Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

Journal of Clinical Investigation

Volumn 100, Issue 11, 1997, Pages 2849-2857

  Jin, Xiaowei ^a   Shepherd, Rebecca K ^a   Duling, Brian R ^a   Linden, Joel ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Asthma; Purinergic; Receptors; Vasoconstriction; Xanthines

Indexed keywords

ADENOSINE A3 RECEPTOR; INOSINE DERIVATIVE; 3 IODO N(6) 4 AMINOBENZYLADENOSINE; 3-IODO-N(6)-4-AMINOBENZYLADENOSINE; 6 N (5 HYDROXYNORBORNAN 2 YL) 8 (N ISOPROPYL N METHYLAMINO) 9 METHYLADENINE; ADENINE; ADENOSINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; HYBRID PROTEIN; INOSINE; IODOBENZENE; NORBORNANE DERIVATIVE; RADIOACTIVE IODINE;

ANIMAL CELL; ARTICLE; CHEEK POUCH; DEAMINATION; DRUG RECEPTOR BINDING; FACILITATION; GENETIC RECOMBINATION; HISTAMINE RELEASE; MAST CELL DEGRANULATION; NONHUMAN; PRIORITY JOURNAL; TISSUE CULTURE; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; ANIMAL; ARTERIOLE; BINDING COMPETITION; CELL CULTURE; DEGRANULATION; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; GUINEA PIG; HAMSTER; LUNG; MAST CELL; METABOLISM; PHYSIOLOGY; RAT;

ADENINE; ADENOSINE; ANIMALS; ARTERIOLES; BINDING, COMPETITIVE; CELL DEGRANULATION; CRICETINAE; GUINEA PIGS; INOSINE; IODINE RADIOISOTOPES; IODOBENZENES; LUNG; MAST CELLS; NORBORNANES; RATS; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0031283479     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119833     Document Type: Article

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