In vitro effects of ethanol withdrawal and spermidine on viability of hippocampus from male and female rat

Alcoholism: Clinical and Experimental Research

Volumn 24, Issue 12, 2000, Pages 1855-1861

  Prendergast, Mark A ^a   Harris, Barton R ^b   Blanchard II, John A ^b   Mayer, Sveta ^b   Alex Gibson, D ^b   Littleton, John M ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Cell Culture; Ethanol; Neurotoxicity; NMDA; Sex; Spermidine

Indexed keywords

ALCOHOL; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POLYAMINE; SPERMIDINE;

ALCOHOL WITHDRAWAL; ALCOHOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; INJURY SCALE; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEX DIFFERENCE;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0034538589     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2000.tb01990.x     Document Type: Article

References (64)

1. Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins
2. Visuospatial perception, construction and memory in alcoholism
3. Repeated ethanol withdrawal experience selectively alters sensitivity to different chemoconvulsant drugs in mice
4. The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems
5. Expression of c-FOS protein immunoreactivity in rat brain during ethanol withdrawal is prevented by nifedipine
6. N-(3aminopropyl)-cyclohexlamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo
7. The involvement of NMDA receptors in acute and chronic effects of ethanol
8. Chronic ethanol treatment leads to increased ornithine decarboxylase activity: Implications for a role of polyamines in ethanol dependence and withdrawal
9. Gender impacts behavioral and neurochemical adaptations in ethanol-dependent rats
10. Gender-selective effects of ethanol dependence on NMDA receptor subunit expression in cerebral cortex, hippocampus, and hypothalamus
11. Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence
12. Chronic ethanol consumption: From neuroadaptation to neurodegeneration
13. Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons
14. Ethanol and neurotransmitter interactions - From molecular to integrative effects
15. Dissociable cognitive impairments in problem drinkers
16. High blood alcohol levels in women: The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism
17. The effects of repeated withdrawal from alcohol on the memory of male and female alcoholics
18. The role of GABA(A) receptors in the acute and chronic effects of ethanol
19. Loss of vasopressin-immunoreactive neurons in alcoholics is dose-related and time-dependent
20. The effects of alcohol on the female brain: A neuropathological study
21. Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1
22. Chronic exposure of cerebellar granule cells to ethanol results in increased N-methyl-Daspartate receptor function
23. 2+: Developmental changes
24. Reduced cerebral gray matter observed in alcoholics using magnetic resonance imaging
25. Sex differences in nicotine substitution to a pentylenetetrazol discriminative stimulus during ethanol withdrawal in rats
26. Impaired spatial navigation in adult female but not adult male rats exposed to alcohol during the brain growth spurt
27. Ethanol opens G-protein-activated inwardly rectifying K+ channels
28. The cerebral cortex is damaged in chronic alcoholics
29. Role of neuronal calcium channels in ethanol dependence: From cell culture to the intact animal
30. Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal: Doses required, stereospecificity and actions of Bay K 8644
31. Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: Relation to the actions of ifenprodil
32. Nervous tissue growth and differentiation: Taurine effect on polyamine metabolism
33. Do women develop alcoholic brain damage more readily than men?
34. Ethanol climination in males and females: Relationship to menstrual cycle and body composition
35. Polyamine-enhanced NMDA receptor activity: Effects of ethanol
36. Prenatal ethanol exposure induces a sexually dimorphic effect on daily water consumption in prepubertal and adult rats
37. Protein kinase C epsilon mediates up-regulation of N-type calcium channels by ethanol
38. Effects of prenatal ethanol exposure on parvalbumin-expressing GABAergic neurons in the adult rat medial septum
39. Developmental change of the potentiation of NMDA response by spermine
40. 2+ signals in the somatic and dendritic regions of cerebellar Purkinjie neurons
41. In vivo pharmacological study of spermine-induced neurotoxicity
42. Chronic, but not acute, nicotine exposure attentuates ethanol withdrawal-induced hippocampal damage in vitro
43. Cognitive impairment and cerebral atrophy in 'heavy drinkers.' Prog Neuropsychopharmacol Biol Psychiatry
44. Seizures during ethanol withdrawal are blocked by focal microinjection of excitant amino acid antagonists into the inferior colliculus and pontine reticular formation
45. NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols
46. Protection of excitotoxic neuronal death by gluoconate through blockade of N-methyl-D-aspartate receptors
47. Dual mode of N-methyl-D-aspartate-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties
48. Spermine-induced toxicity in cerebellar granule neurons is independent of its actions at NMDA receptors
49. Role of ornithine decarboxylase and the polyamines in nervous system development: A review
50. Radioligand binding to the N-methyl-D-aspartate/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion
51. A simple method for organotypic cultures of nervous tissue
52. Anterior hippocampal volume deficits in nonamnesic, ageing chronic alcoholics
53. Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits
54. Differential sensitivity of NMDA receptor-mediated synaptic potentials to ethanol in immature versus mature hippocampus
55. Evidence for a causative role of N-methyl-D-aspartate receptors in an in vitro model of alcohol withdrawal hyperexcitability
56. Dynamics of NMDAR-mediated neurotoxicity during chronic ethanol exposure and withdrawal
57. MK-801 administration during ethanol withdrawal in neonatal rat pups attenuates ethanol-induced behavioral deficits
58. The role of glutamatergic neurotransmission in the pathophysiology of alcoholism
59. Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal
60. Repeated ethanol withdrawal produces site-dependent increases in EEG spiking
61. Correlation between increases in dihydropyridine binding in vivo and behavioral signs of ethanol withdrawal in mice
62. Modulation and block of ion channels: A new biology of polyamines
63. Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits