메뉴 건너뛰기




Volumn 1144, Issue , 2008, Pages 61-73

Substance P in stress and anxiety: NK-1 receptor antagonism interacts with key brain areas of the stress circuitry

Author keywords

Antidepressant; Anxiety; Anxiolytic; Depression; Emotional behavior; HPA axis; In vivo release; Microdialysis; Neurokinin; NK 1 receptor; NK 1 receptor antagonist; Stress; Stress related disorders; Substance P; Tachykinin

Indexed keywords

DRUG VEHICLE; L 822429; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; PROTEIN C FOS; SUBSTANCE P; UNCLASSIFIED DRUG;

EID: 56649105314     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1418.018     Document Type: Conference Paper
Times cited : (82)

References (76)
  • 1
    • 0028067379 scopus 로고
    • Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats
    • &
    • Krase, W., M. Koch & H.U. Schnitzler. 1994. Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats. Behav. Brain Res. 63 : 81 88.
    • (1994) Behav. Brain Res. , vol.63 , pp. 81-88
    • Krase, W.1    Koch, M.2    Schnitzler, H.U.3
  • 3
    • 0020592730 scopus 로고
    • Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor
    • Nawa, H., T. Hirose, H. Takashima, et al. 1983. Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor. Nature 306 : 32 36.
    • (1983) Nature , vol.306 , pp. 32-36
    • Nawa, H.1    Hirose, T.2    Takashima, H.3
  • 4
    • 0027523466 scopus 로고
    • Neurotransmitter functions of mammalian tachykinins
    • &
    • Otsuka, M. & K. Yoshioka. 1993. Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73 : 229 308.
    • (1993) Physiol. Rev. , vol.73 , pp. 229-308
    • Otsuka, M.1    Yoshioka, K.2
  • 5
    • 0028589913 scopus 로고
    • Receptors and antagonists for substance P and related peptides
    • &
    • Regoli, D., A. Boudon & J.L. Fauchere. 1994. Receptors and antagonists for substance P and related peptides. Pharmacol. Rev. 46 : 551 599.
    • (1994) Pharmacol. Rev. , vol.46 , pp. 551-599
    • Regoli, D.1    Boudon, A.2    Fauchere, J.L.3
  • 6
    • 0029057535 scopus 로고
    • The mammalian tachykinin receptors
    • Maggi, C.A. 1995. The mammalian tachykinin receptors. Gen. Pharmacol. 26 : 911 944.
    • (1995) Gen. Pharmacol. , vol.26 , pp. 911-944
    • Maggi, C.A.1
  • 7
    • 0033745545 scopus 로고    scopus 로고
    • Neuroanatomical localisation of substance P in the CNS and sensory neurons
    • &
    • Ribeiro-da-Silva, A. & T. Hökfelt. 2000. Neuroanatomical localisation of substance P in the CNS and sensory neurons. Neuropeptides 34 : 256 271.
    • (2000) Neuropeptides , vol.34 , pp. 256-271
    • Ribeiro-Da-Silva, A.1    Hökfelt, T.2
  • 8
    • 84872828339 scopus 로고    scopus 로고
    • The histochemistry of tachykinin systems in the brain
    • & In. P. Holzer, Ed.: Springer. Heidelberg, Germany.
    • Hökfelt, T., E. Kuteeva, D. Stanic & A. Ljungdahl. 2004. The histochemistry of tachykinin systems in the brain. In Tachykinins. P. Holzer, Ed. : 63 120. Springer. Heidelberg, Germany.
    • (2004) Tachykinins. , pp. 63-120
    • Hökfelt, T.1    Kuteeva, E.2    Stanic, D.3    Ljungdahl, A.4
  • 9
    • 0023217740 scopus 로고
    • Coexistence of peptides with classical neurotransmitters
    • Hökfelt, T., D. Millhorn, K. Seroogy, et al. 1987. Coexistence of peptides with classical neurotransmitters. Experientia 43 : 768 780.
    • (1987) Experientia , vol.43 , pp. 768-780
    • Hökfelt, T.1    Millhorn, D.2    Seroogy, K.3
  • 10
    • 0036217385 scopus 로고    scopus 로고
    • Costorage and coexistence of neuropeptides in the mammalian CNS
    • Merighi, A. 2002. Costorage and coexistence of neuropeptides in the mammalian CNS. Prog. Neurobiol. 66 : 161 190.
    • (2002) Prog. Neurobiol. , vol.66 , pp. 161-190
    • Merighi, A.1
  • 11
    • 0023758981 scopus 로고
    • Substance P induces a cardiovascular defense reaction in the rat: Pharmacological characterization
    • Unger, T., S. Carolus, G. Demmert, D. Ganten, et al. 1988. Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization. Circ. Res. 63 : 812 820.
    • (1988) Circ. Res. , vol.63 , pp. 812-820
    • Unger, T.1    Carolus, S.2    Demmert, G.3    Ganten, D.4
  • 12
    • 0028884919 scopus 로고
    • Central tachykinins: Mediators of defence reaction and stress reactions
    • &
    • Culman, J. & T. Unger. 1995. Central tachykinins: mediators of defence reaction and stress reactions. Can. J. Physiol. Pharmacol. 73 : 885 891.
    • (1995) Can. J. Physiol. Pharmacol. , vol.73 , pp. 885-891
    • Culman, J.1    Unger, T.2
  • 13
    • 17844404803 scopus 로고    scopus 로고
    • Substance P receptor antagonists in psychiatry: Rationale for development and therapeutic potential
    • &
    • Herpfer, I. & K. Lieb. 2005. Substance P receptor antagonists in psychiatry: rationale for development and therapeutic potential. CNS Drugs 19 : 275 293.
    • (2005) CNS Drugs , vol.19 , pp. 275-293
    • Herpfer, I.1    Lieb, K.2
  • 14
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer, M.S., N. Cutler, J. Feighner, et al. 1998. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 281 : 1640 1645.
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3
  • 15
    • 0033410218 scopus 로고    scopus 로고
    • The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala
    • Smith, D.W., L. Hewson, P. Fuller, et al. 1999. The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala. Brain Res. 848 : 90 95.
    • (1999) Brain Res. , vol.848 , pp. 90-95
    • Smith, D.W.1    Hewson, L.2    Fuller, P.3
  • 16
    • 0036896930 scopus 로고    scopus 로고
    • SSR240600 (R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl acetyl]-2-(3,4-dichloro phenyl)-2-morpholinyl]ethyl]-4-piperidinyl)-2- methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin 1 receptor: II. Neurochemical and behavioral characterization
    • Steinberg, R., R. Alonso, L. Rouquier, et al. 2002. SSR240600 (R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl acetyl]-2-(3,4-dichloro phenyl)-2-morpholinyl]ethyl]-4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin 1 receptor: II. Neurochemical and behavioral characterization. J. Pharmacol. Exp. Ther. 303 : 1180 1188.
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 1180-1188
    • Steinberg, R.1    Alonso, R.2    Rouquier, L.3
  • 17
    • 10444276636 scopus 로고    scopus 로고
    • Vasopressin and oxytocin release within the brain: A dynamic concept of multiple and variable modes of neuropeptide communication
    • &
    • Landgraf, R. & I.D. Neumann. 2004. Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication. Front. Neuroendocrinol. 25 : 150 176.
    • (2004) Front. Neuroendocrinol. , vol.25 , pp. 150-176
    • Landgraf, R.1    Neumann, I.D.2
  • 18
    • 44649093249 scopus 로고    scopus 로고
    • Listening to neuropeptides by microdialysis: Echoes and new sounds?
    • &
    • Wotjak, C.T., R. Landgraf & M. Engelmann. 2008. Listening to neuropeptides by microdialysis: Echoes and new sounds? Pharmacol. Biochem. Behav. 90 : 125 134.
    • (2008) Pharmacol. Biochem. Behav. , vol.90 , pp. 125-134
    • Wotjak, C.T.1    Landgraf, R.2    Engelmann, M.3
  • 19
    • 0020651049 scopus 로고
    • Potassium evoked in vivo release of substance P in rat caudate nucleus measured using a new technique of brain dialysis and an improved substance P-radioimmunoassay
    • &
    • Brodin, E., N. Lindefors & U. Ungerstedt. 1983. Potassium evoked in vivo release of substance P in rat caudate nucleus measured using a new technique of brain dialysis and an improved substance P-radioimmunoassay. Acta Physiol. Scand. Suppl. 515 : 17 20.
    • (1983) Acta Physiol. Scand. Suppl. , vol.515 , pp. 17-20
    • Brodin, E.1    Lindefors, N.2    Ungerstedt, U.3
  • 20
    • 33749556143 scopus 로고    scopus 로고
    • The role of substance P in stress and anxiety responses
    • &
    • Ebner, K. & N. Singewald. 2006. The role of substance P in stress and anxiety responses. Amino Acids 31 : 251 272.
    • (2006) Amino Acids , vol.31 , pp. 251-272
    • Ebner, K.1    Singewald, N.2
  • 21
    • 1642488331 scopus 로고    scopus 로고
    • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
    • &
    • Ebner, K., N.M. Rupniak, A. Saria & N. Singewald. 2004. Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proc. Natl. Acad. Sci. USA 101 : 4280 4285.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4280-4285
    • Ebner, K.1    Rupniak, N.M.2    Saria, A.3    Singewald, N.4
  • 22
    • 45149100927 scopus 로고    scopus 로고
    • Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission
    • Ebner, K., G.M. Singewald, N. Whittle, et al. 2008. Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission. Neuropsychopharmacology 33 : 1929 1941.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1929-1941
    • Ebner, K.1    Singewald, G.M.2    Whittle, N.3
  • 23
    • 0020061543 scopus 로고
    • Distribution of neuropeptides in the limbic system of the rat: The amygdaloid complex
    • &
    • Roberts, G.W., P.L. Woodhams, J.M. Polak & T.J. Crow. 1982. Distribution of neuropeptides in the limbic system of the rat: the amygdaloid complex. Neuroscience 7 : 99 131.
    • (1982) Neuroscience , vol.7 , pp. 99-131
    • Roberts, G.W.1    Woodhams, P.L.2    Polak, J.M.3    Crow, T.J.4
  • 24
    • 0022922583 scopus 로고
    • Effect of immobilization stress on neuropeptides and their receptors in rat central nervous system
    • &
    • Takayama, H., Z. Ota & N. Ogawa. 1986. Effect of immobilization stress on neuropeptides and their receptors in rat central nervous system. Regul. Pept. 15 : 239 248.
    • (1986) Regul. Pept. , vol.15 , pp. 239-248
    • Takayama, H.1    Ota, Z.2    Ogawa, N.3
  • 25
    • 0028928491 scopus 로고
    • Rapid endocytosis of a G protein-coupled receptor: Substance P evoked internalization of its receptor in the rat striatum in vivo
    • Mantyh, P.W., C.J. Allen, J.R. Ghilardi, et al. 1995. Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo. Proc. Natl. Acad. Sci. USA 92 : 2622 2626.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2622-2626
    • Mantyh, P.W.1    Allen, C.J.2    Ghilardi, J.R.3
  • 26
    • 38449098153 scopus 로고    scopus 로고
    • Stress-induced release of substance P in the locus coeruleus modulates cortical noradrenaline release
    • &
    • Ebner, K. & N. Singewald. 2007. Stress-induced release of substance P in the locus coeruleus modulates cortical noradrenaline release. Naunyn-Schmiedebergs. Arch. Pharmacol. 376 : 73 82.
    • (2007) Naunyn-Schmiedebergs. Arch. Pharmacol. , vol.376 , pp. 73-82
    • Ebner, K.1    Singewald, N.2
  • 27
    • 34447291072 scopus 로고    scopus 로고
    • Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses
    • Berton, O., H.E. Covington 3rd., K. Ebner, et al. 2007. Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron 55 : 289 300.
    • (2007) Neuron , vol.55 , pp. 289-300
    • Berton, O.1    Covington III, H.E.2    Ebner, K.3
  • 28
  • 29
    • 1042276551 scopus 로고    scopus 로고
    • Invited review: The evolution of antidepressant mechanisms
    • &
    • Slattery, D.A., A.L. Hudson & D.J. Nutt. 2004. Invited review: the evolution of antidepressant mechanisms. Fundam. Clin. Pharmacol. 18 : 1 21.
    • (2004) Fundam. Clin. Pharmacol. , vol.18 , pp. 1-21
    • Slattery, D.A.1    Hudson, A.L.2    Nutt, D.J.3
  • 30
    • 50849110478 scopus 로고    scopus 로고
    • Modulation of basal and stress-induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L-822429
    • Singewald, N., G.G. Chicchi, C.C. Thurner, et al. 2008. Modulation of basal and stress-induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L-822429. J. Neurochem. 106 : 2476 2488.
    • (2008) J. Neurochem. , vol.106 , pp. 2476-2488
    • Singewald, N.1    Chicchi, G.G.2    Thurner, C.C.3
  • 31
    • 0036751063 scopus 로고    scopus 로고
    • High vs low anxiety-related behavior rats: An animal model of extremes in trait anxiety
    • &
    • Landgraf, R. & A. Wigger. 2002. High vs low anxiety-related behavior rats: an animal model of extremes in trait anxiety. Behav. Genet. 32 : 301 314.
    • (2002) Behav. Genet. , vol.32 , pp. 301-314
    • Landgraf, R.1    Wigger, A.2
  • 32
    • 33749568831 scopus 로고    scopus 로고
    • Differences in substance P neurotransmission between rats with high vs. low trait anxiety/depression [abstract]
    • Sartori, S.B., K. Ebner, P. Muigg, et al. 2005. Differences in substance P neurotransmission between rats with high vs. low trait anxiety/depression [abstract]. J. Neurochem. 94 : 229.
    • (2005) J. Neurochem. , vol.94 , pp. 229
    • Sartori, S.B.1    Ebner, K.2    Muigg, P.3
  • 33
    • 85047696280 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression
    • Geracioti, T.D. Jr., L.L. Carpenter, M.J. Owens, et al. 2006. Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression. Am. J. Psychiatry 163 : 637 643.
    • (2006) Am. J. Psychiatry , vol.163 , pp. 637-643
    • Geracioti Jr., T.D.1    Carpenter, L.L.2    Owens, M.J.3
  • 34
    • 33947590288 scopus 로고    scopus 로고
    • Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system
    • Michelgard, A., L. Appel, A. Pissiota, et al. 2007. Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system. Biol. Psychiatry 61 : 1002 1006.
    • (2007) Biol. Psychiatry , vol.61 , pp. 1002-1006
    • Michelgard, A.1    Appel, L.2    Pissiota, A.3
  • 35
    • 0027460680 scopus 로고
    • Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system
    • Whitnall, M.H. 1993. Regulation of the hypothalamic corticotropin- releasing hormone neurosecretory system. Prog. Neurobiol. 40 : 573 629.
    • (1993) Prog. Neurobiol. , vol.40 , pp. 573-629
    • Whitnall, M.H.1
  • 36
    • 0022820123 scopus 로고
    • Hypothalamic control of adrenocorticotropin secretion: Advances since the discovery of 41-residue corticotropin-releasing factor
    • Antoni, F.A. 1986. Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocr. Rev. 7 : 351 378.
    • (1986) Endocr. Rev. , vol.7 , pp. 351-378
    • Antoni, F.A.1
  • 37
    • 0032710993 scopus 로고    scopus 로고
    • Stress-induced c-fos expression in the rat locus coeruleus is dependent on neurokinin 1 receptor activation
    • &
    • Hahn, M.K. & M.J. Bannon. 1999. Stress-induced c-fos expression in the rat locus coeruleus is dependent on neurokinin 1 receptor activation. Neuroscience 94 : 1183 1188.
    • (1999) Neuroscience , vol.94 , pp. 1183-1188
    • Hahn, M.K.1    Bannon, M.J.2
  • 38
    • 56649096924 scopus 로고    scopus 로고
    • Reduced depression-like behaviour in HAB rats after NK1-receptor antagonist treatment is associated with an altered neuronal activation pattern in specific brain areas [abstract]
    • Muigg, P., S.B. Sartori, T. Sparber, et al. 2005. Reduced depression-like behaviour in HAB rats after NK1-receptor antagonist treatment is associated with an altered neuronal activation pattern in specific brain areas [abstract]. Abstract at the Meeting of the Austrian Neuroscience Association.
    • (2005) Abstract at the Meeting of the Austrian Neuroscience Association.
    • Muigg, P.1    Sartori, S.B.2    Sparber, T.3
  • 39
    • 0032495868 scopus 로고    scopus 로고
    • Tachykinin NK1 receptor antagonists enhance stress-induced c-fos in rat locus coeruleus
    • &
    • Hahn, M.K. & M.J. Bannon. 1998. Tachykinin NK1 receptor antagonists enhance stress-induced c-fos in rat locus coeruleus. Eur. J. Pharmacol. 348 : 155 160.
    • (1998) Eur. J. Pharmacol. , vol.348 , pp. 155-160
    • Hahn, M.K.1    Bannon, M.J.2
  • 40
    • 0036452457 scopus 로고    scopus 로고
    • Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1)
    • &
    • Santarelli, L., G. Gobbi, P. Blier & R. Hen. 2002. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). J. Clin. Psychiatry 63 (Suppl. 11 11 17.
    • (2002) J. Clin. Psychiatry , vol.63 , Issue.11 , pp. 11-17
    • Santarelli, L.1    Gobbi, G.2    Blier, P.3    Hen, R.4
  • 41
    • 39049172802 scopus 로고    scopus 로고
    • Genetic background influences the behavioural and molecular consequences of neurokinin-1 receptor knockout
    • McCutcheon, J.E., A.S. Fisher, E. Guzdar, et al. 2008. Genetic background influences the behavioural and molecular consequences of neurokinin-1 receptor knockout. Eur. J. Neurosci. 27 : 683 690.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 683-690
    • McCutcheon, J.E.1    Fisher, A.S.2    Guzdar, E.3
  • 42
    • 0029868295 scopus 로고    scopus 로고
    • Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety
    • &
    • Duncan, G.E., D.J. Knapp & G.R. Breese. 1996. Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety. Brain Res. 713 : 79 91.
    • (1996) Brain Res. , vol.713 , pp. 79-91
    • Duncan, G.E.1    Knapp, D.J.2    Breese, G.R.3
  • 43
    • 0027202723 scopus 로고
    • Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze
    • &
    • Silveira, M.C., G. Sandner & F.G. Graeff. 1993. Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze. Behav. Brain Res. 56 : 115 118.
    • (1993) Behav. Brain Res. , vol.56 , pp. 115-118
    • Silveira, M.C.1    Sandner, G.2    Graeff, F.G.3
  • 44
    • 0028318121 scopus 로고
    • Raised corticosterone in the rat after exposure to the elevated plus-maze
    • &
    • File, S.E., H. Zangrossi, Jr., F.L. Sanders & P.S. Mabbutt. 1994. Raised corticosterone in the rat after exposure to the elevated plus-maze. Psychopharmacology 113 : 543 546.
    • (1994) Psychopharmacology , vol.113 , pp. 543-546
    • File, S.E.1    Zangrossi Jr., H.2    Sanders, F.L.3    Mabbutt, P.S.4
  • 45
    • 0033430166 scopus 로고    scopus 로고
    • Corticosterone response to the plus-maze: High correlation with risk assessment in rats and mice
    • Rodgers, R.J., J. Haller, A. Holmes, et al. 1999. Corticosterone response to the plus-maze: high correlation with risk assessment in rats and mice. Physiol. Behav. 68 : 47 53.
    • (1999) Physiol. Behav. , vol.68 , pp. 47-53
    • Rodgers, R.J.1    Haller, J.2    Holmes, A.3
  • 47
    • 0037441837 scopus 로고    scopus 로고
    • Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs
    • &
    • Singewald, N., P. Salchner & T. Sharp. 2003. Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs. Biol. Psychiatry 53 : 275 283.
    • (2003) Biol. Psychiatry , vol.53 , pp. 275-283
    • Singewald, N.1    Salchner, P.2    Sharp, T.3
  • 48
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • &
    • Pellow, S., P. Chopin, S.E. File & M. Briley. 1985. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods 14 : 149 167.
    • (1985) J. Neurosci. Methods , vol.14 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 49
    • 17544368021 scopus 로고    scopus 로고
    • Strategies for producing faster acting antidepressants
    • Adell, A., E. Castro, P. Celada, et al. 2005. Strategies for producing faster acting antidepressants. Drug Discov. Today 10 : 578 585.
    • (2005) Drug Discov. Today , vol.10 , pp. 578-585
    • Adell, A.1    Castro, E.2    Celada, P.3
  • 50
    • 33845347420 scopus 로고    scopus 로고
    • Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping
    • Singewald, N. 2007. Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping. Neurosci. Biobehav. Rev. 31 : 18 40.
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 18-40
    • Singewald, N.1
  • 51
    • 0032191915 scopus 로고    scopus 로고
    • C-Fos as a transcription factor: A stressful (re)view from a functional map
    • Kovacs, K.J. 1998. c-Fos as a transcription factor: a stressful (re)view from a functional map. Neurochem. Int. 33 : 287 297.
    • (1998) Neurochem. Int. , vol.33 , pp. 287-297
    • Kovacs, K.J.1
  • 52
    • 0036212181 scopus 로고    scopus 로고
    • Anatomical markers of activity in neuroendocrine systems: Are we all 'fos-ed out'?
    • &
    • Hoffman, G.E. & D. Lyo. 2002. Anatomical markers of activity in neuroendocrine systems: Are we all 'fos-ed out'? J. Neuroendocrinol. 14 : 259 268.
    • (2002) J. Neuroendocrinol. , vol.14 , pp. 259-268
    • Hoffman, G.E.1    Lyo, D.2
  • 53
    • 0022857739 scopus 로고
    • Regulation of multiple peptides in CRF parvocellular neurosecretory neurons: Implications for the stress response
    • &
    • Swanson, L.W., P.E. Sawchenko & R.W. Lind. 1986. Regulation of multiple peptides in CRF parvocellular neurosecretory neurons: implications for the stress response. Prog. Brain Res. 68 : 169 190.
    • (1986) Prog. Brain Res. , vol.68 , pp. 169-190
    • Swanson, L.W.1    Sawchenko, P.E.2    Lind, R.W.3
  • 54
    • 0024508241 scopus 로고
    • Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues
    • &
    • Mantyh, P.W., T. Gates, C.R. Mantyh & J.E. Maggio. 1989. Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues. J. Neurosci. 9 : 258 279.
    • (1989) J. Neurosci. , vol.9 , pp. 258-279
    • Mantyh, P.W.1    Gates, T.2    Mantyh, C.R.3    Maggio, J.E.4
  • 55
    • 0029847171 scopus 로고    scopus 로고
    • The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress
    • Sawchenko, P.E., E.R. Brown, R.K. Chan, et al. 1996. The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress. Prog. Brain Res. 107 : 201 222.
    • (1996) Prog. Brain Res. , vol.107 , pp. 201-222
    • Sawchenko, P.E.1    Brown, E.R.2    Chan, R.K.3
  • 56
    • 0031913534 scopus 로고    scopus 로고
    • Hypothalamic effector neurons and extended circuitries activated in "neurogenic" stress: A comparison of footshock effects exerted acutely, chronically, and in animals with controlled glucocorticoid levels
    • &
    • Li, H.Y. & P.E. Sawchenko. 1998. Hypothalamic effector neurons and extended circuitries activated in "neurogenic" stress: a comparison of footshock effects exerted acutely, chronically, and in animals with controlled glucocorticoid levels. J. Comp. Neurol. 393 : 244 266.
    • (1998) J. Comp. Neurol. , vol.393 , pp. 244-266
    • Li, H.Y.1    Sawchenko, P.E.2
  • 57
    • 34250169392 scopus 로고    scopus 로고
    • Involvement of NK1 receptors in metabolic stress markers after the central administration of substance P
    • Mello, D.M., D.R. Marcinichen, D. Madruga, et al. 2007. Involvement of NK1 receptors in metabolic stress markers after the central administration of substance P. Behav. Brain Res. 181 : 232 238.
    • (2007) Behav. Brain Res. , vol.181 , pp. 232-238
    • Mello, D.M.1    Marcinichen, D.R.2    Madruga, D.3
  • 58
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
    • Santarelli, L., G. Gobbi, P.C. Debs, et al. 2001. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc. Natl. Acad. Sci. USA 98 : 1912 1917.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1912-1917
    • Santarelli, L.1    Gobbi, G.2    Debs, P.C.3
  • 59
    • 0035218323 scopus 로고    scopus 로고
    • Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs
    • Rupniak, N.M., E.J. Carlson, J.K. Webb, et al. 2001. Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs. Behav. Pharmacol. 12 : 497 508.
    • (2001) Behav. Pharmacol. , vol.12 , pp. 497-508
    • Rupniak, N.M.1    Carlson, E.J.2    Webb, J.K.3
  • 60
    • 0030851729 scopus 로고    scopus 로고
    • Diazepam attenuation of restraint stress-induced corticosterone levels is enhanced by prior exposure to repeated restraint
    • Kalman, B.A., P.J. Kim, M.A. Cole, et al. 1997. Diazepam attenuation of restraint stress-induced corticosterone levels is enhanced by prior exposure to repeated restraint. Psychoneuroendocrinology 22 : 349 360.
    • (1997) Psychoneuroendocrinology , vol.22 , pp. 349-360
    • Kalman, B.A.1    Kim, P.J.2    Cole, M.A.3
  • 61
    • 0029120572 scopus 로고
    • Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN)
    • Imaki, T., X.Q. Wang, T. Shibasaki, et al. 1995. Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN). Brain Res. Mol. Brain Res. 32 : 261 270.
    • (1995) Brain Res. Mol. Brain Res. , vol.32 , pp. 261-270
    • Imaki, T.1    Wang, X.Q.2    Shibasaki, T.3
  • 62
    • 3843117595 scopus 로고    scopus 로고
    • Regulation of affect by the lateral septum: Implications for neuropsychiatry
    • &
    • Sheehan, T.P., R.A. Chambers & D.S. Russell. 2004. Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Res. Brain Res. Rev. 46 : 71 117.
    • (2004) Brain Res. Brain Res. Rev. , vol.46 , pp. 71-117
    • Sheehan, T.P.1    Chambers, R.A.2    Russell, D.S.3
  • 63
    • 84942593534 scopus 로고    scopus 로고
    • The septal region
    • In. G. Paxinos, Ed.: Academic Press. New York.
    • Risold, P.Y. 2004. The septal region. In The Rat Nervous System. G. Paxinos, Ed. : 605 632. Academic Press. New York.
    • (2004) The Rat Nervous System. , pp. 605-632
    • Risold, P.Y.1
  • 64
    • 0030842173 scopus 로고    scopus 로고
    • Chemoarchitecture of the rat lateral septal nucleus
    • &
    • Risold, P.Y. & L.W. Swanson. 1997. Chemoarchitecture of the rat lateral septal nucleus. Brain Res. Brain Res. Rev. 24 : 91 113.
    • (1997) Brain Res. Brain Res. Rev. , vol.24 , pp. 91-113
    • Risold, P.Y.1    Swanson, L.W.2
  • 65
    • 0030730894 scopus 로고    scopus 로고
    • Connections of the rat lateral septal complex
    • &
    • Risold, P.Y. & L.W. Swanson. 1997. Connections of the rat lateral septal complex. Brain Res. Brain Res. Rev. 24 : 115 195.
    • (1997) Brain Res. Brain Res. Rev. , vol.24 , pp. 115-195
    • Risold, P.Y.1    Swanson, L.W.2
  • 66
    • 0038545294 scopus 로고    scopus 로고
    • Neural correlates of competing fear behaviors evoked by an innately aversive stimulus
    • &
    • Mongeau, R., G.A. Miller, E. Chiang & D.J. Anderson. 2003. Neural correlates of competing fear behaviors evoked by an innately aversive stimulus. J. Neurosci. 23 : 3855 3868.
    • (2003) J. Neurosci. , vol.23 , pp. 3855-3868
    • Mongeau, R.1    Miller, G.A.2    Chiang, E.3    Anderson, D.J.4
  • 67
    • 0025374493 scopus 로고
    • Efferent projections from the lateral septal nucleus to the anterior hypothalamus in the rat: A study combining Phaseolus vulgaris-leucoagglutinin tracing with vasopressin immunocytochemistry
    • &
    • Staiger, J.F. & F.G. Wouterlood. 1990. Efferent projections from the lateral septal nucleus to the anterior hypothalamus in the rat: a study combining Phaseolus vulgaris-leucoagglutinin tracing with vasopressin immunocytochemistry. Cell Tissue Res. 261 : 17 23.
    • (1990) Cell Tissue Res. , vol.261 , pp. 17-23
    • Staiger, J.F.1    Wouterlood, F.G.2
  • 68
    • 0242352373 scopus 로고    scopus 로고
    • Central mechanisms of stress integration: Hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness
    • Herman, J.P., H. Figueiredo, N.K. Mueller, et al. 2003. Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front. Neuroendocrinol. 24 : 151 180.
    • (2003) Front. Neuroendocrinol. , vol.24 , pp. 151-180
    • Herman, J.P.1    Figueiredo, H.2    Mueller, N.K.3
  • 69
    • 0037470082 scopus 로고    scopus 로고
    • Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety
    • &
    • Walker, D.L., D.J. Toufexis & M. Davis. 2003. Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety. Eur. J. Pharmacol. 463 : 199 216.
    • (2003) Eur. J. Pharmacol. , vol.463 , pp. 199-216
    • Walker, D.L.1    Toufexis, D.J.2    Davis, M.3
  • 70
    • 0030759513 scopus 로고    scopus 로고
    • Roles of the amygdala and bed nucleus of the stria terminalis in fear and anxiety measured with the acoustic startle reflex. Possible relevance to PTSD
    • &
    • Davis, M., D.L. Walker & Y. Lee. 1997. Roles of the amygdala and bed nucleus of the stria terminalis in fear and anxiety measured with the acoustic startle reflex. Possible relevance to PTSD. Ann. N.Y. Acad. Sci. 821 : 305 331.
    • (1997) Ann. N.Y. Acad. Sci. , vol.821 , pp. 305-331
    • Davis, M.1    Walker, D.L.2    Lee, Y.3
  • 71
    • 0034968997 scopus 로고    scopus 로고
    • Intra-amygdala injection of the substance P antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs K(1) receptor
    • Boyce, S., D. Smith, E. Carlson, et al. 2001. Intra-amygdala injection of the substance P antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs K(1) receptor. Neuropharmacology 41 : 130 137.
    • (2001) Neuropharmacology , vol.41 , pp. 130-137
    • Boyce, S.1    Smith, D.2    Carlson, E.3
  • 72
    • 15044344103 scopus 로고    scopus 로고
    • Neuropeptide expression in rats exposed to chronic mild stresses
    • Sergeyev, V., S. Fetissov, A.A. Mathe, et al. 2005. Neuropeptide expression in rats exposed to chronic mild stresses. Psychopharmacology 178 : 115 124.
    • (2005) Psychopharmacology , vol.178 , pp. 115-124
    • Sergeyev, V.1    Fetissov, S.2    Mathe, A.A.3
  • 73
    • 56649109094 scopus 로고    scopus 로고
    • Effects of Substance P in the amygdala, ventromedial hypothalamus, and periaqueductal gray on fear/potentiated startle
    • & In press.
    • Zhao, Z., Y. Yang, D.L. Walker & M. Davis. 2008. Effects of Substance P in the amygdala, ventromedial hypothalamus, and periaqueductal gray on fear/potentiated startle. Neuropsychopharmacology : In press.
    • (2008) Neuropsychopharmacology
    • Zhao, Z.1    Yang, Y.2    Walker, D.L.3    Davis, M.4
  • 74
    • 35648976015 scopus 로고    scopus 로고
    • Functional internal complexity of amygdala: Focus on gene activity mapping after behavioral training and drugs of abuse
    • &
    • Knapska, E., K. Radwanska, T. Werka & L. Kaczmarek. 2007. Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse. Physiol. Rev. 87 : 1113 1173.
    • (2007) Physiol. Rev. , vol.87 , pp. 1113-1173
    • Knapska, E.1    Radwanska, K.2    Werka, T.3    Kaczmarek, L.4
  • 75
    • 0032804099 scopus 로고    scopus 로고
    • Tachykinin receptor inhibition and c-Fos expression in the rat brain following formalin-induced pain
    • Baulmann, J., H. Spitznagel, T. Herdegen, et al. 2000. Tachykinin receptor inhibition and c-Fos expression in the rat brain following formalin-induced pain. Neuroscience 95 : 813 820.
    • (2000) Neuroscience , vol.95 , pp. 813-820
    • Baulmann, J.1    Spitznagel, H.2    Herdegen, T.3
  • 76
    • 22444442937 scopus 로고    scopus 로고
    • Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo
    • Furmark, T., L. Appel, A. Michelgard, et al. 2005. Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo. Biol. Psychiatry 58 : 132 142.
    • (2005) Biol. Psychiatry , vol.58 , pp. 132-142
    • Furmark, T.1    Appel, L.2    Michelgard, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.