Antifungal evaluation of bis Mannich bases derived from acetophenones and their corresponding piperidinols and stability studies

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 10, 2002, Pages 1307-1310

  Gul, Halise Inci ^a,c   Ojanen, Tarja ^b   Hänninen, Osmo ^c  

^a ATATÜRK UNIVERSITY   (Turkey)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Acetophenone; Antifungal activity; Dermatophyte; Mannich base

Indexed keywords

ACETOPHENONE DERIVATIVE; AMPHOTERICIN B; MANNICH BASE; PIPERIDINE DERIVATIVE; ANTIFUNGAL AGENT; PIPERIDONE DERIVATIVE;

ALKYLATION; ANTIFUNGAL ACTIVITY; ARTICLE; EVALUATION; MICROSPORUM CANIS; NONHUMAN; TRICHOPHYTON MENTAGROPHYTES; TRICHOPHYTON RUBRUM; TRICHOPHYTON TONSURANS; ARTHRODERMA; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG SCREENING; DRUG STABILITY; GROWTH, DEVELOPMENT AND AGING; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; STATISTICS; YEAST;

ACETOPHENONES; ANTIFUNGAL AGENTS; ARTHRODERMATACEAE; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; MANNICH BASES; MICROBIAL SENSITIVITY TESTS; PIPERIDONES; YEASTS;

EID: 0036782596     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1307     Document Type: Article

References (28)

1. Erciyas E., Erkaleli H. I., Cosar G., J. Pharm. Sci., 83, 545-548 (1994).
2. Gul H. I., Denizci A. A., Erciyas E., Arzaeim.-Forsch./Drug Res., 52, (2002) in press.
3. Gul H. I., Ojanen T., Vepsalainen J., Gul M., Erciyas E., Hanninen O., Arzneim.-Forsch./Drug Res., 51, 72-75 (2001).
4. Manavathu E. K., Vashishtha S. C., Alangaden G. J., Dimmock J. R., Can. J. Microbiol., 44, 74-79 (1998).
5. Medic-Saric M., Maysinger D., Movrin M., Dvorzak I., Chemotherapy, 26, 263-267 (1980).
6. Gul H. I., Gul M., Erciyas E., Arznuim.-Forsch./Drug Res., 52, 628-635 (2002).
7. Gul H. I., Gul M., Hänninen O., Arzneim.-Forsch./Drug Res., 52, (2002) in press.
8. Gul H. I., Vepsalainen J., Gul M., Erciyas E., Hanninen O., Pharm. Acta Helv., 74, 393-398 (2000).
9. el-Merzabani M. M., Kamel M. M., Nabih I., Nasr M., Zayed A., Pharmazie, 31, 485-487 (1976).
10. Siatra-Papastaikoudi T., Tsotinis A., Chinou I., Roussakis C., Farmaco, 49, 221-223 (1994).
11. Atwal M. S., Bauer L., Dixit S. N., Gearien J. E., Megahy M., Morris R., Pokorny C., J. Med. Chem., 12, 994-997 (1969).
12. Koechel D. A., Rankin G. O., J. Med. Chem., 21, 764-769 (1978).
13. Lee C. M., Plattner J. J., Ours C. W., Horrom B. W., Smital J. R., Pernet A. G., Bunnell P. R., El-Masry S. E., Dodge P. W., J. Med. Chem., 27, 1579-1587 (1984).
14. Borenstein M. R., Doukas P. H., J. Pharm. Sci., 76, 300-302 (1987).
15. Dimmock J. R., Jonnalagadda S. S., Phillips O. A., Erciyas E., Shyam K., Semple H. A., J. Pharm. Sci., 81, 436-440 (1992).
16. Gul H. I., Calis U., Vepsalainen J., Arzneim.-Forsch./Drug Res., 52, (2002) in press.
17. Gursoy A., Karali N., Buyuktimkin S., Demirayak S., Ekinci A. C., Ozer H., Farmaco. 51, 437-442 (1996).
18. Gordon P. N., Johnston J. D., English A. R., "Beta-aminoketones as Anti-infective Agents," ed. by Hobby G. L., American Society for Microbiology, Bethesda, 1965.
19. Gul M., Gul H. I., Hanninen O., Toxicol., In Vitro, 16, 107-112 (2002)
20. Gul M., Gul H. I., Vepsalainen J., Erciyas E., Hanninen O., Arzneim.-Forsch./Drug Res., 51, 679-682 (2001).
21. Schoenenberger H., Bastug T., Bindl L., Adam A., Adam D., Petter A., Zwez W., Pharm. Acta Helv., 44, 691-714 (1969).
22. Kupinic M., Medic-Saric M., Movrin M., Maysinger D., J. Pharm. Sci., 68, 459-462 (1979).
23. Espinel-Ingroff A., Pfaller M. A., "Manual of Clinical Microbiology," ed. by Murray P. R., Ed.; American Society Microbiology, Washington, D.C., 1995. pp. 1405-1414.
24. NCCLS., "Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts," Approved Standard M27A, 1997.
25. NCCLS., "Reference Method for Broth Dilution Antifungal Susceptibility Testing of Conidium-Forming Filamentaous Fungi," Proposed Standard M38P, 1998.
26. Fernandez-Torres B., Carrillo A. J., Martin E., Del Palacio A., Moore M. K., Valverde A., Serrano M., Guarro J., Antimicrob. Agents Chemother., 45, 2524-2528 (2001).
27. Dimmock J. R., Patil S. A., Shyam K., Pharmazie. 46, 538-539 (1991).
28. Dimmock J. R., Kumar P., Manavathu E. K., Obedeanu N., Grewal J., Pharmazie, 49, 909-912 (1994).