Carbohydrate arrays as tools for the glycomics revolution

Drug Discovery Today: TARGETS

Volumn 3, Issue 4, 2004, Pages 151-158

  Disney, Matthew D ^a   Seeberger, Peter H ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Carbohydrate arrays; Chemical Biology; Drug Discovery; Glycobiology; Glycomics; High throughput screening; Pharmaceutical Science

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBODY; ANTIBODY 2G12; CYANOVIRIN N; GLASS; GLYCOSYLTRANSFERASE INHIBITOR; GOLD; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MICROSPHERE; PYROXYLIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CYTOLOGY; GLYCOBIOLOGY; HIGH THROUGHPUT SCREENING; MICROTITER PLATE ASSAY; REVIEW; SURFACE PLASMON RESONANCE;

EID: 12344263742     PISSN: 17418372     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1741-8372(04)02443-0     Document Type: Review

References (45)

1. Brown P.O., Botstein D. Exploring the new world of the genome with DNA microarrays. Nat. Genet. 21:1999;33-37
2. Sanger F. Determination of nucleotide sequences in DNA. Science. 214:1981;1205-1210
3. Caruthers M.H. Gene synthesis machines: DNA chemistry and its uses. Science. 230:1985;281-285
4. Caruthers M.H., et al. Chemical synthesis of deoxyoligonucleotides by the phosphoramidite method. Methods Enzymol. 154:1987;287-313
5. Mullis K.B. The polymerase chain reaction in an anemic mode: how to avoid cold oligodeoxyribonuclear fusion. PCR Methods Appl. 1:1991;1-4
6. Berg P. Dissections and reconstructions of genes and chromosomes. Science. 213:1981;296-303
7. Wuthrich K. The second decade-into the third millennium. Nat. Struct. Biol. 5:1998;492-495
8. Kohn W. Density-functional theory for systems of very many atoms. Int. J. Quantum Chem. 56:1995;229-232
9. Windus T.L., Pople J.A. Pinnacle - an approach toward object-oriented quantum-chemistry. Int. J. Quantum Chem. 29:1995;485-495
10. Karlsson K.A. Bacterium-host protein-carbohydrate interactions and pathogenicity. Biochem. Soc. Trans. 27:1999;471-474
11. Sacchettini J.C., et al. Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction. Biochemistry. 40:2001;3009-3015
12. Kansas G.S. Selectins and their ligands: current concepts and controversies. Blood. 88:1996;3259-3287
13. Vacquier V.D., Moy G.W. The fucose sulfate polymer of egg jelly binds to sperm REJ and is the inducer of the sea urchin sperm acrosome reaction. Dev. Biol. 192:1997;125-135
14. Fugedi P. The potential of the molecular diversity of heparin and heparan sulfate for drug development. Mini Rev. Med. Chem. 3:2003;659-667
15. Vicens Q., Westhof E. Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: an analysis of X-ray crystal structures. Biopolymers. 70:2003;42-57
16. Schofield L., et al. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature. 418:2002;785-789
17. Plante O.J., et al. Automated solid-phase synthesis of oligosaccharides. Science. 291:2001;1523-1527
18. Wacker M., et al. N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science. 298:2002;1790-1793
19. Sears P., Wong C.H. Toward automated synthesis of oligosaccharides and glycoproteins. Science. 291:2001;2344-2350
20. Kiessling L.L., et al. Synthetic multivalent ligands in the exploration of cell-surface interactions. Curr. Opin. Chem. Biol. 4:2000;696-703
21. Wang D., et al. Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells. Nat. Biotechnol. 20:2002;275-281
22. Fukui S., et al. Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions. Nat. Biotechnol. 20:2002;1011-1017
23. Feizi T., et al. Neoglycolipids: probes of oligosaccharide structure, antigenicity, and function. Methods Enzymol. 230:1994;484-519
24. Bryan M.C., et al. Saccharide display on microtiter plates. Chem. Biol. 9:2002;713-720
25. Wong C.H., Bryan M.C. Sugar arrays in microtiter plates. Methods Enzymol. 362:2003;218-225
26. Fazio F., et al. Synthesis of sugar arrays in microtiter plate. J. Am. Chem. Soc. 124:2002;14397-14402
27. Kuruvilla F.G., et al. Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays. Nature. 416:2002;653-657
28. Hergenrother P.J., et al. Small-molecule microarrays: covalent attachment and screening of alcohol-containing small molecules on glass slides. J. Am. Chem. Soc. 122:2000;7849-7850
29. MacBeath G., et al. Printing small molecules as microarrays and detecting protein-ligand interactions en masse. J. Am. Chem. Soc. 121:1999;7967-7968
30. Houseman B.T., Mrksich M. Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chem. Biol. 9:2002;443-454
31. Park S., Shin I. Fabrication of carbohydrate chips for studying protein-carbohydrate interactions. Angew. Chem. Int. Ed. Engl. 41:2002;3180-3182
32. Adams E.W., et al. Encoded fiber-optic microsphere arrays for probing protein-carbohydrate interactions. Angew. Chem. Int. Ed. Engl. 42:2003;5317-5320
33. Ratner D.M., et al. Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides. Chembiochem. 5:2004;379-382
34. Pierson T.C., Doms R.W. HIV-1 entry inhibitors: new targets, novel therapies. Immunol. Lett. 85:2003;113-118
35. Lin G., et al. Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR. J. Virol. 77:2003;1337-1346
36. Delmas B., Laude H. Assembly of coronavirus spike protein into trimers and its role in epitope expression. J. Virol. 64:1990;5367-5375
37. Shenoy S.R., et al. Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization. Chem. Biol. 9:2002;1109-1118
38. Tsai C.C., et al. Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res. Hum. Retroviruses. 20:2004;11-18
39. Tziveleka L.A., et al. Natural products with anti-HIV activity from marine organisms. Curr. Top. Med. Chem. 3:2003;1512-1535
40. Smith E.A., et al. Surface plasmon resonance imaging studies of protein-carbohydrate interactions. J. Am. Chem. Soc. 125:2003;6140-6148
41. Disney M.D., et al. Aminoglycoside microarrays to study antibiotic resistance. Angew. Chem. Int. Ed. Engl. 43:2004;1591-1594
42. Disney M.D., Seeberger P.H. Aminoglycoside microarrays to explore interactions of antibiotics to RNAs and proteins. Chemistry - A European Journal. 10:2004;3308-3314
43. Trikola A., et al. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 of human immunodeficiency virus type 2. J. Virol. 70:1996;1100-1108
44. Stiegler G., et al. Antiviral activity of the neutralizing antibodies 2F5 and 2G12 in asymptomatic HIV-1 infected human: a phase 1 clinical trial. AIDS. 16:2002;2019-2025
45. Adams E.W., et al. Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem. Biol. 11:2004;875-881