메뉴 건너뛰기




Volumn 32, Issue 12, 2008, Pages 2128-2135

Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine

Author keywords

Ethanol withdrawal syndrome; Hippocampal slice culture; Memantine; Toxicity

Indexed keywords

DIZOCILPINE; MEMANTINE;

EID: 57249116909     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2008.00801.x     Document Type: Article
Times cited : (34)

References (79)
  • 1
    • 44349135626 scopus 로고    scopus 로고
    • Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice cultures
    • Albus K, Wahab A, Heinemann U (2008) Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice cultures. Br J Pharmacol 154 : 709 724.
    • (2008) Br J Pharmacol , vol.154 , pp. 709-724
    • Albus, K.1    Wahab, A.2    Heinemann, U.3
  • 2
    • 14344253935 scopus 로고    scopus 로고
    • Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-zaspartate receptors in rat hippocampal neurons
    • Aracava Y, Pereira EF, Maelicke A, Albuquerque EX (2005) Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-zaspartate receptors in rat hippocampal neurons. J Pharmacol Exp Ther 312 : 1195 1205.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1195-1205
    • Aracava, Y.1    Pereira, E.F.2    Maelicke, A.3    Albuquerque, E.X.4
  • 3
    • 0023513549 scopus 로고
    • Ethanol and nitrous oxide produce withdrawal-induced convulsions by similar mechanisms in mice
    • Belknap JK, Laursen SE, Crabbe JC (1987) Ethanol and nitrous oxide produce withdrawal-induced convulsions by similar mechanisms in mice. Life Sci 41 : 2033 2040.
    • (1987) Life Sci , vol.41 , pp. 2033-2040
    • Belknap, J.K.1    Laursen, S.E.2    Crabbe, J.C.3
  • 4
    • 0035830652 scopus 로고    scopus 로고
    • Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat
    • Bienkowski P, Krzascik P, Koros E, Kostowski W, Scinska A, Danysz W (2001) Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat. Eur J Pharmacol 413 : 81 89.
    • (2001) Eur J Pharmacol , vol.413 , pp. 81-89
    • Bienkowski, P.1    Krzascik, P.2    Koros, E.3    Kostowski, W.4    Scinska, A.5    Danysz, W.6
  • 5
    • 0030627444 scopus 로고    scopus 로고
    • Expression of c-Fos protein immunoreactivity in rat brain during ethanol withdrawal is prevented by nifedipine
    • Bouchenafa O, Littleton JM (1998) Expression of c-Fos protein immunoreactivity in rat brain during ethanol withdrawal is prevented by nifedipine. Alcohol 15 : 71 76.
    • (1998) Alcohol , vol.15 , pp. 71-76
    • Bouchenafa, O.1    Littleton, J.M.2
  • 6
    • 0032796329 scopus 로고    scopus 로고
    • The diversity of seizures related to alcohol use. a study of consecutive patients
    • Brathen G, Brodtkorb E, Helde G, Sand T, Bovim G (1999) The diversity of seizures related to alcohol use. A study of consecutive patients. Eur J Neurol 6 : 697 703.
    • (1999) Eur J Neurol , vol.6 , pp. 697-703
    • Brathen, G.1    Brodtkorb, E.2    Helde, G.3    Sand, T.4    Bovim, G.5
  • 7
    • 0029001708 scopus 로고
    • Different binding affinities of NMDA receptor channel blockers in various brain regions - Indication of NMDA receptor heterogeneity
    • Bresink I, Danysz W, Parsons CG, Mutschler E (1995) Different binding affinities of NMDA receptor channel blockers in various brain regions - indication of NMDA receptor heterogeneity. Neuropharmacology 34 : 533 540.
    • (1995) Neuropharmacology , vol.34 , pp. 533-540
    • Bresink, I.1    Danysz, W.2    Parsons, C.G.3    Mutschler, E.4
  • 8
    • 0031020568 scopus 로고    scopus 로고
    • Chronic ethanol administration regulates the expression of GABAA receptor α1 and α5 subunits in the ventral tegmental area and hippocampus
    • Charlton ME, Sweetnam PM, Fitzgerald LW, Terwilliger RZ, Nestler EJ, Duman RS (1997) Chronic ethanol administration regulates the expression of GABAA receptor α1 and α5 subunits in the ventral tegmental area and hippocampus. J Neurochem 68 : 121 127.
    • (1997) J Neurochem , vol.68 , pp. 121-127
    • Charlton, M.E.1    Sweetnam, P.M.2    Fitzgerald, L.W.3    Terwilliger, R.Z.4    Nestler, E.J.5    Duman, R.S.6
  • 9
    • 0031034905 scopus 로고    scopus 로고
    • Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: Uncompetitive antagonism
    • Chen HS, Lipton SA (1997) Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. J Physiol 499 : 27 46.
    • (1997) J Physiol , vol.499 , pp. 27-46
    • Chen, H.S.1    Lipton, S.A.2
  • 10
    • 0018385619 scopus 로고
    • Antagonism of the enhanced susceptibility to audiogenic seizures during alcohol withdrawal in the rat by gamma-aminobutyric acid (GABA) and "gABA-mimetic" agents
    • Cooper BR, Viik K, Ferris RM, White HL (1979) Antagonism of the enhanced susceptibility to audiogenic seizures during alcohol withdrawal in the rat by gamma-aminobutyric acid (GABA) and "GABA-mimetic" agents. J Pharmacol Exp Ther 209 : 396 403.
    • (1979) J Pharmacol Exp Ther , vol.209 , pp. 396-403
    • Cooper, B.R.1    Viik, K.2    Ferris, R.M.3    White, H.L.4
  • 12
    • 0025760052 scopus 로고
    • Effects of convulsants on handling-induced convulsions in mice selected for ethanol withdrawal severity
    • Crabbe JC, Merrill CD, Belknap JK (1991) Effects of convulsants on handling-induced convulsions in mice selected for ethanol withdrawal severity. Brain Res 550 : 1 6.
    • (1991) Brain Res , vol.550 , pp. 1-6
    • Crabbe, J.C.1    Merrill, C.D.2    Belknap, J.K.3
  • 14
    • 0027478922 scopus 로고
    • Increased sensitivity of the hippocampus in ethanol-dependent rats to toxic effect of N-methyl-D-aspartic acid in vivo
    • Davidson MD, Wilce P, Shanley BC (1993) Increased sensitivity of the hippocampus in ethanol-dependent rats to toxic effect of N-methyl-D-aspartic acid in vivo. Brain Res 606 : 5 9.
    • (1993) Brain Res , vol.606 , pp. 5-9
    • Davidson, M.D.1    Wilce, P.2    Shanley, B.C.3
  • 15
    • 0036811384 scopus 로고    scopus 로고
    • Altered responses to dizocilpine maleate administration in ethanol-withdrawn male and female rats
    • Devaud LL, Bartoo G, Malthankar G (2002) Altered responses to dizocilpine maleate administration in ethanol-withdrawn male and female rats. Alcohol 28 : 83 93.
    • (2002) Alcohol , vol.28 , pp. 83-93
    • Devaud, L.L.1    Bartoo, G.2    Malthankar, G.3
  • 16
    • 0032756836 scopus 로고    scopus 로고
    • Gender impacts behavioral and neurochemical adaptations in ethanol-dependent rats
    • Devaud LL, Matthews DB, Morrow AL (1999) Gender impacts behavioral and neurochemical adaptations in ethanol-dependent rats. Pharmacol Biochem Behav 64 : 841 849.
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 841-849
    • Devaud, L.L.1    Matthews, D.B.2    Morrow, A.L.3
  • 17
    • 0032891904 scopus 로고    scopus 로고
    • Gender-selective effects of ethanol dependence on NMDA receptor subunit expression in cerebral cortex, hippocampus and hypothalamus
    • Devaud LL, Morrow AL (1999) Gender-selective effects of ethanol dependence on NMDA receptor subunit expression in cerebral cortex, hippocampus and hypothalamus. Eur J Pharmacol 369 : 331 334.
    • (1999) Eur J Pharmacol , vol.369 , pp. 331-334
    • Devaud, L.L.1    Morrow, A.L.2
  • 18
    • 0023141024 scopus 로고
    • Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence
    • Dolin S, Little H, Hudspith M, Pagonis C, Littleton J (1987) Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence. Neuropharmacology 26 : 275 279.
    • (1987) Neuropharmacology , vol.26 , pp. 275-279
    • Dolin, S.1    Little, H.2    Hudspith, M.3    Pagonis, C.4    Littleton, J.5
  • 20
    • 0031688235 scopus 로고    scopus 로고
    • Chronic ethanol consumption: From neuroadaptation to neurodegeneration
    • Fadda F, Rossetti ZL (1998) Chronic ethanol consumption: from neuroadaptation to neurodegeneration. Prog Neurobiol 56 : 385 431.
    • (1998) Prog Neurobiol , vol.56 , pp. 385-431
    • Fadda, F.1    Rossetti, Z.L.2
  • 21
    • 0034705729 scopus 로고    scopus 로고
    • Decreased GABA and increased glutamate receptor-mediated activity on inferior colliculus neurons in vitro are associated with susceptibility to ethanol withdrawal seizures
    • Faingold CL, Li Y, Evans MS (2000) Decreased GABA and increased glutamate receptor-mediated activity on inferior colliculus neurons in vitro are associated with susceptibility to ethanol withdrawal seizures. Brain Res 868 : 287 295.
    • (2000) Brain Res , vol.868 , pp. 287-295
    • Faingold, C.L.1    Li, Y.2    Evans, M.S.3
  • 22
    • 0028946579 scopus 로고
    • Ethanol withdrawal induces increased firing in inferior colliculus neuronsassociated with audiogenic seizure susceptibility
    • Faingold CL, Riaz A (1995) Ethanol withdrawal induces increased firing in inferior colliculus neuronsassociated with audiogenic seizure susceptibility. Exp Neurol 132 : 91 98.
    • (1995) Exp Neurol , vol.132 , pp. 91-98
    • Faingold, C.L.1    Riaz, A.2
  • 23
    • 37449009393 scopus 로고    scopus 로고
    • Topiramate (Topamax) reduces conditioned abstinence behaviours and handling-induced convulsions (HIC) after chronic administration of alcohol in Swiss-Webster mice
    • Farook JM, Morrell DJ, Lewis B, Littleton JM, Barron S (2007) Topiramate (Topamax) reduces conditioned abstinence behaviours and handling-induced convulsions (HIC) after chronic administration of alcohol in Swiss-Webster mice. Alcohol Alcohol 42 : 296 300.
    • (2007) Alcohol Alcohol , vol.42 , pp. 296-300
    • Farook, J.M.1    Morrell, D.J.2    Lewis, B.3    Littleton, J.M.4    Barron, S.5
  • 24
    • 0038814240 scopus 로고    scopus 로고
    • Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices
    • Ferchmin PA, Perez D, Eterovic VA, de Vellis J (2003) Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices. J Pharmacol Exp Ther 305 : 1071 1078.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 1071-1078
    • Ferchmin, P.A.1    Perez, D.2    Eterovic, V.A.3    De Vellis, J.4
  • 26
    • 0037382253 scopus 로고    scopus 로고
    • γ-Hydroxybutyric acid and diazepam antagonize a rapid increase in GABAA receptors α4 subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells
    • Follesa P, Mancuso L, Biggio F, Mostallino MC, Manca A, Mascia MP, Busonero F, Talani G, Sanna E, Biggio G (2003) γ-Hydroxybutyric acid and diazepam antagonize a rapid increase in GABAA receptors α4 subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells. Mol Pharmacol 63 : 896 907.
    • (2003) Mol Pharmacol , vol.63 , pp. 896-907
    • Follesa, P.1    Mancuso, L.2    Biggio, F.3    Mostallino, M.C.4    Manca, A.5    Mascia, M.P.6    Busonero, F.7    Talani, G.8    Sanna, E.9    Biggio, G.10
  • 27
    • 0022609086 scopus 로고
    • GABAergic modulation of inferior colliculus excitability: Role in the ethanol withdrawal audiogenic seizures
    • Frye GD, McCown TJ, Breese GR, Peterson SL (1986) GABAergic modulation of inferior colliculus excitability: role in the ethanol withdrawal audiogenic seizures. J Pharmacol Exp Ther 237 : 478 485.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 478-485
    • Frye, G.D.1    McCown, T.J.2    Breese, G.R.3    Peterson, S.L.4
  • 29
    • 0015228723 scopus 로고
    • Alcohol dependence produced in mice by inhalation of ethanol: Grading the withdrawal reaction
    • Goldstein DB, Pal N (1971) Alcohol dependence produced in mice by inhalation of ethanol: grading the withdrawal reaction. Science 172 : 288 290.
    • (1971) Science , vol.172 , pp. 288-290
    • Goldstein, D.B.1    Pal, N.2
  • 30
    • 0024788711 scopus 로고
    • Spontaneous versus elicited seizures following ethanol withdrawal: Differential time course
    • Gonzalez LP, Czachura JF, Brewer KW (1989) Spontaneous versus elicited seizures following ethanol withdrawal: differential time course. Alcohol 6 : 481 487.
    • (1989) Alcohol , vol.6 , pp. 481-487
    • Gonzalez, L.P.1    Czachura, J.F.2    Brewer, K.W.3
  • 31
    • 0028177044 scopus 로고
    • The 5-HT3 antagonist MDL-72222 exacerbates ethanol withdrawal seizures in mice
    • Grant KA, Hellevuo K, Tabakoff B (1994) The 5-HT3 antagonist MDL-72222 exacerbates ethanol withdrawal seizures in mice. Alcohol Clin Exp Res 18 : 410 414.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 410-414
    • Grant, K.A.1    Hellevuo, K.2    Tabakoff, B.3
  • 33
    • 10744224826 scopus 로고    scopus 로고
    • The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors
    • Harris BR, Gibson DA, Prendergast MA, Blanchard JA, Holley RC, Hart SR, Scotland RL, Foster TC, Pedigo NW, Littleton JM (2003) The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors. Alcohol Clin Exp Res 27 : 1724 1735.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 1724-1735
    • Harris, B.R.1    Gibson, D.A.2    Prendergast, M.A.3    Blanchard, J.A.4    Holley, R.C.5    Hart, S.R.6    Scotland, R.L.7    Foster, T.C.8    Pedigo, N.W.9    Littleton, J.M.10
  • 34
    • 0030011343 scopus 로고    scopus 로고
    • Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system
    • Hodges H, Sowinski P, Turner JJ, Fletcher A (1996) Comparison of the effects of the 5-HT3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system. Psychopharmacology (Berl) 125 : 146 161.
    • (1996) Psychopharmacology (Berl) , vol.125 , pp. 146-161
    • Hodges, H.1    Sowinski, P.2    Turner, J.J.3    Fletcher, A.4
  • 35
    • 0027076781 scopus 로고
    • Chronic exposure of cerebellar granule cells to ethanol results in increased N-methyl-D-aspartate receptor function
    • Iorio KR, Reinlib L, Tabakoff B, Hoffman PL (1992) Chronic exposure of cerebellar granule cells to ethanol results in increased N-methyl-D-aspartate receptor function. Mol Pharmacol 41 : 1142 1148.
    • (1992) Mol Pharmacol , vol.41 , pp. 1142-1148
    • Iorio, K.R.1    Reinlib, L.2    Tabakoff, B.3    Hoffman, P.L.4
  • 37
    • 0034016489 scopus 로고    scopus 로고
    • Sex differences in nicotine substitution to a pentylenetetrazol discriminative stimulus during ethanol withdrawal in rats
    • Jung ME, Wallis CJ, Gatch MB, Lal H (2000) Sex differences in nicotine substitution to a pentylenetetrazol discriminative stimulus during ethanol withdrawal in rats. Psychopharmacology (Berl) 149 : 235 240.
    • (2000) Psychopharmacology (Berl) , vol.149 , pp. 235-240
    • Jung, M.E.1    Wallis, C.J.2    Gatch, M.B.3    Lal, H.4
  • 38
    • 34248180627 scopus 로고    scopus 로고
    • NMDA receptor antagonists: Tools in neuroscience with promise for treating CNS pathologies
    • Kohr G (2007) NMDA receptor antagonists: tools in neuroscience with promise for treating CNS pathologies. J Physiol 581 : 1 2.
    • (2007) J Physiol , vol.581 , pp. 1-2
    • Kohr, G.1
  • 39
    • 18844447761 scopus 로고    scopus 로고
    • A comparison of the predictive therapeutic and undesired side-effects of the NMDA receptor antagonist, memantine, in mice
    • Kos T, Popik P (2005) A comparison of the predictive therapeutic and undesired side-effects of the NMDA receptor antagonist, memantine, in mice. Behav Pharmacol 16 : 155 161.
    • (2005) Behav Pharmacol , vol.16 , pp. 155-161
    • Kos, T.1    Popik, P.2
  • 40
    • 0027337472 scopus 로고
    • The abilities of 5-HT3 receptor antagonist ICS 205-930 to inhibit alcohol preference and withdrawal seizures in rats
    • Kostowski W, Dyr W, Krzascik P (1993) The abilities of 5-HT3 receptor antagonist ICS 205-930 to inhibit alcohol preference and withdrawal seizures in rats. Alcohol 10 : 369 373.
    • (1993) Alcohol , vol.10 , pp. 369-373
    • Kostowski, W.1    Dyr, W.2    Krzascik, P.3
  • 41
    • 0035069776 scopus 로고    scopus 로고
    • NMDA antagonists inhibit the development of ethanol dependence in rats
    • Kotlinska J (2001) NMDA antagonists inhibit the development of ethanol dependence in rats. Pol J Pharmacol 53 : 47 50.
    • (2001) Pol J Pharmacol , vol.53 , pp. 47-50
    • Kotlinska, J.1
  • 43
    • 0035898280 scopus 로고    scopus 로고
    • Post-insult activity is a major cause of delayed neuronal death in organotypic hippocampal slices exposed to glutamate
    • Lahtinen H, Autere A-M, Paalasmaa P, Lauri SE, Kaila K (2001) Post-insult activity is a major cause of delayed neuronal death in organotypic hippocampal slices exposed to glutamate. Neuroscience 105 : 131 137.
    • (2001) Neuroscience , vol.105 , pp. 131-137
    • Lahtinen, H.1    Autere, A.-M.2    Paalasmaa, P.3    Lauri, S.E.4    Kaila, K.5
  • 44
    • 0017298273 scopus 로고
    • Unusually high levels of blood alcohol?
    • Lindblad B, Olsson R (1976) Unusually high levels of blood alcohol? JAMA 236 : 1600 1602.
    • (1976) JAMA , vol.236 , pp. 1600-1602
    • Lindblad, B.1    Olsson, R.2
  • 45
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
    • Lipton SA (2006) Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat Rev Drug Discov 5 : 160 170.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 46
    • 1642474184 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotective drug development: Clinically tolerated NMDA receptor inhibition by memantine
    • Lipton SA, Chen HS (2004) Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine. Cell Death Differ 11 : 18 20.
    • (2004) Cell Death Differ , vol.11 , pp. 18-20
    • Lipton, S.A.1    Chen, H.S.2
  • 47
    • 0025162132 scopus 로고
    • Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; Doses required, stereospecificity and actions of Bay K 8644
    • Littleton JM, Little HJ, Whittington MA (1990) Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644. Psychopharmacology (Berl) 100 : 387 392.
    • (1990) Psychopharmacology (Berl) , vol.100 , pp. 387-392
    • Littleton, J.M.1    Little, H.J.2    Whittington, M.A.3
  • 48
    • 0026738256 scopus 로고
    • Role of neuronal calcium channels in ethanol dependence: From cell cultures to the intact animal
    • Littleton J, Little H, Laverty R (1992) Role of neuronal calcium channels in ethanol dependence: from cell cultures to the intact animal. Ann N Y Acad Sci 654 : 324 334.
    • (1992) Ann N Y Acad Sci , vol.654 , pp. 324-334
    • Littleton, J.1    Little, H.2    Laverty, R.3
  • 49
    • 0031011897 scopus 로고    scopus 로고
    • Chronic intermittent ethanol treatment in rats increases GABAA receptor α4-subunit expression: Possible relevance to alcohol dependence
    • Mahmoudi M, Kang MH, Taillakaratne N, Tobin AJ, Olsen RW (1997) Chronic intermittent ethanol treatment in rats increases GABAA receptor α4-subunit expression: possible relevance to alcohol dependence. J Neurochem 68 : 2485 2492.
    • (1997) J Neurochem , vol.68 , pp. 2485-2492
    • Mahmoudi, M.1    Kang, M.H.2    Taillakaratne, N.3    Tobin, A.J.4    Olsen, R.W.5
  • 51
    • 0035078242 scopus 로고    scopus 로고
    • Diazepam during prior ethanol withdrawals does not alter seizure susceptibility during a subsequent withdrawal
    • Mhatre MC, McKenzie SE, Gonzalez LP (2001) Diazepam during prior ethanol withdrawals does not alter seizure susceptibility during a subsequent withdrawal. Pharmacol Biochem Behav 68 : 339 346.
    • (2001) Pharmacol Biochem Behav , vol.68 , pp. 339-346
    • Mhatre, M.C.1    McKenzie, S.E.2    Gonzalez, L.P.3
  • 52
    • 0026089093 scopus 로고
    • Prolonged ethanol inhalation decreases γ-aminobutyric acidA receptor a subunit mRNAs in the rat cerebral cortex
    • Montpied P, Morrow AL, Karanian JW, Ginns EI, Martin BM, Paul SM (1991) Prolonged ethanol inhalation decreases γ-aminobutyric acidA receptor a subunit mRNAs in the rat cerebral cortex. Mol Pharmacol 39 : 157 163.
    • (1991) Mol Pharmacol , vol.39 , pp. 157-163
    • Montpied, P.1    Morrow, A.L.2    Karanian, J.W.3    Ginns, E.I.4    Martin, B.M.5    Paul, S.M.6
  • 53
    • 0027529578 scopus 로고
    • Time course of synaptic development in hippocampal organotypic cultures
    • Muller D, Buchs PA, Stoppini L (1993) Time course of synaptic development in hippocampal organotypic cultures. Brain Res Dev Brain Res 71 : 93 100.
    • (1993) Brain Res Dev Brain Res , vol.71 , pp. 93-100
    • Muller, D.1    Buchs, P.A.2    Stoppini, L.3
  • 54
    • 0030591455 scopus 로고    scopus 로고
    • Decreased GABA effectiveness in the inferior colliculus neurons during ethanol withdrawal in rats' susceptibility to audiogenic seizures
    • N'Gouemo P, Caspary DM, Faingold CL (1996) Decreased GABA effectiveness in the inferior colliculus neurons during ethanol withdrawal in rats' susceptibility to audiogenic seizures. Brain Res 724 : 200 204.
    • (1996) Brain Res , vol.724 , pp. 200-204
    • N'Gouemo, P.1    Caspary, D.M.2    Faingold, C.L.3
  • 55
    • 0034020488 scopus 로고    scopus 로고
    • Alcohol dependence at the cellular level: Effects of ethanol on calcium homeostasis of IM-9 human lymphoblast cells
    • Nagy J (2000) Alcohol dependence at the cellular level: effects of ethanol on calcium homeostasis of IM-9 human lymphoblast cells. J Stud Alcohol 61 : 225 231.
    • (2000) J Stud Alcohol , vol.61 , pp. 225-231
    • Nagy, J.1
  • 56
    • 57249115410 scopus 로고    scopus 로고
    • NIAAA (. Available at:. Accessed August 25, 2008.
    • NIAAA (2001-2002) NESARC. Available at: http://niaaa.census.gov/. Accessed August 25, 2008.
    • (2001) NESARC.
  • 57
    • 0012762083 scopus 로고    scopus 로고
    • NIAAA (. NIH Publication No. 96-4153. Bethesda, MD.
    • NIAAA (2001) Alcoholism: Getting the Facts. NIH Publication No. 96-4153. Bethesda, MD.
    • (2001) Alcoholism: Getting the Facts.
  • 58
    • 0027731677 scopus 로고
    • Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5- dimethyladamantan)
    • Parsons CG, Gruner R, Rozental J, Millar J, Lodge D (1993) Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan). Neuropharmacology 32 : 1337 1350.
    • (1993) Neuropharmacology , vol.32 , pp. 1337-1350
    • Parsons, C.G.1    Gruner, R.2    Rozental, J.3    Millar, J.4    Lodge, D.5
  • 59
    • 0027139605 scopus 로고
    • DAU 6215, a novel 5-HT3 receptor antagonist, improves performance in the aged rat in the Morris water maze task
    • Pitsikas N, Brambilla A, Borsini F (1993) DAU 6215, a novel 5-HT3 receptor antagonist, improves performance in the aged rat in the Morris water maze task. Neurobiol Aging 14 : 561 564.
    • (1993) Neurobiol Aging , vol.14 , pp. 561-564
    • Pitsikas, N.1    Brambilla, A.2    Borsini, F.3
  • 61
    • 0035208026 scopus 로고    scopus 로고
    • Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: Relation to distribution of the α7 nicotinic acetylcholine receptor subunit
    • Prendergast MA, Harris BR, Mayer S, Holley RC, Pauly JR, Littleton JM (2001) Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: relation to distribution of the α7 nicotinic acetylcholine receptor subunit. Med Sci Monit 7 : 1153 1160.
    • (2001) Med Sci Monit , vol.7 , pp. 1153-1160
    • Prendergast, M.A.1    Harris, B.R.2    Mayer, S.3    Holley, R.C.4    Pauly, J.R.5    Littleton, J.M.6
  • 62
    • 0033773037 scopus 로고    scopus 로고
    • Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro
    • Prendergast MA, Harris BR, Mayer S, Littleton JM (2000b) Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro. Alcohol Clin Exp Res 24 : 1583 1592.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1583-1592
    • Prendergast, M.A.1    Harris, B.R.2    Mayer, S.3    Littleton, J.M.4
  • 63
    • 1542380960 scopus 로고    scopus 로고
    • Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors
    • Prendergast MA, Harris BR, Mullholland PJ, Blanchard JA II., Gibson DA, Holley RC, Littleton JM (2004) Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors. Neuroscience 124 : 869 877.
    • (2004) Neuroscience , vol.124 , pp. 869-877
    • Prendergast, M.A.1    Harris, B.R.2    Mullholland, P.J.3    Blanchard II, J.A.4    Gibson, D.A.5    Holley, R.C.6    Littleton, J.M.7
  • 64
    • 0033769368 scopus 로고    scopus 로고
    • Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro
    • Pringle AK, Self J, Eshak M, Iannotti F (2000) Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro. Eur J Neurosci 12 : 3833 3842.
    • (2000) Eur J Neurosci , vol.12 , pp. 3833-3842
    • Pringle, A.K.1    Self, J.2    Eshak, M.3    Iannotti, F.4
  • 65
    • 0035933672 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner
    • Rammes G, Rupprecht R, Ferrari U, Zieglgansberger W, Parsons CG (2001) The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci Lett 306 : 81 84.
    • (2001) Neurosci Lett , vol.306 , pp. 81-84
    • Rammes, G.1    Rupprecht, R.2    Ferrari, U.3    Zieglgansberger, W.4    Parsons, C.G.5
  • 66
    • 0023871416 scopus 로고
    • Memantine (1-amino-3,5-dimethyladamantane) blocks the serotonin-induced depolarization response in a neuronal cell line
    • Reiser G, Binmoller FJ, Koch R (1988) Memantine (1-amino-3,5- dimethyladamantane) blocks the serotonin-induced depolarization response in a neuronal cell line. Brain Res 443 : 338 344.
    • (1988) Brain Res , vol.443 , pp. 338-344
    • Reiser, G.1    Binmoller, F.J.2    Koch, R.3
  • 67
    • 0029119866 scopus 로고
    • Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum
    • Rossetti ZL, Carboni S (1995) Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum. Eur J Pharmacol 283 : 177 183.
    • (1995) Eur J Pharmacol , vol.283 , pp. 177-183
    • Rossetti, Z.L.1    Carboni, S.2
  • 68
    • 0001870655 scopus 로고    scopus 로고
    • Introduction to alcohol withdrawal
    • Saitz R (1998) Introduction to alcohol withdrawal. Alcohol Health Res World 22 : 5 12.
    • (1998) Alcohol Health Res World , vol.22 , pp. 5-12
    • Saitz, R.1
  • 69
    • 0030614698 scopus 로고    scopus 로고
    • Dual mode of N-methyl-D-aspartate-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties
    • Sakaguchi T, Okada M, Kuno M, Kawasaki K (1997) Dual mode of N-methyl-D-aspartate-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties. Neuroscience 76 : 411 423.
    • (1997) Neuroscience , vol.76 , pp. 411-423
    • Sakaguchi, T.1    Okada, M.2    Kuno, M.3    Kawasaki, K.4
  • 71
    • 0037201945 scopus 로고    scopus 로고
    • Chronic multichannel recordings from organotypic hippocampal slice cultures: Protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists
    • Shimono K, Baudry M, Panchenko V, Taketani M (2002) Chronic multichannel recordings from organotypic hippocampal slice cultures: protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists. J Neurosci Methods 120 : 193 202.
    • (2002) J Neurosci Methods , vol.120 , pp. 193-202
    • Shimono, K.1    Baudry, M.2    Panchenko, V.3    Taketani, M.4
  • 72
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L, Buchs PA, Muller D (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37 : 173 182.
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 73
    • 0024452140 scopus 로고
    • Blood alcohol level among emergency room patients: A multivariate analysis
    • Teplin LA, Abram KM, Michaels SK (1989) Blood alcohol level among emergency room patients: a multivariate analysis. J Stud Alcohol 50 : 441 447.
    • (1989) J Stud Alcohol , vol.50 , pp. 441-447
    • Teplin, L.A.1    Abram, K.M.2    Michaels, S.K.3
  • 74
    • 0019797712 scopus 로고
    • Blood ethanol levels in sober alcohol users seen in an emergency room
    • Urso T, Gavaler JS, Van Thiel DH (1981) Blood ethanol levels in sober alcohol users seen in an emergency room. Life Sci 28 : 1053 1056.
    • (1981) Life Sci , vol.28 , pp. 1053-1056
    • Urso, T.1    Gavaler, J.S.2    Van Thiel, D.H.3
  • 75
    • 28844486050 scopus 로고    scopus 로고
    • Lorazepam and MK801 effects on behavioral and electrographic indices of alcohol withdrawal sensitization
    • Veatch LM, Becker HC (2005) Lorazepam and MK801 effects on behavioral and electrographic indices of alcohol withdrawal sensitization. Brain Res 1065 : 92 106.
    • (2005) Brain Res , vol.1065 , pp. 92-106
    • Veatch, L.M.1    Becker, H.C.2
  • 76
    • 33744500234 scopus 로고    scopus 로고
    • Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity
    • Volbracht C, van Beek J, Zhu C, Blomgren K, Leist M (2006) Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity. Eur J Neurosci 23 : 2611 2622.
    • (2006) Eur J Neurosci , vol.23 , pp. 2611-2622
    • Volbracht, C.1    Van Beek, J.2    Zhu, C.3    Blomgren, K.4    Leist, M.5
  • 77
    • 33749079039 scopus 로고    scopus 로고
    • Potential value of changes in cell markers in organotypic hippocampal cultures associated with chronic EtOH exposure and withdrawal: Comparison with NMDA-induced changes
    • Wilkins LH Jr., Prendergast MA, Blanchard J, Holley RC, Chambers ER, Littleton JM (2006) Potential value of changes in cell markers in organotypic hippocampal cultures associated with chronic EtOH exposure and withdrawal: comparison with NMDA-induced changes. Alcohol Clin Exp Res 30 : 1768 1780.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1768-1780
    • Wilkins Jr., L.H.1    Prendergast, M.A.2    Blanchard, J.3    Holley, R.C.4    Chambers, E.R.5    Littleton, J.M.6
  • 78
    • 0031808733 scopus 로고    scopus 로고
    • CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome
    • Wilson J, Little HJ (1998) CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome. Pharmacol Biochem Behav 59 : 967 973.
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 967-973
    • Wilson, J.1    Little, H.J.2
  • 79
    • 0033795839 scopus 로고    scopus 로고
    • Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures
    • Zimmer J, Kristensen BW, Jakobsen B, Noraberg J (2000) Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures. Amino Acids 19 : 7 21.
    • (2000) Amino Acids , vol.19 , pp. 7-21
    • Zimmer, J.1    Kristensen, B.W.2    Jakobsen, B.3    Noraberg, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.