Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues

American Journal of Pathology

Volumn 149, Issue 2, 1996, Pages 429-437

  Higaki, Koichi ^a   Yano, Hirohisa ^a   Kojiro, Masamichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ADULT; AGED; APOPTOSIS; ARTICLE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; ANTIGENS, CD95; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COUNT; FEMALE; HUMANS; LIVER DISEASES; LIVER NEOPLASMS; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED;

EID: 0030035921     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Suda T, Takahashi T, Golstein P, Nagata S: Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993, 75: 1169-1178
2. Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor. J Exp Med 1989, 169:1747-1756
3. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991, 66:233-243
4. Wong GHW, Goeddel DV: Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways. J Immunol 1994, 152:1751-1755
5. Owen-Schaub LB, Radinsky R, Kruzel E, Berry K, Yonehara S: Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness. Cancer Res 1994, 54:1580-1586
6. Watanabe-Fukunaga R, Brannan CI, Itoh N, Yonehara S, Copeland NG, Jenkins NA, Nagata S: The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 1992, 148:1274-1279
7. Morimoto H, Yonehara S, Bonavida B: Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins. Cancer Res 1993, 53: 2591-2596
8. Ogasawara J, Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugai T, Kitamura Y, Itoh N, Suda T, Nagata S: Lethal effect of the anti-Fas antibody in mice. Nature 1993, 364:806-809
9. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S: Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994, 76:969-976
10. Suda T, Nagata S: Purification and characterization of the Fas-ligand that induces apoptosis J Exp Med 1994, 179:873-879
11. Lowin B, Hahne M, Mattmann C, Tschopp J: Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 1994, 370:650-652
12. 2+-independent T cell-mediated cytotoxicity. J Exp Med 1993, 177:195-200
13. Kägi D, Vignaux F, Ledermann B, Bürki K, Depraetere V, Nagata S, Hengartner H. Golstein P: Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994, 265:528-530
14. Kojima H, Shinohara N, Hanaoka S, Someya-Shirota Y, Takagaki Y, Ohno H, Saito T, Katayama T, Yagita H, Okumura K: Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1994 1:357-364
15. Wyllie AH, Kerr JFR, Currie AR: Cell death: the significance of apoptosis Int Rev Cytol 1980, 68:251-306
16. Kerr JFR, Harmon BV: Definition and incidence of apoptosis: an historical perspective. Apoptosis: The Molecular Basis of Cell Death. Edited by LD Tomein, FO Cope. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1991, pp 5-29
17. Alderson MR, Armitage RJ, Maraskovsky E, Tough TW, Roux E, Schooley K, Ramsdell F, Lynch DH: Fas transduces activation signals in normal human T lymphocytes. J Exp Med 1993, 178:2231-2235
18. Iwai K, Miyawaki T, Takizawa T, Konno A, Ohta K, Yachie A, Seki H, Taniguchi N: Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 1994, 84:1201-1208
19. Mysler E, Bini P, Drappa J, Ramos P, Friedman SM, Krammer PH, Elkon KB: The apoptosis-1/Fas protein in human systemic lupus erythematosus. J Clin Invest 1994, 93:1029-1034
20. Kobayashi N, Hamamoto Y, Yamamoto N, Ishii A, Yonehara M, Yonehara S: Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication. Proc Natl Acad Sci USA 1990, 87:9620-9624
21. Yoshino T, Kondo E, Cao L, Takahashi K, Hayashi K, Nomura S, Akagi T: Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes. Blood 1994, 83:1856-1861
22. Falk MH, Trauth BC, Debatin K-M, Klas C, Gregory CD, Rickinson AB, Calender A, Lenoir GM, Ellwart JW, Krammer PH, Bornkamm GW: Expression of the APO-1 antigen in Burkitt lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype. Blood 1992, 79:3300-3306
23. Owen-Schaub LB, Yonehara S, Crump WL III, Grimm EA: DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 1992, 140:197-205
24. Weller M, Frei K, Groscurth P, Krammer PH, Yonekawa Y, Fontana A: Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells: induction and modulation of sensitivity by cytokines. J Clin Invest 1994, 94:954-964
25. Yano H, Fukuda K, Haramaki M, Momosaki S, Ogasawara S, Higaki K, Kojiro M: Expression of Fas and anti-Fas-mediated apoptosis in human hepatocellular carcinoma cell lines. J Hepatol 1996 (in press)
26. Yano H, Iemura A, Fukuda K, Haramaki M, Momosaki S, Ogasawara S, Higaki K, Kojiro M: Enhancement of anti-Fas antigen-mediated apoptosis in human hepatocellular carcinoma cell lines in the presence of the protein synthesis inhibitor cycloheximide. Int Hepatol Commun (Suppl) 1995, 3:S146
27. Hiramatsu N, Hayashi N, Katayama K, Mochizuki K, Kawanishi Y, Kasahara A, Fusamoto H, Kamada T: Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 1994, 19:1354-1359
28. Leithäuser F, Dhein J, Mechtersheimer G, Koretz K, Brüderlein S, Henne C, Schmidt A, Debatin K-M, Krammer PH, Möller P: Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 1993, 69:415-429
29. Okazaki M, Hino K, Fujii K, Hanada H, Nakanishi Y, Kanazawa S, Kobayashi N, Okita K: Immunohistochemical study of Fas antigen in liver of patients with chronic hepatitis and autoimmune liver disease. Int Hepatol Commun 1995, 3:285-289
30. Searle CJ, Harmon BV, Bishop J, Kerr JFR: The significance of cell death by apoptosis in hepatobiliary disease. J Gastroenterol Hepatol 1987, 2:77-96
31. Benedetti A, Jézéquel AM, Orlandi F: Preferential distribution of apoptotic bodies in acinar zone 3 of normal human and rat liver. J Hepatol 1988, 7:319-324
32. Tsugeno H, Yamada G. Takatani M, Kishi F, Doi T, Takaguchi K, Manabe K, Yonehara S, Tsuji T: Immunohistochemical study of Fas antigen in human liver tissues. Hepatology 1994, 20:145A
33. Natoli G, Ianni A, Costanzo A, De Petrillo G, Ilari I, Chirillo P, Balsono C, Levrero M: Resistance to Fas-mediated apoptosis in human hepatoma cells. Oncogene 1995, 11:1157-1164
34. The Liver Cancer Study Group of Japan: Primary liver cancer in Japan: clinicopathologic features and results of surgical treatment. Ann Surg 1990, 211:277-287
35. Kerr JFR, Winterford CM, Harmon BV: Apoptosis: its significance in cancer and cancer therapy. Cancer 1994, 73:2013-2026
36. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-257
37. Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, Barr PJ, Mountz JD: Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 1994, 263:1759-1762
38. Taniuchi M, Clark HB, Johnson EM Jr: Induction of nerve growth factor receptor in Schwann cells after axotomy. Proc Natl Acad Sci USA 1986, 83:4094-4098
39. + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lprllpr. Proc Natl Acad Sci USA 1993, 90:10340-10344
40. Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S: Expression of the Fas ligand in cells of T cell lineage. J Immunol 1995, 154:3806-3813
41. Hanabuchi S, Koyanagi M, Kawasaki A, Shinohara N, Matsuzawa A, Nishimura Y, Kobayashi Y, Yonehara S, Yagita H, Okamura K: Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci USA 1994, 91:4930-4934
42. Mita E, Hayashi N, Iio S, Takehara T, Hijioka T, Kasahara A, Fusamoto H, Kamada T: Role of Fas ligand in apoptosis induced by hepatitis C virus infection. Biochem Biophys Res Commun 1994, 204: 468-474
43. Weller M, Malipiero U, Aguzzi A, Reed JC, Fontana A: Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemother-apeutic drugs and therapeutic irradiation. J Clin Invest 1995, 95:2633-2643