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Volumn 25, Issue 5, 2005, Pages 1830-1845

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHOPROTEIN PHOSPHATASE; TRANSCRIPTION FACTOR ELK 1;

EID: 14044251529     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.5.1830-1845.2005     Document Type: Article
Times cited : (170)

References (50)
  • 1
    • 0033215340 scopus 로고    scopus 로고
    • Two co-existing mechanisms for nuclear import of MAP kinase: Passive diffusion of a monomer and active transport of a dimer
    • Adachi, M., M. Fukuda, and E. Nishida. 1999. Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J. 18:5347-5358.
    • (1999) EMBO J. , vol.18 , pp. 5347-5358
    • Adachi, M.1    Fukuda, M.2    Nishida, E.3
  • 2
    • 0037444809 scopus 로고    scopus 로고
    • Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity
    • Bardwell, A. J., M. Abdollahi, and L. Bardwell. 2003. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity. Biochem. J. 370:1077-1085.
    • (2003) Biochem. J. , vol.370 , pp. 1077-1085
    • Bardwell, A.J.1    Abdollahi, M.2    Bardwell, L.3
  • 3
    • 0033081066 scopus 로고    scopus 로고
    • Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
    • Brunet, A., D. Roux, P. Lenormand, S. Dowd, S. Keyse, and J. Pouyssegur. 1999. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J. 18:664-674.
    • (1999) EMBO J. , vol.18 , pp. 664-674
    • Brunet, A.1    Roux, D.2    Lenormand, P.3    Dowd, S.4    Keyse, S.5    Pouyssegur, J.6
  • 4
    • 0028328631 scopus 로고
    • A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways
    • Brunner, D., N. Oellers, J. Szabad, W. H. Biggs III, S. L. Zipursky, and E. Hafen. 1994. A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell 76:875-888.
    • (1994) Cell , vol.76 , pp. 875-888
    • Brunner, D.1    Oellers, N.2    Szabad, J.3    Biggs III, W.H.4    Zipursky, S.L.5    Hafen, E.6
  • 5
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: A gene family for control of MAP kinase function
    • Camps, M., A. Nichols, and S. Arkinstall. 2000. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J. 14:6-16.
    • (2000) FASEB J. , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 7
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 8
    • 0035800855 scopus 로고    scopus 로고
    • Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically
    • Chen, P., D. Hutter, X. Yang, M. Gorospe, R. J. Davis, and Y. Liu. 2001. Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically. J. Biol. Chem. 276:29440-29449.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29440-29449
    • Chen, P.1    Hutter, D.2    Yang, X.3    Gorospe, M.4    Davis, R.J.5    Liu, Y.6
  • 9
    • 0026608787 scopus 로고
    • Nuclear localization and regulation of erk- and rsk-encoded protein kinases
    • Chen, R. H., C. Sarnecki, and J. Blenis. 1992. Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol. Cell. Biol. 12:915-927.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 915-927
    • Chen, R.H.1    Sarnecki, C.2    Blenis, J.3
  • 10
    • 0029918680 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation
    • Chu, Y., P. A. Solski, R. Khosravi-Far, C. J. Der, and K. Kelly. 1996. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J. Biol. Chem. 271:6497-6501.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6497-6501
    • Chu, Y.1    Solski, P.A.2    Khosravi-Far, R.3    Der, C.J.4    Kelly, K.5
  • 11
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis, R. J. 1993. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:14553-14556.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 12
    • 0037093408 scopus 로고    scopus 로고
    • Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase
    • Dickinson, R. J., D. J. Williams, D. N. Slack, J. Williamson, O. M. Seternes, and S. M. Keyse. 2002. Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase. Biochem. J. 364:145-155.
    • (2002) Biochem. J. , vol.364 , pp. 145-155
    • Dickinson, R.J.1    Williams, D.J.2    Slack, D.N.3    Williamson, J.4    Seternes, O.M.5    Keyse, S.M.6
  • 13
    • 0029757347 scopus 로고    scopus 로고
    • Disruption of the erp/mkp-1 gene does not affect mouse development: Normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts
    • Dorfman, K., D. Carrasco, M. Gruda, C. Ryan, S. A. Lira, and R. Bravo. 1996. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. Oncogene 13:925-931.
    • (1996) Oncogene , vol.13 , pp. 925-931
    • Dorfman, K.1    Carrasco, D.2    Gruda, M.3    Ryan, C.4    Lira, S.A.5    Bravo, R.6
  • 14
    • 0031775763 scopus 로고    scopus 로고
    • Isolation of the human genes encoding the Pyst1 and Pyst2 phosphatases: Characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases
    • Dowd, S., A. A. Sneddon, and S. M. Keyse. 1998. Isolation of the human genes encoding the Pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases. J. Cell Sci. 111:3389-3399.
    • (1998) J. Cell Sci. , vol.111 , pp. 3389-3399
    • Dowd, S.1    Sneddon, A.A.2    Keyse, S.M.3
  • 17
    • 0029786994 scopus 로고    scopus 로고
    • Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal
    • Fukuda, M., I. Gotoh, Y. Gotoh, and E. Nishida. 1996. Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J. Biol. Chem. 271:20024-20028.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20024-20028
    • Fukuda, M.1    Gotoh, I.2    Gotoh, Y.3    Nishida, E.4
  • 18
    • 0030972494 scopus 로고    scopus 로고
    • Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase
    • Fukuda, M., Y. Gotoh, and E. Nishida. 1997. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 16:1901-1908.
    • (1997) EMBO J. , vol.16 , pp. 1901-1908
    • Fukuda, M.1    Gotoh, Y.2    Nishida, E.3
  • 19
    • 0027225936 scopus 로고
    • Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus
    • Gonzalez, F. A., A. Seth, D. L. Raden, D. S. Bowman, F. S. Fay, and R. J. Davis. 1993. Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus. J. Cell Biol. 122:1089-1101.
    • (1993) J. Cell Biol. , vol.122 , pp. 1089-1101
    • Gonzalez, F.A.1    Seth, A.2    Raden, D.L.3    Bowman, D.S.4    Fay, F.S.5    Davis, R.J.6
  • 20
    • 0029905354 scopus 로고    scopus 로고
    • Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
    • Groom, L. A., A. A. Sneddon, D. R. Alessi, S. Dowd, and S. M. Keyse. 1996. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J. 15:3621-3632.
    • (1996) EMBO J. , vol.15 , pp. 3621-3632
    • Groom, L.A.1    Sneddon, A.A.2    Alessi, D.R.3    Dowd, S.4    Keyse, S.M.5
  • 21
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 22
    • 0028019743 scopus 로고
    • A novel dual specificity phosphatase induced by serum stimulation and heat shock
    • Ishibashi, T., D. P. Bottaro, P. Michieli, C. A. Kelley, and S. A. Aaronson. 1994. A novel dual specificity phosphatase induced by serum stimulation and heat shock. J. Biol. Chem. 269:29897-29902.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29897-29902
    • Ishibashi, T.1    Bottaro, D.P.2    Michieli, P.3    Kelley, C.A.4    Aaronson, S.A.5
  • 23
    • 0030935258 scopus 로고    scopus 로고
    • Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation
    • Jaaro, H., H. Rubinfeld, T. Hanoch, and R. Seger. 1997. Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation. Proc. Natl. Acad. Sci. USA 94:3742-3747.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3742-3747
    • Jaaro, H.1    Rubinfeld, H.2    Hanoch, T.3    Seger, R.4
  • 24
    • 4744365623 scopus 로고    scopus 로고
    • Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal
    • Karlsson, M., J. Mathers, R. J. Dickinson, M. Mandl, and S. M. Keyse. 2004. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal. J. Biol. Chem. 279:41882-41891.
    • (2004) J. Biol. Chem. , vol.279 , pp. 41882-41891
    • Karlsson, M.1    Mathers, J.2    Dickinson, R.J.3    Mandl, M.4    Keyse, S.M.5
  • 25
    • 0034096201 scopus 로고    scopus 로고
    • Protein phosphatases and the regulation of mitogen-activated protein kinase signalling
    • Keyse, S. M. 2000. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr. Opin. Cell Biol. 12:186-192.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 186-192
    • Keyse, S.M.1
  • 27
    • 0038813748 scopus 로고    scopus 로고
    • Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling
    • Kovanen, P. E., A. Rosenwald, J. Fu, E. M. Hurt, L. T. Lam, J. M. Giltnane, G. Wright, L. M. Staudt, and W. J. Leonard. 2003. Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling. J. Biol. Chem. 278:5205-5213.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5205-5213
    • Kovanen, P.E.1    Rosenwald, A.2    Fu, J.3    Hurt, E.M.4    Lam, L.T.5    Giltnane, J.M.6    Wright, G.7    Staudt, L.M.8    Leonard, W.J.9
  • 28
    • 0028816845 scopus 로고
    • Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines
    • Kwak, S. P., and J. E. Dixon. 1995. Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines. J. Biol. Chem. 270:1156-1160.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1156-1160
    • Kwak, S.P.1    Dixon, J.E.2
  • 29
    • 0030005755 scopus 로고    scopus 로고
    • The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression
    • Lennon, G., C. Auffray, M. Polymeropoulos, and M. B. Soares. 1996. The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152.
    • (1996) Genomics , vol.33 , pp. 151-152
    • Lennon, G.1    Auffray, C.2    Polymeropoulos, M.3    Soares, M.B.4
  • 30
    • 0031852068 scopus 로고    scopus 로고
    • Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins
    • Lenormand, P., J. M. Brondello, A. Brunet, and J. Pouyssegur. 1998. Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins. J. Cell Biol. 142:625-633.
    • (1998) J. Cell Biol. , vol.142 , pp. 625-633
    • Lenormand, P.1    Brondello, J.M.2    Brunet, A.3    Pouyssegur, J.4
  • 31
    • 0027283659 scopus 로고
    • Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
    • Lenormand, P., C. Sardet, G. Pages, G. L'Allemain, A. Brunet, and J. Pouyssegur. 1993. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J. Cell Biol. 122:1079-1088.
    • (1993) J. Cell Biol. , vol.122 , pp. 1079-1088
    • Lenormand, P.1    Sardet, C.2    Pages, G.3    L'Allemain, G.4    Brunet, A.5    Pouyssegur, J.6
  • 32
    • 0029910140 scopus 로고    scopus 로고
    • The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases
    • Muda, M., A. Theodosiou, N. Rodrigues, U. Boscbert, M. Camps, C. Gillieron, K. Davies, A. Ashworth, and S. Arkinstall. 1996. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases. J. Biol. Chem. 271:27205-27208.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27205-27208
    • Muda, M.1    Theodosiou, A.2    Rodrigues, N.3    Boscbert, U.4    Camps, M.5    Gillieron, C.6    Davies, K.7    Ashworth, A.8    Arkinstall, S.9
  • 33
    • 0034637573 scopus 로고    scopus 로고
    • Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3
    • Nichols, A., M. Camps, C. Gillieron, C. Chabert, A. Brunet, J. Wilsbacber, M. Cobb, J. Pouyssegur, J. P. Shaw, and S. Arkinstall. 2000. Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3. J. Biol. Chem. 275:24613-24621.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24613-24621
    • Nichols, A.1    Camps, M.2    Gillieron, C.3    Chabert, C.4    Brunet, A.5    Wilsbacber, J.6    Cobb, M.7    Pouyssegur, J.8    Shaw, J.P.9    Arkinstall, S.10
  • 34
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathways
    • Nishida, E., and Y. Gotoh. 1993. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18:128-131.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 35
    • 0041926731 scopus 로고    scopus 로고
    • Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
    • Pouyssegur, J., and P. Lenormand. 2003. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Eur. J. Biochem. 270:3291-3299.
    • (2003) Eur. J. Biochem. , vol.270 , pp. 3291-3299
    • Pouyssegur, J.1    Lenormand, P.2
  • 36
    • 0036709020 scopus 로고    scopus 로고
    • Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
    • Pouyssegur, J., V. Volmat, and P. Lenormand. 2002. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem. Pharmacol. 64:755-763.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 755-763
    • Pouyssegur, J.1    Volmat, V.2    Lenormand, P.3
  • 37
    • 0035836486 scopus 로고    scopus 로고
    • Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase
    • Rigas, J. D., R. H. Hoff, A. E. Rice, A. C. Hengge, and J. M. Denu. 2001. Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase. Biochemistry 40:4398-4406.
    • (2001) Biochemistry , vol.40 , pp. 4398-4406
    • Rigas, J.D.1    Hoff, R.H.2    Rice, A.E.3    Hengge, A.C.4    Denu, J.M.5
  • 38
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson, M. J., and M. H. Cobb. 1997. Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 9:180-186.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 39
    • 0035844140 scopus 로고    scopus 로고
    • Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1
    • Slack, D. N., O. M. Seternes, M. Gabrielsen, and S. M. Keyse. 2001. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1. J. Biol. Chem. 276:16491-16500.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16491-16500
    • Slack, D.N.1    Seternes, O.M.2    Gabrielsen, M.3    Keyse, S.M.4
  • 40
    • 0032910476 scopus 로고    scopus 로고
    • Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation
    • Stewart, A. E., S. Dowd, S. M. Keyse, and N. Q. McDonald. 1999. Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation. Nat. Struct. Biol. 6:174-181.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 174-181
    • Stewart, A.E.1    Dowd, S.2    Keyse, S.M.3    McDonald, N.Q.4
  • 41
    • 0033788484 scopus 로고    scopus 로고
    • A conserved docking motif in MAP kinases common to substrates, activators and regulators
    • Tanoue, T., M. Adachi, T. Moriguchi, and E. Nishida. 2000. A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nat. Cell Biol. 2:110-116.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 110-116
    • Tanoue, T.1    Adachi, M.2    Moriguchi, T.3    Nishida, E.4
  • 42
    • 0033538489 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5
    • Tanoue, T., T. Moriguchi, and E. Nishida. 1999. Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5. J. Biol. Chem. 274:19949-19956.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19949-19956
    • Tanoue, T.1    Moriguchi, T.2    Nishida, E.3
  • 43
    • 0036380174 scopus 로고    scopus 로고
    • MAP kinase phosphatases
    • 26 June posting date. reviews1-3009.10. [Online]
    • Theodosiou, A., and A. Ashworth. 26 June 2002 posting date. MAP kinase phosphatases. Genome Biol. 3:reviews1-3009.10. [Online.] http: //genomebiology.com/2002/3/7/reviews/3009.
    • (2002) Genome Biol. , vol.3
    • Theodosiou, A.1    Ashworth, A.2
  • 44
    • 0033525528 scopus 로고    scopus 로고
    • Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK
    • Tolwinski, N. S., P. S. Shapiro, S. Goueli, and N. G. Ahn. 1999. Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK. J. Biol. Chem. 274:6168-6174.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6168-6174
    • Tolwinski, N.S.1    Shapiro, P.S.2    Goueli, S.3    Ahn, N.G.4
  • 46
    • 0041836252 scopus 로고    scopus 로고
    • Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53
    • Ueda, K., H. Arakawa, and Y. Nakamura. 2003. Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53. Oncogene 22:5586-5591.
    • (2003) Oncogene , vol.22 , pp. 5586-5591
    • Ueda, K.1    Arakawa, H.2    Nakamura, Y.3
  • 47
    • 0034757776 scopus 로고    scopus 로고
    • The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases
    • Volmat, V., M. Camps, S. Arkinstall, J. Pouyssegur, and P. Lenormand. 2001. The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases. J. Cell Sci. 114:3433-3443.
    • (2001) J. Cell Sci. , vol.114 , pp. 3433-3443
    • Volmat, V.1    Camps, M.2    Arkinstall, S.3    Pouyssegur, J.4    Lenormand, P.5
  • 48
    • 0032103332 scopus 로고    scopus 로고
    • Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway
    • Wasylyk, B., J. Hagman, and A. Gutierrez-Hartmann. 1998. Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biochem. Sci. 23:213-216.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 213-216
    • Wasylyk, B.1    Hagman, J.2    Gutierrez-Hartmann, A.3
  • 49
    • 0242361581 scopus 로고    scopus 로고
    • Transcriptional regulation by the MAP kinase signaling cascades
    • Yang, S. H., A. D. Sharrocks, and A. J. Whitmarsh. 2003. Transcriptional regulation by the MAP kinase signaling cascades. Gene 320:3-21.
    • (2003) Gene , vol.320 , pp. 3-21
    • Yang, S.H.1    Sharrocks, A.D.2    Whitmarsh, A.J.3
  • 50
    • 0033544855 scopus 로고    scopus 로고
    • Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2
    • Zhou, B., and Z. Y. Zhang. 1999. Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2. J. Biol. Chem. 274:35526-35534.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35526-35534
    • Zhou, B.1    Zhang, Z.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.