-
1
-
-
0037372154
-
Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man
-
Agrawal NG, Porras AG, Matthews CZ, et al. 2003. Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man. J Clin Pharmacol, 43:268-76.
-
(2003)
J Clin Pharmacol
, vol.43
, pp. 268-276
-
-
Agrawal, N.G.1
Porras, A.G.2
Matthews, C.Z.3
-
2
-
-
33747466079
-
Prostanoid signal transduction and gene expression in the endothelium: Role in cardiovascular diseases
-
Alfranca A, Iñiguez MA, Fresno M, et al. 2006. Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases. Cardiovasc Res, 70:446-56.
-
(2006)
Cardiovasc Res
, vol.70
, pp. 446-456
-
-
Alfranca, A.1
Iñiguez, M.A.2
Fresno, M.3
-
3
-
-
34247464709
-
Use of nonsteroidal antiinflammatory drugs: An update for clinicians: a scientific statement from the American Heart Association
-
Antman EM, Bennett JS, Daugherty A, et al. 2007. Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation, 115:1634-42.
-
(2007)
Circulation
, vol.115
, pp. 1634-1642
-
-
Antman, E.M.1
Bennett, J.S.2
Daugherty, A.3
-
4
-
-
42549150113
-
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: Potential implications for cyclooxygenase-2 inhibition
-
Arehart E, Stitham J, Asselbergs FW, et al. 2008. Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition. Circ Res, 102:986-93.
-
(2008)
Circ Res
, vol.102
, pp. 986-993
-
-
Arehart, E.1
Stitham, J.2
Asselbergs, F.W.3
-
5
-
-
0023945481
-
The American rheumatism association 1987 revised criteria for the classification of rheumatiod arthritis
-
Arnett FC, Edworthy SM, Bloch DA, et al. 1988. The American rheumatism association 1987 revised criteria for the classification of rheumatiod arthritis. Arthritis Rheum, 31:315-24.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
6
-
-
33745378736
-
Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells
-
Asano K, Lilly CM, Drazen JM. 1996. Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells. Am J Physiol Lung Cell Mol Physiol, 271:L126-31.
-
(1996)
Am J Physiol Lung Cell Mol Physiol
, vol.271
-
-
Asano, K.1
Lilly, C.M.2
Drazen, J.M.3
-
7
-
-
0030597962
-
Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation
-
Beiche F, Scheuerer S, Brune K, et al. 1996. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett, 390:165-9.
-
(1996)
FEBS Lett
, vol.390
, pp. 165-169
-
-
Beiche, F.1
Scheuerer, S.2
Brune, K.3
-
8
-
-
33847420941
-
Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo-controlled, non-inferiority studies
-
Bingham CO 3rd, Sebba AI, Rubin BR, et al. 2007. Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo-controlled, non-inferiority studies. Rheumatology (Oxford), 46:496-507.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 496-507
-
-
Bingham 3rd, C.O.1
Sebba, A.I.2
Rubin, B.R.3
-
9
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
-
Bresalier RS, Sandler RS, Quan H, et al. 2005. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med, 352:1092-102.
-
(2005)
N Engl J Med
, vol.352
, pp. 1092-1102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
-
11
-
-
33645296475
-
Analgesic-antipyretic agents; Pharmacotherapy of gout
-
Brunton LL, Lazo JS, Parker KL, ed, 11th ed. New York, USA, McGRAW-HILL, Medical Publishing Division. p
-
Burke A, Smyth E, FitzGerald GA. 2006. Analgesic-antipyretic agents; Pharmacotherapy of gout. In: Brunton LL, Lazo JS, Parker KL. (ed) Goodman and Gilman's The Pharmacological Basis of Therapeutics. 11th ed. New York, USA, McGRAW-HILL, Medical Publishing Division. p673-715.
-
(2006)
Goodman and Gilman's The Pharmacological Basis of Therapeutics
, pp. 673-715
-
-
Burke, A.1
Smyth, E.2
FitzGerald, G.A.3
-
12
-
-
33750944984
-
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: A randomised comparison
-
Cannon CP, Curtis SP, FitzGerald GA, et al. 2006. Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet, 368:1771-81.
-
(2006)
Lancet
, vol.368
, pp. 1771-1781
-
-
Cannon, C.P.1
Curtis, S.P.2
FitzGerald, G.A.3
-
13
-
-
38949197394
-
Cardiovascular effects of valdecoxib: Transducing human pharmacology results into clinical read-outs
-
Capone ML, Tacconelli S, Francesco LD, et al. 2008. Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs. Expert Opin Drug Saf, 7:29-42.
-
(2008)
Expert Opin Drug Saf
, vol.7
, pp. 29-42
-
-
Capone, M.L.1
Tacconelli, S.2
Francesco, L.D.3
-
15
-
-
12144290072
-
Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects
-
Capone ML, Tacconelli S, Sciulli MG, et al. 2004. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. Circulation, 109:1468-71.
-
(2004)
Circulation
, vol.109
, pp. 1468-1471
-
-
Capone, M.L.1
Tacconelli, S.2
Sciulli, M.G.3
-
16
-
-
2942592703
-
Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a
-
Carlson ML, Wilson ET, Prescott SM. 2003. Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a. Mol Cancer, 2:42.
-
(2003)
Mol Cancer
, vol.2
, pp. 42
-
-
Carlson, M.L.1
Wilson, E.T.2
Prescott, S.M.3
-
17
-
-
0032948948
-
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
-
Catella-Lawson F, McAdam B, Morrison BW, et al. 1999. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J Pharmacol Exp Ther, 289:735-41.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 735-741
-
-
Catella-Lawson, F.1
McAdam, B.2
Morrison, B.W.3
-
18
-
-
0032076219
-
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs
-
Cryer B, Feldman M. 1998. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. Am J Med, 104:413-21.
-
(1998)
Am J Med
, vol.104
, pp. 413-421
-
-
Cryer, B.1
Feldman, M.2
-
19
-
-
10344267004
-
COX-2-derived prostacyclin confers atheroprotection on female mice
-
Egan KM, Lawson JA, Fries S, et al. 2004. COX-2-derived prostacyclin confers atheroprotection on female mice. Science, 306:1954-7.
-
(2004)
Science
, vol.306
, pp. 1954-1957
-
-
Egan, K.M.1
Lawson, J.A.2
Fries, S.3
-
20
-
-
0035833502
-
The Coxibs, selective inhibitors of Cyclooxygenase-2
-
Fitzgerald GA, Patrono C. 2001. The Coxibs, selective inhibitors of Cyclooxygenase-2. N Engl J Med, 345:433-42.
-
(2001)
N Engl J Med
, vol.345
, pp. 433-442
-
-
Fitzgerald, G.A.1
Patrono, C.2
-
21
-
-
0242690224
-
COX-2 and beyond: Approaches to prostaglandin inhibition in human disease
-
FitzGerald GA. 2003. COX-2 and beyond: Approaches to prostaglandin inhibition in human disease. Nat Rev Drug Discov, 2:879-90.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 879-890
-
-
FitzGerald, G.A.1
-
22
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
Funk CD. 2001. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science, 294:1871-5.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
23
-
-
31044441042
-
Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities
-
Grosser T, Fries S, FitzGerald GA. 2006. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest, 116:4-15.
-
(2006)
J Clin Invest
, vol.116
, pp. 4-15
-
-
Grosser, T.1
Fries, S.2
FitzGerald, G.A.3
-
24
-
-
0028034970
-
Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
-
Harris RC, McKanna JA, Akai Y, et al. 1994. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. Clin Invest, 94:2504-10.
-
(1994)
Clin Invest
, vol.94
, pp. 2504-2510
-
-
Harris, R.C.1
McKanna, J.A.2
Akai, Y.3
-
26
-
-
22844452700
-
Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
-
Huntjens DR, Danhof M, Della Pasqua OE. 2005. Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors. Rheumatology (Oxford), 44:846-59.
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 846-859
-
-
Huntjens, D.R.1
Danhof, M.2
Della Pasqua, O.E.3
-
27
-
-
0032589741
-
Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system
-
Inoue A, Ikoma K, Morioka N, et al. 1999. Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system. J Neurochem, 73:2206-13.
-
(1999)
J Neurochem
, vol.73
, pp. 2206-2213
-
-
Inoue, A.1
Ikoma, K.2
Morioka, N.3
-
28
-
-
34247505895
-
Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation
-
Kang YJ, Mbonye UR, DeLong CJ, et al. 2007. Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog Lipid Res, 46:108-25.
-
(2007)
Prog Lipid Res
, vol.46
, pp. 108-125
-
-
Kang, Y.J.1
Mbonye, U.R.2
DeLong, C.J.3
-
29
-
-
0030017042
-
Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts
-
Kargman S, Charleson S, Cartwright M, et al. 1996. Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology, 111:445-54.
-
(1996)
Gastroenterology
, vol.111
, pp. 445-454
-
-
Kargman, S.1
Charleson, S.2
Cartwright, M.3
-
30
-
-
0035000968
-
Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor
-
Kassahun K, McIntosh IS, Shou M, et al. 2001. Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor. Drug Metab Dispos, 29:813-20.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 813-820
-
-
Kassahun, K.1
McIntosh, I.S.2
Shou, M.3
-
31
-
-
0031051604
-
Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome
-
Kaufmann WE, Worley PF, Taylor CV, et al. 1997. Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome. Brain Dev, 19:25-34.
-
(1997)
Brain Dev
, vol.19
, pp. 25-34
-
-
Kaufmann, W.E.1
Worley, P.F.2
Taylor, C.V.3
-
32
-
-
33744976771
-
Do selective cyclooxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials
-
Kearney PM, Baigent C, Godwin J, et al. 2006. Do selective cyclooxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ, 332:1302-8.
-
(2006)
BMJ
, vol.332
, pp. 1302-1308
-
-
Kearney, P.M.1
Baigent, C.2
Godwin, J.3
-
34
-
-
0028810964
-
Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2
-
Kulmacz RJ, Wang LH. 1995. Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2. J Biol Chem, 270:24019-23.
-
(1995)
J Biol Chem
, vol.270
, pp. 24019-24023
-
-
Kulmacz, R.J.1
Wang, L.H.2
-
35
-
-
33846822336
-
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: A randomized comparison
-
Laine L, Curtis SP, Cryer B, et al. 2007. Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomized comparison. Lancet, 369:465-73.
-
(2007)
Lancet
, vol.369
, pp. 465-473
-
-
Laine, L.1
Curtis, S.P.2
Cryer, B.3
-
36
-
-
18344362986
-
Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: A randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trial
-
Leung AT, Malmstrom K, Gallacher AE, et al. 2002. Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: a randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trial. Curr Med Res Opin, 18:49-58.
-
(2002)
Curr Med Res Opin
, vol.18
, pp. 49-58
-
-
Leung, A.T.1
Malmstrom, K.2
Gallacher, A.E.3
-
37
-
-
0034665857
-
The productive conformation of arachidonic acid bound to prostaglandin synthase
-
Malkowski MG, Ginell SL, Smith WL, et al. 2000. The productive conformation of arachidonic acid bound to prostaglandin synthase. Science, 289:1933-7.
-
(2000)
Science
, vol.289
, pp. 1933-1937
-
-
Malkowski, M.G.1
Ginell, S.L.2
Smith, W.L.3
-
38
-
-
0033551847
-
Arachidonic acid oxygenation by COX-1 and COX-2: Mechanisms of catalysis and inhibition
-
Marnett LJ, Rowlinson SW, Goodwin DC, et al. 1999. Arachidonic acid oxygenation by COX-1 and COX-2: mechanisms of catalysis and inhibition. J Biol Chem, 274:22903-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 22903-22906
-
-
Marnett, L.J.1
Rowlinson, S.W.2
Goodwin, D.C.3
-
39
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
-
McAdam BF, Catella-Lawson F, Mardini IA, et al. 1999. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci U S A, 96:272-7.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
-
40
-
-
33751082074
-
Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets
-
Minuz P, Fumagalli L, Gaino S, et al. 2006. Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets. Biochem J, 400:127-34.
-
(2006)
Biochem J
, vol.400
, pp. 127-134
-
-
Minuz, P.1
Fumagalli, L.2
Gaino, S.3
-
41
-
-
0036257535
-
Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha
-
Minuz P, Gaino S, Zuliani V, et al. 2002. Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha. Thromb Haemost, 87:888-98.
-
(2002)
Thromb Haemost
, vol.87
, pp. 888-898
-
-
Minuz, P.1
Gaino, S.2
Zuliani, V.3
-
42
-
-
0017338997
-
Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation
-
Moncada S, Higgs EA, Vane JR. 1977. Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation. Lancet, 1:18-20.
-
(1977)
Lancet
, vol.1
, pp. 18-20
-
-
Moncada, S.1
Higgs, E.A.2
Vane, J.R.3
-
43
-
-
0030816051
-
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
-
Murata T, Ushikubi F, Matsuoka T, et al. 1997. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature, 388:678-82.
-
(1997)
Nature
, vol.388
, pp. 678-682
-
-
Murata, T.1
Ushikubi, F.2
Matsuoka, T.3
-
44
-
-
34547097777
-
CJ-023,423, a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties
-
Nakao K, Murase A, Ohshiro H, et al. 2007. CJ-023,423, a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. J Pharmacol Exp Ther, 322:686-94.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 686-694
-
-
Nakao, K.1
Murase, A.2
Ohshiro, H.3
-
45
-
-
12144289756
-
Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: A molecular pathway of H pylori-related gastric carcinogenesis
-
Nardone G, Rocco A, Vaira D, et al. 2004. Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis. J Pathol, 202:305-12.
-
(2004)
J Pathol
, vol.202
, pp. 305-312
-
-
Nardone, G.1
Rocco, A.2
Vaira, D.3
-
46
-
-
0032823306
-
Prostanoid receptors: Structures, properties, and functions
-
Narumiya S, Sugimoto Y, Ushikubi F. 1999. Prostanoid receptors: structures, properties, and functions. Physiol Rev, 79:1193-226.
-
(1999)
Physiol Rev
, vol.79
, pp. 1193-1226
-
-
Narumiya, S.1
Sugimoto, Y.2
Ushikubi, F.3
-
47
-
-
14944371100
-
Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
-
Nussmeier NA, Whelton AA, Brown MT, et al. 2005. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med, 352:1081-91.
-
(2005)
N Engl J Med
, vol.352
, pp. 1081-1091
-
-
Nussmeier, N.A.1
Whelton, A.A.2
Brown, M.T.3
-
48
-
-
0037635061
-
Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery
-
Ott E, Nussmeier NA, Duke PC, et al. 2003. Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery. J Thorac Cardiovasc Surg, 125:1481-92.
-
(2003)
J Thorac Cardiovasc Surg
, vol.125
, pp. 1481-1492
-
-
Ott, E.1
Nussmeier, N.A.2
Duke, P.C.3
-
50
-
-
25444462405
-
Lumiracoxib is a selective inhibitor of cyclooxygenase-2 in patients with osteoarthritis
-
Patrignani P, Campestrini J, Branson J, et al. 2004. Lumiracoxib is a selective inhibitor of cyclooxygenase-2 in patients with osteoarthritis. Ann Rheum Dis, 63: 368.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 368
-
-
Patrignani, P.1
Campestrini, J.2
Branson, J.3
-
51
-
-
53049083243
-
Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: A clinical biomarker study
-
Patrignani P, Di Febbo C, Tacconelli S, et al. 2008b. Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. Pharmacogenetics and Genomics, 18:611-20.
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, pp. 611-620
-
-
Patrignani, P.1
Di Febbo, C.2
Tacconelli, S.3
-
52
-
-
0027940487
-
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases
-
Patrignani P, Panara MR, Greco A, et al. 1994. Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther, 271:1705-12.
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1705-1712
-
-
Patrignani, P.1
Panara, M.R.2
Greco, A.3
-
53
-
-
0031456454
-
Differential inhibition of human prostaglandin endoperoxide synthase-1 and -2 by nonsteroidal anti-inflammatory drugs
-
Patrignani P, Panara MR, Sciulli MG, et al. 1997. Differential inhibition of human prostaglandin endoperoxide synthase-1 and -2 by nonsteroidal anti-inflammatory drugs. J Physiol Pharmacol, 48:623-31.
-
(1997)
J Physiol Pharmacol
, vol.48
, pp. 623-631
-
-
Patrignani, P.1
Panara, M.R.2
Sciulli, M.G.3
-
54
-
-
0033377768
-
COX-2 is not involved in thromboxane biosynthesis by activated human platelets
-
Patrignani P, Sciulli MG, Manarini S, et al. 1999. COX-2 is not involved in thromboxane biosynthesis by activated human platelets. J Physiol Pharmacol, 50:661-7.
-
(1999)
J Physiol Pharmacol
, vol.50
, pp. 661-667
-
-
Patrignani, P.1
Sciulli, M.G.2
Manarini, S.3
-
55
-
-
56749135816
-
-
Patrignani P, Tacconelli S, García Rodríguez LA. 2008a. Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. Arterioscler Thromb Vasc Biol, 28:e-45.
-
Patrignani P, Tacconelli S, García Rodríguez LA. 2008a. Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. Arterioscler Thromb Vasc Biol, 28:e-45.
-
-
-
-
56
-
-
0018830990
-
Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects
-
Patrono C, Ciabattoni G, Pinca E, et al. 1980. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. Thromb Res, 17:317-27.
-
(1980)
Thromb Res
, vol.17
, pp. 317-327
-
-
Patrono, C.1
Ciabattoni, G.2
Pinca, E.3
-
57
-
-
0034946873
-
Cyclooxygenase-selective inhibition of prostanoid formation: Transducing biochemical selectivity into clinical read-outs
-
Patrono C, Patrignani P, García Rodríguez LA. 2001. Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs. J Clin Invest, 108:7-13.
-
(2001)
J Clin Invest
, vol.108
, pp. 7-13
-
-
Patrono, C.1
Patrignani, P.2
García Rodríguez, L.A.3
-
58
-
-
56749145584
-
-
Pfizer. A double-blind randomised placebo-controlled comparative study of celecoxib (SC-58635) for the inhibition of progression of Alzheimer's disease, protocol IQ5-97-02-001.2000 [online]. Accessed 21 November 2005. URL: http://www.clinicalstudyresults.org/documents/ company-study_76_0.pdf
-
Pfizer. A double-blind randomised placebo-controlled comparative study of celecoxib (SC-58635) for the inhibition of progression of Alzheimer's disease, protocol IQ5-97-02-001.2000 [online]. Accessed 21 November 2005. URL: http://www.clinicalstudyresults.org/documents/ company-study_76_0.pdf
-
-
-
-
60
-
-
29244442937
-
Persistent production of platelet thromboxane A2 in patients chronically treated with aspirin
-
Pulcinelli FM, Riondino S, Celestini A, et al. 2005. Persistent production of platelet thromboxane A2 in patients chronically treated with aspirin. J Thromb Haemost, 3:2784-9.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 2784-2789
-
-
Pulcinelli, F.M.1
Riondino, S.2
Celestini, A.3
-
61
-
-
0036308753
-
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
-
Qi Z, Hao C-M, Langenbach RI, et al. 2002. Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. J Clin Invest, 110:61-9.
-
(2002)
J Clin Invest
, vol.110
, pp. 61-69
-
-
Qi, Z.1
Hao, C.-M.2
Langenbach, R.I.3
-
62
-
-
0019190328
-
Synthesis and metabolism of prostaglandins, prostacyclin, and thromboxanes: The arachidonic acid cascade
-
Ramwell PW, Foegh M, Loeb R, et al. 1980. Synthesis and metabolism of prostaglandins, prostacyclin, and thromboxanes: the arachidonic acid cascade. Semin Perinatol, 4:3-13.
-
(1980)
Semin Perinatol
, vol.4
, pp. 3-13
-
-
Ramwell, P.W.1
Foegh, M.2
Loeb, R.3
-
63
-
-
0023137593
-
Inhibition of thromboxane formation in vivo and ex vivo: Implications for therapy with platelet inhibitory drugs
-
Reilly IA, FitzGerald GA. 1987. Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs. Blood, 69:180-6.
-
(1987)
Blood
, vol.69
, pp. 180-186
-
-
Reilly, I.A.1
FitzGerald, G.A.2
-
64
-
-
0035145462
-
Etoricoxib (MK-0663): Preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2
-
Riendeau D, Percival MD, Brideau C, et al. 2001. Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. J Pharmacol Exp Ther, 296:558-66.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 558-566
-
-
Riendeau, D.1
Percival, M.D.2
Brideau, C.3
-
65
-
-
0141854494
-
Expression of cyclooxygenase-2 in human gastric carcinoma
-
Ristimaki A, Honkanen N, Jankala H, et al. 1997. Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res, 57:1276-80.
-
(1997)
Cancer Res
, vol.57
, pp. 1276-1280
-
-
Ristimaki, A.1
Honkanen, N.2
Jankala, H.3
-
67
-
-
3543047940
-
Dominance of cyclooxygenase-2 in the regulation of pancreatic islet prostaglandin synthesis
-
Robertson RP. 1998. Dominance of cyclooxygenase-2 in the regulation of pancreatic islet prostaglandin synthesis. Diabetes, 47:1379-83.
-
(1998)
Diabetes
, vol.47
, pp. 1379-1383
-
-
Robertson, R.P.1
-
68
-
-
0032696786
-
Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development
-
Rocca B, Spain LM, Pure E, et al. 1999. Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development. J Clin Invest, 103:1469-77.
-
(1999)
J Clin Invest
, vol.103
, pp. 1469-1477
-
-
Rocca, B.1
Spain, L.M.2
Pure, E.3
-
69
-
-
15644382984
-
Helicobacter pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN 28 gastric mucosal cells in vitro
-
Romano M, Ricci V, Memoli A, et al. 1998. Helicobacter pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN 28 gastric mucosal cells in vitro. J Biol Chem, 273:28560-3.
-
(1998)
J Biol Chem
, vol.273
, pp. 28560-28563
-
-
Romano, M.1
Ricci, V.2
Memoli, A.3
-
70
-
-
0035932121
-
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, et al. 2001. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature, 410:471-5.
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
-
71
-
-
33645668967
-
The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain
-
Sciulli MG, Capone ML, Tacconelli S, et al. 2005. The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain. Pharmacol Rep, 57:66-85.
-
(2005)
Pharmacol Rep
, vol.57
, pp. 66-85
-
-
Sciulli, M.G.1
Capone, M.L.2
Tacconelli, S.3
-
72
-
-
33746732228
-
Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease
-
Sciulli MG, Renda G, Capone ML, et al. 2006. Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease. Clin Pharmacol Ther, 80:115-25.
-
(2006)
Clin Pharmacol Ther
, vol.80
, pp. 115-125
-
-
Sciulli, M.G.1
Renda, G.2
Capone, M.L.3
-
73
-
-
0034721853
-
Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
-
Shao J, Sheng H, Inoue H, et al. 2000. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem, 275:33951-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 33951-33956
-
-
Shao, J.1
Sheng, H.2
Inoue, H.3
-
74
-
-
0032160712
-
Role of cyclooxygenase-2 in the healing of gastric ulcers in rats
-
Shigeta J, Takahashi S, Okabe S. 1998. Role of cyclooxygenase-2 in the healing of gastric ulcers in rats. J Pharmacol Exp Ther, 286:1383-90.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 1383-1390
-
-
Shigeta, J.1
Takahashi, S.2
Okabe, S.3
-
75
-
-
4143107932
-
Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition
-
Simmons DL, Botting RM, Hla T. 2004. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol Rev, 56:387-437.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 387-437
-
-
Simmons, D.L.1
Botting, R.M.2
Hla, T.3
-
76
-
-
0033791318
-
Cyclooxygenases: Structural, cellular, and molecular biology
-
Smith W, DeWitt D, Garavito R. 2000. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem, 69:145-82.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 145-182
-
-
Smith, W.1
DeWitt, D.2
Garavito, R.3
-
77
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Solomon SD, McMurray JJ, Pfeffer MA, et al. 2005. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med, 352:1071-80.
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
-
78
-
-
42449093389
-
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials. The Cross Trial Safety Analysis
-
Solomon SD, Wittes J, Finn PV, et al. 2008. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials. The Cross Trial Safety Analysis. Circulation, 117:2104-13.
-
(2008)
Circulation
, vol.117
, pp. 2104-2113
-
-
Solomon, S.D.1
Wittes, J.2
Finn, P.V.3
-
79
-
-
0030995430
-
Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid
-
Swinney DC, Mak AY, Barnett J, et al. 1997. Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid. J Biol Chem, 272:12393-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 12393-12398
-
-
Swinney, D.C.1
Mak, A.Y.2
Barnett, J.3
-
80
-
-
0036966124
-
The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity
-
Tacconelli S, Capone ML, Sciulli MG, et al. 2002. The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. Curr Med Res Opin, 18:503-11.
-
(2002)
Curr Med Res Opin
, vol.18
, pp. 503-511
-
-
Tacconelli, S.1
Capone, M.L.2
Sciulli, M.G.3
-
81
-
-
0031766198
-
Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats
-
Takahashi S, Shigeta J, Inoue H, et al. 1998. Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats. Am J Physiol, 275:G1137-45.
-
(1998)
Am J Physiol
, vol.275
-
-
Takahashi, S.1
Shigeta, J.2
Inoue, H.3
-
82
-
-
0032929318
-
Possible involvement of interleukin-1 in cyclooxygenase-2 induction after spinal cord injury in rats
-
Tonai T, Taketani Y, Ueda N, et al. 1999. Possible involvement of interleukin-1 in cyclooxygenase-2 induction after spinal cord injury in rats. J Neurochem, 72:302-9.
-
(1999)
J Neurochem
, vol.72
, pp. 302-309
-
-
Tonai, T.1
Taketani, Y.2
Ueda, N.3
-
84
-
-
29244449354
-
Prostaglandins and cancer
-
Wang D, Dubois RN. 2006. Prostaglandins and cancer. Gut, 55:115-22.
-
(2006)
Gut
, vol.55
, pp. 115-122
-
-
Wang, D.1
Dubois, R.N.2
-
85
-
-
16344383840
-
Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial
-
Wiesenhutter CW, Boice JA, Ko A, et al. 2005. Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: a randomized, double-blind, placebo-controlled trial. Mayo Clin Proc, 80:470-9.
-
(2005)
Mayo Clin Proc
, vol.80
, pp. 470-479
-
-
Wiesenhutter, C.W.1
Boice, J.A.2
Ko, A.3
-
86
-
-
0026095297
-
Role of prostaglandins in gastroduodenal mucosal protection
-
Wilson DE. 1991. Role of prostaglandins in gastroduodenal mucosal protection. J Clin Gastroenterol, 13:S65-71.
-
(1991)
J Clin Gastroenterol
, vol.13
-
-
Wilson, D.E.1
-
87
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Andreasson KI, Kaufmann WE, et al. 1993. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron, 11:371-86.
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
-
88
-
-
33847726307
-
Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality
-
Yu Y, Fan J, Hui Y, et al. 2007. Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality. J Biol Chem, 282:1498-506.
-
(2007)
J Biol Chem
, vol.282
, pp. 1498-1506
-
-
Yu, Y.1
Fan, J.2
Hui, Y.3
|