Lectinomics. II. A highway to biomedical/clinical diagnostics

Biotechnology Advances

Volumn 27, Issue 1, 2009, Pages 1-15

  Gemeiner, Peter ^a   Mislovičová, Danica ^a   Tkáč, Ján ^a   Švitel, Juraj ^b   Pätoprstý, Vladimír ^a   Hrabárová, Eva ^a   Kogan, Grigorij ^a   Kožár, Tibor ^c  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

^b SLOVAK UNIVERSITY OF TECHNOLOGY   (Slovakia)

^c INSTITUTE OF EXPERIMENTAL PHYSICS   (Slovakia)

Author keywords

Anti carbohydrate antibodies; Biomedical diagnostics; Glycan microarrays; Lectin microarrays; Lectinology; Mass spectrometry; Modelling of glycan protein interactions; Recombinant artificial lectins

Indexed keywords

BIOMOLECULES; CARBOHYDRATES; FORECASTING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; MICROARRAYS; ORGANIC COMPOUNDS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ANTI-CARBOHYDRATE ANTIBODIES; BIOMEDICAL DIAGNOSTICS; GLYCAN MICROARRAYS; LECTIN MICROARRAYS; LECTINOLOGY; MODELLING OF GLYCAN-PROTEIN INTERACTIONS; RECOMBINANT/ARTIFICIAL LECTINS;

BIOASSAY;

ANTIBODY; CARBOHYDRATE; DIAGNOSTIC AGENT; LECTIN; PROTEIN;

ANTIBODY; BIOTECHNOLOGY; CARBOHYDRATE; COST-BENEFIT ANALYSIS; MASS SPECTROMETRY; PHYSIOLOGY; PROTEIN; RECOMBINATION;

CHEMISTRY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MICROARRAY ANALYSIS; REVIEW;

ANTIBODIES; CARBOHYDRATES; LECTINS; MASS SPECTROMETRY; MICROARRAY ANALYSIS; PROTEINS;

EID: 57249097143     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2008.07.003     Document Type: Review

References (153)

1. Accelrys Discovery Studio Visualizer, v1.6. Accelrys Software Inc., San Diego, USA, 2002-2006.
2. Adams E.W., Ratner D.M., Bokesch H.R., McMahon J.B., O'Keefe B.R., and Seeberger P.H. Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol 11 (2004) 875-881
3. Adar R., Streicher H., Rozenblatt S., and Sharon N. Synthesis of soybean agglutinin in bacterial and mammalian cells. Eur J Biochem 249 (1997) 684-689
4. Amano K., Takase M., Ando A., and Nagata Y. Production of functional lectin in Pichia pastoris directed by cloned cDNA from Aleuria aurantia. Biosci Biotechnol Biochem 67 (2003) 2277-2279
5. Amano K., Chiba Y., Kasahara Y., Kato Y., Kaneko M.K., Kuno A., Ito H., Kobayashi K., Hirabayashi J., Jigami Y., and Narimatsu H. Engineering of mucin-type human glycoproteins in yeast cells. Proc Natl Acad Sci U S A. 105 (2008) 3232-3237
6. Ambrosi M., Cameron N.R., and Davis B.G. Lectins: tools for the molecular understanding of the glycocode. Org Biomol Chem 3 (2005) 1593-1608
7. Angeloni S., Ridet J.L., Kusy N., Gao H., Crevoisier F., Guinchard S., et al. Glycoprofiling with micro-arrays of glycoconjugates and lectins. Glycobiology 15 (2005) 31-41
8. Arango R., Rodriguez-Arango E., Adar R., Belenky D., Loontiens F.G., Rozenblatt S., et al. Modification by site-directed mutagenesis of the specificity of Erythrina corallodendron lectin for galactose derivatives with bulky substituents at C-2. FEBS Lett 330 (1993) 133-136
9. Baumgartner P., Raemaekers R.J., Durieux A., Gatehouse A., Davies H., and Taylor M. Large-scale production, purification, and characterisation of recombinant Phaseolus vulgaris phytohemagglutinin E-form expressed in the methylotrophic yeast Pichia pastoris. Protein Expr Purif 26 (2002) 394-405
10. Baumgartner P., Harper K., Raemaekers R.J., Durieux A., Gatehouse A.M., Davies H.V., et al. Large-scale production and purification of recombinant Galanthus nivalis agglutinin (GNA) expressed in the methylotrophic yeast Pichia pastoris. Biotechnol Lett 25 (2003) 1281-1285
11. Bezerra W.M., Carvalho C.P., Moreira Rde A., and Grangeiro T.B. Establishment of a heterologous system for the expression of Canavalia brasiliensis lectin: a model for the study of protein splicing. Genet Mol Res 5 (2006) 216-223
12. Blixt O., Head S., Mondala T., Scanlan C., Huflejt M.E., Alvarez R., et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc Natl Acad Sci U S A 101 (2004) 17033-17038
13. Branco A.T., Bernabe R.B., dos Santos Ferreira B., de Oliveira M.V., Garcia A.B., and de Souza Filho G.A. Expression and purification of the recombinant SALT lectin from rice (Oryza sativa L.). Protein Expr Purif 33 (2004) 34-38
14. Bretthauer R.K., and Castellino F.J. Glycosylation of Pichiapastoris-derived proteins. Biotechnol Appl Biochem 30 Pt 3 (1999) 193-200
15. Carlsson J., Mecklenburg M., Lundstrom I., Danielsson B., and Winquist F. Investigation of sera from various species by using lectin affinity arrays and scanning ellipsometry. Anal Chim Acta 530 (2005) 167-171
16. Caron M., and Sève A.-P. Lectins and pathology (2000), Harwood Academic, Australia
17. Chao Q., Casalongue C., Quinn J.M., and Etzler M.E. Expression and partial characterization of Dolichos biflorus seed lectin in Escherichia coli. Arch Biochem Biophys 313 (1994) 346-350
18. Chen S., LaRoche T., Hamelinck D., Bergsma D., Brenner D., Simeone D., et al. Multiplexed analysis of glycan variation on native proteins captured by antibody microarrays. Nat Methods 4 (2007) 437-444
19. Chen S., Zheng T., Shortreed M.R., Alexander C., and Smith L.M. Analysis of cell surface carbohydrate expression patterns in normal and tumorigenic human breast cell lines using lectin arrays. Anal Chem 79 (2007) 5698-5702
20. Chevolot Y., Bouillon C., Vidal S., Morvan F., Meyer A., Cloarec J.P., et al. DNA-based carbohydrate biochips: a platform for surface glyco-engineering. Angew Chem Int Ed Engl 46 (2007) 2398-2402
21. Culf A.S., Cuperlovic-Culf M., and Ouellette R.J. Carbohydrate microarrays: survey of fabrication techniques. OMICS 10 (2006) 289-310
22. Davis J.J., Tkac J., Laurenson S., and Ko Ferrigno P. Peptide aptamers in label-free protein detection: 1. Characterization of the immobilized scaffold. Anal Chem 79 (2007) 1089-1096
23. de Paz J.L., and Seeberger P.H. Recent advances in carbohydrate microarrays. QSAR Comb Sci 25 (2006) 1027-1032
24. Disney M.D., and Seeberger P.H. Carbohydrate arrays as tools for the glycomics revolution. Drug Discov Today Targets 3 (2004) 151-158
25. Disney M.D., and Seeberger P.H. The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens. Chem Biol 11 (2004) 1701-1707
26. Dotan N., Altstock R.T., Schwarz M., and Dukler A. Anti-glycan antibodies as biomarkers for diagnosis and prognosis. Lupus 15 (2006) 442-450
27. Drake R.R., Schwegler E.E., Malik G., Diaz J., Block T., Mehta A., et al. Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers. Mol Cell Proteomics 5 (2006) 1957-1967
28. Ebe Y., Kuno A., Uchiyama N., Koseki-Kuno S., Yamada M., Sato T., et al. Application of lectin microarray to crude samples: differential glycan profiling of Lec mutants. J Biochem 139 (2006) 323-327
29. Eck J., Langer M., Mockel B., Baur A., Rothe M., Zinke H., et al. Cloning of the mistletoe lectin gene and characterization of the recombinant A-chain. Eur J Biochem 264 (1999) 775-784
30. Eck J., Langer M., Mockel B., Witthohn K., Zinke H., and Lentzen H. Characterization of recombinant and plant-derived mistletoe lectin and their B-chains. Eur J Biochem 265 (1999) 788-797
31. Feizi T., and Chai W. Oligosaccharide microarrays to decipher the glycocode. Nat Rev Mol Cell Biol 5 (2004) 582-588
32. Feizi T., Fazio F., Chai W., and Wong C.H. Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics. Curr Opin Struct Biol 13 (2003) 637-645
33. Ferencik M., Rovensky J., Matha V., and Jensen-Jarolim E. Wörterbuch Allergologie und Immunologie: Fachbegriffe, Personen und klinische Daten von A-Z (2005), Springer, Wien
34. Ferrand Y., Crump M.P., and Davis A.P. A synthetic lectin analog for biomimetic disaccharide recognition. Science 318 (2007) 619-622
35. Fischer E. Einfluss der Konfiguration auf die Wirkung der Enzyme. Ber Dtsch Chem Ges 27 (1894) 2985-2993
36. Fromell K., Andersson M., Elihn K., and Caldwell K.D. Nanoparticle decorated surfaces with potential use in glycosylation analysis. Colloids Surf B Biointerfaces 46 (2005) 84-91
37. Fukui S., Feizi T., Galustian C., Lawson A.M., and Chai W. Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions. Nat Biotechnol 20 (2002) 1011-1017
38. Gabius H.J., Andre S., Kaltner H., and Siebert H.C. The sugar code: functional lectinomics. Biochim Biophys Acta 1572 (2002) 165-177
39. Gabius H.J., Siebert H.C., Andre S., Jimenez-Barbero J., and Rudiger H. Chemical biology of the sugar code. Chembiochem 5 (2004) 741-764
40. Gagneux P., and Varki A. Evolutionary considerations in relating oligosaccharide diversity to biological function. Glycobiology 9 (1999) 747-755
41. Giomarelli B., Schumacher K.M., Taylor T.E., Sowder II R.C., Hartley J.L., McMahon J.B., et al. Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture. Protein Expr Purif 47 (2006) 194-202
42. Good, A., Cooper, D.K.C. and Malvolm, A.J., Methods for attenuating antibody-mediated xenograft rejection in human recipients. 1998, USA Patent 5,767,093.
43. Goodsell D.S., Morris G.M., and Olson A.J. Automated docking of flexible ligands: applications of AutoDock. J Mol Recognit 9 (1996) 1-5
44. Groves P., Canales A., Chavez M.I., Palczewska M., Diaz F., Canada F.J., et al. Applications of NMR spectroscopy to the study of lectin-sugar interactions. In: Nilsson C.L. (Ed). Lectins: Analytical Technologies (2007), Elsevier 51
45. Gustafsson A., Kacskovics I., Breimer M.E., Hammarstrom L., and Holgersson J. Carbohydrate phenotyping of human and animal milk glycoproteins. Glycoconj J 22 (2005) 109-118
46. Hardy B.J. The glycosidic linkage flexibility and time-scale similarity hypotheses. J Mol Struct Theochem 395 (1997) 187-200
47. Holgersson J., Gustafsson A., and Breimer M.E. Characteristics of protein-carbohydrate interactions as a basis for developing novel carbohydrate-based antirejection therapies. Immunol Cell Biol 83 (2005) 694-708
48. Horan N., Yan L., Isobe H., Whitesides G.M., and Kahne D. Nonstatistical binding of a protein to clustered carbohydrates. Proc Natl Acad Sci U S A 96 (1999) 11782-11786
49. Horlacher T., and Seeberger P.H. The utility of carbohydrate microarrays in glycomics. OMICS 10 (2006) 490-498
50. Houliston R.S., Yuki N., Hirama T., Khieu N.H., Brisson J.R., Gilbert M., et al. Recognition characteristics of monoclonal antibodies that are cross-reactive with gangliosides and lipooligosaccharide from Campylobacter jejuni strains associated with Guillain-Barre and Fisher syndromes. Biochemistry 46 (2007) 36-44
51. Houseman B.T., and Mrksich M. Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chem Biol 9 (2002) 443-454
52. Hsu K.L., and Mahal L.K. A lectin microarray approach for the rapid analysis of bacterial glycans. Nat Protoc 1 (2006) 543-549
53. Hsu K.L., Pilobello K.T., and Mahal L.K. Analyzing the dynamic bacterial glycome with a lectin microarray approach. Nat Chem Biol 2 (2006) 153-157
54. Hsu K.-L., Gildersleeve J.C., and Mahal L.K. A simple strategy for the creation of a recombinant lectin microarray. Mol BioSyst 4 (2008) 654-662
55. Irimura, T., Matsumoto, M., Yim, M. and Ono, T., Lectins for Analyzing Sugar Chains and Method of Using the Same. 2007, USA Patent 20070243562.
56. Itoh S., Kawasaki N., Hashii N., Harazono A., Matsuishi Y., Hayakawa T., et al. N-linked oligosaccharide analysis of rat brain Thy-1 by liquid chromatography with graphitized carbon column/ion trap-Fourier transform ion cyclotron resonance mass spectrometry in positive and negative ion modes. J Chromatogr A 1103 (2006) 296-306
57. Jiang H., Desaire H., Butnev V.Y., and Bousfield G.R. Glycoprotein profiling by electrospray mass spectrometry. J Am Soc Mass Spectrom 15 (2004) 750-758
58. Kakiuchi M., Okino N., Sueyoshi N., Ichinose S., Omori A., Kawabata S., et al. Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera. Glycobiology 12 (2002) 85-94
59. Karamanska R., Clarke J., Blixt O., Macrae J.I., Zhang J.Q., Crocker P.R., et al. Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays. Glycoconj J 25 (2008) 69-74
60. Kelly, L, Puett, JD, Pierce, JM. Method for cleaving and deglycosylating antibodies to promote ligand binding. 2007, USA Patent, 20070117170.
61. Kirkeby S. A monoclonal anticarbohydrate antibody detecting superfast myosin in the masseter muscle. Cell Tissue Res 283 (1996) 85-92
62. Kirkeby S., Andre S., and Gabius H.J. Solid phase measurements of antibody and lectin binding to xenogenic carbohydrate antigens. Clin Biochem 37 (2004) 36-41
63. Koshi Y., Nakata E., Yamane H., and Hamachi I. A fluorescent lectin array using supramolecular hydrogel for simple detection and pattern profiling for various glycoconjugates. J Am Chem Soc 128 (2006) 10413-10422
64. Kozarova A., Petrinac S., Ali A., and Hudson J.W. Array of informatics: applications in modern research. J Proteome Res 5 (2006) 1051-1059
65. Krengel U., and Imberty A. X-ray crystallography and lectin structure databases. In: Nilsson C.L. (Ed). Lectins: Analytical Technologies (2007), Elsevier 15-50
66. Kuno A., Uchiyama N., Koseki-Kuno S., Ebe Y., Takashima S., Yamada M., et al. Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling. Nat Methods 2 (2005) 851-856
67. Lannoo N., Vervecken W., Proost P., Rouge P., and Van Damme E.J. Expression of the nucleocytoplasmic tobacco lectin in the yeast Pichia pastoris. Protein Expr Purif 53 (2007) 275-282
68. Lee M.R., Park S., and Shin I. Protein microarrays to study carbohydrate-recognition events. Bioorg Med Chem Lett 16 (2006) 5132-5135
69. Lentzen, H., Eck, J., Baur, A. and Zinke, H., Recombinant mistletoe lectin (rML). 2001, USA Patent 6,271,368, 08/776,059.
70. Lin J., Yao J., Zhou X., Sun X., and Tang K. Expression and purification of a novel mannose-binding lectin from Pinellia ternata. Mol Biotechnol 25 (2003) 215-222
71. Love, K.R. and Seeberger, P.H., Carbohydrate arrays as tools for glycomics. Angew Chem Int Ed Engl. 2002; 41:3583-6, 13.
72. MacBeath G., and Schreiber S.L. Printing proteins as microarrays for high-throughput function determination. Science 289 (2000) 1760-1763
73. Mammen M., Choi S.K., and Whitesides G.M. Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew Chem Int Ed Engl 37 (1998) 2755-2794
74. Matsuda A., Kuno A., Ishida H., Kawamoto T., Shoda J.I., and Hirabayashi J. Development of an all-in-one technology for glycan profiling targeting formalin-embedded tissue sections. Biochem Biophys Res Commun. 370 (2008) 259-263
75. Matthiesen, F., Isolation of lectins. 2006, USA Patent 7,049,414.
76. Mecklenburg M., Svitel J., Winquist F., Gang J., Ornstein K., Dey E., et al. Differentiation of human serum samples by surface plasmon resonance monitoring of the integral glycoprotein interaction with a lectin panel. Anal Chim Acta 459 (2002) 25-31
77. Mellet C.O., and Fernandez J.M.G. Carbohydrate microarrays. Chembiochem 3 (2002) [819-+]
78. Melton L. Protein arrays: proteomics in multiplex. Nature 429 (2004) 101-107
79. Menéndez C., Hernández L., País J.M., Banguela A., Ramírez R., Trujillo L.E., et al. Identification and recombinant expression of a bacterial exolevanase useful for the production of high fructose syrups. Biotecnol Apl 22 (2005) 68-72
80. Mislovicova D, Gemeiner P, Kozarova A, Kozar T. Lectinomics I. Relevance of exogenous plant lectins in biomedical diagnostics. Biologia. Submitted for publication.
81. Mitchell S.W. Researches upon the venom of the rattlesnake: with an investigation of the anatomy and physiology of the organs concerned. Smithsonian Contributions to Knowledge (1860) 145
82. Mosedale D.E., Chauhan A., Schofield P.M., and Grainger D.J. A pattern of anti-carbohydrate antibody responses present in patients with advanced atherosclerosis. J Immunol Methods 309 (2006) 182-191
83. Muller-Loennies S., MacKenzie C.R., Patenaude S.I., Evans S.V., Kosma P., Brade H., et al. Characterization of high affinity monoclonal antibodies specific for chlamydial lipopolysaccharide. Glycobiology 10 (2000) 121-130
84. Mullican, M., (2007a) CAS Search Service Report # 1971632 for Lectins used as Diagnostics, Columbus, OH, USA.
85. Mullican, M., (2007b) CAS Search Service Report # 1982214 for Carbohydrate Antibodies used as Diagnostics, Columbus, OH, USA.
86. Nagahora H., Ishikawa K., Niwa Y., Muraki M., and Jigami Y. Expression and secretion of wheat germ agglutinin by Saccharomyces cerevisiae. Eur J Biochem 210 (1992) 989-997
87. Neumann D., Kohlbacher O., Lenhof H.P., and Lehr C.M. Lectin-sugar interaction. Calculated versus experimental binding energies. Eur J Biochem 269 (2002) 1518-1524
88. Neumann D., Lehr C.M., Lenhof H.P., and Kohlbacher O. Computational modeling of the sugar-lectin interaction. Adv Drug Deliv Rev 56 (2004) 437-457
89. Nilsson C. Lectins: Analytical Technologies (2007), Elsevier, Tallahassee, USA
90. Nimrichter L., Gargir A., Gortler M., Altstock R.T., Shtevi A., Weisshaus O., et al. Intact cell adhesion to glycan microarrays. Glycobiology 14 (2004) 197-203
91. Park S., and Shin I. Fabrication of carbohydrate chips for studying protein-carbohydrate interactions. Angew Chem Int Ed Engl 41 (2002) 3180-3182
92. Patwa T.H., Zhao J., Anderson M.A., Simeone D.M., and Lubman D.M. Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multi-lectin fluorescence detection. Anal Chem 78 (2006) 6411-6421
93. Paulson J.C., Blixt O., and Collins B.E. Sweet spots in functional glycomics. Nat Chem Biol 2 (2006) 238-248
94. Pazur J.H. Anti-carbohydrate antibodies with specificity for monosaccharide and oligosaccharide units of antigens. Adv Carbohydr Chem Biochem 53 (1998) 201-261
95. Pazur J.H., and Li N.Q. Application of antibodies for the identification of polysaccharide gum additives in processed foods. Food Addit Contam 21 (2004) 1027-1034
96. Pazur J.H., Reed A.S., and Scrano R.S. Antibodies with specificities for d-xylose and for d-galacturonic acid residues of flaxseed polysaccharides. Carbohydr Res 336 (2001) 195-201
97. Peterman S.M., and Mulholland J.J. A novel approach for identification and characterization of glycoproteins using a hybrid linear ion trap/FT-ICR mass spectrometer. J Am Soc Mass Spectrom 17 (2006) 168-179
98. Petricoin E.F., Belluco C., Araujo R.P., and Liotta L.A. The blood peptidome: a higher dimension of information content for cancer biomarker discovery. Nat Rev Mol Cell Biol 6 (2006) 961-967
99. Piatak MJ. Recombinant lectins. 1998, USAPatent 5,840,522.
100. Pilobello K.T., and Mahal L.K. Deciphering the glycocode: the complexity and analytical challenge of glycomics. Curr Opin Chem Biol 11 (2007) 300-305
101. Pilobello K.T., Krishnamoorthy L., Slawek D., and Mahal L.K. Development of a lectin microarray for the rapid analysis of protein glycopatterns. Chembiochem 6 (2005) 985-989
102. Pilobello K.T., Slawek D.E., and Mahal L.K. A ratiometric lectin microarray approach to analysis of the dynamic mammalian glycome. Proc Natl Acad Sci U S A 104 (2007) 11534-11539
103. Prasthofer T., Phillips S.R., Suddath F.L., and Engler J.A. Design, expression, and crystallization of recombinant lectin from the garden pea (Pisum sativum). J Biol Chem 264 (1989) 6793-6796
104. Raemaekers R.J., de Muro L., Gatehouse J.A., and Fordham-Skelton A.P. Functional phytohemagglutinin (PHA) and Galanthus nivalis agglutinin (GNA) expressed in Pichia pastoris correct N-terminal processing and secretion of heterologous proteins expressed using the PHA-E signal peptide. Eur J Biochem 265 (1999) 394-403
105. Raman R., Raguram S., Venkataraman G., Paulson J.C., and Sasisekharan R. Glycomics: an integrated systems approach to structure-function relationships of glycans. Nat Methods 2 (2005) 817-824
106. Ratner D.M., Adams E.W., Su J., O'Keefe B.R., Mrksich M., and Seeberger P.H. Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides. Chembiochem 5 (2004) 379-382
107. Reuter G., and Gabius H.J. Eukaryotic glycosylation: whim of nature or multipurpose tool?. Cell Mol Life Sci 55 (1999) 368-422
108. Rosenfeld R., Bangio H., Gerwig G.J., Rosenberg R., Aloni R., Cohen Y., et al. A lectin array-based methodology for the analysis of protein glycosylation. J Biochem Biophys Methods 70 (2007) 415-426
109. Sahab Z.J., Semaan S.M., and Sang Q.A. Methodology and applications of disease biomarker identification in human serum. Biomark Insights 2 (2007) 21-43
110. Schena M., Shalon D., Davis R.W., and Brown P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270 (1995) 467-470
111. Seeberger P.H., and Werz D.B. Synthesis and medical applications of oligosaccharides. Nature 446 (2007) 1046-1051
112. Sharma V., and Surolia A. Cloning by genomic PCR and production of peanut agglutinin in Escherichia coli. Gene 148 (1994) 299-304
113. Sharon N. Lectins: carbohydrate-specific reagents and biological recognition molecules. J Biol Chem 282 (2007) 2753-2764
114. Sharon N., and Lis H. Lectins (2003), Kluwer Academic Publishers, Dordrecht
115. Sharon N., and Lis H. History of lectins: from hemagglutinins to biological recognition molecules. Glycobiology 14 (2004) 53R-62R
116. Smith E.A., Thomas W.D., Kiessling L.L., and Corn R.M. Surface plasmon resonance imaging studies of protein-carbohydrate interactions. J Am Chem Soc 125 (2003) 6140-6148
117. Sparbier K., Asperger A., Resemann A., Kessler I., Koch S., Wenzel T., et al. Analysis of glycoproteins in human serum by means of glycospecific magnetic bead separation and LC-MALDI-TOF/TOF analysis with automated glycopeptide detection. J Biomol Tech 18 (2007) 252-258
118. Stancombe P.R., Alexander F.C., Ling R., Matheson M.A., Shone C.C., and Chaddock J.A. Isolation of the gene and large-scale expression and purification of recombinant Erythrina cristagalli lectin. Protein Expr Purif 30 (2003) 283-292
119. Stevens J., Blixt O., Paulson J.C., and Wilson I.A. Glycan microarray technologies: tools to survey host specificity of influenza viruses. Nat Rev Mol Cell Biol 4 (2006) 857-864
120. Stevens J., Blixt O., Tumpey T.M., Taubenberger J.K., Paulson J.C., and Wilson I.A. Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science 312 (2006) 404-410
121. Stillmark H. Uber rizin, ein giftiges ferment aus Samen von Ricinis communis L., und ainigen anderen Euphorbiaceen. Dorpat (Tartu) (1888)
122. Stoltenburg R., Reinemann C., and Strehlitz B. SELEX-a (r)evolutionary method to generate high-affinity nucleic acid ligands. Biomol Eng 24 (2007) 381-403
123. Streicher H., and Sharon N. Recombinant plant lectins and their mutants. Methods Enzymol 363 (2003) 47-77
124. Stubbs M.E., Carver J.P., and Dunn R.J. Production of pea lectin in Escherichia coli. J Biol Chem 261 (1986) 6141-6144
125. Studier F.W., Rosenberg A.H., Dunn J.J., and Dubendorff J.W. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol 185 (1990) 60-89
126. Summerfield J.A. Clinical potential of mannose-binding lectin-replacement therapy. Biochem Soc Trans 31 (2003) 770-773
127. Summit Glycoresearch. Native and Artificial Lectin. http://www.sumitomocorp.co.jp/english/news/2006/20060928_091912.html. 2006.
128. Tamborrini M., Werz D.B., Frey J., Pluschke G., and Seeberger P.H. Anti-carbohydrate antibodies for the detection of anthrax spores. Angew Chem Int Ed Engl 45 (2006) 6581-6582
129. Tateno H., Winter H.C., and Goldstein I.J. Cloning, expression in Escherichia coli and characterization of the recombinant Neu5Acalpha2,6Galbeta1,4GlcNAc-specific high-affinity lectin and its mutants from the mushroom Polyporus squamosus. Biochem J 382 (2004) 667-675
130. Tateno H., Uchiyama N., Kuno A., Togayachi A., Sato T., Narimatsu H., et al. A novel strategy for mammalian cell surface glycome profiling using lectin microarray. Glycobiology 17 (2007) 1138-1146
131. Thiel S, Jensenius JC, Jensen TV. Recombinant human mannan-binding lectin. 2004, USA Patent 0,229,212.
132. Thiel, S., Jensenius, J.C. and Jensen, T.V., Recombinant human mannan-binding lectin. 2005, USA Patent 6,846,649.
133. Tolia N.H., Enemark E.J., Sim B.K., and Joshua-Tor L. Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell 122 (2005) 183-193
134. Turnbull J.E., and Field R.A. Emerging glycomics technologies. Nat Chem Biol 3 (2007) 74-77
135. Uchiyama N., Kuno A., Koseki-Kuno S., Ebe Y., Horio K., Yamada M., et al. Development of a lectin microarray based on an evanescent-field fluorescence principle. Methods Enzymol 415 (2006) 341-351
136. van Kasteren S.I., Kramer H.B., Gamblin D.P., and Davis B.G. Site-selective glycosylation of proteins: creating synthetic glycoproteins. Nat Protoc 2 (2007) 3185-3194
137. Vas V., Fajka-Boja R., Ion G., Dudics V., Monostori E., and Uher F. Biphasic effect of recombinant galectin-1 on the growth and death of early hematopoietic cells. Stem Cells 23 (2005) 279-287
138. Wada Y., Azadi P., Costello C.E., Dell A., Dwek R.A., Geyer H., et al. Comparison of the methods for profiling glycoprotein glycans-HUPO human disease glycomics/proteome initiative multi-institutional study. Glycobiology 17 (2007) 411-422
139. Wakamiya, N., Recombinant conglutinin and producing method thereof. 2000, Patent 6,110,708, 09/011,735.
140. Wallace A.C., Laskowski R.A., and Thornton J.M. LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng 8 (1995) 127-134
141. Wang D., Liu S., Trummer B.J., Deng C., and Wang A. Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells. Nat Biotechnol 20 (2002) 275-281
142. Wearne K.A., Winter H.C., O'Shea K., and Goldstein I.J. Use of lectins for probing differentiated human embryonic stem cells for carbohydrates. Glycobiology 16 (2006) 981-990
143. Weintraub A. Immunology of bacterial polysaccharide antigens. Carbohydr Res 338 (2003) 2539-2547
144. Willats W.G., Limberg G., Buchholt H.C., van Alebeek G.J., Benen J., Christensen T.M., et al. Analysis of pectic epitopes recognised by hybridoma and phage display monoclonal antibodies using defined oligosaccharides, polysaccharides, and enzymatic degradation. Carbohydr Res 327 (2000) 309-320
145. Wright C.S., and Jaeger J. Crystallographic refinement and structure analysis of the complex of wheat germ agglutinin with a bivalent sialoglycopeptide from glycophorin A. J Mol Biol 232 (1993) 620-638
146. Wright M.E., Han D.K., and Aebersold R. Mass spectrometry-based expression profiling of clinical prostate cancer. Mol Cell Proteomics 4 (2005) 545-554
147. Wu A., Buhler L.H., and Cooper D.K. ABO-incompatible organ and bone marrow transplantation: current status. Transpl Int 16 (2003) 291-299
148. Xie K., Song S.C., Spitalnik S.L., and Wedekind J.E. Crystallographic analysis of the NNA7 Fab and proposal for the mode of human blood-group recognition. Acta Crystallogr D Biol Crystallogr 61 (2005) 1386-1394
149. Yabe R., Suzuki R., Kuno A., Fujimoto Z., Jigami Y., and Hirabayashi J. Tailoring a novel sialic acid-binding lectin from a ricin-B chain-like galactose-binding protein by natural evolution-mimicry. J Biochem 141 (2007) 389-399
150. Yim M., Ono T., and Irimura T. Mutated plant lectin library useful to identify different cells. Proc Natl Acad Sci U S A 98 (2001) 2222-2225
151. Zhang X., Li L., Wei D., Yap Y., and Chen F. Moving cancer diagnostics from bench to bedside. Trends Biotechnol 25 (2007) 166-173
152. Zhao J., Patwa T.H., Qiu W., Shedden K., Hinderer R., Misek D.E., et al. Glycoprotein microarrays with multi-lectin detection: unique lectin binding patterns as a tool for classifying normal, chronic pancreatitis and pancreatic cancer sera. J Proteome Res 6 (2007) 1864-1874
153. Zheng T., Peelen D., and Smith L.M. Lectin arrays for profiling cell surface carbohydrate expression. J Am Chem Soc 127 (2005) 9982-9983