-
1
-
-
0031158805
-
The physiological function of drug-transporting P-glycoproteins
-
AH Schinkel 1997 The physiological function of drug-transporting P-glycoproteins Semin Cancer Biol 8 161 170
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
2
-
-
0024791333
-
Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay
-
K Ueda Y Yamano N Kioka 1989 Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay Jpn J Cancer Res 80 1127 1132
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 1127-1132
-
-
Ueda, K.1
Yamano, Y.2
Kioka, N.3
-
3
-
-
0030589989
-
Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells
-
KM Barnes B Dickstein GB Cutler 1996 Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells Biochemistry 35 4820 4827
-
(1996)
Biochemistry
, vol.35
, pp. 4820-4827
-
-
Barnes, K.M.1
Dickstein, B.2
Cutler, G.B.3
-
4
-
-
0035049879
-
The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene
-
TR Pippert DR Umbenhauer 2001 The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene J Biochem Mol Toxicol 15 83 89
-
(2001)
J Biochem Mol Toxicol
, vol.15
, pp. 83-89
-
-
Pippert, T.R.1
Umbenhauer, D.R.2
-
5
-
-
0345411341
-
P-glycoprotein and cytochrome P-450 3A inhibition: Dissociation of inhibitory potencies
-
C Wandel RB Kim S Kajiji 1999 P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies Cancer Res 59 3944 3948
-
(1999)
Cancer Res
, vol.59
, pp. 3944-3948
-
-
Wandel, C.1
Kim, R.B.2
Kajiji, S.3
-
6
-
-
0029916534
-
P-glycoprotein: A major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans
-
EG Schuetz AH Schinkel MV Relling 1996 P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans Proc Natl Acad Sci USA 93 4001 4005
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4001-4005
-
-
Schuetz, E.G.1
Schinkel, A.H.2
Relling, M.V.3
-
7
-
-
0033616684
-
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
-
VV Rao JL Dahlheimer ME Bardgett 1999 Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier Proc Natl Acad Sci USA 96 3900 3905
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3900-3905
-
-
Rao, V.V.1
Dahlheimer, J.L.2
Bardgett, M.E.3
-
8
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
S Hoffmeyer O Burk O von Richter 2000 Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo Proc Natl Acad Sci USA 97 3473 3478
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
-
9
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the penetration on pharmacological activity of many drugs
-
AH Schinkel E Wagenaar CAAM Mol 1996 P-glycoprotein in the blood-brain barrier of mice influences the penetration on pharmacological activity of many drugs J Clin İnvest 97 2517 2524
-
(1996)
J Clin İnvest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Caam, M.3
-
10
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
F Thiebaut T Tsuruo H Hamada 1987 Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc Natl Acad Sci USA 84 7735 7738
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
-
11
-
-
0032562111
-
Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells
-
H Huai-Yun DT Secrest KS Mark 1998 Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells Biochem Biophys Res Commun 243 816 820
-
(1998)
Biochem Biophys Res Commun
, vol.243
, pp. 816-820
-
-
Huai-Yun, H.1
Secrest, D.T.2
Mark, K.S.3
-
12
-
-
0024362996
-
P-glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly 185 with an altered pattern of multidrug resistance
-
N Kioka J Tsubota Y Kakehi 1989 P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly 185 with an altered pattern of multidrug resistance Biochem Biophys Res Commun 162 224 231
-
(1989)
Biochem Biophys Res Commun
, vol.162
, pp. 224-231
-
-
Kioka, N.1
Tsubota, J.2
Kakehi, Y.3
-
13
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in teh P-glycoprotein drug transporter MDR-1 gene in white subjects
-
I Cascorbi T Gerloff A Johne 2001 Frequency of single nucleotide polymorphisms in teh P-glycoprotein drug transporter MDR-1 gene in white subjects Clin Pharmacol Ther 69 169 174
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
-
14
-
-
0030975889
-
Genetic dissection of the function of mammalian P-glycoproteins
-
P Borst AH Schinkel 1997 Genetic dissection of the function of mammalian P-glycoproteins Trends Genet 13 217 222
-
(1997)
Trends Genet
, vol.13
, pp. 217-222
-
-
Borst, P.1
Schinkel, A.H.2
-
17
-
-
0037330517
-
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
-
B Chowbay S Cumaraswamy YB Cheung 2003 Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients Pharmacogenetics 13 89 95
-
(2003)
Pharmacogenetics
, vol.13
, pp. 89-95
-
-
Chowbay, B.1
Cumaraswamy, S.2
Cheung, Y.B.3
-
18
-
-
0035752933
-
The predictive value of MDR1, CYP2C9, and CUP2C19 polymorphisms for phenytoin plasma levels
-
R Kerb AS Aynacioglu J Brockmoller 2001 The predictive value of MDR1, CYP2C9, and CUP2C19 polymorphisms for phenytoin plasma levels Pharmacogenomics J 1 204 210
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 204-210
-
-
Kerb, R.1
Aynacioglu, A.S.2
Brockmoller, J.3
-
19
-
-
0041627670
-
Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer
-
A Kafka G Sauer C Jaeger 2003 Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer Int J Oncol 22 1117 1121
-
(2003)
Int J Oncol
, vol.22
, pp. 1117-1121
-
-
Kafka, A.1
Sauer, G.2
Jaeger, C.3
-
20
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
-
J Fellay C Marzolini E Meaden 2002 Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study Lancet 359 30 36
-
(2002)
Lancet
, vol.359
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.3
-
21
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
A Siddiqui R Kerb ME Weale 2003 Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1 N Engl J Med 348 1442 1448
-
(2003)
N Engl J Med
, vol.348
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
-
22
-
-
0036729669
-
The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients
-
H Zheng S Webber A Zeevi 2002 The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients Hum Immunol 63 765 770
-
(2002)
Hum Immunol
, vol.63
, pp. 765-770
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
-
23
-
-
0036739659
-
Effect of levothyroxine administration on intestinal P-glycoprotein expression: Consequences for drug disposition
-
W Siegmund S Altmannsberger A Paneitz 2002 Effect of levothyroxine administration on intestinal P-glycoprotein expression: consequences for drug disposition Clin Pharmacol Ther 72 256 264
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 256-264
-
-
Siegmund, W.1
Altmannsberger, S.2
Paneitz, A.3
-
24
-
-
3242728359
-
Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor
-
T Mitin LL Von Moltke MH Court 2004 Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor Drug Metab Dispos 32 779 782
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 779-782
-
-
Mitin, T.1
Von Moltke, L.L.2
Court, M.H.3
-
25
-
-
33644824363
-
Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease
-
MJ Simmonds JM Heward J Carr-Smith 2006 Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease J Clin Endocrinol Metab 91 1056 1061
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1056-1061
-
-
Simmonds, M.J.1
Heward, J.M.2
Carr-Smith, J.3
-
26
-
-
0024362996
-
P-glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly 185 with an altered pattern of multidrug resistance
-
N Kioka J Tsubota Y Kakehi 1989 P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly 185 with an altered pattern of multidrug resistance Biochem Biophys Res Commun 162 224 231
-
(1989)
Biochem Biophys Res Commun
, vol.162
, pp. 224-231
-
-
Kioka, N.1
Tsubota, J.2
Kakehi, Y.3
-
27
-
-
33751064143
-
Genotype and allele frequency of human multidrug resistance (MDR1) gene C3435T polymorphism in Denizli province of Turkey
-
S Turgut G Turgut EÖ Atalay 2006 Genotype and allele frequency of human multidrug resistance (MDR1) gene C3435T polymorphism in Denizli province of Turkey Mol Biol Rep 33 295 300
-
(2006)
Mol Biol Rep
, vol.33
, pp. 295-300
-
-
Turgut, S.1
Turgut, G.2
Atalay, E.Ö.3
-
28
-
-
34249886041
-
The MDR1 C3435T polymorphism in patients with breast cancer
-
S Turgut A Yaren R Kurşunluoǧlu 2007 The MDR1 C3435T polymorphism in patients with breast cancer Arch Med Res 38 539 544
-
(2007)
Arch Med Res
, vol.38
, pp. 539-544
-
-
Turgut, S.1
Yaren, A.2
Kurşunluoǧlu, R.3
-
29
-
-
0036155881
-
Thyroid hormone export varies among primary cells and appears to differ from hormone uptake
-
FA Neves RR Cavalieri LA Simeoni 2002 Thyroid hormone export varies among primary cells and appears to differ from hormone uptake Endocrinology 143 476 483
-
(2002)
Endocrinology
, vol.143
, pp. 476-483
-
-
Neves, F.A.1
Cavalieri, R.R.2
Simeoni, L.A.3
-
30
-
-
17844369473
-
Thyroid hormone export from cells: Contribution of P-glycoprotein
-
AM Mitchell M Tom RH Mortimer 2005 Thyroid hormone export from cells: contribution of P-glycoprotein J Endocrinol 185 93 98
-
(2005)
J Endocrinol
, vol.185
, pp. 93-98
-
-
Mitchell, A.M.1
Tom, M.2
Mortimer, R.H.3
-
31
-
-
0029884539
-
Membrane iodothyronine transporters, Part II: Review of protein biochemistry
-
L Kragie 1996 Membrane iodothyronine transporters, Part II: review of protein biochemistry Endocr Res 22 95 119
-
(1996)
Endocr Res
, vol.22
, pp. 95-119
-
-
Kragie, L.1
-
33
-
-
0023543266
-
Clinical pharmacokinetics and endocrine disorders-therapeutic implications
-
P O'Connor J Feely 1987 Clinical pharmacokinetics and endocrine disorders-therapeutic implications Clin Pharmacokinet 13 345 364
-
(1987)
Clin Pharmacokinet
, vol.13
, pp. 345-364
-
-
O'Connor, P.1
Feely, J.2
-
34
-
-
0019840724
-
Influence of thyroid dysfunction on drug pharmacokinetics
-
GM Shenfield 1981 Influence of thyroid dysfunction on drug pharmacokinetics Clin Pharmacokinet 6 275 297
-
(1981)
Clin Pharmacokinet
, vol.6
, pp. 275-297
-
-
Shenfield, G.M.1
-
35
-
-
0030055356
-
Thyroid hormone export regulates cellular hormone content and response
-
RC Ribeiro RR Cavalieri N Lomri 1996 Thyroid hormone export regulates cellular hormone content and response J Biol Chem 271 17147 17151
-
(1996)
J Biol Chem
, vol.271
, pp. 17147-17151
-
-
Ribeiro, R.C.1
Cavalieri, R.R.2
Lomri, N.3
-
36
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
RB Kim BF Leake EF Choo 2001 Identification of functionally variant MDR1 alleles among European Americans and African Americans Clin Pharmacol Ther 70 189 199
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
|