Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734

Cancer Research

Volumn 68, Issue 23, 2008, Pages 9779-9787

  Herrero, Ana B ^a   Astudillo, Alma M ^b   Balboa, María A ^b   Cuevas, Carmen ^c   Balsinde, Jesús ^b   Moreno, Sergio ^a  

^a Salamanca Spain   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c PHARMAMAR S A   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CERAMIDE; CYTOTOXIC AGENT; FATTY ACID; FATTY ACYL 2 HYDROXYLASE; KAHALALIDE F; OXYGENASE; PALMITIC ACID; PM 02734; SMALL INTERFERING RNA; SPHINGOLIPID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; DELETION MUTANT; DRUG SENSITIVITY; FA2H GENE; GENE; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HYDROXYLATION; MAMMAL CELL; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SCS7 GENE; VALIDATION PROCESS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL GROWTH PROCESSES; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; DEPSIPEPTIDES; FATTY ACIDS; GENE DELETION; HCT116 CELLS; HELA CELLS; HUMANS; HYDROXYLATION; MIXED FUNCTION OXYGENASES; RNA, MESSENGER; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFECTION;

EID: 57149103130     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1981     Document Type: Article

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