메뉴 건너뛰기




Volumn 7, Issue 12, 2008, Pages 2037-2051

Nonapoptotic death of Saccharomyces cerevisiae cells that is stimulated by Hsp90 and inhibited by calcineurin and Cmk2 in response to endoplasmic reticulum stresses

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CMK2 PROTEIN, S CEREVISIAE; HEAT SHOCK PROTEIN 90; HSP82 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; TUNICAMYCIN;

EID: 57349114323     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00291-08     Document Type: Article
Times cited : (43)

References (72)
  • 1
    • 11844276610 scopus 로고    scopus 로고
    • Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae
    • Ahn, S. H., W. L. Cheung, J. Y. Hsu, R. L. Diaz, M. M. Smith, and C. D. Allis. 2005. Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell 120:25-36.
    • (2005) Cell , vol.120 , pp. 25-36
    • Ahn, S.H.1    Cheung, W.L.2    Hsu, J.Y.3    Diaz, R.L.4    Smith, M.M.5    Allis, C.D.6
  • 2
    • 0027435667 scopus 로고
    • Effect of miconazole on the structure and function of plasma membrane of Candida albicans
    • Ansari, S., and R. Prasad. 1993. Effect of miconazole on the structure and function of plasma membrane of Candida albicans. FEMS Microbiol. Lett. 114:93-98.
    • (1993) FEMS Microbiol. Lett , vol.114 , pp. 93-98
    • Ansari, S.1    Prasad, R.2
  • 5
    • 0141764710 scopus 로고    scopus 로고
    • MAP kinase stimulation of Ca2+ signaling is required for survival of endoplasmic reticulum stress in yeast
    • Bonilla, M., and K. W. Cunningham. 2003. MAP kinase stimulation of Ca2+ signaling is required for survival of endoplasmic reticulum stress in yeast. Mol. Biol. Cell 14:4296-4305.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 4296-4305
    • Bonilla, M.1    Cunningham, K.W.2
  • 6
    • 0037093384 scopus 로고    scopus 로고
    • Essential role of calcineurin in response to endoplasmic reticulum stress
    • Bonilla, M., K. K. Nastase, and K. W. Cunningham. 2002. Essential role of calcineurin in response to endoplasmic reticulum stress. EMBO J. 21:2343-2353.
    • (2002) EMBO J , vol.21 , pp. 2343-2353
    • Bonilla, M.1    Nastase, K.K.2    Cunningham, K.W.3
  • 7
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
    • Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li, P. Hieter, and J. D. Boeke. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115-132.
    • (1998) Yeast , vol.14 , pp. 115-132
    • Brachmann, C.B.1    Davies, A.2    Cost, G.J.3    Caputo, E.4    Li, J.5    Hieter, P.6    Boeke, J.D.7
  • 8
    • 33747761623 scopus 로고    scopus 로고
    • The role of Yap1p and Skn7p-mediated oxidative stress response in the defence of Saccharomyces cerevisiae against singlet oxygen
    • Brombacher, K., B. Fischer, K. Rüfenacht, and R. Eggen. 2006. The role of Yap1p and Skn7p-mediated oxidative stress response in the defence of Saccharomyces cerevisiae against singlet oxygen. Yeast 23:741-750.
    • (2006) Yeast , vol.23 , pp. 741-750
    • Brombacher, K.1    Fischer, B.2    Rüfenacht, K.3    Eggen, R.4
  • 9
    • 33745049690 scopus 로고    scopus 로고
    • Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease
    • Bultynck, G., V. Heath, A. Majeed, J. Galan, R. Haguenauer-Tsapis, and M. Cyert. 2006. Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol. Cell. Biol. 26:4729-4745.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 4729-4745
    • Bultynck, G.1    Heath, V.2    Majeed, A.3    Galan, J.4    Haguenauer-Tsapis, R.5    Cyert, M.6
  • 12
    • 33748081967 scopus 로고    scopus 로고
    • Nephrotoxicity of cyclosporin A: Short-term gain, long-term pain?
    • Chapman, J., and B. Nankivell. 2006. Nephrotoxicity of cyclosporin A: short-term gain, long-term pain? Nephrol. Dial. Transplant. 21:2060-2063.
    • (2006) Nephrol. Dial. Transplant , vol.21 , pp. 2060-2063
    • Chapman, J.1    Nankivell, B.2
  • 13
    • 29944445793 scopus 로고    scopus 로고
    • Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae
    • Chen, Y., D. E. Feldman, C. Deng, J. A. Brown, A. F. De Giacomo, A. F. Gaw, G. Shi, Q. T. Le, J. M. Brown, and A. C. Koong. 2005. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol. Cancer Res. 3:669-677.
    • (2005) Mol. Cancer Res , vol.3 , pp. 669-677
    • Chen, Y.1    Feldman, D.E.2    Deng, C.3    Brown, J.A.4    De Giacomo, A.F.5    Gaw, A.F.6    Shi, G.7    Le, Q.T.8    Brown, J.M.9    Koong, A.C.10
  • 16
    • 0035675838 scopus 로고    scopus 로고
    • Genetic analysis of calmodulin and its targets in Saccharomyces cerevisiae
    • Cyert, M. S. 2001. Genetic analysis of calmodulin and its targets in Saccharomyces cerevisiae. Annu. Rev. Genet. 35:647-672.
    • (2001) Annu. Rev. Genet , vol.35 , pp. 647-672
    • Cyert, M.S.1
  • 17
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial, N. N., and S. J. Korsmeyer. 2004. Cell death: critical control points. Cell 116:205-219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 18
    • 0033998663 scopus 로고    scopus 로고
    • Synergistic antifungal activities of bafilomycin A1, fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans
    • Del Poeta, M., M. C. Cruz, M. E. Cardenas, J. R. Perfect, and J. Heitman. 2000. Synergistic antifungal activities of bafilomycin A1, fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans. Antimicrob. Agents Chemother. 44:739-746.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 739-746
    • Del Poeta, M.1    Cruz, M.C.2    Cardenas, M.E.3    Perfect, J.R.4    Heitman, J.5
  • 19
    • 34247469791 scopus 로고    scopus 로고
    • The mitochondrial pathway in yeast apoptosis
    • Eisenberg, T., S. Buttner, G. Kroemer, and F. Madeo. 2007. The mitochondrial pathway in yeast apoptosis. Apoptosis 12:1011-1023.
    • (2007) Apoptosis , vol.12 , pp. 1011-1023
    • Eisenberg, T.1    Buttner, S.2    Kroemer, G.3    Madeo, F.4
  • 20
    • 0027262170 scopus 로고
    • Mechanisms of action of systemic antifungal agents
    • Elewski, B. E. 1993. Mechanisms of action of systemic antifungal agents. J. Am. Acad. Dermatol. 28:S28-S34.
    • (1993) J. Am. Acad. Dermatol , vol.28
    • Elewski, B.E.1
  • 21
    • 0347917233 scopus 로고    scopus 로고
    • The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis
    • Fahrenkrog, B., U. Sauder, and U. Aebi. 2004. The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J. Cell Sci. 117:115-126.
    • (2004) J. Cell Sci , vol.117 , pp. 115-126
    • Fahrenkrog, B.1    Sauder, U.2    Aebi, U.3
  • 22
    • 13244264954 scopus 로고    scopus 로고
    • Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase
    • Gin, P., and C. F. Clarke. 2005. Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase. J. Biol. Chem. 280:2676-2681.
    • (2005) J. Biol. Chem , vol.280 , pp. 2676-2681
    • Gin, P.1    Clarke, C.F.2
  • 23
    • 0020739930 scopus 로고
    • Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site
    • Guarente, L., and T. Mason. 1983. Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell 32:1279-1286.
    • (1983) Cell , vol.32 , pp. 1279-1286
    • Guarente, L.1    Mason, T.2
  • 24
    • 14644443504 scopus 로고    scopus 로고
    • Functional characterization of human proapoptotic molecules in yeast S. cerevisiae
    • Guscetti, F., N. Nath, and N. Denko. 2005. Functional characterization of human proapoptotic molecules in yeast S. cerevisiae. FASEB J. 19:464-466.
    • (2005) FASEB J , vol.19 , pp. 464-466
    • Guscetti, F.1    Nath, N.2    Denko, N.3
  • 26
    • 49649098827 scopus 로고    scopus 로고
    • Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging
    • Hauptmann, P., and L. Lehle. 2008. Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging. J. Biol. Chem. 283:19151-19163.
    • (2008) J. Biol. Chem , vol.283 , pp. 19151-19163
    • Hauptmann, P.1    Lehle, L.2
  • 28
    • 4444265582 scopus 로고    scopus 로고
    • Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death
    • Haynes, C. M., E. A. Titus, and A. A. Cooper. 2004. Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death. Mol. Cell 15:767-776.
    • (2004) Mol. Cell , vol.15 , pp. 767-776
    • Haynes, C.M.1    Titus, E.A.2    Cooper, A.A.3
  • 29
    • 2942633721 scopus 로고    scopus 로고
    • Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae
    • Heath, V. L., S. L. Shaw, S. Roy, and M. S. Cyert. 2004. Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot. Cell 3:695-704.
    • (2004) Eukaryot. Cell , vol.3 , pp. 695-704
    • Heath, V.L.1    Shaw, S.L.2    Roy, S.3    Cyert, M.S.4
  • 31
    • 0347758480 scopus 로고    scopus 로고
    • Hilioti, Z., D. A. Gallagher, S. T. Low-Nam, P. Ramaswamy, P. Gajer, T. J. Kingsbury, C. J. Birchwood, A. Levchenko, and K. W. Cunningham. 2004. GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs. Genes Dev. 18:35-47.
    • Hilioti, Z., D. A. Gallagher, S. T. Low-Nam, P. Ramaswamy, P. Gajer, T. J. Kingsbury, C. J. Birchwood, A. Levchenko, and K. W. Cunningham. 2004. GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs. Genes Dev. 18:35-47.
  • 32
    • 0034458959 scopus 로고    scopus 로고
    • Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin
    • Imai, J., and I. Yahara. 2000. Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin. Mol. Cell. Biol. 20:9262-9270.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 9262-9270
    • Imai, J.1    Yahara, I.2
  • 34
    • 0034234963 scopus 로고    scopus 로고
    • A conserved family of calcineurin regulators
    • Kingsbury, T. J., and K. W. Cunningham. 2000. A conserved family of calcineurin regulators. Genes Dev. 13:1595-1604.
    • (2000) Genes Dev , vol.13 , pp. 1595-1604
    • Kingsbury, T.J.1    Cunningham, K.W.2
  • 35
    • 36849020875 scopus 로고    scopus 로고
    • The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurin
    • Kishi, T., A. Ikeda, R. Nagao, and N. Koyama. 2007. The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurin. Proc. Natl. Acad. Sci. USA 104:17418-17423.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 17418-17423
    • Kishi, T.1    Ikeda, A.2    Nagao, R.3    Koyama, N.4
  • 36
    • 33846024762 scopus 로고    scopus 로고
    • Evaluation of the roles of apoptosis, autophagy, and mitophagy in the loss of plating efficiency induced by Bax expression in yeast
    • Kissova, I., L. T. Plamondon, L. Brisson, M. Priault, V. Renouf, J. Schaeffer, N. Camougrand, and S. Manon. 2006. Evaluation of the roles of apoptosis, autophagy, and mitophagy in the loss of plating efficiency induced by Bax expression in yeast. J. Biol. Chem. 281:36187-36197.
    • (2006) J. Biol. Chem , vol.281 , pp. 36187-36197
    • Kissova, I.1    Plamondon, L.T.2    Brisson, L.3    Priault, M.4    Renouf, V.5    Schaeffer, J.6    Camougrand, N.7    Manon, S.8
  • 37
    • 0038460048 scopus 로고    scopus 로고
    • The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function
    • Kraus, P. R., D. S. Fox, G. M. Cox, and J. Heitman. 2003. The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Mol. Microbiol. 48:1377-1387.
    • (2003) Mol. Microbiol , vol.48 , pp. 1377-1387
    • Kraus, P.R.1    Fox, D.S.2    Cox, G.M.3    Heitman, J.4
  • 38
    • 0034615701 scopus 로고    scopus 로고
    • Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation
    • Lewis, J., A. Devin, A. Miller, Y. Lin, Y. Rodriguez, L. Neckers, and Z. G. Liu. 2000. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J. Biol. Chem. 275:10519-10526.
    • (2000) J. Biol. Chem , vol.275 , pp. 10519-10526
    • Lewis, J.1    Devin, A.2    Miller, A.3    Lin, Y.4    Rodriguez, Y.5    Neckers, L.6    Liu, Z.G.7
  • 39
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin- cyclosporin A and FKBP-FK506 complexes
    • Liu, J., J. Farmer, Jr., W. S. Lane, J. Friedman, I. Weissman, and S. L. Schreiber. 1991. Calcineurin is a common target of cyclophilin- cyclosporin A and FKBP-FK506 complexes. Cell 66:807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer Jr., J.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 40
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 41
    • 0030667206 scopus 로고    scopus 로고
    • A yeast mutant showing diagnostic markers of early and late apoptosis
    • Madeo, F., E. Frohlich, and K. U. Frohlich. 1997. A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol. 139:729-734.
    • (1997) J. Cell Biol , vol.139 , pp. 729-734
    • Madeo, F.1    Frohlich, E.2    Frohlich, K.U.3
  • 44
    • 18744382408 scopus 로고    scopus 로고
    • Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α
    • Marcu, M. G., M. Doyle, A. Bertolotti, D. Ron, L. Hendershot, and L. Neckers. 2002. Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α. Mol. Cell. Biol. 22:8506-8513.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 8506-8513
    • Marcu, M.G.1    Doyle, M.2    Bertolotti, A.3    Ron, D.4    Hendershot, L.5    Neckers, L.6
  • 45
    • 0031451194 scopus 로고    scopus 로고
    • Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae
    • Matheos, D. P., T. J. Kingsbury, U. S. Ahsan, and K. W. Cunningham. 1997. Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae. Genes Dev. 11:3445-3458.
    • (1997) Genes Dev , vol.11 , pp. 3445-3458
    • Matheos, D.P.1    Kingsbury, T.J.2    Ahsan, U.S.3    Cunningham, K.W.4
  • 46
  • 47
    • 0035282915 scopus 로고    scopus 로고
    • GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast
    • Mizunuma, M., D. Hirata, R. Miyaoka, and T. Miyakawa. 2001. GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast. EMBO J. 20:1074-1085.
    • (2001) EMBO J , vol.20 , pp. 1074-1085
    • Mizunuma, M.1    Hirata, D.2    Miyaoka, R.3    Miyakawa, T.4
  • 48
    • 33845609865 scopus 로고    scopus 로고
    • Mutual antagonism of target of rapamycin and calcineurin signaling
    • Mulet, J. M., D. E. Martin, R. Loewith, and M. N. Hall. 2006. Mutual antagonism of target of rapamycin and calcineurin signaling. J. Biol. Chem. 281:33000-33007.
    • (2006) J. Biol. Chem , vol.281 , pp. 33000-33007
    • Mulet, J.M.1    Martin, D.E.2    Loewith, R.3    Hall, M.N.4
  • 49
    • 0025836296 scopus 로고
    • Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2
    • Ohya, Y., H. Kawasaki, K. Suzuki, J. Londesborough, and Y. Anraku. 1991. Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2. J. Biol. Chem. 266:12784-12794.
    • (1991) J. Biol. Chem , vol.266 , pp. 12784-12794
    • Ohya, Y.1    Kawasaki, H.2    Suzuki, K.3    Londesborough, J.4    Anraku, Y.5
  • 50
    • 0025882163 scopus 로고
    • Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote
    • Pausch, M. H., D. Kaim, R. Kunisawa, A. Admon, and J. Thorner. 1991. Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote. EMBO J. 10:1511-1522.
    • (1991) EMBO J , vol.10 , pp. 1511-1522
    • Pausch, M.H.1    Kaim, D.2    Kunisawa, R.3    Admon, A.4    Thorner, J.5
  • 51
    • 0026591289 scopus 로고
    • Effects of fluconazole on the sterol and carbohydrate composition of four species of Candida
    • Pfaller, M., and J. Riley. 1992. Effects of fluconazole on the sterol and carbohydrate composition of four species of Candida. Eur. J. Clin. Microbiol. Infect. Dis. 11:152-156.
    • (1992) Eur. J. Clin. Microbiol. Infect. Dis , vol.11 , pp. 152-156
    • Pfaller, M.1    Riley, J.2
  • 53
    • 0036136901 scopus 로고    scopus 로고
    • AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation
    • Rabinovich, E., A. Kerem, K. U. Frohlich, N. Diamant, and S. Bar-Nun. 2002. AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. Mol. Cell. Biol. 22:626-634.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 626-634
    • Rabinovich, E.1    Kerem, A.2    Frohlich, K.U.3    Diamant, N.4    Bar-Nun, S.5
  • 54
    • 33749471267 scopus 로고    scopus 로고
    • Characterization of DNA damage in yeast apoptosis induced by hydrogen peroxide, acetic acid, and hyperosmotic shock
    • Ribeiro, G., M. Côrte-Real, and B. Johansson. 2006. Characterization of DNA damage in yeast apoptosis induced by hydrogen peroxide, acetic acid, and hyperosmotic shock. Mol. Biol. Cell 17:4584-4591.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4584-4591
    • Ribeiro, G.1    Côrte-Real, M.2    Johansson, B.3
  • 55
    • 33947241214 scopus 로고    scopus 로고
    • A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function
    • Roy, J., H. Li, P. Hogan, and M. Cyert. 2007. A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function. Mol. Cell 25:889-901.
    • (2007) Mol. Cell , vol.25 , pp. 889-901
    • Roy, J.1    Li, H.2    Hogan, P.3    Cyert, M.4
  • 56
    • 27644560976 scopus 로고    scopus 로고
    • Functional characterization of the Candida albicans CRZ1 gene encoding a calcineurin-regulated transcription factor
    • Santos, M., and I. F. de Larrinoa. 2005. Functional characterization of the Candida albicans CRZ1 gene encoding a calcineurin-regulated transcription factor. Curr. Genet. 48:88-100.
    • (2005) Curr. Genet , vol.48 , pp. 88-100
    • Santos, M.1    de Larrinoa, I.F.2
  • 57
    • 0037007151 scopus 로고    scopus 로고
    • Pheromone induces programmed cell death in S. cerevisiae
    • Severin, F. F., and A. A. Hyman. 2002. Pheromone induces programmed cell death in S. cerevisiae. Curr. Biol. 12:R233-R235.
    • (2002) Curr. Biol , vol.12
    • Severin, F.F.1    Hyman, A.A.2
  • 58
    • 0031438164 scopus 로고    scopus 로고
    • Calcineurin acts through the CRZ1/TCN1 encoded transcription factor to regulate gene expression in yeast
    • Stathopoulos, A. M., and M. S. Cyert. 1997. Calcineurin acts through the CRZ1/TCN1 encoded transcription factor to regulate gene expression in yeast. Genes Dev. 11:3432-3444.
    • (1997) Genes Dev , vol.11 , pp. 3432-3444
    • Stathopoulos, A.M.1    Cyert, M.S.2
  • 59
    • 34249069582 scopus 로고    scopus 로고
    • Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections
    • Steinbach, W. J., J. L. Reedy, R. A. Cramer, Jr., J. R. Perfect, and J. Heitman. 2007. Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat. Rev. Microbiol. 5:418-430.
    • (2007) Nat. Rev. Microbiol , vol.5 , pp. 418-430
    • Steinbach, W.J.1    Reedy, J.L.2    Cramer Jr., R.A.3    Perfect, J.R.4    Heitman, J.5
  • 60
    • 33746506061 scopus 로고    scopus 로고
    • The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation
    • Tabuchi, M., A. Audhya, A. B. Parsons, C. Boone, and S. D. Emr. 2006. The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol. Cell. Biol. 26:5861-5875.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 5861-5875
    • Tabuchi, M.1    Audhya, A.2    Parsons, A.B.3    Boone, C.4    Emr, S.D.5
  • 61
    • 34247892293 scopus 로고    scopus 로고
    • In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity
    • Truman, A., S. Millson, J. Nuttall, M. Mollapour, C. Prodromou, and P. Piper. 2007. In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity. Eukaryot. Cell 6:744-752.
    • (2007) Eukaryot. Cell , vol.6 , pp. 744-752
    • Truman, A.1    Millson, S.2    Nuttall, J.3    Mollapour, M.4    Prodromou, C.5    Piper, P.6
  • 62
    • 33846285777 scopus 로고    scopus 로고
    • Caspases in yeast apoptosis-like death: Facts and artefacts
    • Váchová, L., and Z. Palková. 2007. Caspases in yeast apoptosis-like death: facts and artefacts. FEMS Yeast Res. 7:12-21.
    • (2007) FEMS Yeast Res , vol.7 , pp. 12-21
    • Váchová, L.1    Palková, Z.2
  • 63
    • 6344278689 scopus 로고    scopus 로고
    • Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae
    • Viladevall, L., R. Serrano, A. Ruiz, G. Domenech, J. Giraldo, A. Barcelo, and J. Arino. 2004. Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J. Biol. Chem. 279:43614-43624.
    • (2004) J. Biol. Chem , vol.279 , pp. 43614-43624
    • Viladevall, L.1    Serrano, R.2    Ruiz, A.3    Domenech, G.4    Giraldo, J.5    Barcelo, A.6    Arino, J.7
  • 64
    • 0024324482 scopus 로고
    • A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase
    • Wallis, J. W., G. Chrebet, G. Brodsky, M. Rolfe, and R. Rothstein. 1989. A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase. Cell 58:409-419.
    • (1989) Cell , vol.58 , pp. 409-419
    • Wallis, J.W.1    Chrebet, G.2    Brodsky, G.3    Rolfe, M.4    Rothstein, R.5
  • 65
    • 0035796626 scopus 로고    scopus 로고
    • The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p
    • Williams, K. E., and M. S. Cyert. 2001. The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p. EMBO J. 20:3473-3483.
    • (2001) EMBO J , vol.20 , pp. 3473-3483
    • Williams, K.E.1    Cyert, M.S.2
  • 66
    • 3543068246 scopus 로고    scopus 로고
    • Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species
    • Wysocki, R., and S. J. Kron. 2004. Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species. J. Cell Biol. 166:311-316.
    • (2004) J. Cell Biol , vol.166 , pp. 311-316
    • Wysocki, R.1    Kron, S.J.2
  • 67
    • 0033911935 scopus 로고    scopus 로고
    • Assays for studying Bax-induced lethality in the yeast Saccharomyces cerevisiae
    • Xu, Q., N. Ke, S. Matsuyama, and J. C. Reed. 2000. Assays for studying Bax-induced lethality in the yeast Saccharomyces cerevisiae. Methods Enzymol. 322:283-296.
    • (2000) Methods Enzymol , vol.322 , pp. 283-296
    • Xu, Q.1    Ke, N.2    Matsuyama, S.3    Reed, J.C.4
  • 68
    • 0035818999 scopus 로고    scopus 로고
    • The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
    • Ye, Y., H. H. Meyer, and T. A. Rapoport. 2001. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414:652-656.
    • (2001) Nature , vol.414 , pp. 652-656
    • Ye, Y.1    Meyer, H.H.2    Rapoport, T.A.3
  • 69
    • 0023134858 scopus 로고
    • Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes
    • Yoshida, Y., and Y. Aoyama. 1987. Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes. Biochem. Pharmacol. 36:229-235.
    • (1987) Biochem. Pharmacol , vol.36 , pp. 229-235
    • Yoshida, Y.1    Aoyama, Y.2
  • 70
    • 0037163129 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae
    • Yoshimoto, H., K. Saltsman, A. P. Gasch, H. X. Li, N. Ogawa, D. Botstein, P. O. Brown, and M. S. Cyert. 2002. Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. J. Biol. Chem. 277:31079-31088.
    • (2002) J. Biol. Chem , vol.277 , pp. 31079-31088
    • Yoshimoto, H.1    Saltsman, K.2    Gasch, A.P.3    Li, H.X.4    Ogawa, N.5    Botstein, D.6    Brown, P.O.7    Cyert, M.S.8
  • 71
    • 33746628909 scopus 로고    scopus 로고
    • Multiple signaling pathways regulate yeast cell death during the response to mating pheromones
    • Zhang, N. N., D. D. Dudgeon, S. Paliwal, A. Levchenko, E. Grote, and K. W. Cunningham. 2006. Multiple signaling pathways regulate yeast cell death during the response to mating pheromones. Mol. Biol. Cell 17:3409-3422.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3409-3422
    • Zhang, N.N.1    Dudgeon, D.D.2    Paliwal, S.3    Levchenko, A.4    Grote, E.5    Cunningham, K.W.6
  • 72
    • 84934439633 scopus 로고    scopus 로고
    • Molecular interaction network of the Hsp90 chaperone system
    • Zhao, R., and W. Houry. 2007. Molecular interaction network of the Hsp90 chaperone system. Adv. Exp. Med. Biol. 594:27-36.
    • (2007) Adv. Exp. Med. Biol , vol.594 , pp. 27-36
    • Zhao, R.1    Houry, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.