Tachykinin receptor inhibition and c-Fos expression in the rat brain following formalin-induced pain

Neuroscience

Volumn 95, Issue 3, 1999, Pages 813-820

  Baulmann, J ^a   Spitznagel, H ^a   Herdegen, T ^a   Unger, T ^a   Culman, J ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Brain; Neurokinins; Pain; Rat; Substance P; Tachykinin receptor antagonists

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; FORMALDEHYDE; SAREDUTANT; TACHYKININ RECEPTOR; TRANSCRIPTION FACTOR;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BITE; BRAIN STEM; ENANTIOMER; GENE EXPRESSION; GROOMING; LICKING; LOCUS CERULEUS; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; ONCOGENE C FOS; PAIN; PERIAQUEDUCTAL GRAY MATTER; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; STRESS;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; BENZAMIDES; BRAIN; FORMALDEHYDE; GROOMING; INDOLES; INJECTIONS, INTRAVENTRICULAR; MALE; PAIN; PIPERIDINES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RECEPTORS, TACHYKININ;

EID: 0032804099     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00478-9     Document Type: Article

References (43)

1. Arnold F.J.L., de Lucas Bueno M., Shiers H., Hancock D.C., Evan G.I., Herbert J. Expression of c-fos in regions of the basal limbic forebrain following intracerebroventricular corticotropin-releasing factor in unstressed or stressed male rats. Neuroscience. 51:1992;377-390.
2. Bittencourt J.C., Benoit R., Sawchenko P.E. Distribution and origins of substance P-immunoreactive projections to the paraventricular and supraoptic nuclei: partial overlap with ascending catecholaminergic projections. J. chem. Neuroanat. 4:1991;63-78.
3. Buck S.H., Helke C.J., Burcher E., Shults C.W., O'Donohue T.L. Pharmacologic characterization and autoradiographic distribution of binding sites for iodinated tachykinins in the rat central nervous system. Peptides. 7:1986;1109-1120.
4. Campeau S., Hayward M.D., Hope B.T., Rosen J.B., Nestler E.J., Davis M. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear. Brain Res. 565:1991;349-352.
5. Ceccatelli S., Villar M.J., Goldstein M., Hökfelt T. Expression of c-Fos immunoreactivity in transmitter-characterized neurons after stress. Proc. natn. Acad. Sci. U.S.A. 86:1989;9569-9573.
6. Cheeseman H.J., Pinnock R.D., Henderson G. Substance P excitation of rat locus coeruleus neurones. Eur. J. Pharmac. 94:1983;93-99.
7. Chen X., Herbert J. Regional changes in c-fos expression in the basal forebrain and brainstem during adaptation to repeated stress: correlations with cardiovascular, hypothermic and endocrine responses. Neuroscience. 64:1995;675-685.
8. Cullinan W.E., Herman J.P., Battaglia D.F., Akil H., Watson S.J. Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience. 64:1995;477-505.
9. Culman J., Unger Th. Central tachykinins: mediators of defence reaction and stress reactions. Can. J. Physiol. Pharmac. 73:1995;885-891.
10. Culman J., Klee S., Ohlendorf C., Unger Th. Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioural responses to stress. J. Pharmac. exp. Ther. 280:1997;238-246.
11. Culman J., Ritter S., Ohlendorf C., Haass M., Maser-Gluth C., Unger Th. A new formalin test allowing simultaneous evaluation of cardiovascular and nociceptive responses. Can. J. Physiol. Pharmac. 75:1997;1203-1211.
12. 11]-substance P. Brain Res. 531:1990;333-337.
13. Dragunow M., Faull R. The use of c-fos as a metabolic marker in neuronal pathway tracing. J. Neurosci. Meth. 29:1989;261-265.
14. Duncan G.E., Knapp D.J., Johnson K.B., Breese G.R. Functional classification of antidepressants based on antagonism of swim stress-induced Fos-like immunoreactivity. J. Pharmac. exp. Ther. 277:1996;1076-1089.
15. 2) receptor. Life Sci. 50:1992;PL101-PL106.
16. 2 receptor. Drugs Future. 20:1993;701-707.
17. Fields H.L., Heinricher M.M., Mason P. Neurotransmitters in nociceptive modulatory circuits. A. Rev. Neurosci. 14:1991;219-245.
18. Garret C., Carruette A., Fardin V., Moussaoui S., Peyronel J.-F., Blanchard J.-C., Laduron P.M. Pharmacological properties of a potent and selective nonpeptide substance P antagonist. Proc. natn. Acad. Sci. U.S.A. 88:1991;10,208-10,212.
19. Gispen W.H., Wiegant V.M., Greven H.M., de Wied D. The induction of excessive grooming in the rat by intraventricular application of peptides derived from ACTH: structure-activity relationship. Life Sci. 17:1975;645-652.
20. Herbert H., Saper C. Cholecystokinin-, galanin-, and corticotropin releasing factor-like immunoreactive projections from the nucleus of the solitary tract to the parabrachial nucleus of the rat. J. comp. Neurol. 293:1990;581-598.
21. Herd J.A. Cardiovascular response to stress. Physiol. Rev. 71:1991;305-330.
22. Herdegen T., Kovary K., Leah J.D., Bravo R. Specific temporal and spatial distribution of JUN, FOS and KROX-24 proteins in spinal neurons following noxious transynaptic stimulation. J. comp. Neurol. 313:1991;178-191.
23. Hilton S.M., Redfern W.S. A search for brain stem cell groups integrating the defence reaction in the rat. J. Physiol. 378:1986;213-228.
24. Hunt S.P., Pini A., Evan G. Induction of c-fos like protein in spinal cord neurons following sensory stimulation. Nature. 328:1987;632-634.
25. Lima D., Coimbra A. The spinothalamic system of the rat: structural types of retrogradely labelled neurons in the marginal zone (lamina I). Neuroscience. 27:1988;215-230.
26. 2+ channels. Eur. J. Pharmac. 267:1994;113-115.
27. 1 receptor. Trends. pharmac. Sci. 18:1997;351-354.
28. Miller F.J. Jr, Marcus M.L., Brody M.J., Gutterman D. Activation in the region of parabrachial nucleus elicits neurogenically mediated coronary vasoconstriction. Am. J. Physiol. (Heart Circ. Physiol.). 261:1991;H1585-H1596.
29. Moga M.M., Gray T.S. Evidence for corticotropin-releasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus. J. comp. Neurol. 241:1985;275-284.
30. Morgan J.I., Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. A. Rev. Neurosci. 14:1991;421-451.
31. Otsuka M., Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73:1993;229-308.
32. Palkovits M., Baffi J.S., Dvori S. Neuronal organization of stress response. Ann. N. Y. Acad. Sci. 771:1995;313-326.
33. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd edn. Academic, San Diego, CA.
34. Pezzone M.A., Lee W.-S., Hoffman G., Rabin B.S. Induction of c-Fos immunoreactivity in the rat forebrain by conditioned and unconditioned aversive stimuli. Brain Res. 597:1992;41-50.
35. Pezzone M.A., Lee W.-S., Hoffman G., Pezzone K.M., Rabin B.S. Activation of brainstem catechoalaminergic neurons by conditioned and unconditioned aversive stimuli as revealed by c-Fos immunoreactivity. Brain Res. 608:1993;310-318.
36. Regoli D., Boudon A., Fauchére J.-L. Receptors and antagonists for substance P and related peptides. Pharmac. Rev. 46:1994;551-599.
37. Rosen A., Brodin K., Eneroth P., Brodin E. Short-term restraint stress and s.c. saline injection alter the tissue levels of substance P and cholecystokinin in the peri-aqueductal grey and limbic regions of rat brain. Acta physiol. scand. 146:1992;341-348.
38. Stratakis C.A., Chrousos G.P. Neuroendocrinology and pathophysiology of the stress system. Ann. N. Y. Acad. Sci. 771:1995;1-18.
39. Swanson L. W. (1987) The hypothalamus. In Handbook of Chemical Neuroanatomy, Vol. 5: Integrated Systems of the CNS, Part I (eds Björklund A., Hökfelt T. and Swanson L. W.), pp. 1-124. Elsevier, New York.
40. Swanson L.W., Sawchenko P.E., Lind R.W. Regulation of multiple peptides in CRF parvocellular neurosecretory neurons: implications for the stress response. Prog. Brain Res. 68:1986;169-190.
41. Unger Th., Carolus S., Demmert G., Ganten D., Lang R.E., Maser-Gluth C., Steinberg H., Veelken R. Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization. Circ. Res. 63:1988;812-820.
42. Wang Z.-Y., Tung S.R., Strichartz G.R., Hakanson R. Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission. Br. J. Pharmac. 111:1994;179-184.
43. Williams S., Evan G.I., Hunt S.P. Changing patterns of c-Fos induction in spinal neurons following thermal cutaneous stimulation in the rat. Neuroscience. 36:1990;73-81.