메뉴 건너뛰기




Volumn 3, Issue 12, 2008, Pages

The N-terminal domain of ERK1 accounts for the functional differences with ERK2

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

EID: 57349141931     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003873     Document Type: Article
Times cited : (42)

References (51)
  • 2
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, et al. (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22: 153-183.
    • (2001) Endocr Rev , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Beers Gibson, T.3    Xu, B.E.4    Karandikar, M.5
  • 4
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
    • Sweatt JD (2001) The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76: 1-10.
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 5
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24: 21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 6
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J (2003) Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3: 11-22.
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 7
    • 0038697566 scopus 로고    scopus 로고
    • Raf proteins and cancer: B-Raf is identified as a mutational target
    • Mercer KE, Pritchard CA (2003) Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 1653: 25-40.
    • (2003) Biochim Biophys Acta , vol.1653 , pp. 25-40
    • Mercer, K.E.1    Pritchard, C.A.2
  • 8
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • Malumbres M, Barbacid M (2003) RAS oncogenes: the first 30 years. Nat Rev Cancer 3: 459-465.
    • (2003) Nat Rev Cancer , vol.3 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 9
    • 34248595035 scopus 로고    scopus 로고
    • Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
    • Owens DM, Keyse SM (2007) Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene 26: 3203-3213.
    • (2007) Oncogene , vol.26 , pp. 3203-3213
    • Owens, D.M.1    Keyse, S.M.2
  • 10
    • 0025823448 scopus 로고
    • ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
    • Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, et al. (1991) ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65: 663-675.
    • (1991) Cell , vol.65 , pp. 663-675
    • Boulton, T.G.1    Nye, S.H.2    Robbins, D.J.3    Ip, N.Y.4    Radziejewska, E.5
  • 11
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG (1995) The MAPK signaling cascade. Faseb J 9: 726-735.
    • (1995) Faseb J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 12
    • 18444381728 scopus 로고    scopus 로고
    • Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory
    • Mazzucchelli C, Vantaggiato C, Ciamei A, Fasano S, Pakhotin P, et al. (2002) Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron 34: 807-820.
    • (2002) Neuron , vol.34 , pp. 807-820
    • Mazzucchelli, C.1    Vantaggiato, C.2    Ciamei, A.3    Fasano, S.4    Pakhotin, P.5
  • 13
    • 17144458301 scopus 로고    scopus 로고
    • Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
    • Pages G, Guerin S, Grall D, Bonino F, Smith A, et al. (1999) Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286: 1374-1377.
    • (1999) Science , vol.286 , pp. 1374-1377
    • Pages, G.1    Guerin, S.2    Grall, D.3    Bonino, F.4    Smith, A.5
  • 14
    • 33845904217 scopus 로고    scopus 로고
    • ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
    • Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, et al. (2006) ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. J Biol 5: 14.
    • (2006) J Biol , vol.5 , pp. 14
    • Vantaggiato, C.1    Formentini, I.2    Bondanza, A.3    Bonini, C.4    Naldini, L.5
  • 15
    • 51649125641 scopus 로고    scopus 로고
    • RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo
    • Bessard A, Fremin C, Ezan F, Fautrel A, Gailhouste L, et al. (2008) RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo. Oncogene 27: 5315-5325.
    • (2008) Oncogene , vol.27 , pp. 5315-5325
    • Bessard, A.1    Fremin, C.2    Ezan, F.3    Fautrel, A.4    Gailhouste, L.5
  • 16
    • 34247358156 scopus 로고    scopus 로고
    • ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes
    • Fremin C, Ezan F, Boisselier P, Bessard A, Pages G, et al. (2007) ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes. Hepatology 45: 1035-1045.
    • (2007) Hepatology , vol.45 , pp. 1035-1045
    • Fremin, C.1    Ezan, F.2    Boisselier, P.3    Bessard, A.4    Pages, G.5
  • 17
    • 0026608787 scopus 로고
    • Nuclear localization and regulation of erk- and rsk-encoded protein kinases
    • Chen RH, Sarnecki C, Blenis J (1992) Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol Cell Biol 12: 915-927.
    • (1992) Mol Cell Biol , vol.12 , pp. 915-927
    • Chen, R.H.1    Sarnecki, C.2    Blenis, J.3
  • 18
    • 0031852068 scopus 로고    scopus 로고
    • Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins
    • Lenormand P, Brondello JM, Brunet A, Pouyssegur J (1998) Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins. J Cell Biol 142: 625-633.
    • (1998) J Cell Biol , vol.142 , pp. 625-633
    • Lenormand, P.1    Brondello, J.M.2    Brunet, A.3    Pouyssegur, J.4
  • 19
    • 0033081066 scopus 로고    scopus 로고
    • Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
    • Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, et al. (1999) Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. Embo J 18: 664-674.
    • (1999) Embo J , vol.18 , pp. 664-674
    • Brunet, A.1    Roux, D.2    Lenormand, P.3    Dowd, S.4    Keyse, S.5
  • 20
    • 0034617204 scopus 로고    scopus 로고
    • Significance of nuclear relocalization of ERK1/2 in reactivation of c-fos transcription and DNA synthesis in senescent fibroblasts
    • Kim K, Nose K, Shibanuma M (2000) Significance of nuclear relocalization of ERK1/2 in reactivation of c-fos transcription and DNA synthesis in senescent fibroblasts. J Biol Chem 275: 20685-20692.
    • (2000) J Biol Chem , vol.275 , pp. 20685-20692
    • Kim, K.1    Nose, K.2    Shibanuma, M.3
  • 21
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S, Paterson H, Kemp P, Marshall CJ (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77: 841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 22
    • 0032558692 scopus 로고    scopus 로고
    • A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation
    • Robinson MJ, Stippec SA, Goldsmith E, White MA, Cobb MH (1998) A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation. Curr Biol 8: 1141-1150.
    • (1998) Curr Biol , vol.8 , pp. 1141-1150
    • Robinson, M.J.1    Stippec, S.A.2    Goldsmith, E.3    White, M.A.4    Cobb, M.H.5
  • 23
    • 8844260411 scopus 로고    scopus 로고
    • Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting
    • Ando R, Mizuno H, Miyawaki A (2004) Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting. Science 306: 1370-1373.
    • (2004) Science , vol.306 , pp. 1370-1373
    • Ando, R.1    Mizuno, H.2    Miyawaki, A.3
  • 24
    • 33845886924 scopus 로고    scopus 로고
    • Dynamic regulation of ERK2 nuclear translocation and mobility in living cells
    • Costa M, Marchi M, Cardarelli F, Roy A, Beltram F, et al. (2006) Dynamic regulation of ERK2 nuclear translocation and mobility in living cells. J Cell Sci 119: 4952-4963.
    • (2006) J Cell Sci , vol.119 , pp. 4952-4963
    • Costa, M.1    Marchi, M.2    Cardarelli, F.3    Roy, A.4    Beltram, F.5
  • 25
    • 33646852421 scopus 로고    scopus 로고
    • Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes
    • Fujioka A, Terai K, Itoh RE, Aoki K, Nakamura T, et al. (2006) Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes. J Biol Chem 281: 8917-8926.
    • (2006) J Biol Chem , vol.281 , pp. 8917-8926
    • Fujioka, A.1    Terai, K.2    Itoh, R.E.3    Aoki, K.4    Nakamura, T.5
  • 26
    • 0028157664 scopus 로고
    • Atomic structure of the MAP kinase ERK2 at 2.3 A resolution
    • Zhang F, Strand A, Robbins D, Cobb MH, Goldsmith EJ (1994) Atomic structure of the MAP kinase ERK2 at 2.3 A resolution. Nature 367: 704-711.
    • (1994) Nature , vol.367 , pp. 704-711
    • Zhang, F.1    Strand, A.2    Robbins, D.3    Cobb, M.H.4    Goldsmith, E.J.5
  • 27
    • 0028107740 scopus 로고
    • Cytoplasmic localization of the mitogen-activated protein kinase activator MEK
    • Zheng CF, Guan KL (1994) Cytoplasmic localization of the mitogen-activated protein kinase activator MEK. J Biol Chem 269: 19947-19952.
    • (1994) J Biol Chem , vol.269 , pp. 19947-19952
    • Zheng, C.F.1    Guan, K.L.2
  • 28
    • 0034757776 scopus 로고    scopus 로고
    • The nucleus, a site for signal termination by sequestration and inactivation of p42/ p44 MAP kinases
    • Volmat V, Camps M, Arkinstall S, Pouyssegur J, Lenormand P (2001) The nucleus, a site for signal termination by sequestration and inactivation of p42/ p44 MAP kinases. J Cell Sci 114: 3433-3443.
    • (2001) J Cell Sci , vol.114 , pp. 3433-3443
    • Volmat, V.1    Camps, M.2    Arkinstall, S.3    Pouyssegur, J.4    Lenormand, P.5
  • 29
    • 0034610996 scopus 로고    scopus 로고
    • Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism
    • Adachi M, Fukuda M, Nishida E (2000) Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J Cell Biol 148: 849-856.
    • (2000) J Cell Biol , vol.148 , pp. 849-856
    • Adachi, M.1    Fukuda, M.2    Nishida, E.3
  • 30
    • 0031453047 scopus 로고    scopus 로고
    • A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase
    • Fukuda M, Gotoh I, Adachi M, Gotoh Y, Nishida E (1997) A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J Biol Chem 272: 32642-32648.
    • (1997) J Biol Chem , vol.272 , pp. 32642-32648
    • Fukuda, M.1    Gotoh, I.2    Adachi, M.3    Gotoh, Y.4    Nishida, E.5
  • 31
    • 17344362384 scopus 로고    scopus 로고
    • Prediction and validation of the distinct dynamics of transient and sustained ERK activation
    • Sasagawa S, Ozaki Y, Fujita K, Kuroda S (2005) Prediction and validation of the distinct dynamics of transient and sustained ERK activation. Nat Cell Biol 7: 365-373.
    • (2005) Nat Cell Biol , vol.7 , pp. 365-373
    • Sasagawa, S.1    Ozaki, Y.2    Fujita, K.3    Kuroda, S.4
  • 33
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/ p38, and may mediate activation of CREB
    • Deak M, Clifton AD, Lucocq LM, Alessi DR (1998) Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/ p38, and may mediate activation of CREB. Embo J 17: 4426-4441.
    • (1998) Embo J , vol.17 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, L.M.3    Alessi, D.R.4
  • 34
    • 0029893708 scopus 로고    scopus 로고
    • Identification of MAP kinase domains by redirecting stress signals into growth factor responses
    • Brunet A, Pouyssegur J (1996) Identification of MAP kinase domains by redirecting stress signals into growth factor responses. Science 272: 1652-1655.
    • (1996) Science , vol.272 , pp. 1652-1655
    • Brunet, A.1    Pouyssegur, J.2
  • 35
    • 0037177819 scopus 로고    scopus 로고
    • Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1
    • Robinson FL, Whitehurst AW, Raman M, Cobb MH (2002) Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1. J Biol Chem 277: 14844-14852.
    • (2002) J Biol Chem , vol.277 , pp. 14844-14852
    • Robinson, F.L.1    Whitehurst, A.W.2    Raman, M.3    Cobb, M.H.4
  • 36
    • 0033788484 scopus 로고    scopus 로고
    • A conserved docking motif in MAP kinases common to substrates, activators and regulators
    • Tanoue T, Adachi M, Moriguchi T, Nishida E (2000) A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nat Cell Biol 2: 110-116.
    • (2000) Nat Cell Biol , vol.2 , pp. 110-116
    • Tanoue, T.1    Adachi, M.2    Moriguchi, T.3    Nishida, E.4
  • 37
    • 0035834689 scopus 로고    scopus 로고
    • Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells
    • Matsubayashi Y, Fukuda M, Nishida E (2001) Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells. J Biol Chem 276: 41755-41760.
    • (2001) J Biol Chem , vol.276 , pp. 41755-41760
    • Matsubayashi, Y.1    Fukuda, M.2    Nishida, E.3
  • 39
    • 1542284152 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of signal transducers
    • Xu L, Massague J (2004) Nucleocytoplasmic shuttling of signal transducers. Nat Rev Mol Cell Biol 5: 209-219.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 209-219
    • Xu, L.1    Massague, J.2
  • 40
    • 14044251529 scopus 로고    scopus 로고
    • Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5
    • Mandl M, Slack DN, Keyse SM (2005) Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5. Mol Cell Biol 25: 1830-1845.
    • (2005) Mol Cell Biol , vol.25 , pp. 1830-1845
    • Mandl, M.1    Slack, D.N.2    Keyse, S.M.3
  • 41
    • 45549090152 scopus 로고    scopus 로고
    • Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases
    • Chuderland D, Marmor G, Shainskaya A, Seger R (2008) Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. J Biol Chem 283: 11176-11188.
    • (2008) J Biol Chem , vol.283 , pp. 11176-11188
    • Chuderland, D.1    Marmor, G.2    Shainskaya, A.3    Seger, R.4
  • 42
    • 22744448198 scopus 로고    scopus 로고
    • Control of MAP kinase signaling to the nucleus
    • Kondoh K, Torii S, Nishida E (2005) Control of MAP kinase signaling to the nucleus. Chromosoma 114: 86-91.
    • (2005) Chromosoma , vol.114 , pp. 86-91
    • Kondoh, K.1    Torii, S.2    Nishida, E.3
  • 43
    • 34547908162 scopus 로고    scopus 로고
    • Reversibility in nucleocytoplasmic transport
    • Kopito RB, Elbaum M (2007) Reversibility in nucleocytoplasmic transport. Proc Natl Acad Sci U S A 104: 12743-12748.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12743-12748
    • Kopito, R.B.1    Elbaum, M.2
  • 44
    • 33744941875 scopus 로고    scopus 로고
    • The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy
    • Ranganathan A, Yazicioglu MN, Cobb MH (2006) The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy. J Biol Chem 281: 15645-15652.
    • (2006) J Biol Chem , vol.281 , pp. 15645-15652
    • Ranganathan, A.1    Yazicioglu, M.N.2    Cobb, M.H.3
  • 45
    • 52049108218 scopus 로고    scopus 로고
    • Identification and characterization of a general nuclear translocation signal in signaling proteins
    • Chuderland D, Konson A, Seger R (2008) Identification and characterization of a general nuclear translocation signal in signaling proteins. Mol Cell 31: 850-861.
    • (2008) Mol Cell , vol.31 , pp. 850-861
    • Chuderland, D.1    Konson, A.2    Seger, R.3
  • 47
    • 0043127470 scopus 로고    scopus 로고
    • Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK
    • Cancedda L, Putignano E, Impey S, Maffei L, Ratto GM, et al. (2003) Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK. J Neurosci 23: 7012-7020.
    • (2003) J Neurosci , vol.23 , pp. 7012-7020
    • Cancedda, L.1    Putignano, E.2    Impey, S.3    Maffei, L.4    Ratto, G.M.5
  • 48
    • 0034656085 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor causes cAMP response element-binding protein phosphorylation in absence of calcium increases in slices and cultured neurons from rat visual cortex
    • Pizzorusso T, Ratto GM, Putignano E, Maffei L (2000) Brain-derived neurotrophic factor causes cAMP response element-binding protein phosphorylation in absence of calcium increases in slices and cultured neurons from rat visual cortex. J Neurosci 20: 2809-2816.
    • (2000) J Neurosci , vol.20 , pp. 2809-2816
    • Pizzorusso, T.1    Ratto, G.M.2    Putignano, E.3    Maffei, L.4
  • 50
    • 35148894535 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory
    • Satoh Y, Endo S, Ikeda T, Yamada K, Ito M, et al. (2007) Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory. J Neurosci 27: 10765-10776.
    • (2007) J Neurosci , vol.27 , pp. 10765-10776
    • Satoh, Y.1    Endo, S.2    Ikeda, T.3    Yamada, K.4    Ito, M.5
  • 51
    • 0031465906 scopus 로고    scopus 로고
    • Proliferation of human malignant astrocytomas is dependent on Ras activation
    • Guha A, Feldkamp MM, Lau N, Boss G, Pawson A (1997) Proliferation of human malignant astrocytomas is dependent on Ras activation. Oncogene 15: 2755-2765.
    • (1997) Oncogene , vol.15 , pp. 2755-2765
    • Guha, A.1    Feldkamp, M.M.2    Lau, N.3    Boss, G.4    Pawson, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.