-
1
-
-
33745529808
-
New aspects of diagnosis and therapy of hepatocellular carcinoma
-
Bruix J., Hessheimer A.J., Forner A., Boix L., Vilana R., and Llovet J.M. New aspects of diagnosis and therapy of hepatocellular carcinoma. Oncogene 25 (2006) 3848-3856
-
(2006)
Oncogene
, vol.25
, pp. 3848-3856
-
-
Bruix, J.1
Hessheimer, A.J.2
Forner, A.3
Boix, L.4
Vilana, R.5
Llovet, J.M.6
-
3
-
-
21044445452
-
Apoptosis: a mechanism of acute and chronic liver injury
-
Guicciardi M.E., and Gores G.J. Apoptosis: a mechanism of acute and chronic liver injury. Gut 54 (2005) 1024-1033
-
(2005)
Gut
, vol.54
, pp. 1024-1033
-
-
Guicciardi, M.E.1
Gores, G.J.2
-
4
-
-
14744304730
-
Modulation of apoptosis as a target for liver disease
-
Eichhorst S.T. Modulation of apoptosis as a target for liver disease. Expert Opin Ther Targets 9 (2005) 83-99
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 83-99
-
-
Eichhorst, S.T.1
-
5
-
-
0030035921
-
Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues
-
Higaki K., Yano H., and Kojiro M. Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues. Am J Pathol 149 (1996) 429-437
-
(1996)
Am J Pathol
, vol.149
, pp. 429-437
-
-
Higaki, K.1
Yano, H.2
Kojiro, M.3
-
6
-
-
0034098493
-
The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma
-
Ito Y., Monden M., Takeda T., Eguchi H., Umeshita K., Nagano H., et al. The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma. Br J Cancer 82 (2000) 1211-1217
-
(2000)
Br J Cancer
, vol.82
, pp. 1211-1217
-
-
Ito, Y.1
Monden, M.2
Takeda, T.3
Eguchi, H.4
Umeshita, K.5
Nagano, H.6
-
7
-
-
16144363507
-
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?
-
Strand S., Hofmann W.J., Hug H., Muller M., Otto G., Strand D., et al. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - a mechanism of immune evasion?. Nat Med 2 (1996) 1361-1366
-
(1996)
Nat Med
, vol.2
, pp. 1361-1366
-
-
Strand, S.1
Hofmann, W.J.2
Hug, H.3
Muller, M.4
Otto, G.5
Strand, D.6
-
8
-
-
0036895749
-
TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells
-
Kim Y.S., Schwabe R.F., Qian T., Lemasters J.J., and Brenner D.A. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36 (2002) 1498-1508
-
(2002)
Hepatology
, vol.36
, pp. 1498-1508
-
-
Kim, Y.S.1
Schwabe, R.F.2
Qian, T.3
Lemasters, J.J.4
Brenner, D.A.5
-
9
-
-
0033839749
-
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
-
Yamanaka T., Shiraki K., Sugimoto K., Ito T., Fujikawa K., Ito M., et al. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 32 (2000) 482-490
-
(2000)
Hepatology
, vol.32
, pp. 482-490
-
-
Yamanaka, T.1
Shiraki, K.2
Sugimoto, K.3
Ito, T.4
Fujikawa, K.5
Ito, M.6
-
10
-
-
0037204818
-
Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
-
Shin E.C., Seong Y.R., Kim C.H., Kim H., Ahn Y.S., Kim K., et al. Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Exp Mol Med 34 (2002) 114-122
-
(2002)
Exp Mol Med
, vol.34
, pp. 114-122
-
-
Shin, E.C.1
Seong, Y.R.2
Kim, C.H.3
Kim, H.4
Ahn, Y.S.5
Kim, K.6
-
11
-
-
4344607589
-
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
-
Ganten T.M., Haas T.L., Sykora J., Stahl H., Sprick M.R., Fas S.C., et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ 11 Suppl. 1 (2004) S86-S96
-
(2004)
Cell Death Differ
, vol.11 SUPPL. 1
-
-
Ganten, T.M.1
Haas, T.L.2
Sykora, J.3
Stahl, H.4
Sprick, M.R.5
Fas, S.C.6
-
12
-
-
0042809497
-
Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma
-
Okano H., Shiraki K., Inoue H., Kawakita T., Yamanaka T., Deguchi M., et al. Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma. Lab Invest 83 (2003) 1033-1043
-
(2003)
Lab Invest
, vol.83
, pp. 1033-1043
-
-
Okano, H.1
Shiraki, K.2
Inoue, H.3
Kawakita, T.4
Yamanaka, T.5
Deguchi, M.6
-
13
-
-
0034950640
-
Expression and role of Bcl-xL in human hepatocellular carcinomas
-
Takehara T., Liu X., Fujimoto J., Friedman S.L., and Takahashi H. Expression and role of Bcl-xL in human hepatocellular carcinomas. Hepatology 34 (2001) 55-61
-
(2001)
Hepatology
, vol.34
, pp. 55-61
-
-
Takehara, T.1
Liu, X.2
Fujimoto, J.3
Friedman, S.L.4
Takahashi, H.5
-
14
-
-
17544373837
-
Survivin promotes cell proliferation in human hepatocellular carcinoma
-
Ito T., Shiraki K., Sugimoto K., Yamanaka T., Fujikawa K., Ito M., et al. Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology 31 (2000) 1080-1085
-
(2000)
Hepatology
, vol.31
, pp. 1080-1085
-
-
Ito, T.1
Shiraki, K.2
Sugimoto, K.3
Yamanaka, T.4
Fujikawa, K.5
Ito, M.6
-
15
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., and Woodgett J.R. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406 (2000) 86-90
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
16
-
-
0036081578
-
Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes
-
Schwabe R.F., and Brenner D.A. Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes. Am J Physiol Gastrointest Liver Physiol 283 (2002) G204-G211
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Schwabe, R.F.1
Brenner, D.A.2
-
17
-
-
2642523803
-
Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor
-
Song L., Zhou T., and Jope R.S. Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor. BMC Neurosci 5 (2004) 20
-
(2004)
BMC Neurosci
, vol.5
, pp. 20
-
-
Song, L.1
Zhou, T.2
Jope, R.S.3
-
18
-
-
2542425324
-
Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer
-
Liao X., Zhang L., Thrasher J.B., Du J., and Li B. Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer. Mol Cancer Ther 2 (2003) 1215-1222
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1215-1222
-
-
Liao, X.1
Zhang, L.2
Thrasher, J.B.3
Du, J.4
Li, B.5
-
19
-
-
27244444199
-
A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function
-
Rottmann S., Wang Y., Nasoff M., Deveraux Q.L., and Quon K.C. A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function. Proc Natl Acad Sci U S A 102 (2005) 15195-15200
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15195-15200
-
-
Rottmann, S.1
Wang, Y.2
Nasoff, M.3
Deveraux, Q.L.4
Quon, K.C.5
-
20
-
-
0032721833
-
Phase I and phase II drug-metabolizing enzymes are expressed and heterogeneously distributed in the biliary epithelium
-
Lakehal F., Wendum D., Barbu V., Becquemont L., Poupon R., Balladur P., et al. Phase I and phase II drug-metabolizing enzymes are expressed and heterogeneously distributed in the biliary epithelium. Hepatology 30 (1999) 1498-1506
-
(1999)
Hepatology
, vol.30
, pp. 1498-1506
-
-
Lakehal, F.1
Wendum, D.2
Barbu, V.3
Becquemont, L.4
Poupon, R.5
Balladur, P.6
-
21
-
-
0035843148
-
Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
-
Desbois-Mouthon C., Cadoret A., Blivet-Van Eggelpoel M.J., Bertrand F., Cherqui G., Perret C., et al. Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 20 (2001) 252-259
-
(2001)
Oncogene
, vol.20
, pp. 252-259
-
-
Desbois-Mouthon, C.1
Cadoret, A.2
Blivet-Van Eggelpoel, M.J.3
Bertrand, F.4
Cherqui, G.5
Perret, C.6
-
22
-
-
0037069330
-
Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways
-
Martinez L.A., Naguibneva I., Lehrmann H., Vervisch A., Tchenio T., Lozano G., et al. Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. Proc Natl Acad Sci U S A 99 (2002) 14849-14854
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14849-14854
-
-
Martinez, L.A.1
Naguibneva, I.2
Lehrmann, H.3
Vervisch, A.4
Tchenio, T.5
Lozano, G.6
-
23
-
-
0033588815
-
Reciprocal enhancement of gene transfer by combinatorial adenovirus transduction and plasmid DNA transfection in vitro and in vivo
-
Dunphy E.J., Redman R.A., Herweijer H., and Cripe T.P. Reciprocal enhancement of gene transfer by combinatorial adenovirus transduction and plasmid DNA transfection in vitro and in vivo. Hum Gene Ther 10 (1999) 2407-2417
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2407-2417
-
-
Dunphy, E.J.1
Redman, R.A.2
Herweijer, H.3
Cripe, T.P.4
-
24
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 93 (1996) 8455-8459
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
25
-
-
0033776383
-
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
-
Coghlan M.P., Culbert A.A., Cross D.A., Corcoran S.L., Yates J.W., Pearce N.J., et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem Biol 7 (2000) 793-803
-
(2000)
Chem Biol
, vol.7
, pp. 793-803
-
-
Coghlan, M.P.1
Culbert, A.A.2
Cross, D.A.3
Corcoran, S.L.4
Yates, J.W.5
Pearce, N.J.6
-
26
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M., Wilder S., Bannasch D., Israeli D., Lehlbach K., Li-Weber M., et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 188 (1998) 2033-2045
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
-
27
-
-
9244237679
-
TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
-
Hao C., Song J.H., Hsi B., Lewis J., Song D.K., Petruk K.C., et al. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res 64 (2004) 8502-8506
-
(2004)
Cancer Res
, vol.64
, pp. 8502-8506
-
-
Hao, C.1
Song, J.H.2
Hsi, B.3
Lewis, J.4
Song, D.K.5
Petruk, K.C.6
-
28
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D., Shahrokh Z., Marsters S., Achilles K., Shih D., Mounho B., et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 7 (2001) 383-385
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
-
29
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
-
Ganten T.M., Koschny R., Sykora J., Schulze-Bergkamen H., Buchler P., Haas T.L., et al. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 12 (2006) 2640-2646
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
Schulze-Bergkamen, H.4
Buchler, P.5
Haas, T.L.6
-
31
-
-
0037444380
-
Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel
-
Asakuma J., Sumitomo M., Asano T., and Hayakawa M. Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel. Cancer Res 63 (2003) 1365-1370
-
(2003)
Cancer Res
, vol.63
, pp. 1365-1370
-
-
Asakuma, J.1
Sumitomo, M.2
Asano, T.3
Hayakawa, M.4
-
32
-
-
34047258345
-
Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway
-
Pespeni M.H., Hodnett M., Abayasiriwardana K.S., Roux J., Howard M., Broaddus V.C., et al. Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway. Cancer Res 67 (2007) 2865-2871
-
(2007)
Cancer Res
, vol.67
, pp. 2865-2871
-
-
Pespeni, M.H.1
Hodnett, M.2
Abayasiriwardana, K.S.3
Roux, J.4
Howard, M.5
Broaddus, V.C.6
-
33
-
-
34848876387
-
15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation
-
Han H., Shin S.W., Seo C.Y., Kwon H.C., Han J.Y., Kim I.H., et al. 15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation. Apoptosis 12 (2007) 2101-2114
-
(2007)
Apoptosis
, vol.12
, pp. 2101-2114
-
-
Han, H.1
Shin, S.W.2
Seo, C.Y.3
Kwon, H.C.4
Han, J.Y.5
Kim, I.H.6
-
34
-
-
1942436864
-
Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells
-
He Q., Huang Y., and Sheikh M.S. Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells. Oncogene 23 (2004) 2554-2558
-
(2004)
Oncogene
, vol.23
, pp. 2554-2558
-
-
He, Q.1
Huang, Y.2
Sheikh, M.S.3
-
35
-
-
2942565827
-
Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications
-
Shankar S., and Srivastava R.K. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist Updat 7 (2004) 139-156
-
(2004)
Drug Resist Updat
, vol.7
, pp. 139-156
-
-
Shankar, S.1
Srivastava, R.K.2
-
36
-
-
16644381453
-
Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells
-
Inoue H., Shiraki K., Murata K., Sugimoto K., Kawakita T., Yamaguchi Y., et al. Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells. Int J Mol Med 14 (2004) 271-275
-
(2004)
Int J Mol Med
, vol.14
, pp. 271-275
-
-
Inoue, H.1
Shiraki, K.2
Murata, K.3
Sugimoto, K.4
Kawakita, T.5
Yamaguchi, Y.6
-
37
-
-
33748291763
-
Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway
-
Hu H., Jiang C., Schuster T., Li G.X., Daniel P.T., and Lu J. Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway. Mol Cancer Ther 5 (2006) 1873-1882
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1873-1882
-
-
Hu, H.1
Jiang, C.2
Schuster, T.3
Li, G.X.4
Daniel, P.T.5
Lu, J.6
-
38
-
-
33845349483
-
Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment
-
McKee C.M., Ye Y., and Richburg J.H. Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment. Apoptosis 11 (2006) 2237-2250
-
(2006)
Apoptosis
, vol.11
, pp. 2237-2250
-
-
McKee, C.M.1
Ye, Y.2
Richburg, J.H.3
-
39
-
-
34249106201
-
Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells
-
Secchiero P., Zerbinati C., di Iasio M.G., Melloni E., Tiribelli M., Grill V., et al. Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells. Curr Drug Metab 8 (2007) 395-403
-
(2007)
Curr Drug Metab
, vol.8
, pp. 395-403
-
-
Secchiero, P.1
Zerbinati, C.2
di Iasio, M.G.3
Melloni, E.4
Tiribelli, M.5
Grill, V.6
-
40
-
-
27144557493
-
Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta
-
Pluquet O., Qu L.K., Baltzis D., and Koromilas A.E. Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta. Mol Cell Biol 25 (2005) 9392-9405
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9392-9405
-
-
Pluquet, O.1
Qu, L.K.2
Baltzis, D.3
Koromilas, A.E.4
-
41
-
-
23344447873
-
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
-
Kulikov R., Boehme K.A., and Blattner C. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Mol Cell Biol 25 (2005) 7170-7180
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7170-7180
-
-
Kulikov, R.1
Boehme, K.A.2
Blattner, C.3
-
42
-
-
0442274617
-
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
-
Watcharasit P., Bijur G.N., Song L., Zhu J., Chen X., and Jope R.S. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem 278 (2003) 48872-48879
-
(2003)
J Biol Chem
, vol.278
, pp. 48872-48879
-
-
Watcharasit, P.1
Bijur, G.N.2
Song, L.3
Zhu, J.4
Chen, X.5
Jope, R.S.6
-
43
-
-
6044240634
-
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
-
Nakshatri H., Rice S.E., and Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 23 (2004) 7330-7344
-
(2004)
Oncogene
, vol.23
, pp. 7330-7344
-
-
Nakshatri, H.1
Rice, S.E.2
Bhat-Nakshatri, P.3
-
44
-
-
33646271827
-
1-Methoxy-canthin-6-one induces c-Jun NH2-terminal kinase-dependent apoptosis and synergizes with tumor necrosis factor-related apoptosis-inducing ligand activity in human neoplastic cells of hematopoietic or endodermal origin
-
Ammirante M., Di Giacomo R., De Martino L., Rosati A., Festa M., Gentilella A., et al. 1-Methoxy-canthin-6-one induces c-Jun NH2-terminal kinase-dependent apoptosis and synergizes with tumor necrosis factor-related apoptosis-inducing ligand activity in human neoplastic cells of hematopoietic or endodermal origin. Cancer Res 66 (2006) 4385-4393
-
(2006)
Cancer Res
, vol.66
, pp. 4385-4393
-
-
Ammirante, M.1
Di Giacomo, R.2
De Martino, L.3
Rosati, A.4
Festa, M.5
Gentilella, A.6
-
45
-
-
0037743569
-
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase
-
Sah N.K., Munshi A., Kurland J.F., McDonnell T.J., Su B., and Meyn R.E. Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase. J Biol Chem 278 (2003) 20593-20602
-
(2003)
J Biol Chem
, vol.278
, pp. 20593-20602
-
-
Sah, N.K.1
Munshi, A.2
Kurland, J.F.3
McDonnell, T.J.4
Su, B.5
Meyn, R.E.6
-
46
-
-
0037815359
-
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells
-
Vivo C., Liu W., and Broaddus V.C. c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells. J Biol Chem 278 (2003) 25461-25467
-
(2003)
J Biol Chem
, vol.278
, pp. 25461-25467
-
-
Vivo, C.1
Liu, W.2
Broaddus, V.C.3
-
47
-
-
0037853146
-
Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1)
-
Kim J.W., Lee J.E., Kim M.J., Cho E.G., Cho S.G., and Choi E.J. Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J Biol Chem 278 (2003) 13995-14001
-
(2003)
J Biol Chem
, vol.278
, pp. 13995-14001
-
-
Kim, J.W.1
Lee, J.E.2
Kim, M.J.3
Cho, E.G.4
Cho, S.G.5
Choi, E.J.6
-
48
-
-
0032705688
-
Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo
-
Yuan P., Chen G., and Manji H.K. Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo. J Neurochem 73 (1999) 2299-2309
-
(1999)
J Neurochem
, vol.73
, pp. 2299-2309
-
-
Yuan, P.1
Chen, G.2
Manji, H.K.3
-
49
-
-
10944237268
-
Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase
-
Liu S., Yu S., Hasegawa Y., Lapushin R., Xu H.J., Woodgett J.R., et al. Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. J Biol Chem 279 (2004) 51075-51081
-
(2004)
J Biol Chem
, vol.279
, pp. 51075-51081
-
-
Liu, S.1
Yu, S.2
Hasegawa, Y.3
Lapushin, R.4
Xu, H.J.5
Woodgett, J.R.6
-
50
-
-
22244479745
-
Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase
-
Gaillard P., Jeanclaude-Etter I., Ardissone V., Arkinstall S., Cambet Y., Camps M., et al. Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase. J Med Chem 48 (2005) 4596-4607
-
(2005)
J Med Chem
, vol.48
, pp. 4596-4607
-
-
Gaillard, P.1
Jeanclaude-Etter, I.2
Ardissone, V.3
Arkinstall, S.4
Cambet, Y.5
Camps, M.6
-
51
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A 98 (2001) 13681-13686
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
-
52
-
-
33644832724
-
Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents
-
Rowinsky E.K. Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents. J Clin Oncol 23 (2005) 9394-9407
-
(2005)
J Clin Oncol
, vol.23
, pp. 9394-9407
-
-
Rowinsky, E.K.1
-
53
-
-
51449118394
-
Targeting TRAIL death receptors
-
Oldenhuis C., Stegehuis J., Walenkamp A., de Jong S., and de Vries E. Targeting TRAIL death receptors. Curr Opin Pharmacol 8 (2008) 433-439
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 433-439
-
-
Oldenhuis, C.1
Stegehuis, J.2
Walenkamp, A.3
de Jong, S.4
de Vries, E.5
-
54
-
-
42949086433
-
Cellular and molecular mechanisms of liver injury
-
Malhi H., and Gores G.J. Cellular and molecular mechanisms of liver injury. Gastroenterology 134 (2008) 1641-1654
-
(2008)
Gastroenterology
, vol.134
, pp. 1641-1654
-
-
Malhi, H.1
Gores, G.J.2
-
55
-
-
52049094596
-
Differential regulation of STAT family members by glycogen synthase kinase-3
-
Beurel E., and Jope R.S. Differential regulation of STAT family members by glycogen synthase kinase-3. J Biol Chem 283 (2008) 21934-21944
-
(2008)
J Biol Chem
, vol.283
, pp. 21934-21944
-
-
Beurel, E.1
Jope, R.S.2
-
56
-
-
33947597084
-
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics
-
Jope R.S., Yuskaitis C.J., and Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 32 (2007) 577-595
-
(2007)
Neurochem Res
, vol.32
, pp. 577-595
-
-
Jope, R.S.1
Yuskaitis, C.J.2
Beurel, E.3
-
57
-
-
33750994327
-
Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis
-
Inoue S., Twiddy D., Dyer M.J., and Cohen G.M. Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis. Cell Death Differ 13 (2006) 2160-2162
-
(2006)
Cell Death Differ
, vol.13
, pp. 2160-2162
-
-
Inoue, S.1
Twiddy, D.2
Dyer, M.J.3
Cohen, G.M.4
-
58
-
-
85047695600
-
Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis
-
Kim J.Y., Kim Y.H., Chang I., Kim S., Pak Y.K., Oh B.H., et al. Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis. Oncogene 21 (2002) 3139-3148
-
(2002)
Oncogene
, vol.21
, pp. 3139-3148
-
-
Kim, J.Y.1
Kim, Y.H.2
Chang, I.3
Kim, S.4
Pak, Y.K.5
Oh, B.H.6
-
59
-
-
0037910211
-
The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death
-
Czaja M.J. The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death. Am J Physiol Gastrointest Liver Physiol 284 (2003) G875-G879
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Czaja, M.J.1
-
60
-
-
0346422479
-
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1
-
Higuchi H., Grambihler A., Canbay A., Bronk S.F., and Gores G.J. Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem 279 (2004) 51-60
-
(2004)
J Biol Chem
, vol.279
, pp. 51-60
-
-
Higuchi, H.1
Grambihler, A.2
Canbay, A.3
Bronk, S.F.4
Gores, G.J.5
-
61
-
-
0037308871
-
Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells
-
Bae M.A., and Song B.J. Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells. Mol Pharmacol 63 (2003) 401-408
-
(2003)
Mol Pharmacol
, vol.63
, pp. 401-408
-
-
Bae, M.A.1
Song, B.J.2
-
62
-
-
33745758229
-
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity
-
Gunawan B.K., Liu Z.X., Han D., Hanawa N., Gaarde W.A., and Kaplowitz N. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gastroenterology 131 (2006) 165-178
-
(2006)
Gastroenterology
, vol.131
, pp. 165-178
-
-
Gunawan, B.K.1
Liu, Z.X.2
Han, D.3
Hanawa, N.4
Gaarde, W.A.5
Kaplowitz, N.6
-
63
-
-
0032979438
-
Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
-
Behrens A., Sibilia M., and Wagner E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21 (1999) 326-329
-
(1999)
Nat Genet
, vol.21
, pp. 326-329
-
-
Behrens, A.1
Sibilia, M.2
Wagner, E.F.3
-
64
-
-
0036329891
-
Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells
-
Liedtke C., Plumpe J., Kubicka S., Bradham C.A., Manns M.P., Brenner D.A., et al. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology 36 (2002) 315-325
-
(2002)
Hepatology
, vol.36
, pp. 315-325
-
-
Liedtke, C.1
Plumpe, J.2
Kubicka, S.3
Bradham, C.A.4
Manns, M.P.5
Brenner, D.A.6
-
65
-
-
48449090284
-
The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX
-
Aderca I., Moser C.D., Veerasamy M., Bani-Hani A.H., Bonilla-Guerrero R., Ahmed K., et al. The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. J Hepatol 49 (2008) 373-383
-
(2008)
J Hepatol
, vol.49
, pp. 373-383
-
-
Aderca, I.1
Moser, C.D.2
Veerasamy, M.3
Bani-Hani, A.H.4
Bonilla-Guerrero, R.5
Ahmed, K.6
-
66
-
-
33748299477
-
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
-
Beurel E., and Jope R.S. The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog Neurobiol 79 (2006) 173-189
-
(2006)
Prog Neurobiol
, vol.79
, pp. 173-189
-
-
Beurel, E.1
Jope, R.S.2
-
67
-
-
33750866196
-
Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions
-
Jope R.S., and Roh M.S. Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr Drug Targets 7 (2006) 1421-1434
-
(2006)
Curr Drug Targets
, vol.7
, pp. 1421-1434
-
-
Jope, R.S.1
Roh, M.S.2
-
68
-
-
33750881942
-
Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes
-
Henriksen E.J., and Dokken B.B. Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes. Curr Drug Targets 7 (2006) 1435-1441
-
(2006)
Curr Drug Targets
, vol.7
, pp. 1435-1441
-
-
Henriksen, E.J.1
Dokken, B.B.2
-
69
-
-
24644485965
-
GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis
-
Beurel E., Kornprobst M., Blivet-Van Eggelpoel M.J., Cadoret A., Capeau J., and Desbois-Mouthon C. GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis. Int J Oncol 27 (2005) 215-222
-
(2005)
Int J Oncol
, vol.27
, pp. 215-222
-
-
Beurel, E.1
Kornprobst, M.2
Blivet-Van Eggelpoel, M.J.3
Cadoret, A.4
Capeau, J.5
Desbois-Mouthon, C.6
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