK UNIVERSITY (Turkey)

Author keywords

Acetophenone, cytotoxic activity, Mannich bases, stability studies, synthesis; Anticancer drugs

Indexed keywords

ACETOPHENONE DERIVATIVE; FLUOROURACIL; MANNICH BASE; MELPHALAN;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; STRUCTURE ACTIVITY RELATION;

EID: 0036350482 PISSN: 00044172 EISSN: None Source Type: Journal
DOI: 10.1055/s-0031-1299942 Document Type: Article

Times cited : (37)

References (26)

1
- 0025258487
- Evaluation of the cytotoxicity of some Mannich bases of acetophenone against the EMT 6 tumour
- (1990) Pharmazie , vol.45 , pp. 755
- Dimmock, J.R.¹ Erciyas, E.² Raghavan, S.K.³

2
- 0033995992
- Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against renca and jurkat cells
- (2000) Pharm. Acta Helv. , vol.74 , pp. 393
- Gul, H.I.¹ Vepsalainen, J.² Gul, M.³

3
- 0028318455
- Antimicrobial evaluation of some styryl ketone derivatives and related thiol adducts
- (1994) J. Pharm. Sci. , vol.83 , pp. 545
- Erciyas, E.¹ Erkaleli, H.I.² Cosar, G.³

4
- 0035133288
- Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone
- (2001) Arzneim.-Forsch./Drug Res. , vol.51 , Issue.1 , pp. 72
- Gul, H.I.¹ Ojanen, T.² Vepsalainen, J.³

5
- 0014601147
- Action mechanism of antimicrobial beta-amino ketones
- (1969) Pharm. Acta Helv. , vol.44 , pp. 691
- Schoenenberger, H.¹ Bastug, T.² Bindl, L.³

6
- 0024845339
- Synthesis and preliminary study of some ring-substituted arylpropanamines and their quaternary salts
- (1989) Eur. J. Med. Chem. , vol.24 , pp. 591
- Stenlake, J.B.¹ Patrick, G.L.² Sneader, W.E.³

7
- 0023748452
- Evaluation of some azines of aminomethylacetophenones and related quaternary ammonium compounds versus the EMT 6 tumour
- (1988) Pharmazie , vol.43 , pp. 614
- Dimmock, J.R.¹ Erciyas, E.² Kirkpatrick, D.L.³

8
- 0020572601
- Evaluation of some Mannich bases derived from substituted acetophenones against P-388 lymphocytic leukemia and on respiration in isolated rat liver mitochondria
- (1983) J. Pharm. Sci. , vol.72 , pp. 887
- Dimmock, J.R.¹ Shyam, K.² Hamon, N.W.³

9
- 0020565902
- Antileukemic evaluation of some Mannich bases derived from 2-Arylidene-1,3-diketones
- (1983) Eur. J. Med. Chem. Chim. Ther. , vol.18 , pp. 248
- Dimmock, J.R.¹ Raghavan, S.K.² Logan, B.M.³

10
- 0013830187
- Hobby G. L. (ed.), American Society for Microbiology, Bethesda, MD
- (1965) Antimicrobial Agents and Chemotherapy , pp. 165
- Gordon, P.N.¹ Johnston, J.D.² English, A.R.³

11
- 0024556933
- 1-p-chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3-one hydrobromide, a Sulfhydryl-specific compound which reacts irreversibly with protein thiols but reversibly with small molecular weight thiols
- (1989) Anal. Biochem. , vol.177 , pp. 237
- Mutus, B.¹ Wagner, J.D.² Talpas, C.J.³

12
- 0033779768
- Cellular and clinical implications of glutathione
- (2000) Indian J. Exp. Biol. , vol.38 , pp. 625
- Gul, M.¹ Kutay, F.Z.² Temocin, S.³

13
- 0034887801
- Effect of acetophenone derived Mannich bases on cellular glutathione level in jurkat cells: A possible mechanism of action
- (2001) Arzneim.Forsch./Drug Res. , vol.51 , Issue.2 , pp. 679
- Gul, M.¹ Gul, H.I.² Vepsalainen, J.³

14
- 14444281422
- 4-(β-Arylvinyl)-3-(β-arylvinylketo)-1-ethyl-4-piperidinols and related compounds: A novel class of cytotoxic and anticancer agents
- (1998) J. Med. Chem. , vol.41 , pp. 4012
- Dimmock, J.R.¹ Vashishtha, S.C.² Quail, J.W.³

15
- 39149128173
- Synthesis of β-keto bases from aliphatic-aromatic ketones, formaldehyde, and secondary amines
- (1922) Chem. Ber. , vol.55 B , pp. 3510
- Mannich, C.¹ Lammering, D.²

16
- 0000749812
- The reaction of acetophenone with formaldehyde and methylamine hydrochloride
- (1949) J. Org. Chem. , vol.14 , pp. 543
- Plati, J.T.¹ Wenner, W.²

17
- 0024562556
- Synthesis and cytotoxic activity of pyridylthio, pyridylsulfinyl, and pyridylsulfonyl methyl acrylates
- (1989) Drug Des. Delivery , vol.4 , pp. 121
- Phillips, O.A.¹ Nelson, L.A.² Knaus, E.E.³

18
- 0000236445
- 1,3,4-Trisubstituted piperidine derivatives from Mannich bases
- (1949) J. Org. Chem. , vol.14 , pp. 873
- Plati, J.T.¹ Schmidt, R.A.² Wenner, W.³

19
- 0000098420
- Synthesis and study of Mannich bases from 2-Naphtol and primary amines
- (1964) J. Org. Chem. , vol.29 , pp. 407
- Burke, W.J.¹ Nasutavicus, W.A.² Weatherbee, C.³

20
- 4243698715
- (Reval drug and Chemical Co.), 1-Methyl-3-benzoyl-4-hydroxy-4-phenylpiperidine and its halo derivatives. US Patent 3, 308, 445 (C1 424-257), October 29, 1968
- (1969) Chem. Abstr. , vol.70
- Levy, L.¹ McClure, D.A.²

21
- 0000994750
- Neue piperidinderivate aus herzwirksamen beta-aminoketonen
- (1968) Arzneim.-Forsch./Drug Res. , vol.18 , pp. 1265
- Thiele, V.K.¹ Posselt, K.² Von Bebenburg, W.³

22
- 0010201413
- Spatial structure and stereochemistry of synthesis of 1-alkyl-4-phenyl-3-benzoyl-4-piperidinol
- (1966) Zh. Org. Chim. , vol.2 , pp. 1501
- Unkovskii, B.V.¹ Mel'nikova, A.A.² Zaitseva, M.G.³

23
- 0010765012
- Beta-Dimethylaminopropiophenone hydrochloride
- (1943) Org. Syn. Collective , vol.3 , pp. 305
- Maxwell, C.E.¹

24
- 4244046886
- (Hoffmann-La Roche Inc.) 3-Amino-2-aminomethyl-1-phenyl-1-propanols. US Patent 3,058,987, October 16,1962
- (1963) Chem. Abst. , vol.58
- Albrecht, H.A.¹ Plati, J.T.² Wenner, W.³

25
- 0014597617
- Analgetics. II. Relationship between structure and activity of some beta-aminoketones
- (1969) J. Med. Chem. , vol.12 , pp. 994
- Atwal, M.S.¹ Bauer, I.² Dixit, S.N.³

26
- 4243724631
- Fungicidal Aryl and Beta-aminoethyl Ketones. Ital. Patent 637,371, March 29, 1962
- (1964) Chem. Abst. , vol.60
- Plastino, E.¹ Loprieno, N.² Bugian, A.³

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