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Volumn 44, Issue 3, 2000, Pages 739-746

Synergistic antifungal activities of bafilomycin A1, fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; AMPHOTERICIN B; ANTIFUNGAL AGENT; BAFILOMYCIN A1; CALCINEURIN; CASPOFUNGIN; CYCLOSPORIN; CYCLOSPORIN DERIVATIVE; FLUCONAZOLE; FLUCYTOSINE; L 685818; L 743873; MULTIDRUG RESISTANCE PROTEIN; PNEUMOCANDIN DERIVATIVE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; TACROLIMUS; UNCLASSIFIED DRUG;

EID: 0033998663     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.3.739-746.2000     Document Type: Article
Times cited : (154)

References (54)
  • 1
    • 0026722491 scopus 로고
    • Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype
    • Arceri, R. J., K. Stieglitz, and B. E. Bierer. 1992. Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. Blood 80:1528-1536.
    • (1992) Blood , vol.80 , pp. 1528-1536
    • Arceri, R.J.1    Stieglitz, K.2    Bierer, B.E.3
  • 2
    • 0011913143 scopus 로고
    • Bafilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells and plant cells
    • Bowman, E. J., A. Siebers, and K. Altendorf. 1988. Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells and plant cells. Proc. Natl. Acad. Sci. USA 85:7972-7976.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7972-7976
    • Bowman, E.J.1    Siebers, A.2    Altendorf, K.3
  • 4
    • 0028597938 scopus 로고
    • Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands
    • Cardenas, M., C. Hemenway, R. S. Muir, R. Ye, D. Florentino, and J. Heitman. 1994. Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. EMBO J. 13:5944-5957.
    • (1994) EMBO J. , vol.13 , pp. 5944-5957
    • Cardenas, M.1    Hemenway, C.2    Muir, R.S.3    Ye, R.4    Florentino, D.5    Heitman, J.6
  • 6
    • 0033043180 scopus 로고    scopus 로고
    • Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans
    • Cruz, M. C., L. M. Cavallo, J. M. Görlach, G. Cox, J. R. Perfect, M. E. Cardenas, and J. Heitman. 1999. Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans. Mol. Cell. Biol. 19:4101-4112.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4101-4112
    • Cruz, M.C.1    Cavallo, L.M.2    Görlach, J.M.3    Cox, G.4    Perfect, J.R.5    Cardenas, M.E.6    Heitman, J.7
  • 7
    • 0033986998 scopus 로고    scopus 로고
    • Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin
    • Cruz, M. C., M. Del Poeta, P. Wang, R. Wenger, G. Zenke, V. F. J. Quesniaux, N. R. Movva, J. R. Perfect, M. E. Cardenas, and J. Heitman. 2000. Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin. Antimicrob. Agents Chemother. 44:143-149.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 143-149
    • Cruz, M.C.1    Del Poeta, M.2    Wang, P.3    Wenger, R.4    Zenke, G.5    Quesniaux, V.F.J.6    Movva, N.R.7    Perfect, J.R.8    Cardenas, M.E.9    Heitman, J.10
  • 8
    • 0033977390 scopus 로고    scopus 로고
    • Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans
    • Cruz, M. C., R. A. Sia, M. Olson, G. M. Cox, and J. Heitman. 2000. Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans. Infect. Immun. 68:982-985.
    • (2000) Infect. Immun. , vol.68 , pp. 982-985
    • Cruz, M.C.1    Sia, R.A.2    Olson, M.3    Cox, G.M.4    Heitman, J.5
  • 9
    • 0030854825 scopus 로고    scopus 로고
    • In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds
    • Del Poeta, M., W. A. Schell, and J. R. Perfect. 1997. In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds. Antimicrob. Agents Chemother. 41:1835-1836.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1835-1836
    • Del Poeta, M.1    Schell, W.A.2    Perfect, J.R.3
  • 11
    • 0028568052 scopus 로고
    • The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase
    • Douglas, C. M., F. Foor, J. A. Marrinan, N. Morin, J. B. Nielsen, A. M. Dahi, P. Mazur, W. Baginsky, W. Li, et al. 1994. The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. Proc. Natl. Acad. Sci. USA 20:12907-12911.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.20 , pp. 12907-12911
    • Douglas, C.M.1    Foor, F.2    Marrinan, J.A.3    Morin, N.4    Nielsen, J.B.5    Dahi, A.M.6    Mazur, P.7    Baginsky, W.8    Li, W.9
  • 12
    • 0040117958 scopus 로고    scopus 로고
    • Bafilomycins and concanamycin as inhibitors of V-ATPases and P-ATPases
    • Dröse, S., and K. Altendorf. 1997. Bafilomycins and concanamycin as inhibitors of V-ATPases and P-ATPases. J. Exp. Biol. 200:1-8.
    • (1997) J. Exp. Biol. , vol.200 , pp. 1-8
    • Dröse, S.1    Altendorf, K.2
  • 13
    • 0017594269 scopus 로고
    • Capsule size of Cryptococcus neoformans: Control and relationship to virulence
    • Dykstra, M. A., L. Friedman, and J. W. Murphy. 1977. Capsule size of Cryptococcus neoformans: control and relationship to virulence. Infect. Immun. 16:129-135.
    • (1977) Infect. Immun. , vol.16 , pp. 129-135
    • Dykstra, M.A.1    Friedman, L.2    Murphy, J.W.3
  • 14
    • 0031905588 scopus 로고    scopus 로고
    • Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-hinding cassette multidrug resistance transporter
    • Egner, R., F. E. Rosenthal, A. Kralli, D. Sanglard, and K. Kuchler. 1998. Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-hinding cassette multidrug resistance transporter. Mol. Biol. Cell 9:523-543.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 523-543
    • Egner, R.1    Rosenthal, F.E.2    Kralli, A.3    Sanglard, D.4    Kuchler, K.5
  • 15
    • 0028556290 scopus 로고
    • The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin a hypersensitivity and calcineurin-dependent growth
    • Eng, W. K., L. Faucette, M. M. McLaughlin, R. Cafferkey, Y. Koltin, R. A. Morris, P. R. Young, R. K. Johnson, and G. P. Livi. 1994. The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth. Gene 151:61-71.
    • (1994) Gene , vol.151 , pp. 61-71
    • Eng, W.K.1    Faucette, L.2    McLaughlin, M.M.3    Cafferkey, R.4    Koltin, Y.5    Morris, R.A.6    Young, P.R.7    Johnson, R.K.8    Livi, G.P.9
  • 16
    • 0031039601 scopus 로고    scopus 로고
    • Pneumocandin L-743,872 enhances the activities of amphotericin B and fluconazole against Cryptococcus neoformans in vitro
    • Franzot, S. P., and A. Casadevall. 1997. Pneumocandin L-743,872 enhances the activities of amphotericin B and fluconazole against Cryptococcus neoformans in vitro. Antimicrob. Agents Chemother. 41:331-336.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 331-336
    • Franzot, S.P.1    Casadevall, A.2
  • 19
    • 0028805462 scopus 로고
    • Vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly
    • Hemenway, C. S., K. Dolinski, M. E. Cardenas, M. A. Hiller, E. W. Jones, and J. Heitman. 1995. vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. Genetics 141:833-844.
    • (1995) Genetics , vol.141 , pp. 833-844
    • Hemenway, C.S.1    Dolinski, K.2    Cardenas, M.E.3    Hiller, M.A.4    Jones, E.W.5    Heitman, J.6
  • 21
    • 0027528403 scopus 로고
    • Reversion of the P-glycoprotein-mediated multidrug resistance of cancer cells by FK506 derivatives
    • Jachez, B., D. Boesch, M. A. Grassberger, and F. Loor. 1993. Reversion of the P-glycoprotein-mediated multidrug resistance of cancer cells by FK506 derivatives. Anticancer Drugs 4:223-229.
    • (1993) Anticancer Drugs , vol.4 , pp. 223-229
    • Jachez, B.1    Boesch, D.2    Grassberger, M.A.3    Loor, F.4
  • 22
    • 0032051455 scopus 로고    scopus 로고
    • Calcineurin subunit B is required for normal vegetative growth in Neurospora crassa
    • Kothe, G. O., and S. J. Free. 1998. Calcineurin subunit B is required for normal vegetative growth in Neurospora crassa. Fungal Genet. Biol. 23:248-258.
    • (1998) Fungal Genet. Biol. , vol.23 , pp. 248-258
    • Kothe, G.O.1    Free, S.J.2
  • 24
    • 0020316973 scopus 로고
    • Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice
    • Kwon-Chung, K. J., I. Polacheck, and T. J. Popkin. 1982. Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J. Bacteriol. 150:1414-1421.
    • (1982) J. Bacteriol. , vol.150 , pp. 1414-1421
    • Kwon-Chung, K.J.1    Polacheck, I.2    Popkin, T.J.3
  • 25
    • 0030780263 scopus 로고    scopus 로고
    • +, a Schizosaccharomyces pombe gene homolog of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B
    • +, a Schizosaccharomyces pombe gene homolog of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B. J. Bacteriol. 179:7653-7662.
    • (1997) J. Bacteriol. , vol.179 , pp. 7653-7662
    • Ishiguro, J.1    Saitou, A.2    Durán, A.3    Ribas, J.C.4
  • 26
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu, J., J. D. Farmer, W. S. Lane, J. Friedman, I. Weissman, et al. 1991. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5
  • 28
  • 29
    • 0028786641 scopus 로고
    • Cryptococcosis in the era of AIDS -100 years after the discovery of Cryptococcus neoformans
    • Mitchell, T. G., and J. R. Perfect. 1995. Cryptococcosis in the era of AIDS -100 years after the discovery of Cryptococcus neoformans. Clin. Microbiol. Rev. 8:515-548.
    • (1995) Clin. Microbiol. Rev. , vol.8 , pp. 515-548
    • Mitchell, T.G.1    Perfect, J.R.2
  • 30
    • 0026561219 scopus 로고
    • Modulation of multidrug resistance by immunosuppressive agents: Cyclosporin analogues, FK506 and mizoribine
    • Mizuno, K., Y. Furuhashi, T. Misawa, M. Iwata, M. Kawai, F. Kikkawa, T. Kano, and Y. Tomoda. 1992. Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. Anticancer Res. 12:21-25.
    • (1992) Anticancer Res. , vol.12 , pp. 21-25
    • Mizuno, K.1    Furuhashi, Y.2    Misawa, T.3    Iwata, M.4    Kawai, M.5    Kikkawa, F.6    Kano, T.7    Tomoda, Y.8
  • 31
    • 0028219602 scopus 로고
    • Modeling a conformationally sensitive region of the membrane sector of the fungal plasma membrane proton pump
    • Monk, B. C., W. C. Feng, C. J. Marshall, D. Seto-Young, S. Na, J. E. Haber, and D. S. Perlin. 1994. Modeling a conformationally sensitive region of the membrane sector of the fungal plasma membrane proton pump. J. Bioenerg. Biomembr. 26:101-115.
    • (1994) J. Bioenerg. Biomembr. , vol.26 , pp. 101-115
    • Monk, B.C.1    Feng, W.C.2    Marshall, C.J.3    Seto-Young, D.4    Na, S.5    Haber, J.E.6    Perlin, D.S.7
  • 32
    • 0028074994 scopus 로고
    • Fungal membrane proton pumps as promising new antifungal targets
    • Monk, B. C., and D. S. Perlin. 1994. Fungal membrane proton pumps as promising new antifungal targets. Crit. Rev. Microbiol. 20:209-223.
    • (1994) Crit. Rev. Microbiol. , vol.20 , pp. 209-223
    • Monk, B.C.1    Perlin, D.S.2
  • 33
    • 0027479079 scopus 로고
    • The α-mating type locus of Cryptococcus neoformans contains a peptide pheromone gene
    • Moore, T. D. E., and J. C. Edman. 1993. The α-mating type locus of Cryptococcus neoformans contains a peptide pheromone gene. Mol. Cell. Biol. 13:1962-1970.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1962-1970
    • Moore, T.D.E.1    Edman, J.C.2
  • 34
    • 0027263492 scopus 로고
    • Characterization of yeast plasma membrane H(+)-ATPase mutant pma1-A135V and its revertants
    • Na, S., D. S. Perlin, D. Seto-Young, G. Wang, and J. B. Haber. 1993. Characterization of yeast plasma membrane H(+)-ATPase mutant pma1-A135V and its revertants. J. Biol. Chem. 268:11792-11797.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11792-11797
    • Na, S.1    Perlin, D.S.2    Seto-Young, D.3    Wang, G.4    Haber, J.B.5
  • 36
    • 0027385382 scopus 로고
    • Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions
    • Nakamura, T., Y. Liu, D. Hirata, H. Namba, S. Harada, T. Hirokawa, and T. Miyakawa. 1993. Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions. EMBO J. 12:4063-4071.
    • (1993) EMBO J. , vol.12 , pp. 4063-4071
    • Nakamura, T.1    Liu, Y.2    Hirata, D.3    Namba, H.4    Harada, S.5    Hirokawa, T.6    Miyakawa, T.7
  • 38
    • 80051502274 scopus 로고    scopus 로고
    • In vitro growth-inhibitory activity of pneumocandins L-733,560 and L-743,872 against putatively amphotericin B- and fluconazole-resistant Candida isolates: Influence of assay conditions
    • Nelson, P. W., M. Lozano-Chiu, and J. H. Rex. 1996. In vitro growth-inhibitory activity of pneumocandins L-733,560 and L-743,872 against putatively amphotericin B- and fluconazole-resistant Candida isolates: influence of assay conditions. J. Med. Vet. Mycol. 35:285-287.
    • (1996) J. Med. Vet. Mycol. , vol.35 , pp. 285-287
    • Nelson, P.W.1    Lozano-Chiu, M.2    Rex, J.H.3
  • 39
    • 0031028176 scopus 로고    scopus 로고
    • The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein
    • Odom, A., M. Del Poeta, J. Perfect, and J. Heitman. 1997. The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein. Antimicrob. Agents Chemother. 41:156-161.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 156-161
    • Odom, A.1    Del Poeta, M.2    Perfect, J.3    Heitman, J.4
  • 40
    • 0031008864 scopus 로고    scopus 로고
    • Calcineurin is required for virulence of Cryptococcus neoformans
    • Odom, A., S. Muir, E. Lim, D. L. Toffaletti, J. Perfect, and J. Heitman. 1997. Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J. 16:2576-2589.
    • (1997) EMBO J. , vol.16 , pp. 2576-2589
    • Odom, A.1    Muir, S.2    Lim, E.3    Toffaletti, D.L.4    Perfect, J.5    Heitman, J.6
  • 41
    • 0021929967 scopus 로고
    • Effects of cyclosporine in experimental cryptococcal meningitis
    • Perfect, J. R., and D. T. Durack. 1985. Effects of cyclosporine in experimental cryptococcal meningitis. Infect. Immun. 50:22-26.
    • (1985) Infect. Immun. , vol.50 , pp. 22-26
    • Perfect, J.R.1    Durack, D.T.2
  • 42
    • 0027372019 scopus 로고
    • The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid
    • Perfect, J. R., D. L. Toffaletti, and T. H. Rude. 1993. The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid. Infect. Immun. 61:4446-4451.
    • (1993) Infect. Immun. , vol.61 , pp. 4446-4451
    • Perfect, J.R.1    Toffaletti, D.L.2    Rude, T.H.3
  • 43
    • 0031469834 scopus 로고    scopus 로고
    • The plasma membrane H(+)-ATPase of fungi. A candidate drug target?
    • Perlin, D. S., D. Seto-Young, and B. C. Monk. 1997. The plasma membrane H(+)-ATPase of fungi. A candidate drug target? Ann. N. Y. Acad. Sci. 834:609-617.
    • (1997) Ann. N. Y. Acad. Sci. , vol.834 , pp. 609-617
    • Perlin, D.S.1    Seto-Young, D.2    Monk, B.C.3
  • 45
    • 0028278253 scopus 로고
    • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans
    • Rasmussen, C., C. Garen, S. Brining, R. L. Kincaid, R. L. Means, and A. R. Means. 1994. The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. EMBO J. 13:2545-2552.
    • (1994) EMBO J. , vol.13 , pp. 2545-2552
    • Rasmussen, C.1    Garen, C.2    Brining, S.3    Kincaid, R.L.4    Means, R.L.5    Means, A.R.6
  • 46
    • 0027955136 scopus 로고
    • Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520
    • Raymond, M., S. Ruetz, D. Y. Thomas, and P. Gros. 1994. Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520. Mol. Cell. Biol. 14:277-286.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 277-286
    • Raymond, M.1    Ruetz, S.2    Thomas, D.Y.3    Gros, P.4
  • 47
    • 0020037577 scopus 로고
    • Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans
    • Rhodes, J. C., I. Polacheck, and K. J. Kwon-Chung. 1982. Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans. Infect. Immun. 36:1175-1184.
    • (1982) Infect. Immun. , vol.36 , pp. 1175-1184
    • Rhodes, J.C.1    Polacheck, I.2    Kwon-Chung, K.J.3
  • 48
    • 0029027674 scopus 로고
    • Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells
    • Sharom, J. F., X. Yu, J. W. K. Chu, and C. A. Doige. 1995. Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells. Biochem. J. 308:381-390.
    • (1995) Biochem. J. , vol.308 , pp. 381-390
    • Sharom, J.F.1    Yu, X.2    Chu, J.W.K.3    Doige, C.A.4
  • 51
    • 0030757452 scopus 로고    scopus 로고
    • In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species
    • Vazquez, J. A., M. E. Lynch, D. Boikov, and J. D. Sobel. 1997. In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species. Antimicrob. Agents Chemother. 41:1612-1614.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1612-1614
    • Vazquez, J.A.1    Lynch, M.E.2    Boikov, D.3    Sobel, J.D.4
  • 52
    • 0031748055 scopus 로고    scopus 로고
    • 2+/CaM-dependent phosphatase (calcineurin) is improved by mutation in URE2 or PMA1
    • 2+/CaM-dependent phosphatase (calcineurin) is improved by mutation in URE2 or PMA1. Genetics 149:865-878.
    • (1998) Genetics , vol.149 , pp. 865-878
    • Withee, J.L.1    Sen, R.2    Cyert, M.S.3
  • 53
    • 0028200722 scopus 로고
    • A calcineurin-like gene ppb1+ in fission yeast: Mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning
    • Yoshida, T., T. Toda, and M. Yanagida. 1994. A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning. J. Cell Sci. 107:1725-1735.
    • (1994) J. Cell Sci. , vol.107 , pp. 1725-1735
    • Yoshida, T.1    Toda, T.2    Yanagida, M.3
  • 54
    • 2642616985 scopus 로고    scopus 로고
    • Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin
    • Zhao, C., U. S. Jung, P. Garrett-Engele, T. Roe, M. S. Cyert, and D. E. Levin. 1998. Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin. Mol. Cell. Biol. 18:1013-1022.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1013-1022
    • Zhao, C.1    Jung, U.S.2    Garrett-Engele, P.3    Roe, T.4    Cyert, M.S.5    Levin, D.E.6


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