Cross-talk between the Akt and NF-κB signaling pathways inhibits MEHP-induced germ cell apoptosis

Toxicological Sciences

Volumn 106, Issue 2, 2008, Pages 497-508

  Rogers, Rachel ^a,b   Ouellet, Gregory ^b   Brown, Caitlin ^b   Moyer, Ben ^b   Rasoulpour, Teresa ^b   Hixon, Mary ^b  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Akt1; Germ cell; MEHP; NF B; Oxidative stress; Phthalates; Sertoli cell

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P50; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SUPEROXIDE; SYNAPTOTAGMIN I;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GERM CELL; MALE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PERINATAL PERIOD; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TESTIS INJURY; WILD TYPE;

ANIMALS; BASE SEQUENCE; BCL-X PROTEIN; BLOTTING, WESTERN; CARRIER PROTEINS; DIETHYLHEXYL PHTHALATE; DNA PRIMERS; MALE; MICE; MITOCHONDRIAL PROTEINS; NF-KAPPA B; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPERMATOZOA; SUPEROXIDES; TESTIS;

MUS;

EID: 56649093045     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn186     Document Type: Article

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