메뉴 건너뛰기




Volumn 77, Issue 1, 2009, Pages 54-65

Glycogen synthase kinase-3 inhibitors augment TRAIL-induced apoptotic death in human hepatoma cells

Author keywords

Apoptosis; c Jun N terminal kinase; CD95; Hepatocellular carcinoma; Lithium; SB 415286

Indexed keywords

(1,3 BENZOTHIAZOL 2 YL)[2 [2 (3 PYRIDINYL)ETHYLAMINO] 4 PYRIMIDINYL]ACETONITRILE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CAMPTOTHECIN; CASPASE 3; FAS ANTIGEN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; LITHIUM; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 57049124808     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.09.026     Document Type: Article
Times cited : (41)

References (69)
  • 2
    • 33745547361 scopus 로고    scopus 로고
    • New therapies for hepatocellular carcinoma
    • Avila M.A., Berasain C., Sangro B., and Prieto J. New therapies for hepatocellular carcinoma. Oncogene 25 (2006) 3866-3884
    • (2006) Oncogene , vol.25 , pp. 3866-3884
    • Avila, M.A.1    Berasain, C.2    Sangro, B.3    Prieto, J.4
  • 3
    • 21044445452 scopus 로고    scopus 로고
    • Apoptosis: a mechanism of acute and chronic liver injury
    • Guicciardi M.E., and Gores G.J. Apoptosis: a mechanism of acute and chronic liver injury. Gut 54 (2005) 1024-1033
    • (2005) Gut , vol.54 , pp. 1024-1033
    • Guicciardi, M.E.1    Gores, G.J.2
  • 4
    • 14744304730 scopus 로고    scopus 로고
    • Modulation of apoptosis as a target for liver disease
    • Eichhorst S.T. Modulation of apoptosis as a target for liver disease. Expert Opin Ther Targets 9 (2005) 83-99
    • (2005) Expert Opin Ther Targets , vol.9 , pp. 83-99
    • Eichhorst, S.T.1
  • 5
    • 0030035921 scopus 로고    scopus 로고
    • Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues
    • Higaki K., Yano H., and Kojiro M. Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues. Am J Pathol 149 (1996) 429-437
    • (1996) Am J Pathol , vol.149 , pp. 429-437
    • Higaki, K.1    Yano, H.2    Kojiro, M.3
  • 6
    • 0034098493 scopus 로고    scopus 로고
    • The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma
    • Ito Y., Monden M., Takeda T., Eguchi H., Umeshita K., Nagano H., et al. The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma. Br J Cancer 82 (2000) 1211-1217
    • (2000) Br J Cancer , vol.82 , pp. 1211-1217
    • Ito, Y.1    Monden, M.2    Takeda, T.3    Eguchi, H.4    Umeshita, K.5    Nagano, H.6
  • 7
    • 16144363507 scopus 로고    scopus 로고
    • Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?
    • Strand S., Hofmann W.J., Hug H., Muller M., Otto G., Strand D., et al. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?. Nat Med 2 (1996) 1361-1366
    • (1996) Nat Med , vol.2 , pp. 1361-1366
    • Strand, S.1    Hofmann, W.J.2    Hug, H.3    Muller, M.4    Otto, G.5    Strand, D.6
  • 8
    • 0036895749 scopus 로고    scopus 로고
    • TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells
    • Kim Y.S., Schwabe R.F., Qian T., Lemasters J.J., and Brenner D.A. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36 (2002) 1498-1508
    • (2002) Hepatology , vol.36 , pp. 1498-1508
    • Kim, Y.S.1    Schwabe, R.F.2    Qian, T.3    Lemasters, J.J.4    Brenner, D.A.5
  • 9
    • 0033839749 scopus 로고    scopus 로고
    • Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
    • Yamanaka T., Shiraki K., Sugimoto K., Ito T., Fujikawa K., Ito M., et al. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 32 (2000) 482-490
    • (2000) Hepatology , vol.32 , pp. 482-490
    • Yamanaka, T.1    Shiraki, K.2    Sugimoto, K.3    Ito, T.4    Fujikawa, K.5    Ito, M.6
  • 10
    • 0037204818 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
    • Shin E.C., Seong Y.R., Kim C.H., Kim H., Ahn Y.S., Kim K., et al. Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Exp Mol Med 34 (2002) 114-122
    • (2002) Exp Mol Med , vol.34 , pp. 114-122
    • Shin, E.C.1    Seong, Y.R.2    Kim, C.H.3    Kim, H.4    Ahn, Y.S.5    Kim, K.6
  • 11
    • 4344607589 scopus 로고    scopus 로고
    • Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
    • Ganten T.M., Haas T.L., Sykora J., Stahl H., Sprick M.R., Fas S.C., et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ 11 Suppl. 1 (2004) S86-S96
    • (2004) Cell Death Differ , vol.11 SUPPL. 1
    • Ganten, T.M.1    Haas, T.L.2    Sykora, J.3    Stahl, H.4    Sprick, M.R.5    Fas, S.C.6
  • 12
    • 0042809497 scopus 로고    scopus 로고
    • Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma
    • Okano H., Shiraki K., Inoue H., Kawakita T., Yamanaka T., Deguchi M., et al. Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma. Lab Invest 83 (2003) 1033-1043
    • (2003) Lab Invest , vol.83 , pp. 1033-1043
    • Okano, H.1    Shiraki, K.2    Inoue, H.3    Kawakita, T.4    Yamanaka, T.5    Deguchi, M.6
  • 14
    • 17544373837 scopus 로고    scopus 로고
    • Survivin promotes cell proliferation in human hepatocellular carcinoma
    • Ito T., Shiraki K., Sugimoto K., Yamanaka T., Fujikawa K., Ito M., et al. Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology 31 (2000) 1080-1085
    • (2000) Hepatology , vol.31 , pp. 1080-1085
    • Ito, T.1    Shiraki, K.2    Sugimoto, K.3    Yamanaka, T.4    Fujikawa, K.5    Ito, M.6
  • 15
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., and Woodgett J.R. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406 (2000) 86-90
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 16
    • 0036081578 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes
    • Schwabe R.F., and Brenner D.A. Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes. Am J Physiol Gastrointest Liver Physiol 283 (2002) G204-G211
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Schwabe, R.F.1    Brenner, D.A.2
  • 17
    • 2642523803 scopus 로고    scopus 로고
    • Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor
    • Song L., Zhou T., and Jope R.S. Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor. BMC Neurosci 5 (2004) 20
    • (2004) BMC Neurosci , vol.5 , pp. 20
    • Song, L.1    Zhou, T.2    Jope, R.S.3
  • 18
    • 2542425324 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer
    • Liao X., Zhang L., Thrasher J.B., Du J., and Li B. Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer. Mol Cancer Ther 2 (2003) 1215-1222
    • (2003) Mol Cancer Ther , vol.2 , pp. 1215-1222
    • Liao, X.1    Zhang, L.2    Thrasher, J.B.3    Du, J.4    Li, B.5
  • 19
    • 27244444199 scopus 로고    scopus 로고
    • A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function
    • Rottmann S., Wang Y., Nasoff M., Deveraux Q.L., and Quon K.C. A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function. Proc Natl Acad Sci U S A 102 (2005) 15195-15200
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15195-15200
    • Rottmann, S.1    Wang, Y.2    Nasoff, M.3    Deveraux, Q.L.4    Quon, K.C.5
  • 20
    • 0032721833 scopus 로고    scopus 로고
    • Phase I and phase II drug-metabolizing enzymes are expressed and heterogeneously distributed in the biliary epithelium
    • Lakehal F., Wendum D., Barbu V., Becquemont L., Poupon R., Balladur P., et al. Phase I and phase II drug-metabolizing enzymes are expressed and heterogeneously distributed in the biliary epithelium. Hepatology 30 (1999) 1498-1506
    • (1999) Hepatology , vol.30 , pp. 1498-1506
    • Lakehal, F.1    Wendum, D.2    Barbu, V.3    Becquemont, L.4    Poupon, R.5    Balladur, P.6
  • 21
    • 0035843148 scopus 로고    scopus 로고
    • Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
    • Desbois-Mouthon C., Cadoret A., Blivet-Van Eggelpoel M.J., Bertrand F., Cherqui G., Perret C., et al. Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 20 (2001) 252-259
    • (2001) Oncogene , vol.20 , pp. 252-259
    • Desbois-Mouthon, C.1    Cadoret, A.2    Blivet-Van Eggelpoel, M.J.3    Bertrand, F.4    Cherqui, G.5    Perret, C.6
  • 22
    • 0037069330 scopus 로고    scopus 로고
    • Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways
    • Martinez L.A., Naguibneva I., Lehrmann H., Vervisch A., Tchenio T., Lozano G., et al. Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. Proc Natl Acad Sci U S A 99 (2002) 14849-14854
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14849-14854
    • Martinez, L.A.1    Naguibneva, I.2    Lehrmann, H.3    Vervisch, A.4    Tchenio, T.5    Lozano, G.6
  • 23
    • 0033588815 scopus 로고    scopus 로고
    • Reciprocal enhancement of gene transfer by combinatorial adenovirus transduction and plasmid DNA transfection in vitro and in vivo
    • Dunphy E.J., Redman R.A., Herweijer H., and Cripe T.P. Reciprocal enhancement of gene transfer by combinatorial adenovirus transduction and plasmid DNA transfection in vitro and in vivo. Hum Gene Ther 10 (1999) 2407-2417
    • (1999) Hum Gene Ther , vol.10 , pp. 2407-2417
    • Dunphy, E.J.1    Redman, R.A.2    Herweijer, H.3    Cripe, T.P.4
  • 24
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 93 (1996) 8455-8459
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 25
    • 0033776383 scopus 로고    scopus 로고
    • Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
    • Coghlan M.P., Culbert A.A., Cross D.A., Corcoran S.L., Yates J.W., Pearce N.J., et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem Biol 7 (2000) 793-803
    • (2000) Chem Biol , vol.7 , pp. 793-803
    • Coghlan, M.P.1    Culbert, A.A.2    Cross, D.A.3    Corcoran, S.L.4    Yates, J.W.5    Pearce, N.J.6
  • 26
    • 0031743648 scopus 로고    scopus 로고
    • p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
    • Muller M., Wilder S., Bannasch D., Israeli D., Lehlbach K., Li-Weber M., et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 188 (1998) 2033-2045
    • (1998) J Exp Med , vol.188 , pp. 2033-2045
    • Muller, M.1    Wilder, S.2    Bannasch, D.3    Israeli, D.4    Lehlbach, K.5    Li-Weber, M.6
  • 27
    • 9244237679 scopus 로고    scopus 로고
    • TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
    • Hao C., Song J.H., Hsi B., Lewis J., Song D.K., Petruk K.C., et al. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res 64 (2004) 8502-8506
    • (2004) Cancer Res , vol.64 , pp. 8502-8506
    • Hao, C.1    Song, J.H.2    Hsi, B.3    Lewis, J.4    Song, D.K.5    Petruk, K.C.6
  • 29
    • 33646393778 scopus 로고    scopus 로고
    • Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
    • Ganten T.M., Koschny R., Sykora J., Schulze-Bergkamen H., Buchler P., Haas T.L., et al. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 12 (2006) 2640-2646
    • (2006) Clin Cancer Res , vol.12 , pp. 2640-2646
    • Ganten, T.M.1    Koschny, R.2    Sykora, J.3    Schulze-Bergkamen, H.4    Buchler, P.5    Haas, T.L.6
  • 31
    • 0037444380 scopus 로고    scopus 로고
    • Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel
    • Asakuma J., Sumitomo M., Asano T., and Hayakawa M. Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel. Cancer Res 63 (2003) 1365-1370
    • (2003) Cancer Res , vol.63 , pp. 1365-1370
    • Asakuma, J.1    Sumitomo, M.2    Asano, T.3    Hayakawa, M.4
  • 32
    • 34047258345 scopus 로고    scopus 로고
    • Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway
    • Pespeni M.H., Hodnett M., Abayasiriwardana K.S., Roux J., Howard M., Broaddus V.C., et al. Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway. Cancer Res 67 (2007) 2865-2871
    • (2007) Cancer Res , vol.67 , pp. 2865-2871
    • Pespeni, M.H.1    Hodnett, M.2    Abayasiriwardana, K.S.3    Roux, J.4    Howard, M.5    Broaddus, V.C.6
  • 33
    • 34848876387 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation
    • Han H., Shin S.W., Seo C.Y., Kwon H.C., Han J.Y., Kim I.H., et al. 15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation. Apoptosis 12 (2007) 2101-2114
    • (2007) Apoptosis , vol.12 , pp. 2101-2114
    • Han, H.1    Shin, S.W.2    Seo, C.Y.3    Kwon, H.C.4    Han, J.Y.5    Kim, I.H.6
  • 34
    • 1942436864 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells
    • He Q., Huang Y., and Sheikh M.S. Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells. Oncogene 23 (2004) 2554-2558
    • (2004) Oncogene , vol.23 , pp. 2554-2558
    • He, Q.1    Huang, Y.2    Sheikh, M.S.3
  • 35
    • 2942565827 scopus 로고    scopus 로고
    • Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications
    • Shankar S., and Srivastava R.K. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist Updat 7 (2004) 139-156
    • (2004) Drug Resist Updat , vol.7 , pp. 139-156
    • Shankar, S.1    Srivastava, R.K.2
  • 36
    • 16644381453 scopus 로고    scopus 로고
    • Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells
    • Inoue H., Shiraki K., Murata K., Sugimoto K., Kawakita T., Yamaguchi Y., et al. Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells. Int J Mol Med 14 (2004) 271-275
    • (2004) Int J Mol Med , vol.14 , pp. 271-275
    • Inoue, H.1    Shiraki, K.2    Murata, K.3    Sugimoto, K.4    Kawakita, T.5    Yamaguchi, Y.6
  • 37
    • 33748291763 scopus 로고    scopus 로고
    • Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway
    • Hu H., Jiang C., Schuster T., Li G.X., Daniel P.T., and Lu J. Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway. Mol Cancer Ther 5 (2006) 1873-1882
    • (2006) Mol Cancer Ther , vol.5 , pp. 1873-1882
    • Hu, H.1    Jiang, C.2    Schuster, T.3    Li, G.X.4    Daniel, P.T.5    Lu, J.6
  • 38
    • 33845349483 scopus 로고    scopus 로고
    • Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment
    • McKee C.M., Ye Y., and Richburg J.H. Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment. Apoptosis 11 (2006) 2237-2250
    • (2006) Apoptosis , vol.11 , pp. 2237-2250
    • McKee, C.M.1    Ye, Y.2    Richburg, J.H.3
  • 39
    • 34249106201 scopus 로고    scopus 로고
    • Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells
    • Secchiero P., Zerbinati C., di Iasio M.G., Melloni E., Tiribelli M., Grill V., et al. Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells. Curr Drug Metab 8 (2007) 395-403
    • (2007) Curr Drug Metab , vol.8 , pp. 395-403
    • Secchiero, P.1    Zerbinati, C.2    di Iasio, M.G.3    Melloni, E.4    Tiribelli, M.5    Grill, V.6
  • 40
    • 27144557493 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta
    • Pluquet O., Qu L.K., Baltzis D., and Koromilas A.E. Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta. Mol Cell Biol 25 (2005) 9392-9405
    • (2005) Mol Cell Biol , vol.25 , pp. 9392-9405
    • Pluquet, O.1    Qu, L.K.2    Baltzis, D.3    Koromilas, A.E.4
  • 41
    • 23344447873 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
    • Kulikov R., Boehme K.A., and Blattner C. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Mol Cell Biol 25 (2005) 7170-7180
    • (2005) Mol Cell Biol , vol.25 , pp. 7170-7180
    • Kulikov, R.1    Boehme, K.A.2    Blattner, C.3
  • 42
    • 0442274617 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
    • Watcharasit P., Bijur G.N., Song L., Zhu J., Chen X., and Jope R.S. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem 278 (2003) 48872-48879
    • (2003) J Biol Chem , vol.278 , pp. 48872-48879
    • Watcharasit, P.1    Bijur, G.N.2    Song, L.3    Zhu, J.4    Chen, X.5    Jope, R.S.6
  • 43
    • 6044240634 scopus 로고    scopus 로고
    • Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
    • Nakshatri H., Rice S.E., and Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23 (2004) 7330-7344
    • (2004) Oncogene , vol.23 , pp. 7330-7344
    • Nakshatri, H.1    Rice, S.E.2    Bhat-Nakshatri, P.3
  • 44
    • 33646271827 scopus 로고    scopus 로고
    • 1-Methoxy-canthin-6-one induces c-Jun NH2-terminal kinase-dependent apoptosis and synergizes with tumor necrosis factor-related apoptosis-inducing ligand activity in human neoplastic cells of hematopoietic or endodermal origin
    • Ammirante M., Di Giacomo R., De Martino L., Rosati A., Festa M., Gentilella A., et al. 1-Methoxy-canthin-6-one induces c-Jun NH2-terminal kinase-dependent apoptosis and synergizes with tumor necrosis factor-related apoptosis-inducing ligand activity in human neoplastic cells of hematopoietic or endodermal origin. Cancer Res 66 (2006) 4385-4393
    • (2006) Cancer Res , vol.66 , pp. 4385-4393
    • Ammirante, M.1    Di Giacomo, R.2    De Martino, L.3    Rosati, A.4    Festa, M.5    Gentilella, A.6
  • 45
    • 0037743569 scopus 로고    scopus 로고
    • Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase
    • Sah N.K., Munshi A., Kurland J.F., McDonnell T.J., Su B., and Meyn R.E. Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase. J Biol Chem 278 (2003) 20593-20602
    • (2003) J Biol Chem , vol.278 , pp. 20593-20602
    • Sah, N.K.1    Munshi, A.2    Kurland, J.F.3    McDonnell, T.J.4    Su, B.5    Meyn, R.E.6
  • 46
    • 0037815359 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells
    • Vivo C., Liu W., and Broaddus V.C. c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells. J Biol Chem 278 (2003) 25461-25467
    • (2003) J Biol Chem , vol.278 , pp. 25461-25467
    • Vivo, C.1    Liu, W.2    Broaddus, V.C.3
  • 47
    • 0037853146 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1)
    • Kim J.W., Lee J.E., Kim M.J., Cho E.G., Cho S.G., and Choi E.J. Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J Biol Chem 278 (2003) 13995-14001
    • (2003) J Biol Chem , vol.278 , pp. 13995-14001
    • Kim, J.W.1    Lee, J.E.2    Kim, M.J.3    Cho, E.G.4    Cho, S.G.5    Choi, E.J.6
  • 48
    • 0032705688 scopus 로고    scopus 로고
    • Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo
    • Yuan P., Chen G., and Manji H.K. Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo. J Neurochem 73 (1999) 2299-2309
    • (1999) J Neurochem , vol.73 , pp. 2299-2309
    • Yuan, P.1    Chen, G.2    Manji, H.K.3
  • 49
    • 10944237268 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase
    • Liu S., Yu S., Hasegawa Y., Lapushin R., Xu H.J., Woodgett J.R., et al. Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. J Biol Chem 279 (2004) 51075-51081
    • (2004) J Biol Chem , vol.279 , pp. 51075-51081
    • Liu, S.1    Yu, S.2    Hasegawa, Y.3    Lapushin, R.4    Xu, H.J.5    Woodgett, J.R.6
  • 50
    • 22244479745 scopus 로고    scopus 로고
    • Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase
    • Gaillard P., Jeanclaude-Etter I., Ardissone V., Arkinstall S., Cambet Y., Camps M., et al. Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase. J Med Chem 48 (2005) 4596-4607
    • (2005) J Med Chem , vol.48 , pp. 4596-4607
    • Gaillard, P.1    Jeanclaude-Etter, I.2    Ardissone, V.3    Arkinstall, S.4    Cambet, Y.5    Camps, M.6
  • 52
    • 33644832724 scopus 로고    scopus 로고
    • Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents
    • Rowinsky E.K. Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents. J Clin Oncol 23 (2005) 9394-9407
    • (2005) J Clin Oncol , vol.23 , pp. 9394-9407
    • Rowinsky, E.K.1
  • 54
    • 42949086433 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of liver injury
    • Malhi H., and Gores G.J. Cellular and molecular mechanisms of liver injury. Gastroenterology 134 (2008) 1641-1654
    • (2008) Gastroenterology , vol.134 , pp. 1641-1654
    • Malhi, H.1    Gores, G.J.2
  • 55
    • 52049094596 scopus 로고    scopus 로고
    • Differential regulation of STAT family members by glycogen synthase kinase-3
    • Beurel E., and Jope R.S. Differential regulation of STAT family members by glycogen synthase kinase-3. J Biol Chem 283 (2008) 21934-21944
    • (2008) J Biol Chem , vol.283 , pp. 21934-21944
    • Beurel, E.1    Jope, R.S.2
  • 56
    • 33947597084 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics
    • Jope R.S., Yuskaitis C.J., and Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 32 (2007) 577-595
    • (2007) Neurochem Res , vol.32 , pp. 577-595
    • Jope, R.S.1    Yuskaitis, C.J.2    Beurel, E.3
  • 57
    • 33750994327 scopus 로고    scopus 로고
    • Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis
    • Inoue S., Twiddy D., Dyer M.J., and Cohen G.M. Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis. Cell Death Differ 13 (2006) 2160-2162
    • (2006) Cell Death Differ , vol.13 , pp. 2160-2162
    • Inoue, S.1    Twiddy, D.2    Dyer, M.J.3    Cohen, G.M.4
  • 58
    • 85047695600 scopus 로고    scopus 로고
    • Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis
    • Kim J.Y., Kim Y.H., Chang I., Kim S., Pak Y.K., Oh B.H., et al. Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis. Oncogene 21 (2002) 3139-3148
    • (2002) Oncogene , vol.21 , pp. 3139-3148
    • Kim, J.Y.1    Kim, Y.H.2    Chang, I.3    Kim, S.4    Pak, Y.K.5    Oh, B.H.6
  • 59
    • 0037910211 scopus 로고    scopus 로고
    • The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death
    • Czaja M.J. The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death. Am J Physiol Gastrointest Liver Physiol 284 (2003) G875-G879
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Czaja, M.J.1
  • 60
    • 0346422479 scopus 로고    scopus 로고
    • Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1
    • Higuchi H., Grambihler A., Canbay A., Bronk S.F., and Gores G.J. Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem 279 (2004) 51-60
    • (2004) J Biol Chem , vol.279 , pp. 51-60
    • Higuchi, H.1    Grambihler, A.2    Canbay, A.3    Bronk, S.F.4    Gores, G.J.5
  • 61
    • 0037308871 scopus 로고    scopus 로고
    • Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells
    • Bae M.A., and Song B.J. Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells. Mol Pharmacol 63 (2003) 401-408
    • (2003) Mol Pharmacol , vol.63 , pp. 401-408
    • Bae, M.A.1    Song, B.J.2
  • 62
    • 33745758229 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity
    • Gunawan B.K., Liu Z.X., Han D., Hanawa N., Gaarde W.A., and Kaplowitz N. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gastroenterology 131 (2006) 165-178
    • (2006) Gastroenterology , vol.131 , pp. 165-178
    • Gunawan, B.K.1    Liu, Z.X.2    Han, D.3    Hanawa, N.4    Gaarde, W.A.5    Kaplowitz, N.6
  • 63
    • 0032979438 scopus 로고    scopus 로고
    • Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
    • Behrens A., Sibilia M., and Wagner E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21 (1999) 326-329
    • (1999) Nat Genet , vol.21 , pp. 326-329
    • Behrens, A.1    Sibilia, M.2    Wagner, E.F.3
  • 64
  • 65
    • 48449090284 scopus 로고    scopus 로고
    • The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX
    • Aderca I., Moser C.D., Veerasamy M., Bani-Hani A.H., Bonilla-Guerrero R., Ahmed K., et al. The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. J Hepatol 49 (2008) 373-383
    • (2008) J Hepatol , vol.49 , pp. 373-383
    • Aderca, I.1    Moser, C.D.2    Veerasamy, M.3    Bani-Hani, A.H.4    Bonilla-Guerrero, R.5    Ahmed, K.6
  • 66
    • 33748299477 scopus 로고    scopus 로고
    • The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
    • Beurel E., and Jope R.S. The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog Neurobiol 79 (2006) 173-189
    • (2006) Prog Neurobiol , vol.79 , pp. 173-189
    • Beurel, E.1    Jope, R.S.2
  • 67
    • 33750866196 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions
    • Jope R.S., and Roh M.S. Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr Drug Targets 7 (2006) 1421-1434
    • (2006) Curr Drug Targets , vol.7 , pp. 1421-1434
    • Jope, R.S.1    Roh, M.S.2
  • 68
    • 33750881942 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes
    • Henriksen E.J., and Dokken B.B. Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes. Curr Drug Targets 7 (2006) 1435-1441
    • (2006) Curr Drug Targets , vol.7 , pp. 1435-1441
    • Henriksen, E.J.1    Dokken, B.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.