Alcohol dependence at the cellular level: Effects of ethanol on calcium homeostasis of IM-9 human lymphoblast cells

Journal of Studies on Alcohol

Volumn 61, Issue 2, 2000, Pages 225-231

  Nagy, József ^a,b  

^a GEDEON RICHTER LTD   (Hungary)

^b National Institute for Alcohology   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CALCIUM; DIAZEPAM; HALOPERIDOL; VERAPAMIL;

ALCOHOLISM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; HUMAN; HUMAN CELL; LYMPHOBLAST;

EID: 0034020488     PISSN: 0096882X     EISSN: None     Source Type: Journal    
DOI: 10.15288/jsa.2000.61.225     Document Type: Article

References (23)

1. ANKARCRONA, M., DYPBUKT, J.M., BONFOCO, E., ZHIVOTOVSKY, B., ORRENIUS, S., LIPTON, S.A. AND NICOTERA, P. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15: 961-973, 1995.
2. BAFFY, G., VARGA, Z., FORIS, G. AND LEOVEY, A. Disturbed intracellular calcium-related processes of hepatocytes and neutrophils in human alcoholic liver disease. Clin. Biochem. 23: 241-245, 1990.
3. BUCK, K.J. AND HARRIS, R.A. Neuroadaptive responses to chronic ethanol. Alcsm Clin. Exp. Res. 15: 460-470, 1991.
4. CARMICKAEL, J., DEGRAFF, W.G., GAZDAR, A.F., MINNA, J.D. AND MITCHELL, J.B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of radiosensitivity. Cancer Res. 47: 943-946, 1987.
5. COVELLI, V., MUNNO, I., DECANDIA, P., ALTAMURA, M., CANNUSCIO, B., MAFFIONE, A.B. AND JIRILLO, E. Effects of benzodiazepines on the immune system. Acta Neurol. 13: 418-423, 1991.
6. CREWS, F.T., MORROW, A.L., CRISWELL, H. AND BREESE, G. Effects of ethanol on ion channels. Int. Rev. Neurobiol. 39: 283-367, 1996.
7. DUBOVSKY, S.L. AND FRANKS, R.D. Intracellular calcium ions in affective disorders: A review and an hypothesis. Biol. Psychiat. 18: 781-797, 1983.
8. GARZA, H.H., JR., MAYO, S., BOWEN, W.D., DECOSTA, B.R. AND CARR, D.J. Characterization of a (+)-azidophenazocine-sensitive sigma receptor on splenic lymphocytes. J. Immunol. 151: 4672-4680, 1993.
9. HOEK, J.B., TARASCI, T.F., HIGASHI, K., RUBIN, E. AND THOMAS, A.P. Phospholipasc C activation by ethanol in rat hepatocytes is unaffected by chronic ethanol feeding. Biochem J. 272: 59-64, 1990.
10. HOFFMAN, P.L. AND TABAKOFF, B. The role of the NMDA receptor in ethanol withdrawal. EXS 71: 61-70, 1994.
11. 2+)-ATPase inhibitor thapsigargin. Exp. Cell Res. 212: 84-92, 1994.
12. LITTEN, R.Z. AND ALLEN, J.P. Pharmacotherapies for alcoholism: Promising agents and clinical issues. Alcsm Clin. Exp. Res. 15: 620-633, 1991.
13. LITTLETON, J.M., LITTLE, H.J. AND WHITTINGTON, M.A. Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal: Doses required, stereospecificity and actions of Bay K 8644. Psychopharmacology 100: 387-392, 1990.
14. LIU, Y. AND WOLFE, S.A., JR. Haloperidol and spiperone potentiate murine splenic B cell proliferation. Immunopharmacology 34 (2-3): 147-159, 1996.
15. LOVINGER, D.M. Excitotoxicity and alcohol-related brain damage. Alcsm Clin. Exp. Res. 17: 19-27, 1993.
16. MARKOVITS, A., PREMECZ, G., LÖRINCZ, I., BAGI, G., NAGY, J., FARKAS, T. AND FÖLDES, I. Ethanol- induced signal transducing mechanism associated with a transient antiviral state in human amniotic cells. J. Stud. Alcohol 55: 495-502, 1994.
17. MILES, M.F., DIAZ, J.E. AND DEGUZMAN, V. Ethanol-responsive gene expression in neural cell cultures. Biochim. Biophys. Acta 1138: 268-274, 1992.
18. NAGY, J., KÖRNYEY, E. AND OROSZ, A. Increased intracellular calcium level in peripheral blood mononuclear cells of alcoholic patients under withdrawal. Drug Alcohol Depend. 32: 107-111, 1993.
19. ROCCA, P., BELLONE, G., BENNA, P., BERGAMASCO, B., RAVIZZA, L. AND FERRERO, P. Peripheral-type benzodiazepine receptors and diazepam binding inhibitor-like immunoreactivity distribution in human peripheral blood mononuclear cells. Immunopharmacology 25: 163-178, 1993.
20. ROSENBLOOM, A. Emerging treatment options in the alcohol withdrawal syndrome. J. Clin. Psychiat. 49 (Suppl. No. 12): 28-32, 1988.
21. SACERDOTE, P., CICILIATO, I.A., RUBBOLI, F. AND PANERAI, A.E. Effect of psychoactive drugs on lymphocyte neuropeptides. Ann. N. Y. Acad. Sci. 594: 270-279, 1990.
22. SCHLUMPE, M., PARMAR, R., RAMSEIER, H.R. AND LICHTENSTEIGER, W. Prenatal benzodiazepine immunosuppression: Possible involvement of peripheral benzodiazepine site. Devel. Pharmacol. Therapeut. 15 (3-4): 178-185, 1990.
23. TSIEN, R.Y., POZZAN, T. AND RINK, T.J. Calcium homeostasis in intact lymphocytes: Cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J. Cell Biol. 94: 325-334, 1982.