IκBα/IκBε deficiency reveals that a critical NF-κB dosage is required for lymphocyte survival

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15800-15805

  Goudeau, Bertrand ^a,d   Huetz, François ^b   Samson, Sandrine ^b   Di Santo, James P ^b   Cumano, Ana ^b   Beg, Amer ^c   Israël, Alain ^a   Mémet, Sylvie ^a  

^a CNRS   (France)

^b INSTITUT PASTEUR   (France)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Apoptosis; Chimera; I B; Mice; Transcription factor NF B Rel

Indexed keywords

I KAPPA B ALPHA; I KAPPA B BETA; I KAPPA B BETA EPSILON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; I KAPPA B; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NFKBIE PROTEIN, MOUSE; ONCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; GENE DISRUPTION; GENE OVEREXPRESSION; GENE TARGETING; LYMPHOCYTE; LYMPHOCYTOPOIESIS; MOUSE; NEWBORN DEATH; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN INTERACTION; T LYMPHOCYTE; ANIMAL; CYTOLOGY; GENE REARRANGEMENT; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANIMALIA;

ANIMALS; BASE SEQUENCE; CELL SURVIVAL; GENE REARRANGEMENT; I-KAPPA B PROTEINS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; LYMPHOCYTES; MICE; MICE, KNOCKOUT; NF-KAPPA B; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS;

EID: 0347994897     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2535880100     Document Type: Article

References (39)

1. Gerondakis, S., Grumont, R., Rourke, I. & Grossmann, M. (1998) Curr. Opin. Immunol. 10, 353-359.
2. Karin, M. & Lin, A. (2002) Nat. Immunol. 3, 221-227.
3. Li, Q. & Verma, I. M. (2002) Nat. Rev. Immunol. 2, 725-734.
4. Whiteside, S. T. & Israel, A. (1997) Semin. Cancer Biol. 8, 75-82.
5. Beg, A. A., Sha, W. C., Bronson, R. T. & Baltimore, D. (1995) Genes Dev. 9, 2736-2746.
6. Klement, J. F., Rice, N. R., Car, B. D., Abbondanzo, S. J., Powers, G. D., Bhatt, H., Chen, C. H., Rosen, C. A. & Stewart, C. L. (1996) Mol. Cell. Biol. 16, 2341-2349.
7. Mémet, S., Laouini, D., Epinat, J.-C., Whiteside, S. T., Goudeau, B., Philpott, D., Kayal, S., Sansonetti, P. J., Berche, P., Kanellopoulos, J. & Israël, A. (1999) J. Immunol. 163, 5994-6005.
8. Chen, C. L., Singh, N., Yull, F. E., Strayhorn, D., Van Kaer, L. & Kerr, L. D. (2000) J. Immunol. 165, 5418-5427.
9. Whiteside, S. T., Epinat, J. C., Rice, N. R. & Israel, A. (1997) EMBO J. 16, 1413-1426.
10. Schmidt-Ullrich, R., Mémet, S., Lilienbaum, A., Feuillard, J., Raphael, M. & Israël, A. (1996) Development (Cambridge, U.K.) 122, 2117-2128.
11. Feuillard, J., Mémet, S., Goudeau, B., Lilienbaum, A., Schmidt-Ullrich, R., Raphaël, M. & Israël, A. (2000) Int. Immunol. 12, 613-621.
12. Schlissel, M. S. & Baltimore, D. (1989) Cell 58, 1001-1007.
13. Marshall, A. J., Wu, G. E. & Paige, G. J. (1996) J. Immunol. 156, 2077-2084.
14. Goodhardt, M., Cavelier, P., Doyen, N., Kallenbach, S., Babinet, C. & Rougeon, F. (1993) Eur. J. Immunol. 23, 1789-1795.
15. Church, G. M. & Gilbert, W. (1984) Proc. Natl. Acad. Sci. USA 81, 1991-1995.
16. Colucci, F., Samson, S. I., DeKoter, R. P., Lantz, O., Singh, H. & Di Santo, J. P. (2001) Blood 97, 2600-2608.
17. Jarriault, S., Brou, C., Logeat, F., Schroeter, E. H., Kopan, R. & Israel, A. (1995) Nature 377, 355-358.
18. Petit, P. X., Lecoeur, H., Zorn, E., Dauguet, C., Mignotte, B. & Gougeon, M. L. (1995) J. Cell Biol. 130, 157-167.
19. Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssiere, J. L., Petit, P. X. & Kroemer, G. (1995) J. Exp. Med. 181, 1661-1672.
20. D'Mello, S., Aglicco, F., Roberts, M. R., Borodezt, K. & Haycock, J. W. (1998) J. Neurochem. 70, 1809-1818.
21. Colucci, F., Soudais, C., Rosmaraki, E., Vanes, L., Tybulewicz, V. L. & Di Santo, J. P. (1999) J. Immunol. 162, 2761-2765.
22. Horwitz, B. H., Scott, M. L., Cherry, S. R., Bronson, R. T. & Baltimore, D. (1997) Immunity 6, 765-772.
23. Mora, A. L., Stanley, S., Armistead, W., Chan, A. C. & Boothby, M. (2001) J. Immunol. 167, 5628-5635.
24. Kim, D., Xu, M., Nie, L., Peng, X. C., Jimi, E., Voll, R. E., Nguyen, T., Ghosh, S. & Sun, X. H. (2002) Immunity 16, 9-21.
25. Voll, R. E., Jimi, E., Phillips, R. J., Barber, D. F., Rincon, M., Hayday, A. C., Flavell, R. A. & Ghosh, S. (2000) Immunity 13, 677-689.
26. Gerondakis, S. & Strasser, A. (2001) Nat. Immunol. 2, 377-379.
27. Hettmann, T., DiDonato, J., Karin, M. & Leiden, J. M. (1999) J. Exp. Med. 189, 145-157.
28. Boothby, M. R., Mora, A. L., Scherer, D. C., Brockman, J. A. & Ballard, D. W. (1997) J. Exp. Med. 185, 1897-1907.
29. Dudley, E., Hornung, F., Zheng, L. X., Scherer, D., Ballard, D. & Lenardo, M. (1999) Eur. J. Immunol. 29, 878-886.
30. Zheng, Y., Vig, M., Lyons, J., Van Parijs, L. & Beg, A. A. (2003) J. Exp. Med. 197, 861-874.
31. Senftleben, U., Li, Z. W., Baud, V. & Karin, M. (2001) Immunity 14, 217-230.
32. Guerin, S., Baron, M. L., Valero, R., Herrant, M., Auberger, P. & Naquet, P. (2002) Eur. J. Immunol. 32, 1-9.
33. Sheehy, A. M. & Schlissel, M. S. (1999) J. Biol. Chem. 274, 8708-8716.
34. Grossmann, M., O'Reilly, L. A., Gugasyan, R., Strasser, A., Adams, J. M. & Gerondakis, S. (2000) EMBO J. 19, 6351-6360.
35. Li, Z. W., Omori, S. A., Labuda, T., Karin, M. & Rickert, R. C. (2003) J. Immunol. 170, 4630-4637.
36. Pasparakis, M., Schmidt-Supprian, M. & Rajewsky, K. (2002) J. Exp. Med. 196, 743-752.
37. Kim, S., La Motte-Mohs, R. N., Rudolph, D., Zuniga-Pflucker, J. C. & Mak, T. W. (2003) Proc. Natl. Acad. Sci. USA 100, 1203-1208.
38. Carsetti, R. (2000) J. Exp. Med. 191, 23-32.
39. Melchers, F., Rolink, A. G. & Schaniel, C. (1999) Cell 99, 351-354.